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Table 1 Overview of the selected SNPs and their genotyping performance

From: Treatment outcome of chronic low back pain and radiographic lumbar disc degeneration are associated with inflammatory and matrix degrading gene variants: a prospective genetic association study

SNP*

Gene

HWE** p-value

GRS %†

Alleles‡

MAF§ cases

MAF ∞ reported

rs2071375

IL1A

1.0

100

T/C

0.25

0.21

rs2287037

IL18R1

0.73

100

T/C

0.32

0.39

rs1420100

IL18RAP

1.0

100

A/C

0.50

0.51

rs1420106

IL18RAP

0.7

100

A/G

0.25

0.21

rs917997

IL18RAP

1.0

100

T/C

0.27

0.20

rs5277

COX2

0.81

100

G/C

0.19

0.21

rs4140564

COX2

1.0

100

G/A

0.05

0.08

rs72520913

MMP3

0.09

100

A/C

0.50

Not reported

  1. * Single nucleotide polymorphism; ** Hardy-Weinberg equilibrium; † Genotype success rate;
  2. ‡ Minor/Major alleles; § Minor allele frequency; ∞ MAF HapMap-CEU European.
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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