Rationale and design of The Delphi Trial – I(RCT)2: international randomized clinical trial of rheumatoid craniocervical treatment, an intervention-prognostic trial comparing 'early' surgery with conservative treatment [ISRCTN65076841]

Table 5 Primary outcome parameters: Events

Event
1. Neurological disability	Worsened MDI > 3 points Signs of myelopathy (Ranawat IIIA and IIIB)
2. Radiological progression	Signs of myelopathy on MRI Vertical translocation/Impression brainstem AADI > 12 mm
3. Surgery	Conservative treatment group - Intolerable pain
4. Resurgery	Surgical group
5. Death	All causes

ISSN: 1471-2474