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Figure 3 | BMC Musculoskeletal Disorders

Figure 3

From: Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis

Figure 3

High prevalence of anti-gastric autoantibodies in the affected twins with myositis. Samples from 93 subjects were evaluated for autoantibodies against (A.) TPO, (B.) TGM2, (C.) gastric ATPase and (D.) IFN-α. The individual autoantibody levels are plotted on the Y-axis using a log10 scale and the median antibody value in each group is shown by the horizontal line. Only the statistically significant P values between the two groups are shown and were calculated using the Mann-Whitney U test. For these four autoantigens, pre-determined cut-off values along with the seropositive status were assigned before the sample codes were revealed.

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