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Table 2 DXR-MCI loss in the methotrexate plus adalimumab group and the MTX group stratified for disease activity measured by DAS28

From: Adalimumab reduces hand bone loss in rheumatoid arthritis independent of clinical response: Subanalysis of the PREMIER study

 

Adalimumab + methotrexate

Methotrexate

 

N = 214

Median (mean) % DXR-MCI change

N = 188

Median (mean) % DXR-MCI change

Remission

DAS28 ≤2.60

118

-2.43 (-2.73)

53

-2.15 (-3.03)

Low

disease activity

DAS28 2.61-3.20

36

-1.98 (-2.59)

30

-2.09 (-2.90)

Moderate

disease activity

DAS 28 3.21-5.10

51

-2.01 (-3.17)

81

-3.33 (-4.65)

High

disease activity

DAS28> 5.10

9

-1.63 (-2.72)

24

-3.02 (-4.64)

  1. DAS28 = 28-joint disease activity score; DXR = Digital X-ray radiogrammetry; MCI = metacarpal cortical index