Effect of leisure time physical activity on severe knee or hip osteoarthritis leading to total joint replacement: a population-based prospective cohort study

Table 3 Incidence of hip replacement (THR) due to osteoarthritis in relation to leisure time physical activity

Physical activity leisure, baseline	Cases, n	RR (95% CI)*	P, trend	RR (95% CI)†	P, trend	RR (95% CI) ‡	P, trend
THR
*All*
Low (n = 6935)	150	1.0	0.159	1.0	0.045	1.0	0.192
Low-moderate (n = 6933)	144	0.94 (0.75, 1.18)		0.93 (0.74, 1.17)		0.97 (0.77, 1.23)
Moderate-high (n = 6957)	134	0.87 (0.69, 1.10)		0.85 (0.68, 1.08)		0.91 (0.72, 1.16)
High (n = 6935)	129	0.86 (0.68, 1.09)		0.80 (0.63, 1.01)		0.86 (0.68, 1.10)
*Men*
Low (n = 2777)	38	1.0	0.081	1.0	0.332	1.0	0.187
Low-moderate (n = 2634)	49	1.33 (0.87, 2.03)		1.28 (0.84, 1.95)		1.31 (0.86, 2.01)
Moderate-high (n = 2598)	43	1.18 (0.76, 1.83)		1.09 (0.71, 1.69)		1.15 (0.74, 1.79)
High (n = 2914)	60	1.51 (1.01, 2.27)		1.31 (0.87, 1.97)		1.40 (0.93, 2.12)
*Women*
Low (n = 4158)	112	1.0	0.003	1.0	0.002	1.0	0.008
Low-moderate (n = 4299)	95	0.81 (0.61, 1.06)		0.82 (0.62, 1.07)		0.85 (0.64, 1.12)
Moderate-high (n = 4359)	91	0.76 (0.58, 1.01)		0.78 (0.59, 1.02)		0.82 (0.62, 1.09)
High (n = 4021)	69	0.63 (0.47, 0.85)		0.62 (0.46, 0.83)		0.66 (0.48, 0.89)

Incidence of hip replacement due to osteoarthritis during a mean follow-up of 11 years, in relation to leisure time physical activity at baseline (low (Q1), low–moderate (Q2), moderate–high (Q3), and high physical activity (Q4)).
*crude, † adjusted for age, gender, ‡ adjusted for age, gender (for all subjects only), BMI, education, smoking, marital status.

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