SNP | Study 1 | Study 2 | Study 1 + Study 2 | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Case | Control | OR (95% CI)# | Case | Control | OR (95% CI)# | OR (95% CI)#$ | ORMeta | I2 | ||
rs3911238 | GG | 294 | 216 | 1 | 381 | 266 | 1 | 1 | 1 | |
GC | 99 | 89 | 0.84 (0.59-1.82) | 129 | 101 | 0.86 (0.63-1.18) | 0.84 (0.67-1.06) | 0.85 (0.67-1.08) | 0 | |
CC | 10 | 9 | 0.92 (0.36-2.40) | 15 | 12 | 0.92 (0.42-2.03) | 0.93 (0.51-1.72) | 0.92 (0.50-1.68) | 0 | |
G | 0.85 | 0.83 | 1 | 0.85 | 0.84 | 1 | 1 | 1 | ||
C | 0.15 | 0.17 | 0.87 (0.65-1.17) | 0.15 | 0.16 | 0.89 (0.69-1.16) | 0.88 (0.73-1.07) | 0.88 (0.73-1.07) | 0 | |
rs10174098 | AA | 285 | 209 | 1 | 351 | 240 | 1 | 1 | 1 | |
AG | 104 | 96 | 0.74 (0.52-1.04) | 154 | 129 | 0.77 (0.57-1.03) | 0.77 (0.62-0.96) | 0.76 (0.60-0.95) | 0 | |
GG | 14 | 9 | 1.27 (0.53-3.05) | 20 | 10 | 1.19 (0.53-2.64) | 1.22 (0.68-2.20) | 1.23 (0.68-2.22) | 0 | |
A | 0.84 | 0.82 | 1 | 0.82 | 0.80 | 1 | 1 | 1 | ||
G | 0.16 | 0.18 | 0.86 (0.65-1.14) | 0.18 | 0.20 | 0.87 (0.68-1.11) | 0.88 (0.73-1.05) | 0.87 (0.72-1.04) | 0 | |
rs3738919 | CC | 366 | 273 | 1 | 468 | 344 | 1 | 1 | 1 | |
CA | 35 | 37 | 0.66 (0.39-1.09) | 54 | 44 | 0.87 (0.56-1.34) | 0.77 (0.55-1.06) | 0.78 (0.55-1.09) | 0 | |
AA | 2 | 4 | 0.29 (0.05-1.70) | 3 | 1 | 2.18 (0.22-21.58) | 0.70 (0.19-2.50) | 0.69 (0.10-4.90) | 46.58 | |
C | 0.95 | 0.93 | 1 | 0.94 | 0.94 | 1 | 1 | 1 | ||
A | 0.05 | 0.07 | 0.60 (0.38-0.95) | 0.06 | 0.06 | 0.93 (0.62-1.40) | 0.77 (0.57-1.04) | 0.76 (0.49-1.16) | 49.44 | |
rs1448427 | AA | 267 | 196 | 1 | 325 | 234 | 1 | 1 | 1 | |
AG | 123 | 108 | 0.90 (0.37-2.18) | 179 | 129 | 1.00 (0.49-2.03) | 0.91 (0.74-1.13) | 0.96 (0.55-1.67) | 0 | |
GG | 13 | 10 | 0.79 (0.57-1.10) | 21 | 16 | 1.00 (0.75-1.34) | 0.96 (0.55-1.66) | 0.90 (0.72-1.13) | 11.32 | |
A | 0.82 | 0.80 | 1 | 0.79 | 0.79 | 1 | 1 | 1 | ||
G | 0.18 | 0.20 | 0.85 (0.65-1.12) | 0.21 | 0.21 | 1.00 (0.79-1.27) | 0.94 (0.79-1.12) | 0.93 (0.78-1.11) | 0 |