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Table 1 Red flag conditions indicating possible underlying spinal pathology or nerve root problems that will be recorded.

From: Back Complaints in the Elders (BACE); design of cohort studies in primary care: an international consortium

Red flag

Possible underlying pathology

Previous history of cancer

Cancer

Age at unset < 20 or > 55 years

Cancer

Unexplained weight loss

Cancer

Pain at rest

Cancer

Non-mechanical pain

Cancer, vertebral infection

Systematically unwell

Cancer, vertebral infection

Increased C-reactive protein level

Cancer, vertebral infection

Fever

Vertebral infection

Urine tract infection or skin infection

Vertebral infection

Recent bacterial infection e.g. urinary tract or skin infection

Vertebral infection

Age > 70 years

Fracture

Trauma as cause of the back complaint

Fracture

Sudden decrease in height

Fracture

History of osteoporosis

Fracture

Urinary retention

Cauda equina syndrome

Acute onset of urinary retention or incontinence

Cauda equina syndrome

Morning stiffness

Inflammatory disorder

Pain improves with physical activity

Inflammatory disorder

Pain in the leg worse than back pain

Lumbosacral radicular syndrome