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  1. Though sera are essential for Mesenchymal stem cells (MSCs), the effect of heat-inactivation remains unknown. Autologous human serum is recommended for clinical use; however, it is unclear whether differentiat...

    Authors: Akimoto Nimura, Takeshi Muneta, Koji Otabe, Hideyuki Koga, Young-Jin Ju, Tomoyuki Mochizuki, Koji Suzuki and Ichiro Sekiya

    Citation: BMC Musculoskeletal Disorders 2010 11:208

    Content type: Research article

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  2. High tibial osteotomy (HTO) is a well established technique for the treatment of medial osteoarthritis of the knee with varus malalignment. Results of total knee arthroplasty (TKA) after previous HTO are still...

    Authors: Turgay Efe, Thomas J Heyse, Christoph Boese, Nina Timmesfeld, Susanne Fuchs-Winkelmann, Jan Schmitt, Christina Theisen and Markus D Schofer

    Citation: BMC Musculoskeletal Disorders 2010 11:207

    Content type: Research article

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  3. Chronic back pain is a significant problem worldwide and may be especially prevalent among patients receiving care in the U.S. Department of Veterans Affairs healthcare system. Back pain affects adults at all ...

    Authors: Sarah L Krein, Tabitha Metreger, Reema Kadri, Maria Hughes, Eve A Kerr, John D Piette, Hyungjin Myra Kim and Caroline R Richardson

    Citation: BMC Musculoskeletal Disorders 2010 11:205

    Content type: Study protocol

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  4. Despite its frequent use as a hypnotic, trazodone has not been systematically assessed in fibromyalgia patients. In the present study have we evaluated the potential effectiveness and tolerability of trazodone...

    Authors: Piedad Morillas-Arques, Carmen Ma Rodriguez-Lopez, Rocio Molina-Barea, Fernando Rico-Villademoros and Elena P Calandre

    Citation: BMC Musculoskeletal Disorders 2010 11:204

    Content type: Research article

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  5. This is the first longitudinal study with a 22-year follow-up, based on a national and complete sample, to determine whether the prevalence of hip fracture and the age when it occurs are influenced by migratio...

    Authors: Björn Albin, Katarina Hjelm and Sölve Elmståhl

    Citation: BMC Musculoskeletal Disorders 2010 11:203

    Content type: Research article

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  6. Detection of nerve involvement originating in the spine is a primary concern in the assessment of spine symptoms. Magnetic resonance imaging (MRI) has become the diagnostic method of choice for this detection....

    Authors: Bo C Bertilson, Eva Brosjö, Hans Billing and Lars-Erik Strender

    Citation: BMC Musculoskeletal Disorders 2010 11:202

    Content type: Research article

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  7. Patellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle and older age, but its relation to PF disorders and symptoms earlier in life is unclear. Our aim was to conduct a systematic review to...

    Authors: Martin J Thomas, Laurence Wood, James Selfe and George Peat

    Citation: BMC Musculoskeletal Disorders 2010 11:201

    Content type: Research article

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  8. Shoulder complaints are common in primary care and have unfavourable long term prognosis. Our objective was to evaluate the clinical effectiveness of manipulative therapy of the cervicothoracic spine and the a...

    Authors: Gert JD Bergman, Jan C Winter, Maurits W van Tulder, Betty Meyboom-de Jong, Klaas Postema and Geert JMG van der Heijden

    Citation: BMC Musculoskeletal Disorders 2010 11:200

    Content type: Research article

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  9. Because of the implant-related problems with pedicle screw-based spinal instrumentations, other types of fixation have been tried in spinal arthrodesis. One such technique is the direct trans-pedicular, trans-...

    Authors: Christof Birkenmaier, Olaf Suess, Michael Pfeiffer, Ralf Burger, Kirsten Schmieder and Bernd Wegener

    Citation: BMC Musculoskeletal Disorders 2010 11:199

    Content type: Study protocol

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  10. Submaximal exercise is used in the management of muscular dystrophy. The effects of mechanical stimulation on skeletal development are well understood, although its effects on cartilage growth have yet to be i...

    Authors: David J Nye, Jeffrey M Costas, Jessica B Henley, Jin-Kwang Kim and Jeffrey H Plochocki

    Citation: BMC Musculoskeletal Disorders 2010 11:198

    Content type: Research article

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  11. To develop a population-based cohort of people with ankylosing spondylitis (AS) in Wales using (1) secondary care clinical datasets, (2) patient-derived questionnaire data and (3) routinely-collected informati...

    Authors: Mark D Atkinson, Sinead Brophy, Stefan Siebert, Mike B Gravenor, Ceri Phillips, David V Ford, Kerina H Jones and Ronan A Lyons

    Citation: BMC Musculoskeletal Disorders 2010 11:197

    Content type: Study protocol

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  12. Distance running is a popular recreational exercise. It is a beneficial activity for health and well being. However, running may also cause injuries, especially of the lower extremities. In literature there is...

    Authors: Steef W Bredeweg, Sjouke Zijlstra and Ida Buist

    Citation: BMC Musculoskeletal Disorders 2010 11:196

    Content type: Study protocol

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  13. Weight-bearing and high intensity physical activities are particularly beneficial for stimulating bone growth in children given that bone responds favorably to mechanical load. While it is important to assess ...

    Authors: Christina D Economos, Erin Hennessy, Jennifer M Sacheck, M Kyla Shea and Elena N Naumova

    Citation: BMC Musculoskeletal Disorders 2010 11:195

    Content type: Research article

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  14. The aims of this study were to evaluate the construct validity (known group), concurrent validity (criterion based) and test-retest (intra-rater) reliability of manual goniometers to measure passive hip range ...

    Authors: Silvio Nussbaumer, Michael Leunig, Julia F Glatthorn, Simone Stauffacher, Hans Gerber and Nicola A Maffiuletti

    Citation: BMC Musculoskeletal Disorders 2010 11:194

    Content type: Research article

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  15. Many authors have reported about the high prevalence rates of self-reported back pain in children. Nevertheless, little is known about the diagnosis of back disorders - regardless of whether the diagnosis is a...

    Authors: Elke B Ochsmann, Carlos L Escobar Pinzón, Stephan Letzel, Thomas Kraus, Martina Michaelis and Eva Muenster

    Citation: BMC Musculoskeletal Disorders 2010 11:193

    Content type: Research article

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  16. Rheumatoid Arthritis (RA) is a chronic autoimmune inflammatory disorder. Although the pathogenesis of disease is unclear, it is well known that T cells play a major role in both development and perpetuation of...

    Authors: Atil Bisgin, Ender Terzioglu, Cigdem Aydin, Burcak Yoldas, Veli Yazisiz, Nilufer Balci, Huseyin Bagci, Reginald M Gorczynski, Cezmi A Akdis and Salih Sanlioglu

    Citation: BMC Musculoskeletal Disorders 2010 11:192

    Content type: Research article

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  17. Long head biceps (LHB) degeneration in combination with rotator cuff tears can be a source of chronic shoulder pain. LHB tenotomy is an approved surgical procedure for pain reduction and improvement of joint f...

    Authors: Stefan Lakemeier, Johannes JA Reichelt, Nina Timmesfeld, Susanne Fuchs-Winkelmann, Juergen RJ Paletta and Markus D Schofer

    Citation: BMC Musculoskeletal Disorders 2010 11:191

    Content type: Research article

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  18. Low back pain commonly affects work ability, but little is known about the work-related help and advice that patients receive from GPs and other clinicians. The purpose of this study was to explore the experie...

    Authors: Carol Coole, Paul J Watson and Avril Drummond

    Citation: BMC Musculoskeletal Disorders 2010 11:190

    Content type: Research article

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  19. Disc degeneration is characterized by a loss of cellularity, degradation of the extracellular matrix, and, as a result, morphological changes and biomechanical alterations. We hypothesized that the distributio...

    Authors: Delphine Périé and Daniel Curnier

    Citation: BMC Musculoskeletal Disorders 2010 11:189

    Content type: Research article

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  20. Although pulsed electromagnetic field (PEMF) stimulation may be clinically beneficial during fracture healing and for a wide range of bone disorders, there is still debate on its working mechanism. Mesenchymal...

    Authors: Justus HW Jansen, Olav P van der Jagt, Bas J Punt, Jan AN Verhaar, Johannes PTM van Leeuwen, Harrie Weinans and Holger Jahr

    Citation: BMC Musculoskeletal Disorders 2010 11:188

    Content type: Research article

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  21. Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific for RA, but are not detectable in all RA patients. The aim of this study was to establish whether the clinical phenotypes of anti-CCP...

    Authors: Mohammed Z Cader, Andrew D Filer, Christopher D Buckley and Karim Raza

    Citation: BMC Musculoskeletal Disorders 2010 11:187

    Content type: Research article

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  22. Prognostic assessment tools to identify subgroups of patients at risk of persistent low back pain who may benefit from targeted treatments have been developed and validated in primary care. The IMPaCT Back stu...

    Authors: Nadine E Foster, Ricky Mullis, Julie Young, Carol Doyle, Martyn Lewis, David Whitehurst and Elaine M Hay

    Citation: BMC Musculoskeletal Disorders 2010 11:186

    Content type: Study protocol

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  23. Loss of bone quality and deterioration of articular cartilage are commonly seen after menopause. While exercise may protect against tissue degeneration, a clear link has yet to be established. The aim of the p...

    Authors: Ting-Kuo Chang, Chang-Hung Huang, Chun-Hsiung Huang, Hsuan-Chiang Chen and Cheng-Kung Cheng

    Citation: BMC Musculoskeletal Disorders 2010 11:185

    Content type: Research article

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  24. Controversy exists regarding the optimal treatment for patients with displaced intracapsular fractures of the proximal femur. The recognised treatment alternatives are arthroplasty and internal fixation. The p...

    Authors: Xavier Luke Griffin, Nick Parsons, Juul Achten and Matthew L Costa

    Citation: BMC Musculoskeletal Disorders 2010 11:184

    Content type: Study protocol

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  25. By analyzing the clinical features and risk factors in female patients with musculoskeletal symptoms of Southwest China, this report presents the initial analysis of characteristics in this region and compared...

    Authors: Shasha Li, Hongchen He, Mingfu Ding and Chengqi He

    Citation: BMC Musculoskeletal Disorders 2010 11:183

    Content type: Research article

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  26. The purpose of the study was to evaluate the validity of the self-administered Aberdeen Measures of Impairment, Activity Limitation and Participation Restriction (Ab-IAP): by investigating how participants int...

    Authors: Jeremy Horwood, Beth Pollard, Salma Ayis, Teresa McIlvenna and Marie Johnston

    Citation: BMC Musculoskeletal Disorders 2010 11:182

    Content type: Research article

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  27. To compare the microRNA (miRNA) expression profiles in neurons and innervated muscles after sciatic nerve entrapment using a non-constrictive silastic tube, subsequent surgical decompression, and denervation i...

    Authors: Cheng-Shyuan Rau, Jonathan Chris Jeng, Seng-Feng Jeng, Tsu-Hsiang Lu, Yi-Chun Chen, Po-Chou Liliang, Chia-Jung Wu, Chia-Jung Lin and Ching-Hua Hsieh

    Citation: BMC Musculoskeletal Disorders 2010 11:181

    Content type: Research article

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  28. This study examined the effect of treatment with a novel biomechanical device on the level of pain and function in patients with knee OA.

    Authors: Yaron Bar-Ziv, Yiftah Beer, Yuval Ran, Shaike Benedict and Nahum Halperin

    Citation: BMC Musculoskeletal Disorders 2010 11:179

    Content type: Research article

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  29. To identify clinical questions and assessments regarded by health care practitioners as important when assessing undifferentiated hand pain or problems in adults aged 50 years and over presenting to primary care.

    Authors: Helen Myers, Elaine Thomas and Krysia Dziedzic

    Citation: BMC Musculoskeletal Disorders 2010 11:178

    Content type: Research article

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  30. Literature abounds on the prevalent nature of Self Reported Musculoskeletal Symptoms (SRMS) among computer users, but studies that actually compared this with non computer users are meagre thereby reducing the...

    Authors: O Ayanniyi, BOO Ukpai and AF Adeniyi

    Citation: BMC Musculoskeletal Disorders 2010 11:177

    Content type: Research article

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  31. Psoas abscess is a rare condition consisting of pyomyositis of the psoas. The worldwide incidence was 12 cases per 100,000 per year in 1992, but the current incidence is unknown. Psoas abscess can descend alon...

    Authors: Zhongjie Zhou, Yueming Song, Qianyun Cai and Jiancheng Zeng

    Citation: BMC Musculoskeletal Disorders 2010 11:176

    Content type: Case report

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  32. Hip dislocation after arthroplasty for femoral neck fractures remains a serious complication. The aim of our study was to investigate the dislocation rate in acute femoral neck fracture patients operated with ...

    Authors: Sarunas Tarasevicius, Mantas Busevicius, Otto Robertsson and Hans Wingstrand

    Citation: BMC Musculoskeletal Disorders 2010 11:175

    Content type: Research article

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  33. "Arthritis" is a common musculoskeletal condition but the knowledge of what type of arthritis people have, may be limited but may have changed over time in response to campaigns, increased awareness and improv...

    Authors: Tiffany K Gill, Catherine L Hill, Robert J Adams, Danny Broderick, Julie Black and Anne W Taylor

    Citation: BMC Musculoskeletal Disorders 2010 11:174

    Content type: Research article

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  34. Neck and shoulder complaints are common among employees in sedentary occupations characterized by intensive computer use. Specific strength training is a promising type of physical exercise for relieving neck ...

    Authors: Lars L Andersen, Mette K Zebis, Mogens T Pedersen, Kirsten K Roessler, Christoffer H Andersen, Mette M Pedersen, Helene Feveile, Ole S Mortensen and Gisela Sjøgaard

    Citation: BMC Musculoskeletal Disorders 2010 11:173

    Content type: Study protocol

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  35. In the face of costly fixation hardware with varying performance for treatment of distal humeral fractures, a novel technique (U-Frame) is proposed using conventional implants in a 180° plate arrangement. In t...

    Authors: Markus Windolf, Edgardo Ramos Maza, Boyko Gueorguiev, Volker Braunstein and Karsten Schwieger

    Citation: BMC Musculoskeletal Disorders 2010 11:172

    Content type: Research article

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  36. Metabolic syndrome (MetS) is increasingly common. Obesity has been suggested to associate with neck pain but prevalence of neck pain in subjects with MetS has not been studied. Aim of this study was to analyse...

    Authors: Pekka Mäntyselkä, Hannu Kautiainen and Mauno Vanhala

    Citation: BMC Musculoskeletal Disorders 2010 11:171

    Content type: Research article

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  37. Although there is much known about the role of BMPs in cartilage metabolism reliable data about the in vivo regulation in natural and surgically induced cartilage repair are still missing.

    Authors: Hagen Schmal, Philipp Niemeyer, Jörn Zwingmann, Fabian Stoffel, Norbert P Südkamp and Alexander T Mehlhorn

    Citation: BMC Musculoskeletal Disorders 2010 11:170

    Content type: Research article

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  38. Clinical practice guidelines recommend that the initial treatment of acute low back pain (LBP) should consist of advice to stay active and regular simple analgesics such as paracetamol 4 g daily. Despite this ...

    Authors: Christopher M Williams, Jane Latimer, Christopher G Maher, Andrew J McLachlan, Chris W Cooper, Mark J Hancock, Richard O Day, James H McAuley and Chung-Wei Christine Lin

    Citation: BMC Musculoskeletal Disorders 2010 11:169

    Content type: Study protocol

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  39. In both clinical and occupational settings, ambulatory sensors are becoming common for assessing all day measurements of arm motion. In order for the motion of a healthy, contralateral side to be used as a con...

    Authors: Miguel Acuna, Tal Amasay and Andrew R Karduna

    Citation: BMC Musculoskeletal Disorders 2010 11:168

    Content type: Research article

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  40. The purpose of this prospective consecutive multicenter study was to investigate whether the type of surgical approach (medial parapatellar (MPA) or lateral parapatellar with tibial tubercle osteotomy (TubOT))...

    Authors: Michael T Hirschmann, Mathias Hoffmann, Robert Krause, Reza-Amir Jenabzadeh, Markus P Arnold and Niklaus F Friederich

    Citation: BMC Musculoskeletal Disorders 2010 11:167

    Content type: Research article

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  41. Shoulder pain is a common health problem. The purpose of this study was to assess the associations of lifestyle factors, metabolic factors and carotid intima-media thickness with shoulder pain and chronic (> 3...

    Authors: Martti Rechardt, Rahman Shiri, Jaro Karppinen, Antti Jula, Markku Heliövaara and Eira Viikari-Juntura

    Citation: BMC Musculoskeletal Disorders 2010 11:165

    Content type: Research article

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  42. Severely collapsed vertebral compression fracture (VCF) is usually considered as a contraindication for vertebroplasty because of critically decreased vertebral height (less than one-third the original height)...

    Authors: Meng-Huang Wu, Tsung-Jen Huang, Chin-Chang Cheng, Yen-Yao Li and Robert Wen-Wei Hsu

    Citation: BMC Musculoskeletal Disorders 2010 11:164

    Content type: Research article

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  43. Current evidence supports the use of exercise-based treatment for chronic low back pain that encourages the patient to assume an active role in their recovery. Walking has been shown it to be an acceptable typ...

    Authors: Suzanne M McDonough, Mark A Tully, Seán R O'Connor, Adele Boyd, Daniel P Kerr, Siobhán M O'Neill, Antony Delitto, Ian Bradbury, Catrine Tudor-Locke, David G Baxter and Deirdre A Hurley

    Citation: BMC Musculoskeletal Disorders 2010 11:163

    Content type: Study protocol

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  44. Glucosamine (GlcN) is a well-recognized candidate for treatment of osteoarthritis. However, it is currently used in derivative forms, such as glucosamine-hydrochloride (GlcN-HCl) or glucosamine sulfate (GlcN-S...

    Authors: Thanyaluck Phitak, Peraphan Pothacharoen and Prachya Kongtawelert

    Citation: BMC Musculoskeletal Disorders 2010 11:162

    Content type: Research article

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  45. Hip surface replacement arthroplasty (SRA) can be an alternative for total hip arthroplasty. The short and long-term outcome of hip surface replacement arthroplasty mainly relies on the optimal size and positi...

    Authors: Martijn Raaijmaakers, Frederik Gelaude, Karla De Smedt, Tim Clijmans, Jeroen Dille and Michiel Mulier

    Citation: BMC Musculoskeletal Disorders 2010 11:161

    Content type: Technical advance

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  46. Studies on critical pathway use have demonstrated decreased length of stay and cost without compromise in quality of care. However, pathway effectiveness is difficult to determine given methodological flaws, s...

    Authors: Ms Elaine Husni, Elena Losina, Anne H Fossel, Daniel H Solomon, Nizar N Mahomed and Jeffrey N Katz

    Citation: BMC Musculoskeletal Disorders 2010 11:160

    Content type: Research article

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  47. High morbidity has been reported with iliac crest bone graft harvesting; however, donor bone is typically necessary for posterior spinal fusion. Autograft bone combined with allograft may reduce the morbidity ...

    Authors: Xiaoming Yang, Hongguang Xu, Ming Li, Suxi Gu, Xiutong Fang, Jingjie Wang, Jianqiang Ni and Dajiang Wu

    Citation: BMC Musculoskeletal Disorders 2010 11:159

    Content type: Research article

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