From: Development and feasibility of a personalized, interactive risk calculator for knee osteoarthritis
Input parameter | Possible values | |||
---|---|---|---|---|
Starting Age | 25Â years through 45Â years | Â | Â | |
Sex | Female | Â | Â | |
Male | Â | Â | ||
Race/ethnicity | White | Â | Â | |
Black | Â | Â | ||
Hispanic | Â | Â | ||
Obesity status | Obese | Â | Â | |
Non-obese | Â | Â | ||
Family history | Family history | Â | Â | |
No family history | Â | Â | ||
Occupational exposure | Present | Â | Â | |
Absent | Â | Â | ||
History of knee injury | Present | Â | Â | |
Absent | Â | Â | ||
OA Incidence (annual probability, %) | Â | Â | ||
Age Range | Non-obese male | Non-obese female | Obese Male | Obese Female |
25–34 | 0.12 | 0.14 | 0.25 | 0.38 |
35–44 | 0.13 | 0.15 | 0.25 | 0.41 |
45–54 | 0.23 | 0.28 | 0.47 | 0.62 |
55–64 | 0.41 | 0.46 | 0.76 | 1.19 |
65–74 | 0.24 | 0.31 | 0.46 | 0.55 |
75–84 | 0.21 | 0.22 | 0.36 | 0.48 |
85+ | 0.21 | 0.22 | 0.36 | 0.48 |
OA Progression Estimates (annual probability, %) | ||||
 | Male | Female | ||
Progression from K-L 2 to K-L 3 (non-obese/obese) | 5.58/ 12.26 | 4.00/ 8.95 | ||
Progression from K-L 3 to K-L 4 (non-obese/obese) | 1.29/ 2.94 | 1.95/ 4.27 | ||
Risk Factors (multipliers for increased OA incidence, derived from Zhang et al. [33]) | ||||
Knee injury | 2.39 | Â | Â | Â |
Family history of OA | 1.72 | Â | Â | Â |
Occupational risks | 1.28 | Â | Â | Â |