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  1. Female patients are more likely to have tendon injuries than males, especially those who has a higher concentration of relaxin. Previous studies have demonstrated that relaxin attenuates extracellular matrix (...

    Authors: Tianpeng Xu, Jiaxiang Bai, Menglei Xu, Binqing Yu, Jiayi Lin, Xiaobin Guo, Yu Liu, Di Zhang, Kai Yan, Dan Hu, Yuefeng Hao and Dechun Geng
    Citation: BMC Musculoskeletal Disorders 2019 20:349
  2. Heterotopic ossification (HO) is a relatively common complication following hip surgery treated with open reduction and internal fixation, total arthroplasty or hemiarthroplasty. Development of HO after hip su...

    Authors: Daichi Hayashi, Elaine S. Gould, Corey Ho, Dennis L. Caruana, David E. Komatsu, Jie Yang, Chencan Zhu, Musa Mufti and James Nicholson
    Citation: BMC Musculoskeletal Disorders 2019 20:348
  3. Impaired lumbar artery flow has been reported in clinical and epidemiological studies to be associated with low back pain and lumbar disc degeneration. However, it has not been experimentally demonstrated that...

    Authors: Takao Imanishi, Koji Akeda, Koichiro Murata and Akihiro Sudo
    Citation: BMC Musculoskeletal Disorders 2019 20:347
  4. The aims of this study were to discuss the principle, therapeutic effect and influencing factors of multiple wrapped cancellous bone graft methods for treatment of segmental bone defects.

    Authors: Yunhong Ma, Sanjun Gu, Qudong Yin, Haifeng Li, Yongwei Wu, Zihong Zhou, Dehong Feng and Yongjun Rui
    Citation: BMC Musculoskeletal Disorders 2019 20:346
  5. Superior shoulder dislocation is a rare type of shoulder dislocation. Its occurrence is thought to be associated with rupture of the deltoid; however, few reports are available on the mechanism of onset and th...

    Authors: Ryogo Furuhata, Yasuhiro Kiyota, Taiki Ikeda, Masaaki Takahashi, Hideo Morioka and Hiroshi Arino
    Citation: BMC Musculoskeletal Disorders 2019 20:345
  6. Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, w...

    Authors: Katherine A. Staines, Ekele Ikpegbu, Anna E. Törnqvist, Scott Dillon, Behzad Javaheri, Anish K. Amin, Dylan N. Clements, David J. Buttle, Andrew A. Pitsillides and Colin Farquharson
    Citation: BMC Musculoskeletal Disorders 2019 20:344
  7. Surgical treatment of radial head fractures is increasingly performed arthroscopically. These fractures often feature concomitant injuries to the elbow joint, which may be under-diagnosed in the radiological e...

    Authors: Florian Haasters, Tobias Helfen, Wolfgang Böcker, Hermann O. Mayr, Wolf Christian Prall and Andreas Lenich
    Citation: BMC Musculoskeletal Disorders 2019 20:343
  8. Knee osteoarthritis (OA) is a prevalent and chronic condition with no known cure. Exercise is advocated in all clinical guidelines due to its positive effects on symptoms. Despite this, exercise participation ...

    Authors: Rachel K. Nelligan, Rana S. Hinman, Jessica Kasza and Kim L. Bennell
    Citation: BMC Musculoskeletal Disorders 2019 20:342
  9. Tranexamic acid (TXA) is effective in reduction of hemorrhage after major surgical procedures. In total joint replacement it is commonly administered intravenously. Despite various studies regarding the safety...

    Authors: Eric Tille, Jonas Mysliwietz, Franziska Beyer, Anne Postler and Jörg Lützner
    Citation: BMC Musculoskeletal Disorders 2019 20:341
  10. To compare the efficacy and safety of simultaneous vs staged unicompartmental knee arthroplasty (UKA) for bilateral unicompartmental osteoarthritis of the knee.

    Authors: Shuo Feng, Zhi Yang, Jian-Ning Sun, Liang Zhu, Song Wang, Kai-Jin Guo, Xiang-Yang Chen and Guo-Chun Zha
    Citation: BMC Musculoskeletal Disorders 2019 20:340
  11. Local antibiotic application has been widely used in orthopedic surgery. The dose-related toxicity of antibiotics towards periosteal tissues and resulting effects on osteogenic expression are yet to be studied.

    Authors: Chih-Hao Chiu, Kin Fong Lei, Yi-Sheng Chan, Steve W. N. Ueng and Alvin Chao-Yu Chen
    Citation: BMC Musculoskeletal Disorders 2019 20:339
  12. The mechanism of pain after meniscus injury remains unknown. After injury, some individuals suffered from acute pain, while others suffer from delayed pain. A precise nociceptor distribution pattern may provid...

    Authors: Yipeng Lin, Kaibo Zhang, Qi Li, Jian Li and Bin Xu
    Citation: BMC Musculoskeletal Disorders 2019 20:338
  13. The objectives of this study were to estimate the population prevalence and distribution of plantar heel pain in mid-to-older age groups, examine associations with selected health status and lifestyle factors,...

    Authors: Martin J. Thomas, Rebecca Whittle, Hylton B. Menz, Trishna Rathod-Mistry, Michelle Marshall and Edward Roddy
    Citation: BMC Musculoskeletal Disorders 2019 20:337
  14. The endplate-intervertebral disc (IVD) complex is closely interrelated with the vertebral body (VB) in the structural integrity of the anterior spinal column, including biomechanical and biological functions. ...

    Authors: Tatsuhiko Fujiwara, Koji Akeda, Junichi Yamada, Tetsushi Kondo and Akihiro Sudo
    Citation: BMC Musculoskeletal Disorders 2019 20:336
  15. Previous basic research and clinical studies examined the effects of mesenchymal stem cells (MSCs) on regeneration and maintenance of articular cartilage. However, our pilot study suggested that MSCs are more ...

    Authors: Takumi Sakamoto, Tsuyoshi Miyazaki, Shuji Watanabe, Ai Takahashi, Kazuya Honjoh, Hideaki Nakajima, Hisashi Oki, Yasuo Kokubo and Akihiko Matsumine
    Citation: BMC Musculoskeletal Disorders 2019 20:335
  16. Biodegradable implants reduce the likelihood of further surgery for hardware removal and reduce the risks of associated infection and allergy. The purpose of this study is to evaluate the clinical efficacy and...

    Authors: Henry Dushan Atkinson, Shahnawaz Khan, Yasha Lashgari and Andreas Ziegler
    Citation: BMC Musculoskeletal Disorders 2019 20:334
  17. Intraosseous suture-button devices have been used for acromioclavicular joint reconstruction due to its relative simplicity compared with other procedures. However, the complications of acromioclavicular joint...

    Authors: Doji Inoue, Ryogo Furuhata, Kazuya Kaneda, Yoshihiro Ritsuno, Aki Kono, Yasuhiro Kiyota, Hideo Morioka and Hiroshi Arino
    Citation: BMC Musculoskeletal Disorders 2019 20:333
  18. Head breakage is a serious complication following total hip arthroplasty when using Ceramic on Ceramic bearings surfaces. There is still in controversy about the selection of bearing surfaces when conducting r...

    Authors: Dan Xing, Chaolei Yang, Rujun Li, Yunfei Hou, Bolong Kou, Hu Li and Jianhao Lin
    Citation: BMC Musculoskeletal Disorders 2019 20:332
  19. Although surgery prevents the progression of deformity and maintains the overall balance of the spine in congenital scoliosis (CS) patients, it is associated with a high risk of perioperative complications. Pu...

    Authors: Lei Wu, Xi-nuo Zhang, Yun-sheng Wang, Yu-zeng Liu and Yong Hai
    Citation: BMC Musculoskeletal Disorders 2019 20:331
  20. The aetiology of bone marrow oedema-like abnormalities (BMOA) seen on magnetic resonance imaging (MRI) is as yet not fully understood. The current study aimed to investigate the potential of projection radiogr...

    Authors: Christine J. Heales, Ian R. Summers, Jonathan Fulford, Karen M. Knapp and C. Peter Winlove
    Citation: BMC Musculoskeletal Disorders 2019 20:330
  21. In Swedish primary care, the healthcare process for patients with knee osteoarthritis (KOA) can be initiated by a physician or physiotherapist assessment. However, it is unclear how the different assessments a...

    Authors: Chan-Mei Ho, Carina A. Thorstensson and Lena Nordeman
    Citation: BMC Musculoskeletal Disorders 2019 20:329
  22. Low back pain (LBP) is common among healthcare workers, whose work is physically strenuous and thus demands certain levels of physical fitness and spinal control. Exercise is the most frequently recommended tr...

    Authors: Annika Taulaniemi, Markku Kankaanpää, Kari Tokola, Jari Parkkari and Jaana H. Suni
    Citation: BMC Musculoskeletal Disorders 2019 20:328
  23. This study was conducted to determine gender differences in the relationship between extracurricular sports activities (ECSA) and low back pain (LBP) in children and adolescents.

    Authors: Ren Kikuchi, Toru Hirano, Kei Watanabe, Atsuki Sano, Tsuyoshi Sato, Takui Ito, Naoto Endo and Naohito Tanabe
    Citation: BMC Musculoskeletal Disorders 2019 20:327
  24. Oestrogen-deficiency induced by menopause is associated with reduced bone density and primary osteoporosis, resulting in an increased risk of fracture. While the exact etiology of menopause-induced primary ost...

    Authors: Fraser L. Collins, Michael D. Stone, Jane Turton, Laura R. McCabe, Eddie C. Y. Wang and Anwen S. Williams
    Citation: BMC Musculoskeletal Disorders 2019 20:326
  25. The purpose of the study was to evaluate whether tranexamic acid (TXA) administration could reduce blood loss and transfusion risk after simultaneous bilateral total knee arthroplasty (SBTKA).

    Authors: Guorui Cao, Guo Chen, Qiang Huang, Zeyu Huang, Peter G. Alexander, Hang Lin, Hong Xu, Zongke Zhou and Fuxing Pei
    Citation: BMC Musculoskeletal Disorders 2019 20:325
  26. Osteoarthritis is the most common form of arthritis, principally affecting the older population. Highly prevalent, disabling diseases such as osteoarthritis strain the capacity of health systems, and can resul...

    Authors: J. Haxby Abbott, Aimee L. Ward, Chris Crane, Catherine M. Chapple, Kirsten Stout, Liam Hutton, Virginia Martin, Helen Harcombe, Daniel Cury Ribeiro and David Gwynne Jones
    Citation: BMC Musculoskeletal Disorders 2019 20:324
  27. Recurrent severe Dupuytren contracture of the small finger’s proximal interphalangeal (PIP) joint is a difficult problem. Further surgery carries high risk of complications and poor outcome. Patients are often...

    Authors: Asa Eiriksdottir and Isam Atroshi
    Citation: BMC Musculoskeletal Disorders 2019 20:323
  28. This study aimed to evaluate the association of body composition components and obesity with bone density.

    Authors: Isabel Oliveira Bierhals, Juliana dos Santos Vaz, Renata Moraes Bielemann, Christian Loret de Mola, Fernando Celso Barros, Helen Gonçalves, Fernando César Wehrmeister and Maria Cecília Formoso Assunção
    Citation: BMC Musculoskeletal Disorders 2019 20:322
  29. Pretension of the viscoelastic graft by cyclic knee motion has been confirmed to decrease the graft creep and improve the outcome of anterior cruciate ligament (ACL) reconstruction. The purpose of the present ...

    Authors: Dong Jiang, Ying-fang Ao, Chen Jiao, Qin-wei Guo, Xing Xie, Feng Zhao, Nan Li, Xiao-xiao Wang and Yue-lin Hu
    Citation: BMC Musculoskeletal Disorders 2019 20:321
  30. Muscle strength measurements using hand-held dynamometry (HHD) can be affected by the inadequate strength of the tester and lack of stabilization of the participants and the device. A portable HHD anchoring sy...

    Authors: Kwan-Sik Sung, You Gyoung Yi and Hyung-Ik Shin
    Citation: BMC Musculoskeletal Disorders 2019 20:320
  31. The Cobb angle is proposed as the “disease process” outcome for scoliosis research because therapies aim to correct or stop curve progression. While the Scoliosis Research Society recommends the Cobb angle as ...

    Authors: Sanja Schreiber, Eric C. Parent, Doug L. Hill, Douglas M. Hedden, Marc J. Moreau and Sarah C. Southon
    Citation: BMC Musculoskeletal Disorders 2019 20:319
  32. Surgical treatment of young patients with recurrent lateral patella dislocation (RLDP) is often recommended because of loss of knee function that compromises their level of activity or even their daily life fu...

    Authors: Truls Martin Straume-Næsheim, Per-Henrik Randsborg, Jan Rune Mikaelsen, Einar Andreas Sivertsen, Brian Devitt, Lars-Petter Granan and Asbjørn Årøen
    Citation: BMC Musculoskeletal Disorders 2019 20:318
  33. Radiological assessments are considered an important part of the management of patellar instability (PI). However, PI measurements are influenced by the knee position, which cannot be guaranteed to be the same...

    Authors: Qin Ye, Taihen Yu, Yinbo Wu, Xiaonan Ding and Xiangyang Gong
    Citation: BMC Musculoskeletal Disorders 2019 20:317
  34. Synovial mesenchymal stem cells (MSCs) are an attractive cell source for cartilage and meniscus regeneration. The optimum cryopreservation medium has not been determined, but dimethylsulfoxide (DMSO) should be...

    Authors: Ryota Fujisawa, Mitsuru Mizuno, Hisako Katano, Koji Otabe, Nobutake Ozeki, Kunikazu Tsuji, Hideyuki Koga and Ichiro Sekiya
    Citation: BMC Musculoskeletal Disorders 2019 20:316
  35. The incidence of proximal humeral fractures (PHF) increased by more than 30% over the last decade, which is accompanied by an increased number of operations. However, the evidence on operative vs. non-operativ...

    Authors: Corinna Nerz, Lars Schwickert, Sabine Schölch, Katharina Gordt, Philip-Christian Nolte, Inga Kröger, Peter Augat and Clemens Becker
    Citation: BMC Musculoskeletal Disorders 2019 20:315
  36. Female patients with systemic lupus erythematosus (SLE) are prone to have musculoskeletal system involvement, which could lead to joint damage. However, few studies have assessed the incidence of arthroplasty ...

    Authors: Chien-Han Chen, Chia-Wen Hsu and Ming-Chi Lu
    Citation: BMC Musculoskeletal Disorders 2019 20:314
  37. Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence o...

    Authors: Kika Konstantinou, Kate M. Dunn, Danielle van der Windt, Reuben Ogollah, Vinay Jasani and Nadine E. Foster
    Citation: BMC Musculoskeletal Disorders 2019 20:313
  38. People who have had anterior cruciate ligament reconstruction (ACLR) are at a high risk of developing tibiofemoral joint (TFJ) osteoarthritis (OA), with concomitant meniscal injury elevating this risk. This st...

    Authors: Xinyang Wang, Kim L. Bennell, Yuanyuan Wang, Tim V. Wrigley, Ans Van Ginckel, Karine Fortin, David J. Saxby, Flavia M. Cicuttini, David G. Lloyd, Christopher J. Vertullo, Julian A. Feller, Tim Whitehead, Price Gallie and Adam L. Bryant
    Citation: BMC Musculoskeletal Disorders 2019 20:312
  39. The treatment of open tibial shaft fractures is challenging. External fixation (EF) is comparatively safe in treating these open injuries, meanwhile it has the advantages of easy application, minimal additiona...

    Authors: Zi-Chen Hao, Yan Xia, De-Meng Xia, Yun-Tong Zhang and Shuo-Gui Xu
    Citation: BMC Musculoskeletal Disorders 2019 20:311
  40. Morphological variations of the EHL concern mainly the accessory tendons and the site of their insertion. The aim of our study is to present a new classification of the EHL.

    Authors: Łukasz Olewnik, Michał Podgórski, Michał Polguj, Kacper Ruzik and Mirosław Topol
    Citation: BMC Musculoskeletal Disorders 2019 20:310
  41. Distal radius fractures (DRF) are very common in elderly patients, who present at the Emergency Department. Surgical treatment with open reduction and internal fixation using volar locking plates is widely pre...

    Authors: Jonas Pedersen, Simon Oksbjerre Mortensen, Jan Duedal Rölfing and Rikke Thorninger
    Citation: BMC Musculoskeletal Disorders 2019 20:309
  42. To determine if adults with incident accelerated knee osteoarthritis (KOA) are more likely to have degenerative knee ligaments or tendons compared to individuals with typical or no KOA.

    Authors: Julie E. Davis, Matthew S. Harkey, Robert J. Ward, James W. MacKay, Bing Lu, Lori Lyn Price, Charles B. Eaton, Grace H. Lo, Mary F. Barbe, Timothy E. McAlindon and Jeffrey B. Driban
    Citation: BMC Musculoskeletal Disorders 2019 20:308
  43. Mental health has been shown to improve after total hip arthroplasty (THA). Little is known about the role of pain and function in this context. We assessed whether change in mental health was associated with ...

    Authors: Uyen-Sa D. T. Nguyen, Thomas Perneger, Patricia D. Franklin, Christophe Barea, Pierre Hoffmeyer and Anne Lübbeke
    Citation: BMC Musculoskeletal Disorders 2019 20:307
  44. The efficacy of postoperative pain management is an important factor that influences the final outcome of total knee arthroplasty (TKA). Whether liposomal bupivacaine offers better efficacy compared with tradi...

    Authors: Yuan Liu, Yi Zeng, Junfeng Zeng, Mingyang Li, Wenxing Wei and Bin Shen
    Citation: BMC Musculoskeletal Disorders 2019 20:306
  45. Transpedicular intracorporeal cement augmentation (TCA) with short segmental posterior instrumentation (SSPI), which provides an ideal immediate analgesic effect and long-term reconstructive stability, is thou...

    Authors: Hongli Deng, Yibing Li, Jinsong Zhou, Xiaodong Wang, Jinpeng Du, Wenjie Gao and Dingjun Hao
    Citation: BMC Musculoskeletal Disorders 2019 20:305
  46. Geriatric hip fracture patients are particularly susceptible to blood loss and venous thromboembolism (VTE) during hemiarthroplasty, yet relatively few studies have examined the safety and efficacy of tranexam...

    Authors: Jinwei Xie, Qinsheng Hu, Qiang Huang, Guo Chen, Zongke Zhou and Fuxing Pei
    Citation: BMC Musculoskeletal Disorders 2019 20:304
  47. Osteoarthritis (OA) leads to joint failure and total joint replacement (TJR, either hip (H) or knee (K)). Worsening of pain and joint space narrowing are believed to be surrogates for joint failure; however, w...

    Authors: Cecilie L. Bager, Morten Karsdal, Asger Bihlet, Christian Thudium, Inger Byrjalsen and Anne C. Bay-Jensen
    Citation: BMC Musculoskeletal Disorders 2019 20:303
  48. For patients with painful knee osteoarthritis, long-term symptomatic relief may improve quality of life. Cooled radiofrequency ablation (CRFA) has demonstrated significant improvements in pain, physical functi...

    Authors: Mehul Desai, Anthony Bentley, William A. Keck, Thomas Haag, Rod S. Taylor and Helen Dakin
    Citation: BMC Musculoskeletal Disorders 2019 20:302
  49. We report a case of prosthetic hip joint infection in a heart transplant recipient due to Anaerobiospirillum succiniciproducens, a genus of spiral-shaped curved anaerobic gram-negative rod which colonizes the gas...

    Authors: Gregory R. Madden, Melinda D. Poulter, Michael P. Crawford, Daniel S. Wilson and Gerald R. Donowitz
    Citation: BMC Musculoskeletal Disorders 2019 20:301
  50. Residents of rural and regional areas, compared to those in urban regions, are more likely to experience geographical difficulties in accessing healthcare, particularly specialist services. We investigated ass...

    Authors: Sharon L. Brennan-Olsen, Sara Vogrin, Stephen Graves, Kara L. Holloway-Kew, Richard S. Page, M. Amber Sajjad, Mark A. Kotowicz, Patricia M. Livingston, Mustafa Khasraw, Sharon Hakkennes, Trisha L. Dunning, Susan Brumby, Alasdair G. Sutherland, Jason Talevski, Darci Green, Thu-Lan Kelly…
    Citation: BMC Musculoskeletal Disorders 2019 20:300

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