Treatment Group | Total Osteoclast Numbers | Articular cartilage area without proteoglycan staining (%) | Damaged articular cartilage surface (%) | Thickness of total articular cartilage area (μM) |
---|---|---|---|---|
Vehicle Control | 33.9 | 17.23 | 47.3 | 26.06 |
2ME2 100 mg/kg | 0 | 0.18* | 0* | 32.64* |
2ME2 10 mg/kg | 5.7* | 6.71 | 27.9 | 27.34 |
2ME2 1 mg/kg | 21.9* | 11.21 | 37.0 | 27.5 |