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Table 4 An overview and key findings of the four studies included in the review

From: Multidisciplinary approaches to managing osteoarthritis in multiple joint sites: a systematic review

Studies & trial design

Sample size

Setting

Health disciplines

OA sites

Mean age of participants (SD)

Primary outcomes within studies

Secondary outcomes within studies

Key findings of studies

Hopman-Rock & Westhoff (2000) [16]

RCT

N = 105

Intervention = 56

Control = 49

Single Centre

(Netherlands)

Primary Care

Physiotherapy, Occupational Therapy (OT) and General Practitioner

Hip or Knee

Intervention

=65.4 (5.3)

Control

=65.2 (5.7)

IRGL self-reported pain. Pain severity (VAS)

QoL (VAS)

QoL seven question sum score

Activity restriction, ROM

Muscle strength

Observed activity restrictions

Healthcare utilisation, lifestyle behaviour, BMI

Significant MANOVA effects were found for pain, QoL, quadriceps, BMI, physically active lifestyle, and visits to the physical therapist. Most effects were moderate at post-test assessment and smaller at follow-up. No effects were found for range of ROM or functional tasks

van Baar et al. (2001) [19]

Single blind RCT

N = 201

Intervention = 99

Control = 102

Multi-Centre (Netherlands)

Primary Care

General Practitioner and Physiotherapy

Hip or Knee

Intervention

68.3 (8.4)

Control

=67.7 (9.2)

IRGL self-reported disability, VAS pain in the past week

Observed disability, Drug use NSAIDs/paracetamol, Global perceived effect, muscle strength & ROM hip, knee, physical activity

At 24 weeks exercise treatment was associated with a small to moderate effect on pain during the past week (difference in change between the two groups −11.5 (95 % CI −19.7 to −3.3). At 36 weeks no differences were found between groups.

Rosemann et al. (2007) [18]

3-arm pragmatic cluster trial

N = 1021

Intervention 1

=345

Intervention 2

=344

Control = 332

Multi-Centre (Germany)

Primary Care

General Practitioner and Practice nurse

Hip or Knee

Intervention 1 = 65.59 (14.68)

Intervention 2 = 66.27 (15.19)

Control

=66.11 (15.02)

AIMS2-SF QoL, lower body, upper body, symptom & social.

IPAQ physical activity, BMI, prescriptions. Health service utilisation

Compared with the control group, for intervention group II, significant changes in the AIMS2-SF dimensions social (p < 0.001), symptom (p = 0.048), and lower body (p = 0.049) were identified. Radiographs (P = 0.031) and orthopaedic referrals (p = 0.044) decreased whereas prescriptions of pain relievers increased significantly.

Hansson et al. (2010) [17]

Single blind RCT

N = 114

Intervention = 61 Control = 53

Single Centre (Sweden)

Primary Care

Physiotherapy, OT, Orthopaedic Specialist, Nurse, Nutritionist

Knee, Hip or Hand

Intervention

=62 (9.43)

Control

=63 (9.51)

EQ5D index and EQ5D VAS

ASES pain, function & other symptoms. GAT, SOLEO, SOLEC, One legged jump/raising, OA location & BMI

Significant differences between the intervention group and the control group, comparing the results at baseline and after 6 months in EuroQol-5D (p < 0.001) and in SOLEC (p = 0.02) in favour of the intervention group.

  1. Key: AIMS2 Arthritis Impact Measurement Scale, ASES Arthritis Self-Efficacy Scale, BMI Body Mass Index, EQ-5D Euro QoL, European Quality of Life measure, GAT Grip Ability Test, IPAQ International Physical Activity Questionnaire, GP General Practitioner, IRGL Impact of Rheumatic Disease on General Health and Lifestyle, NSAIDs Non-steroidal anti-inflammatory drugs, QoL Quality of Life, ROM Range of Movement, VAS Visual Analogue Scale, SOLEO Stand On One Leg Eyes Open, SOLEC Stand On One Leg Eyes Closed