| Model 1aRR (95% CI) | Model 2aRR (95% CI) | Model 3bRR (95% CI) | Model 4bRR (95% CI) |
---|---|---|---|---|
Risk factor | Â | Â | Â | Â |
Male sex | 1.73 (1.36, 2.21) | 1.10 (0.85, 1.43) | 1.02 (0.80, 1.31) | 1.54 (1.21, 1.97) |
African American race | 1.79 (1.37, 2.33) | 1.68 (1.29, 2.18) | 1.50 (1.15, 1.94) | 1.64 (1.26, 2.13) |
<High school education | 1.27 (0.99, 1.63) | 1.29 (1.00, 1.65) | 1.15 (0.89, 1.49) | 1.23 (0.96, 1.58) |
Hypertension | 1.65 (1.3, 2.09) | 1.47 (1.15, 1.87) | 1.27 (0.99, 1.62) | 1.44 (1.12, 1.84) |
Coronary heart disease | 1.57 (0.99, 2.50) | 1.60 (1.00, 2.56) | 1.48 (0.90, 2.43) | 1.45 (0.89, 2.37) |
Smoking status | Â | Â | Â | Â |
Current smoker | 1.27 (0.97, 1.67) | 1.29 (0.98, 1.69) | 1.26 (0.96, 1.66) | 1.27 (0.96, 1.66) |
Former smoker | 0.84 (0.64, 1.11) | 0.81 (0.62, 1.07) | 0.78 (0.60, 1.03) | 0.83 (0.63, 1.09) |
Never smoker | Reference | Reference | Reference | Reference |
Body mass index, kg/m 2 | Â | Â | Â | Â |
BMI ≥  35 | 3.47 (2.33, 5.18) | 2.07 (1.37, 3.14) | 2.18 (1.44, 3.31) | 3.25 (2.16, 4.9) |
30 ≤  BMI < 35 | 2.37 (1.65, 3.41) | 1.76 (1.22, 2.54) | 1.90 (1.31, 2.75) | 2.37 (1.64, 3.40) |
25 ≤  BMI < 30 | 2.01 (1.46, 2.78) | 1.64 (1.19, 2.26) | 1.79 (1.30, 2.46) | 2.04 (1.48, 2.81) |
BMI < 25 | Reference | Reference | Reference | Reference |
eGFR, ml/min/1.73Â m 2 | Â | Â | Â | Â |
<60 | 2.85 (1.62, 5.01) | 1.97 (1.12, 3.47) | 2.05 (1.24, 3.39) | 2.86 (1.70, 4.82) |
60-90 | 1.12 (0.89, 1.42) | 0.95 (0.75, 1.20) | 1.05 (0.84, 1.32) | 1.18 (0.94, 1.48) |
≥ 90 | Reference | Reference | Reference | Reference |
Triglyceride, mg/dL | Â | Â | Â | Â |
Quartile 4: ≥ 157 | 2.00 (1.38, 2.89) | 1.48 (1.03, 2.13) | 1.44 (1.01, 2.04) | 1.93 (1.35, 2.76) |
Quartile 3: 110 -156 | 1.46 (1.01, 2.12) | 1.20 (0.83, 1.73) | 1.12 (0.79, 1.60) | 1.41 (0.99, 2.02) |
Quartile 2: 79 - 109 | 1.08 (0.73, 1.60) | 0.96 (0.65, 1.41) | 1.00 (0.68, 1.46) | 1.12 (0.76, 1.65) |
Quartile 1: ≤  78 | Reference | Reference | Reference | Reference |
Serum Urate Level at Visit1, mg/dL | Â | 2.33 (1.94, 2.80) | Â | Â |
Serum Urate Level at Visit2, mg/dL | Â | Â | 1.92 (1.78, 2.07) | Â |
Change in serum urate level (Visit 2-Visit 1), mg/dL | Â | Â | Â | 1.60 (1.47, 1.74) |