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  1. The established treatment for bacterial arthritis of the knee joint is arthroscopic surgery with irrigation and debridement. The aim of this article is to summarize the relevant data in treating bacterial arth...

    Authors: Atesch Ateschrang, Dirk Albrecht, Steffen Schröter, Bernhard Hirt, Kuno Weise and Jürgen H Dolderer

    Citation: BMC Musculoskeletal Disorders 2011 12:180

    Content type: Technical advance

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  2. Chronic low back pain is a highly prevalent condition, which is associated with high direct and indirect costs to the society. Although this condition is highly prevalent, it is still extremely difficult to tr...

    Authors: Alessandra N Garcia, Francine LB Gondo, Renata A Costa, Fábio N Cyrillo, Tatiane M Silva, Luciola CM Costa and Leonardo OP Costa

    Citation: BMC Musculoskeletal Disorders 2011 12:179

    Content type: Study protocol

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  3. A study to evaluate the adherence to and appropriateness of anti-osteoporotic treatments in a cohort of men and women aged 50 and over participating in the ESOSVAL-R study.

    Authors: Gabriel Sanfélix-Gimeno, José Sanfélix-Genovés, Salvador Peiró, Isabel Hurtado, José Luis Trillo, Ruth Usó, Vicente Giner Ruiz, Manuel Pascual de la Torre and Inmaculada Ferreros

    Citation: BMC Musculoskeletal Disorders 2011 12:178

    Content type: Study protocol

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  4. Osteoarthritis (OA) is a prevalent chronic disease and a leading cause of disability in adults. For people with knee and hip OA, symptoms (e.g., pain and fatigue) can interfere with mobility and physical activ...

    Authors: Susan L Murphy, Angela K Lyden, Maria Clary, Michael E Geisser, Raymond L Yung, Daniel J Clauw and David A Williams

    Citation: BMC Musculoskeletal Disorders 2011 12:177

    Content type: Study protocol

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  5. Neck pain is related to impaired postural balance among patients and is highly prevalent among workers with high postural demands, for example, cleaners. We therefore hypothesised, that cleaners with neck pain...

    Authors: Marie B Jørgensen, Jørgen H Skotte, Andreas Holtermann, Gisela Sjøgaard, Nicolas C Petersen and Karen Søgaard

    Citation: BMC Musculoskeletal Disorders 2011 12:176

    Content type: Research article

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  6. Beside symptoms and clinical signs radiological findings are crucial in the diagnosis of lumbar spinal stenosis (LSS). We investigate which quantitative radiological signs are described in the literature and w...

    Authors: Johann Steurer, Simon Roner, Ralph Gnannt and Juerg Hodler

    Citation: BMC Musculoskeletal Disorders 2011 12:175

    Content type: Research article

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  7. Hypersensitivity of the central nervous system is widely present in pain patients and recognized as one of the determinants of chronic pain and disability. Electronic pressure algometry is often used to explor...

    Authors: Niklaus Egloff, Nicole Klingler, Roland von Känel, Rafael JA Cámara, Michele Curatolo, Barbara Wegmann, Elizabeth Marti and Marie-Louise Gander Ferrari

    Citation: BMC Musculoskeletal Disorders 2011 12:174

    Content type: Research article

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  8. In the light of both the importance and large numbers of case series and cohort studies (observational studies) in orthopaedic literature, it is remarkable that there is currently no validated measurement tool...

    Authors: Bart G Pijls, Olaf M Dekkers, Saskia Middeldorp, Edward R Valstar, Huub JL van der Heide, Henrica MJ Van der Linden-Van der Zwaag and Rob GHH Nelissen

    Citation: BMC Musculoskeletal Disorders 2011 12:173

    Content type: Research article

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  9. The expectations of patients for managing pain induced by exercise and mobilization (PIEM) have seldom been investigated. We identified the views of patients and care providers regarding pain management induce...

    Authors: Sophie Alami, Dominique Desjeux, Marie Martine Lefèvre-Colau, Anne Sophie Boisgard, Eric Boccard, François Rannou and Serge Poiraudeau

    Citation: BMC Musculoskeletal Disorders 2011 12:172

    Content type: Research article

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  10. There is a need for outcome measurement instruments for evaluation of disability after trauma. The Patient-Rated Wrist Evaluation (PRWE) is a self-administered region-specific outcome measuring instrument deve...

    Authors: Cecilia Mellstrand Navarro, Sari Ponzer, Hans Törnkvist, Leif Ahrengart and Gunnar Bergström

    Citation: BMC Musculoskeletal Disorders 2011 12:171

    Content type: Research article

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  11. While there is growing evidence for the efficacy of SM to treat LBP, little is known on the mechanisms and physiologic effects of these treatments. Accordingly, the purpose of this study was to determine wheth...

    Authors: Brian C Clark, David A Goss Jr, Stevan Walkowski, Richard L Hoffman, Andrew Ross and James S Thomas

    Citation: BMC Musculoskeletal Disorders 2011 12:170

    Content type: Research article

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  12. Many adults experience bothersome neck/shoulder pain. While research and treatment strategies often focus on the upper trapezius, other neck/shoulder muscles may be affected as well. The aim of the present stu...

    Authors: Lars L Andersen, Klaus Hansen, Ole S Mortensen and Mette K Zebis

    Citation: BMC Musculoskeletal Disorders 2011 12:169

    Content type: Research article

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  13. Assessment of shoulder mobility is essential for clinical follow-up of shoulder treatment. Only a few high sophisticated instruments for objective measurements of shoulder mobility are available. The interobse...

    Authors: Bilal Farouk El-Zayat, Turgay Efe, Annett Heidrich, Udo Wolf, Nina Timmesfeld, Thomas J Heyse, Stefan Lakemeier, Susanne Fuchs-Winkelmann and Markus D Schofer

    Citation: BMC Musculoskeletal Disorders 2011 12:168

    Content type: Research article

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  14. Monitoring osteoporosis therapy by measurement of bone turnover markers (BTMs) might detect non-compliance in an earlier stage of anti-osteoporosis treatment and improve persistence.

    Authors: Danielle A Eekman, Irene EM Bultink, Annemieke C Heijboer, Ben AC Dijkmans and Willem F Lems

    Citation: BMC Musculoskeletal Disorders 2011 12:167

    Content type: Research article

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  15. To determine safe surgical margins for soft tissue sarcoma, it is essential to perform a general evaluation of the extent of tumor, responses to auxiliary therapy, and other factors preoperatively using multip...

    Authors: Masahiro Yokouchi, Mikio Terahara, Satoshi Nagano, Yoshiya Arishima, Michihisa Zemmyo, Takako Yoshioka, Akihide Tanimoto and Setsuro Komiya

    Citation: BMC Musculoskeletal Disorders 2011 12:166

    Content type: Research article

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  16. Clinical analgesic trials typically report response as group mean results. However, research has shown that few patients are average and most have responses at the extremes. Moreover, group mean results do not...

    Authors: Paul M Peloso, Arnold Gammaitoni, Steven S Smugar, Hongwei Wang and Andrew R Moore

    Citation: BMC Musculoskeletal Disorders 2011 12:165

    Content type: Research article

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  17. Tenascin-C (TN-C) is an extracellular matrix glycoprotein that is involved in tissue injury and repair processes. We analyzed TN-C expression in normal and osteoarthritic (OA) human cartilage, and evaluated it...

    Authors: Lisha Patel, Weiyong Sun, Sonya S Glasson, Elisabeth A Morris, Carl R Flannery and Priya S Chockalingam

    Citation: BMC Musculoskeletal Disorders 2011 12:164

    Content type: Research article

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  18. BMP-2 is known to accelerate fracture healing and might also enhance osseointegration and implant fixation. Application of recombinant BMP-2 has a time-limited effect. Therefore, a gene transfer approach with ...

    Authors: Benjamin Faensen, Britt Wildemann, Christian Hain, Julius Höhne, Yvonne Funke, Christan Plank, Axel Stemberger and Gerhard Schmidmaier

    Citation: BMC Musculoskeletal Disorders 2011 12:163

    Content type: Research article

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  19. Increased center of pressure excursions are well documented in patients suffering from non-specific low back pain, whereby the altered postural sway includes both higher mean sway velocities and larger sway ar...

    Authors: Alexander Ruhe, René Fejer and Bruce Walker

    Citation: BMC Musculoskeletal Disorders 2011 12:162

    Content type: Research article

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  20. Despite the large volume of research dedicated to understanding chronic low back pain (CLBP), patient outcomes remain modest while healthcare costs continue to rise, creating a major public health burden. Heal...

    Authors: Andrew M Briggs, Joanne E Jordan, Peter B O'Sullivan, Rachelle Buchbinder, Angus F Burnett, Richard H Osborne and Leon M Straker

    Citation: BMC Musculoskeletal Disorders 2011 12:161

    Content type: Research article

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  21. The pathogenesis of osteonecrosis of the femoral head (ONFH) has been implicated in hypofibrinolysis and blood supply interruption. Previous studies have demonstrated that decreased fibrinolytic activity due t...

    Authors: Hye- Ok Kim, Chang- Hoon Cho, Yoon- Je Cho, Seong- Ho Cho, Kyung- Sik Yoon and Kang- Il Kim

    Citation: BMC Musculoskeletal Disorders 2011 12:160

    Content type: Research article

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  22. Authors: Wayne Hoskins, Henry Pollard, Chris Daff, Andrew Odell, Peter Garbutt, Andrew McHardy, Kate Hardy and George Dragasevic

    Citation: BMC Musculoskeletal Disorders 2011 12:159

    Content type: Retraction Note

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    The original article was published in BMC Musculoskeletal Disorders 2010 11:241

  23. Citation: BMC Musculoskeletal Disorders 2011 12:158

    Content type: Retraction Note

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    The original article was published in BMC Musculoskeletal Disorders 2009 10:38

  24. Musculoskeletal diseases are becoming increasingly important due to population aging. However, studies on the economic burden of musculoskeletal disease in Korea are scarce. Therefore, we conducted a populatio...

    Authors: In-Hwan Oh, Seok-Jun Yoon, Hye-Young Seo, Eun-Jung Kim and Young Ae Kim

    Citation: BMC Musculoskeletal Disorders 2011 12:157

    Content type: Research article

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  25. There is limited evidence for the clinical and cost effectiveness of occupational therapy (OT) approaches in the management of hand osteoarthritis (OA). Joint protection and hand exercises have been proposed b...

    Authors: Krysia S Dziedzic, Susan Hill, Elaine Nicholls, Alison Hammond, Helen Myers, Tracy Whitehurst, Jo Bailey, Charlotte Clements, David GT Whitehurst, Sue Jowett, June Handy, Rhian W Hughes, Elaine Thomas and Elaine M Hay

    Citation: BMC Musculoskeletal Disorders 2011 12:156

    Content type: Study protocol

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  26. Even though technological progress has provided us with more and more sophisticated equipment for making goniometric measurements, the most commonly used clinical tools are still the universal goniometer and, ...

    Authors: Pablo Herrero, Patricia Carrera, Elena García, Eva M Gómez-Trullén and Bárbara Oliván-Blázquez

    Citation: BMC Musculoskeletal Disorders 2011 12:155

    Content type: Research article

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  27. Subacromial disorders are considered to be one of the most common pathologies affecting the shoulder. Optimal therapy for shoulder pain (SP) in primary care is yet unknown, since clinical history and physical ...

    Authors: Ramon PG Ottenheijm, Manuela A Joore, Geert HIM Walenkamp, René E Weijers, Bjorn Winkens, Jochen WL Cals, Rob A de Bie and Geert-Jan Dinant

    Citation: BMC Musculoskeletal Disorders 2011 12:154

    Content type: Study protocol

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  28. Canakinumab is a fully human anti-interleukin IL-1beta monoclonal antibody, being investigated for the treatment of rheumatoid arthritis (RA). This multicenter, phase II, randomized, double-blind, placebo-cont...

    Authors: Rieke Alten, Juan Gomez-Reino, Patrick Durez, Andre Beaulieu, Anthony Sebba, Gerhard Krammer, Ralph Preiss, Udayasankar Arulmani, Albert Widmer, Xavier Gitton and Herbert Kellner

    Citation: BMC Musculoskeletal Disorders 2011 12:153

    Content type: Research article

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  29. Brief intervention programs are clinically beneficial, and cost efficient treatments for low back pain, when offered at 8-12 weeks, compared with treatment as usual. However, about 30% of the patients do not r...

    Authors: Silje E Reme, Torill H Tveito, Trudie Chalder, Tormod Bjørkkjær, Aage Indahl, Jens I Brox, Egil Fors, Eli M Hagen and Hege R Eriksen

    Citation: BMC Musculoskeletal Disorders 2011 12:152

    Content type: Study protocol

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  30. Posttraumatic osteoarthritis can develop after an intra-articular extremity fracture, leading to pain and loss of function. According to international guidelines, anatomical reduction and fixation are the basi...

    Authors: M Suzan H Beerekamp, Dirk Th Ubbink, Mario Maas, Jan SK Luitse, Peter Kloen, Taco JM Blokhuis, Michiel JM Segers, Meir Marmor, Niels WL Schep, Marcel GW Dijkgraaf and J Carel Goslings

    Citation: BMC Musculoskeletal Disorders 2011 12:151

    Content type: Study protocol

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  31. Regulation of cell death and cell division are key processes during chondrogenesis and in cartilage homeostasis and pathology. The oncogene survivin is considered to be critical for the coordination of mitosis...

    Authors: Philipp Lechler, Sanjeevi Balakrishnan, Jens Schaumburger, Susanne Grässel, Clemens Baier, Joachim Grifka, Rainer H Straub and Tobias Renkawitz

    Citation: BMC Musculoskeletal Disorders 2011 12:150

    Content type: Research article

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  32. A high quality decision requires that patients who meet clinical criteria for surgery are informed about the options (including non-surgical alternatives) and receive treatments that match their goals. The aim...

    Authors: Karen R Sepucha, Dawn Stacey, Catharine F Clay, Yuchiao Chang, Carol Cosenza, Geoffrey Dervin, Janet Dorrwachter, Sandra Feibelmann, Jeffrey N Katz, Stephen A Kearing, Henrik Malchau, Monica Taljaard, Ivan Tomek, Peter Tugwell and Carrie A Levin

    Citation: BMC Musculoskeletal Disorders 2011 12:149

    Content type: Research article

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  33. Ankle fractures are common. Management of ankle fractures generally involves a period of immobilisation followed by rehabilitation to reduce pain, stiffness, weakness and swelling. The effects of a rehabilitat...

    Authors: Paula R Beckenkamp, C Christine Lin, Robert D Herbert, Marion Haas, Kriti Khera and Anne M Moseley

    Citation: BMC Musculoskeletal Disorders 2011 12:148

    Content type: Study protocol

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  34. The present study was conducted to address whether the intervertebral disc of rabbit could be considered (i) as a valuable model to provide new insights into the tissue and cellular changes of Nucleus pulposus...

    Authors: Johann Clouet, Marianne Pot-Vaucel, Gaël Grimandi, Martial Masson, Julie Lesoeur, Borhane H Fellah, Olivier Gauthier, Marion Fusellier, Yan Cherel, Yves Maugars, Jérôme Guicheux and Claire Vinatier

    Citation: BMC Musculoskeletal Disorders 2011 12:147

    Content type: Research article

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  35. Patients with non-specific back pain are not a homogeneous group but heterogeneous with regard to their bio-psycho-social impairments. This study examined a sample of 173 highly disabled patients with chronic ...

    Authors: Martin L Verra, Felix Angst, J Bart Staal, Roberto Brioschi, Susanne Lehmann, André Aeschlimann and Rob A de Bie

    Citation: BMC Musculoskeletal Disorders 2011 12:145

    Content type: Research article

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  36. One of the sources of knee pain in osteoarthritis (OA) is believed to be related to local chronic inflammation of the knee joints, which involves the production of inflammatory cytokines such as tumor necrosis...

    Authors: Sumihisa Orita, Takana Koshi, Takeshi Mitsuka, Masayuki Miyagi, Gen Inoue, Gen Arai, Tetsuhiro Ishikawa, Eiji Hanaoka, Keishi Yamashita, Masaomi Yamashita, Yawara Eguchi, Tomoaki Toyone, Kazuhisa Takahashi and Seiji Ohtori

    Citation: BMC Musculoskeletal Disorders 2011 12:144

    Content type: Research article

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  37. Previous research has found that acceptance of pain is more successful than cognitive coping variables for predicting adjustment to pain. This research has a limitation because measures of cognitive coping rel...

    Authors: Baltasar Rodero, Benigno Casanueva, Juan V Luciano, Margalida Gili, Antoni Serrano-Blanco and Javier García-Campayo

    Citation: BMC Musculoskeletal Disorders 2011 12:143

    Content type: Research article

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  38. Low-contact-stress (LCS) mobile-bearing total knee arthroplasty (TKA) (Johnson & Johnson, New Brunswick, NJ; previously: DePuy, Warsawa, USA) provides excellent functional results and wear rates in long-term f...

    Authors: Patrick Sadoghi, Andreas Leithner, Patrick Weber, Jörg Friesenbichler, Gerald Gruber, Norbert Kastner, Katrin Pohlmann, Volkmar Jansson and Bernd Wegener

    Citation: BMC Musculoskeletal Disorders 2011 12:142

    Content type: Research article

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  39. Patients with osteoarthritis of the knee may change their gait in an attempt to reduce loading of the affected knee, thereby reducing pain. Especially changes in lateral trunk motion may be potentially effecti...

    Authors: Martin van der Esch, Martijn PM Steultjens, Jaap Harlaar, Josien C van den Noort, Dirk L Knol and Joost Dekker

    Citation: BMC Musculoskeletal Disorders 2011 12:141

    Content type: Research article

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  40. Polymethylmethacrylate (PMMA) assisted ventral discectomy has been criticized for high rates of graft migration and pseudarthrosis when compared with various other fusion procedures for the treatment of cervic...

    Authors: Mario Cabraja, Daniel Koeppen, Wolfgang R Lanksch, Klaus Maier-Hauff and Stefan Kroppenstedt

    Citation: BMC Musculoskeletal Disorders 2011 12:140

    Content type: Research article

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  41. Shoulder pain is reported to be highly prevalent and tends to be recurrent or persistent despite medical treatment. The pathophysiological mechanisms of shoulder pain are poorly understood. Furthermore, there ...

    Authors: Carel Bron, Jan Dommerholt, Boudewijn Stegenga, Michel Wensing and Rob AB Oostendorp

    Citation: BMC Musculoskeletal Disorders 2011 12:139

    Content type: Research article

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  42. Although no prospective studies have compared functional results of trochanteric osteotomy and a non-trochanteric approach, most surgeons feel that trochanteric osteotomy is outdated in simple hip arthroplasty...

    Authors: Margot van der Grinten, Max Reijman, Frans C van Biezen and Jan AN Verhaar

    Citation: BMC Musculoskeletal Disorders 2011 12:138

    Content type: Research article

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  43. Corticosteroid injections can be performed blind (landmark-guided) or with image guidance, and this may account for variable clinical outcomes. The objective of this study was to assess the effectiveness and s...

    Authors: Edmund Soh, Wenyun Li, Keh Oon Ong, Wen Chen and Dianne Bautista

    Citation: BMC Musculoskeletal Disorders 2011 12:137

    Content type: Research article

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  44. Dupuytren's disease is a progressive fibroproliferative disorder which can result in fixed flexion contractures of digits and impaired hand function. Standard treatment involves surgical release or excision fo...

    Authors: Christina Jerosch-Herold, Lee Shepstone, Adrian J Chojnowski, Debbie Larson, Elisabeth Barrett and Susan P Vaughan

    Citation: BMC Musculoskeletal Disorders 2011 12:136

    Content type: Research article

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  45. There remains uncertainty regarding the appropriate therapeutic management of hip fracture patients. The primary aim of our study was to examine whether large loading doses in addition to daily vitamin D offer...

    Authors: Alexandra Papaioannou, Courtney C Kennedy, Lora Giangregorio, George Ioannidis, Janet Pritchard, David A Hanley, Leonardo Farrauto, Justin DeBeer and Jonathan D Adachi

    Citation: BMC Musculoskeletal Disorders 2011 12:135

    Content type: Research article

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  46. The exact mechanism of knee osteoarthritis (OA)-associated pain is unclear, whereas mixed evidence of inflammatory pain and neuropathic pain has been noted. We aimed to investigate pain-related sensory innerva...

    Authors: Sumihisa Orita, Tetsuhiro Ishikawa, Masayuki Miyagi, Nobuyasu Ochiai, Gen Inoue, Yawara Eguchi, Hiroto Kamoda, Gen Arai, Tomoaki Toyone, Yasuchika Aoki, Takekazu Kubo, Kazuhisa Takahashi and Seiji Ohtori

    Citation: BMC Musculoskeletal Disorders 2011 12:134

    Content type: Research article

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  47. Recent systematic reviews on psychological therapies of fibromyalgia syndrome (FMS) did not consider hypnosis/guided imagery (H/GI). Therefore we performed a systematic review with meta-analysis of the efficac...

    Authors: Kathrin Bernardy, Nicole Füber, Petra Klose and Winfried Häuser

    Citation: BMC Musculoskeletal Disorders 2011 12:133

    Content type: Research article

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  48. Achieving adequate follow-up in clinical trials is essential to establish the validity of the findings. Achieving adequate response rates reduces bias and increases probability that the findings can be general...

    Authors: John D Childs, Deydre S Teyhen, Joshua J Van Wyngaarden, Brett F Dougherty, Bryan J Ladislas, Gary L Helton, Michael E Robinson, Samuel S Wu and Steven Z George

    Citation: BMC Musculoskeletal Disorders 2011 12:132

    Content type: Research article

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  49. Many studies have identified smoking as a risk factor for osteoporosis, but it is unclear whether passive smoking has an effect on bone mineral density and bone turnover and if such an effect could cause osteo...

    Authors: Shu-guang Gao, Kang-hua Li, Mai Xu, Wei Jiang, Hong Shen, Wei Luo, Wen-shuo Xu, Jian Tian and Guang-hua Lei

    Citation: BMC Musculoskeletal Disorders 2011 12:131

    Content type: Research article

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