Identification of initial severity determinants to predict arthritis after chikungunya infection in a cohort of French gendarmes

Table 1 Prognostic factors associated with rheumatic symptoms in 2008, cohort of French Gendarmes (2006–2008), n = 403 (Multinomial Logistic Regression Analysis)

	Multivariate analysis (without early chronic symptoms)		Multivariate analysis (with early chronic symptoms)
	Reference: no rheumatic disorders OR (95% CI)		Reference: no rheumatic disorders OR (95% CI)
	Arthralgia	Arthritis	Arthralgia	Arthritis
CHIKV Infection	4.67 (2.32-9.41)ǂ	26.75 (11.15-64.17)ǂ	2.58 (1.05-6.38)*	10.56 (3.42-32.63)ǂ
Comorbidity^a	2.00 (1.25-3.20)ǂ	2.47 (1.19-5.14)*	2.03 (1.26-3.27)ǂ	2.27 (1.06-4.87)*
Symptoms at acute stage
Depressed mood^b	8.90 (1.06-74.95)*	13.92 (1.66-116.88)*	-	-
Symptoms at early chronic stage (median: 6 months after infection)
Arthralgia^c	-	-	8.64 (1.95-38.17)ǂ	6.65 (1.33-33.30)*
Arthritis^d	-	-	2.93 (0.47-18.18)	19.38 (3.36-111.82)ǂ

*p < 0.05; ǂp < 0.005; OR: odds ratio; CI: confidence interval.
^aHistory of at least one of the following pathologies: sprain or dislocation of joints or bones and joint diseases, before CHIKV infection.
^bSelf-assessed mood coded as “depressed” if checked affected or totally depressed.
^cArthralgia = joint pain and/or stiffness.
^dArthritis = swelling in addition to joint pain and stiffness.

ISSN: 1471-2474