From: Multidisciplinary approaches to managing osteoarthritis in multiple joint sites: a systematic review
Studies & trial design | Sample size | Setting | Health disciplines | OA sites | Mean age of participants (SD) | Primary outcomes within studies | Secondary outcomes within studies | Key findings of studies |
---|---|---|---|---|---|---|---|---|
Hopman-Rock & Westhoff (2000) [16] RCT | N = 105 Intervention = 56 Control = 49 | Single Centre (Netherlands) Primary Care | Physiotherapy, Occupational Therapy (OT) and General Practitioner | Hip or Knee | Intervention =65.4 (5.3) Control =65.2 (5.7) | IRGL self-reported pain. Pain severity (VAS) | QoL (VAS) QoL seven question sum score Activity restriction, ROM Muscle strength Observed activity restrictions Healthcare utilisation, lifestyle behaviour, BMI | Significant MANOVA effects were found for pain, QoL, quadriceps, BMI, physically active lifestyle, and visits to the physical therapist. Most effects were moderate at post-test assessment and smaller at follow-up. No effects were found for range of ROM or functional tasks |
van Baar et al. (2001) [19] Single blind RCT | N = 201 Intervention = 99 Control = 102 | Multi-Centre (Netherlands) Primary Care | General Practitioner and Physiotherapy | Hip or Knee | Intervention 68.3 (8.4) Control =67.7 (9.2) | IRGL self-reported disability, VAS pain in the past week | Observed disability, Drug use NSAIDs/paracetamol, Global perceived effect, muscle strength & ROM hip, knee, physical activity | At 24 weeks exercise treatment was associated with a small to moderate effect on pain during the past week (difference in change between the two groups −11.5 (95 % CI −19.7 to −3.3). At 36 weeks no differences were found between groups. |
Rosemann et al. (2007) [18] 3-arm pragmatic cluster trial | N = 1021 Intervention 1 =345 Intervention 2 =344 Control = 332 | Multi-Centre (Germany) Primary Care | General Practitioner and Practice nurse | Hip or Knee | Intervention 1 = 65.59 (14.68) Intervention 2 = 66.27 (15.19) Control =66.11 (15.02) | AIMS2-SF QoL, lower body, upper body, symptom & social. | IPAQ physical activity, BMI, prescriptions. Health service utilisation | Compared with the control group, for intervention group II, significant changes in the AIMS2-SF dimensions social (p < 0.001), symptom (p = 0.048), and lower body (p = 0.049) were identified. Radiographs (P = 0.031) and orthopaedic referrals (p = 0.044) decreased whereas prescriptions of pain relievers increased significantly. |
Hansson et al. (2010) [17] Single blind RCT | N = 114 Intervention = 61 Control = 53 | Single Centre (Sweden) Primary Care | Physiotherapy, OT, Orthopaedic Specialist, Nurse, Nutritionist | Knee, Hip or Hand | Intervention =62 (9.43) Control =63 (9.51) | EQ5D index and EQ5D VAS | ASES pain, function & other symptoms. GAT, SOLEO, SOLEC, One legged jump/raising, OA location & BMI | Significant differences between the intervention group and the control group, comparing the results at baseline and after 6 months in EuroQol-5D (p < 0.001) and in SOLEC (p = 0.02) in favour of the intervention group. |