Table 3 Univariate analyses of ferritin levels at entry after natural log (Ln) transformation according to diseases, age, sex, race, and genotype at entry
Variables | Continuous ferritin levels | Dichotomized ferritin levels | ||
|---|---|---|---|---|
Mean ± SD ng/ml | P value* | Odds ratio [95% CI] | P value** | |
OA patients ( N = 127) | 59.1 ± 114.9 | 0.334 | 2.21 [0.71–8.25] | 0.151 |
Healthy controls ( N = 20) | 37.07 ± 22.98 |  |  |  |
Age >56 years ( N = 109) ¶ | 62.5 ± 121.7 | 0.0186 | 2.31 [0.94– 6.15] | 0.050 |
Age ≤56 years ( N = 38) | 35.6 ± 22.8 |  |  |  |
Female ( N = 89) | 51.94 ± 133.5 | 0.0006 | 2.8 [1.34– 5.9] | 0.0034 |
Male ( N = 58) | 62.49 ± 43.7 |  |  |  |
White ( N = 97) | 57.7 ± 128.9 |  | 0.78 [0.37–1.7] | 0.595 |
Asian ( N = 13) | 48.52 ± 33.9 | 0.727 |  |  |
African American ( N = 37) | 54.4 ± 44.8 | 0.411 |  |  |
Genotype: | Â | Â | Â | Â |
  +/+ ( N = 110) | 47.4 ± 38.7 | Reference |  |  |
  H63D/+ ( N = 23) | 43.0 ± 37.1 | 0.529*** | 1.2 [0.44–3.38] | 0.646 |
  C282Y/+ ( N = 7) | 44.2 ± 34.8 | 0.951*** | 0.65 [0.06– 4.19] | 0.709 |
  H63D/H63D ( N = 2) | 21.3 ± 11.6 | 0.401*** |  | NA |
  C282Y/H63D ( N = 2) | 75.3 ± 6.6 | 0.210*** |  | NA |
  C282Y/C282Y ( N = 3) | 513.6 ± 646.9 | 0.00006*** |  | NA |