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Table 7 Haplotype frequencies of PAI-1 gene polymorphisms between ONFH patients (n = 206) and controls (n = 251)

From: Significant associations of PAI-1 genetic polymorphisms with osteonecrosis of the femoral head

 

Haplotype

Frequency

  
 

rs2227631

rs1799889

rs11178

Controls

Patients

OR (95% CI)

p

Hap1a

G

5G

T

0.391

0.310

1*

-

Hap2

A

4G

C

0.305

0.398

1.63(1.31-2.02)

<0.001

Hap3

G

4G

C

0.113

0.103

1.14(0.83-1.55)

0.425

Hap4

G

4G

T

0.115

0.092

0.98(0.71-1.34)

0.875

  1. aHaplotype G-5G-T (Hap1) was chosen to be the baseline haplotype; *reference category (odds ratio, 1.0)