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Osteoarthritis - from basic and translational approaches to clinical practice

Guest Editor: Professor Ali Mobasheri (University of Surrey, UK)

Osteoarthritis (OA) is the most common form of arthritis and is characterised by damage or breakdown of articular cartilage in load-bearing joints, particularly in the knees, hips and hands. The disorder is one of the leading causes of disability worldwide and results in pain, stiffness, joint deformity and loss of joint mobility, which often develop slowly over time. There are a number of risk factors associated with OA, including age, obesity, metabolic disease, previous joint injury, abnormal joint loading and biomechanics, genetics and systemic inflammation. However, OA predominantly affects older people, often co-existing with other comorbid conditions associated with aging.

We are welcoming Research articles, Case reports, Debates and Reviews on all aspects of research into OA covering the cellular, molecular and genetic mechanisms underlying the disease through to clinical investigations describing the effects of the disease on target joints, including pain and stiffness, and associated lifestyle and risk factors. Studies describing the epidemiology of OA are also welcomed. Please note that the primary focus of any submitted papers should relate specifically to a component(s) of the musculoskeletal system, in this case OA.

To submit your manuscript, please use our online submission system at BMC Musculoskeletal Disorders. Please indicate in your cover letter that you would like the article to be considered for the ‘Osteoarthritis - from translational approaches to clinical practice’ special series.

If you would like to inquire about the suitability of a study for consideration, please email a presubmission enquiry to bmcmusculoskeletdisord@biomedcentral.com.

Deadline for submission: 1 December 2018