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Table 2 Coding of individual variables in the frailty index and their odds ratios of falls during the third year of follow-up

From: Frailty index of deficit accumulation and falls: data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) Hamilton cohort

Variables

Coding

Falls

OR (95% CI, P-value)a

n (%)b

Co-morbidities (n = 15)

Taking/taken five or more medicationsc

Yes = 1, no = 0

1.30 (1.07-1.59) 0.008

607 (15.23)

Has chronic bronchitis or emphysemac

Yes = 1, no = 0

1.40 (1.08-1.81) 0.012

307 (7.93)

Has osteoarthritis or degenerative joint diseasec

Yes = 1, no = 0

1.53 (1.32-1.78) <0.001

1,354 (35.05)

Has rheumatoid arthritisc

Yes = 1, no = 0

1.45 (1.16-1.81) <0.001

447 (11.57)

Suffers from strokec

Yes = 1, no = 0

2.16 (1.55-3.00) <0.001

193 (4.92)

Has ulcerative colitis or Crohn’s diseasec

Yes = 1, no = 0

2.08 (1.32-3.28) 0.002

82 (2.09)

Has celiac diseasec

Yes = 1, no = 0

1.20 (0.50-2.88) 0.683

25 (0.64)

Has Parkinson’s diseasec

Yes = 1, no = 0

3.09 (0.98-9.74) 0.054

18 (0.46)

Has multiple sclerosisc

Yes = 1, no = 0

1.28 (0.52-3.17) 0.596

22 (0.56)

Has cancerc

Yes = 1, no = 0

1.06 (0.86-1.32) 0.570

502 (12.77)

Has diabetes (type-1)c

Yes = 1, no = 0

1.44 (1.00-2.08) 0.053

165 (4.22)

Has hypertensionc

Yes = 1, no = 0

1.14 (0.99-1.32) 0.077

2,025 (51.63)

Has heart diseasec

Yes = 1, no = 0

1.52 (1.25-1.86) <0.001

623 (16.01)

Has high cholesterolc

Yes = 1, no = 0

1.15 (1.00-1.33) 0.050

1,752 (45.03)

Self rating of healthd

Excellent = 0, very good = 0.25, good = 0.5, fair = 0.75, poor = 1

2.77 (1.99-3.86) <0.001

73 (1.85)

Activities of daily living (ADL) (n = 12)

Limitations in vigorous activitiesc

Yes = 1, a little = 0.5, no = 0

1.67 (1.37-2.05) <0.001

1,735 (45.49)

Limitations in moderate activitiesd

Yes = 1, a little = 0.5, no = 0

2.04 (1.65-2.52) <0.001

569 (14.59)

Limitations in lifting or carrying groceriesd

Yes = 1, a little = 0.5, no = 0

2.01 (1.61-2.52) <0.001

416 (10.62)

Limitations in climbing one flight of stairsd

Yes = 1, a little = 0.5, no = 0

2.22 (1.76-2.80) <0.001

374 (9.69)

Limitations bending, kneeling or stoopingd

Yes = 1, a little = 0.5, no = 0

2.02 (1.66-2.46) <0.001

781 (20.12)

Limitations walking one hundred yardsd

Yes = 1, a little = 0.5, no = 0

1.97 (1.56-2.48) <0.001

378 (9.88)

Limitations in bathing or dressing yourselfd

Yes = 1, a little = 0.5, no = 0

1.88 (1.37-2.59) <0.001

154 (3.93)

Needs arms to help stand up from a chaird

Yes = 1, no = 0

1.83 (1.57-2.13) <0.001

1,495 (37.98)

Number of days to walk at least 20 minutes in the past 30 daysd

≤2 days = 1, >2 days = 0

1.21 (1.02-1.43) 0.025

1,081 (27.50)

Self rating of mobilityd

Unable = 1, some problem = 0.5, no problem = 0

3.05 (2.22-4.18) <0.001

1 (0.03)

Self rating of self-cared

Unable = 1, some problem = 0.5, no problem = 0

6.83 (3.75-12.43) <0.001

4 (0.10)

Self rating of usual activitiesd

Unable = 1, some problem = 0.5, no problem = 0

3.60 (2.68-4.84) <0.001

56 (1.41)

Symptoms and sig ns (n = 6)

Feels full of lifed

All the time = 0, most of time = 0.25, some time = 0.5, a little time = 0.75, none of time = 1

3.61 (2.66-4.89) <0.001

228 (5.84)

Has a lot of energyd

All the time = 0, most of time = 0.25, some time = 0.5, a little time = 0.75, none of time = 1

3.91 (2.88-5.31) <0.001

263 (6.73)

Feels worn outd

All the time = 1, most of time = 0.75, some time = 0.5, a little time = 0.25, none of time = 0

3.73 (2.73-5.09) <0.001

123 (3.15)

Feels tiredd

All the time = 1, most of time = 0.75, some time = 0.5, a little time = 0.25, none of time = 0

4.14 (2.98-5.76) <0.001

173 (4.40)

Self rating of pain/discomfortd

Extremely = 1, moderate = 0.5, no = 0

3.22 (2.43-4.28) <0.001

242 (6.15)

Unintentional weight loss of 10 poundsc

Yes = 1, no = 0

1.42 (1.12-1.80) 0.004

433 (11.01)

Healthcare utilization (n = 1)

Times of visiting a healthcare provider to get medical care in the past yearc

None = 0, 1–2 times = 0.33, 3–5 times = 0.67, 6 or more times = 1

1.39 (1.28-1.51) <0.001

842 (21.43)

  1. aOR: odds ratio, adjusted for baseline age; CI: confidence interval.
  2. bFor participants whose score was 1 in individual variable.
  3. cOrdinal logistic regression results, p-values of tests for the proportional odds assumption were >0.05.
  4. dBinary logistic regression since proportional odds assumption was not met.