Figure 8From: Disease modifying and antiangiogenic activity of 2-Methoxyestradiol in a murine model of rheumatoid arthritis Effect of 2ME2 on Expression of Angiogenic and Inflammatory Cytokines. Total RNA from mouse hind limbs on study day 14 was isolated and gene expression of inflammatory (IL-6, IL-1b, TNF-a, IL-17) and angiogenic cytokines (VEGF, FGF-2) was assessed. Expression of all molecules evaluated were down-modulated upon treatment with 2ME2.Back to article page