Changes in trabecular bone microarchitecture in postmenopausal women with and without type 2 diabetes: a two year longitudinal study

Table 2 Unadjusted trabecular bone microarchitecture measures for participants with valid MRI images who completed both baseline and follow-up assessments

	Women with type 2 diabetes			Controls
	Baseline n= 14	Follow-up n= 14	Absolute change from baseline	Baseline n= 21	Follow-up n= 21	Absolute change from baseline	Between group difference *p-value*
Hole size, mm²	2.10 (0.47)	2.04 (0.37)	−0.06 (0.48)	2.06 (0.42)	2.08 (0.45)	0.03 (0.32)	0.513
Number of holes	68 (17)	69 (13)	1 (15)	72 (15)	68 (18)	−4 (12)	0.283
Endosteal area, mm²	260.7 (51.1)	264.8 (56.9)	4.0 (39.9)	273.2 (58.4)	258.3 (48.9)	−14.9 (39.6)	0.939
BVTV, %	47.7 (1.0)	47.9 (0.8)	0.2 (0.9)	47.7 (1.2)	47.8 (1.0)	0.1 (0.7)	0.759
Tb.Th, mm	0.52 (0.01)	0.51 (0.01)	0 (0.01)	0.51 (0.01)	0.51 (0.01)	0 (0.01)	0.549
Tb.Sp, mm	0.55 (0.01)	0.54 (0.01)	0 (0.01)	0.54 (0.02)	0.54 (0.02)	0 (0.01)	0.322
Tb.N,/mm	0.92 (0.03)	0.93 (0.02)	0.01 (0.02)	0.93 (0.03)	0.93 (0.03)	0 (0.01)	0.362
Nodal density, /mm²	0.16 (0.01)	0.16 (0.01)	0 (0.01)	0.16 (0.01)	0.15 (0.01)	0 (0.01)	0.574
Branch density, /mm²	0.41 (0.06)	0.42 (0.05)	0.01 (0.05)	0.41 (0.05)	0.42 (0.06)	0.01 (0.05)	0.940

Values are mean (SD). Between group difference for absolute change in trabecular bone microarchitecture measures for women with and without type 2 diabetes.
Abbreviations: BVTV, bone volume fraction; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; Tb.N, trabecular number.

ISSN: 1471-2474