Figure 4From: Silencing Dkk1 expression rescues dexamethasone-induced suppression of primary human osteoblast differentiation In order to validate these findings, cells transfected with pBAR were treated with Wnt 3a conditioned media (Wnt agonist) and L-cell conditioned media (control). Significant reductions in luciferase activity were identified when 10-8 M dexamethasone was added to both conditioned media over a 48 hr time course. *p < 0.05, ***p < 0.001 versus control.Back to article page