| IL18RAP(rs1420106) | IL18RAP(rs917997) | MMP3(rs72520913) | ||||||
---|---|---|---|---|---|---|---|---|---|
Genotype | A/A | A/G | G/G | T/T | C/T | C/C | A/A | A/C | C/C |
Number of Patients | 7 | 33 | 53 | 7 | 36 | 50 | 18 | 56 | 19 |
Males / Females | 2/5 | 10/23 | 23/30 | 2/5 | 11/25 | 22/28 | 8/10 | 19/37 | 8/11 |
Age at follow-up | 49.9 [9.1] | 49.3 [12.9] | 53.8 [7.3] | 49.9 [9.1] | 49.8 [8.2] | 53.7 [7.4] | 51.6 [8.7] | 53.2 [6.7] | 48.4 [10.0] |
Mean [SD] | |||||||||
Fusion/cognitive | 5/2 | 23/10 | 32/21 | 5/2 | 24/12 | 31/19 | 10/8 | 39/17 | 11/8 |
Baseline ODI | 43.1 [8.9] | 47.6 [12.9] | 42.0 [9.6] | 43.1 [8.9] | 46.5 [18.2] | 42.5 [9.6] | 40.3 [10.0] | 45.1 [11.0] | 44.6 [11.8] |
Mean [SD] | |||||||||
Follow-up ODI | 41.1 [20.6] | 23.9 [18.5] | 21.9 [17.6] | 41.1 [20.6] | 25.1 [18.2] | 21.0 [17.6] | 25.2 [14.1] | 24.6 [19.6] | 21.3 [19.8] |
Mean [SD] | |||||||||
ODI change | - 2 [17.8] | - 23.8 [20.8] | - 20.0 [20.8] | - 2 [17.8] | - 21.4 [21.5] | - 21.5 [19.6] | - 15.2 [16.3] | - 20.4 [22.0] | - 23.3 [20.8] |
Mean [SD] | |||||||||
Baseline VAS LBP | 56.5 [14.2] | 64.5 [13.3] | 61.9 [13.7] | 56.5 [14.2] | 63.7 [13.1] | 62.3 [14.0] | 59.5 [11.7] | 62.5 [13.5] | 64.7 [15.9] |
Mean [SD] | |||||||||
Follow-up VAS LBP | 48.8 [23.2] | 38.4 [25.3] | 36.0 [25.8] | 48.8 [23.2] | 39.1 [24.5] | 35.3 [26.3] | 48.7 [20.0] | 33.8 [25.6] | 39.2 [27.5] |
Mean [SD] | |||||||||
VAS LBP change | - 7.7 [24.3] | - 26.1 [25.8] | - 25.9 [32.9] | - 7.7 [24.3] | - 24.6 [25.3] | - 27.0 [33.5] | - 10.8 [18.5] | - 28.7 [33.2] | - 25.5 [26.2] |
Mean [SD] |