The association of body-mass index and depressed mood with knee pain and activity limitations in knee osteoarthritis: results from the Amsterdam osteoarthritis cohort

Table 4 Association of BMI and depressed mood with performance-based activity limitations

Analysis	Independent variables	B (95% CI)	β	p	Semi-partial r²× 100%
1.	BMI	0.42 (0.33, 0.51)	0.47	<0.001	21.9%
2.	HADS depression	0.31 (0.14, 0.48)	0.21	0.001	4.0%
3.	BMI	0.40 (0.31, 0.49)	0.45	<0.001	19.0%
3.	HADS depression	0.17 (0.01, 0.32)	0.11	0.038	1.1%
	Dominance analysis
	Overall average BMI	(0.219 + 0.190)/2 = 0.204			20.4%
	Overall average HADS depression	(0.040 + 0.011)/2 = 0.026			2.6%

Performance-based activity limitations were assessed with a get up and go test. In all analyses we adjusted for age, gender, marital status, education level, radiographic OA and comorbidity. B (95% CI), Regression coefficient ( 95% confidence interval). β, Standardized regression coefficient. Semi-partial r ², Squared semi-partial correlation coefficient. BMI, Body-mass index. HADS, Hospital Anxiety and Depression Scale.

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