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  1. Osteoarthritis (OA) is a major health problem in the increasingly elderly population. Therefore, it is crucial to prevent and treat OA at an early stage. The present study investigated whether pamidronate diso...

    Authors: You Lv, Jie-yun Xia, Jing-yang Chen, Hui Zhao, Hai-cui Yan, Han-shi Yang, Qiang Li, Yu-xin Fan, Kai-jin Guo and Xiang-yang Chen

    Citation: BMC Musculoskeletal Disorders 2014 15:370

    Content type: Research article

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  2. The aim of this cadaveric study was to compare a polyaxial (NCB®, Zimmer) to a fixed-angle monoaxial locking plate (PERILOC®, Smith & Nephew) in comminuted fractures of the distal femur regarding stability of ...

    Authors: Bilal Farouk El-Zayat, Turgay Efe, Steffen Ruchholtz, Salim Khatib, Nina Timmesfeld, Antonio Krüger and Ralph Zettl

    Citation: BMC Musculoskeletal Disorders 2014 15:369

    Content type: Research article

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  3. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are two commonly used measures of inflammation in rheumatoid arthritis (RA). As current RA treatment guidelines strongly emphasize early an...

    Authors: Liseth Siemons, Peter M ten Klooster, Harald E Vonkeman, Piet LCM van Riel, Cees AW Glas and Mart AFJ van de Laar

    Citation: BMC Musculoskeletal Disorders 2014 15:368

    Content type: Research article

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  4. The purpose of this study was to investigate the occurrence and factors associated with postoperative shoulder imbalance (PSI) in Lenke type 1A curve.

    Authors: Morio Matsumoto, Kota Watanabe, Noriaki Kawakami, Taichi Tsuji, Koki Uno, Teppei Suzuki, Manabu Ito, Haruhisa Yanagida, Shohei Minami and Tsutomu Akazawa

    Citation: BMC Musculoskeletal Disorders 2014 15:366

    Content type: Research article

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  5. A Moroccan model for the FRAX tool to determine the absolute risk of osteoporotic fracture at 10 years has been established recently. The study aimed to assess the discriminative capacity of FRAX in identifyin...

    Authors: Abdellah El Maghraoui, Siham Sadni, Nabil Jbili, Asmaa Rezqi, Aziza Mounach and Imad Ghozlani

    Citation: BMC Musculoskeletal Disorders 2014 15:365

    Content type: Research article

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  6. Previous studies have not addressed rheumatoid arthritis (RA) patients’ help-seeking behaviours for RA flares, and only one small qualitative study has addressed how patients experience daily life on current t...

    Authors: Caroline A Flurey, Marianne Morris, Jon Pollock, Pamela Richards, Rodney Hughes and Sarah Hewlett

    Citation: BMC Musculoskeletal Disorders 2014 15:364

    Content type: Research article

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  7. This study assessed the mortality and complications of hip fractures using in-patients aged 20–40 years from a nationwide population database in Taiwan.

    Authors: Jeff Chien-Fu Lin, Cheng-Chun Wu, Chi Lo, Wen-Miin Liang, Chi-Fung Cheng, Chang-Bi Wang, Yu-Jun Chang, Hsi-Chin Wu and Tsai-Hsueh Leu

    Citation: BMC Musculoskeletal Disorders 2014 15:362

    Content type: Research article

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  8. Dupuytren’s contracture is a progressive, fibroproliferative disorder that causes fixed finger contractures and can lead to disability. With the advances of new therapeutic interventions, the necessity to asse...

    Authors: Nancy J Forget, Christina Jerosch-Herold, Lee Shepstone and Johanne Higgins

    Citation: BMC Musculoskeletal Disorders 2014 15:361

    Content type: Research article

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  9. This study was to compare clinical and radiographic outcomes with three different implants and evaluate the effectiveness of minimally invasive plate osteosynthesis (MIPO) technique for the distal fibular frac...

    Authors: ZeYu Huang, Lei Liu, ChongQi Tu, Hui Zhang, Yue Fang, TianFu Yang and FuXing Pei

    Citation: BMC Musculoskeletal Disorders 2014 15:360

    Content type: Research article

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  10. Anterior knee pain may occur after total knee arthroplasty (TKA). Patellar resurfacing, which is considered to lower the incidence of anterior knee pain after TKA, remains controversial. In the present study c...

    Authors: Maria JFJ Bischoff, Tom M van Raaij, Inge HF Reininga and Jos JAM van Raay

    Citation: BMC Musculoskeletal Disorders 2014 15:358

    Content type: Study protocol

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  11. This study compares the levels of algesic substances between subjects with trapezius myalgia (TM) and healthy controls (CON) and explores the multivariate correlation pattern between these substances, pain, an...

    Authors: Björn Gerdle, Jesper Kristiansen, Britt Larsson, Bengt Saltin, Karen Søgaard and Gisela Sjøgaard

    Citation: BMC Musculoskeletal Disorders 2014 15:357

    Content type: Research article

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  12. Relatively little is known about the social distribution of total knee joint replacement (TKR) uptake in Australia. We examine associations between socioeconomic status (SES) and TKR performed for diagnosed os...

    Authors: Sharon L Brennan, Stephen E Lane, Michelle Lorimer, Rachelle Buchbinder, Anita E Wluka, Richard S Page, Richard H Osborne, Julie A Pasco, Kerrie M Sanders, Kara Cashman, Peter R Ebeling and Stephen E Graves

    Citation: BMC Musculoskeletal Disorders 2014 15:356

    Content type: Research article

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  13. The natural history of hip instability (without subluxation or dislocation) and treatment in infants remain controversial. We performed a retrospective cohort case-only study with blinded, prospectively collec...

    Authors: Blazej Pruszczynski, H Theodore Harcke, Laurens Holmes Jr and J Richard Bowen

    Citation: BMC Musculoskeletal Disorders 2014 15:355

    Content type: Research article

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  14. Total hip replacement provides pain relief and improves physical function and quality of life in patients with end-stage hip osteoarthritis. The incidence of hip replacement operations is expected to increase ...

    Authors: Signe Rosenlund, Leif Broeng, Carsten Jensen, Anders Holsgaard-Larsen and Søren Overgaard

    Citation: BMC Musculoskeletal Disorders 2014 15:354

    Content type: Study protocol

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  15. Intense physical activity (PA) improves muscle strength in children, but it remains uncertain whether moderately intense PA in a population-based cohort of children confers these benefits.

    Authors: Fredrik Detter, Jan-Åke Nilsson, Caroline Karlsson, Magnus Dencker, Björn E Rosengren and Magnus K Karlsson

    Citation: BMC Musculoskeletal Disorders 2014 15:353

    Content type: Research article

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  16. Subacromial impingement is a common cause of shoulder complaints in general practice. When the initial treatment with acetaminophen and low dose Non Steroidal Anti Inflammatory Drugs fails, triamcinolone aceto...

    Authors: Ludo IF Penning, Rob A de Bie and Geert HIM Walenkamp

    Citation: BMC Musculoskeletal Disorders 2014 15:352

    Content type: Research article

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  17. In arthroscopic surgery, the suture anchor technique has become popular for rotator cuff repair. Preoperative evaluation of the bone microstructure is of utmost importance because, especially in elderly patien...

    Authors: Yoshihiro Sakamoto, Akira Kido, Kazuya Inoue, Goro Sakurai, Tomohisa Hashiuchi, Mitsuru Munemoto and Yasuhito Tanaka

    Citation: BMC Musculoskeletal Disorders 2014 15:351

    Content type: Research article

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  18. Tissue engineering approaches for reconstruction of large bone defects are still technically immature, especially in regard to sufficient blood supply. Therefore, the aim of the present study was to investigat...

    Authors: Ulrich Lenze, Florian Pohlig, Sebastian Seitz, Christina Ern, Stefan Milz, Denitsa Docheva and Matthias Schieker

    Citation: BMC Musculoskeletal Disorders 2014 15:350

    Content type: Research article

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  19. Hirayama disease (HD), amyotrophic lateral sclerosis (ALS) or cervical spondylotic amyotrophy (CSA) may result in atrophy of intrinsic hand and forearm muscles. The incidence of HD is low, and it is rarely enc...

    Authors: Xiang Jin, Jian-Yuan Jiang, Fei-Zhou Lu, Xin-Lei Xia, Li-Xun Wang and Chao-Jun Zheng

    Citation: BMC Musculoskeletal Disorders 2014 15:349

    Content type: Research article

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  20. Lumbar spinal stenosis (LSS) is the common term used to describe patients with symptoms related to the anatomical reduction of the lumbar spinal canal size. However, some subjects may have a markedly narrowed ...

    Authors: Pekka Kuittinen, Petri Sipola, Tapani Saari, Timo Juhani Aalto, Sanna Sinikallio, Sakari Savolainen, Heikki Kröger, Veli Turunen, Ville Leinonen and Olavi Airaksinen

    Citation: BMC Musculoskeletal Disorders 2014 15:348

    Content type: Research article

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  21. The cn/cn dwarf mouse is caused by a loss-of-function mutation in the natriuretic peptide receptor 2 (NPR-2) gene which helps positively regulate endochondral longitudinal bone growth. The gene mutation corres...

    Authors: Frederic Shapiro, Lauren Barone, Andrew Johnson and Evelyn Flynn

    Citation: BMC Musculoskeletal Disorders 2014 15:347

    Content type: Research article

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  22. Previous studies have shown that the carpal tunnel syndrome seems to occur more frequently in patients with diabetes mellitus and might be associated with the duration of diabetes mellitus, microvascular compl...

    Authors: Steven H Hendriks, Peter R van Dijk, Klaas H Groenier, Peter Houpt, Henk JG Bilo and Nanne Kleefstra

    Citation: BMC Musculoskeletal Disorders 2014 15:346

    Content type: Research article

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  23. Active vitamin D metabolites have been shown to have protective effects in experimental arthritis especially when used as preventive treatment. However, because the direct effects of 1,25-dihydroxyvitamin D3 (...

    Authors: Peter Oelzner, Peter K Petrow, Gunter Wolf and Rolf Bräuer

    Citation: BMC Musculoskeletal Disorders 2014 15:345

    Content type: Research article

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  24. The purpose of this study was to document the clinical and radiographic results of a consecutive series of patients with ankylosing spondylitis (AS) who had undergone bilaterally primary THA using non-cemented...

    Authors: Wanchun Wang, Guoliang Huang, Tianlong Huang and Ren Wu

    Citation: BMC Musculoskeletal Disorders 2014 15:344

    Content type: Research article

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  25. Scoliogauge, has been developed for the measurement of ATR on iPhone smartphones. This study was to evaluate the reliability for the smartphone-aided ATR measurement method and to compare its reliability with ...

    Authors: Jun Qiao, Leilei Xu, Zezhang Zhu, Feng Zhu, Zhen Liu, Bangping Qian and Yong Qiu

    Citation: BMC Musculoskeletal Disorders 2014 15:343

    Content type: Research article

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  26. Lumbosacral radicular syndrome (LRS) is a self-limiting, benign, painful and impairing condition caused by lumbar disc herniation and inflammatory processes around the nerve root. Segmental epidural steroid in...

    Authors: Antje Spijker-Huiges, Jan C Winters, Marten van Wijhe and Klaas Groenier

    Citation: BMC Musculoskeletal Disorders 2014 15:341

    Content type: Research article

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  27. Recently, biological therapies for early intervention of degenerative disc disease have been introduced and developed; however, a functional animal model that mimics slowly progressive disc degeneration of hum...

    Authors: Fuxin Wei, Rui Zhong, Zhiyu Zhou, Le Wang, Ximin Pan, Shangbin Cui, Xuenong Zou, Manman Gao, Haixing Sun, Wenfang Chen and Shaoyu Liu

    Citation: BMC Musculoskeletal Disorders 2014 15:340

    Content type: Research article

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  28. Developmental dysplasia of the hip (DDH) always leads to cartilage degeneration and osteoarthritis of the hip joint. However, the diagnosis of early cartilage degeneration in DDH is still a clinical challenge....

    Authors: Ming Fu, Jin Liu, Guangxin Huang, Zhiyu Huang, Zhiqi Zhang, Peihui Wu, Bingjun Wang, Zibo Yang and Weiming Liao

    Citation: BMC Musculoskeletal Disorders 2014 15:339

    Content type: Research article

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  29. Knee flexion contractures prevent the full extension of the knee joint and cause disability. The etiology is not well defined. Extended periods of immobilization of joints lead to contractures difficult to com...

    Authors: Guy Trudel, Hans K Uhthoff, Louis Goudreau and Odette Laneuville

    Citation: BMC Musculoskeletal Disorders 2014 15:338

    Content type: Research article

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  30. Epidural fibrosis (EF) is a common complication after laminectomy. Salvianolic acid B (Sal B) is a major bioactive component of a traditional Chinese medical agent, Salvia miltiorrhiza, which has shown anti-infla...

    Authors: Feng Chen, Zhenbo Zuo, Kai Wang, Chengdong Zhang, Haifeng Gong, Fagang Ye, Aiyu Ji and Hao Tao

    Citation: BMC Musculoskeletal Disorders 2014 15:337

    Content type: Research article

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  31. The calcium-binding protein S100A12 correlates with measures of disease activity in patients with rheumatoid arthritis (RA). The protein reflects neutrophil activation and the present objective was to explore ...

    Authors: Hilde Haugedal Nordal, Johan G Brun, Anne-Kristine Halse, Roland Jonsson, Magne K Fagerhol and Hilde Berner Hammer

    Citation: BMC Musculoskeletal Disorders 2014 15:335

    Content type: Research article

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  32. The prevalence of osteoporosis is increasing and is a socio-economic burden worldwide. Although screening tests for osteoporosis in Korea are easily accessible, this condition remains undertreated. Evaluating ...

    Authors: Hyun-Young Shin, Hee Cheol Kang, Kiheon Lee and Sang Min Park

    Citation: BMC Musculoskeletal Disorders 2014 15:334

    Content type: Research article

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  33. Involvement of patients in decision-making about medication is currently being advocated. This study examined (the concordance between) inflammatory arthritis patients’ preferred and perceived involvement in d...

    Authors: Ingrid Nota, Constance HC Drossaert, Erik Taal, Harald E Vonkeman and Mart AFJ van de Laar

    Citation: BMC Musculoskeletal Disorders 2014 15:333

    Content type: Research article

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  34. Diagnosis and treatment decisions of cervical instability are made, in part, based on the clinician’s assessment of sagittal rotation on flexion and extension radiographs. The objective of this study is to eva...

    Authors: Sheng-Dan Jiang, Jiang-Wei Chen, Yue-Hua Yang, Xiao-Dong Chen and Lei-Sheng Jiang

    Citation: BMC Musculoskeletal Disorders 2014 15:332

    Content type: Research article

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  35. Subtrochanteric femoral shortening osteotomy is a crucial procedure to prevent nerve injury in total hip arthroplasty for severe developmental dysplasia of the hip. Transverse osteotomy was first applied, and ...

    Authors: Changchuan Li, Chi Zhang, Maolin Zhang and Yue Ding

    Citation: BMC Musculoskeletal Disorders 2014 15:331

    Content type: Research article

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  36. Aggressive curettage has been well established for the treatment of giant cell tumors (GCTs) of the bone. The purpose of this study was to review our experience and evaluate the role of different implant mater...

    Authors: Zhen-hua Gao, Jun-qiang Yin, Xian-biao Xie, Chang-ye Zou, Gang Huang, Jin wang and Jing-nan Shen

    Citation: BMC Musculoskeletal Disorders 2014 15:330

    Content type: Research article

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  37. The vacuum phenomenon within the intervertebral disc usually represents disc degeneration. There are no reports in the English literature that focus on the effect of an anterior vacuum disc on surgical outcome...

    Authors: Tung-Yi Lin, Jen-Chung Liao, Tsung-Ting Tsai, Meng-Ling Lu, Chi-Chien Niu, Wen-Jer Chen and Lih-Hui Chen

    Citation: BMC Musculoskeletal Disorders 2014 15:329

    Content type: Research article

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  38. Exercise related leg pain (ERLP) is a common lower limb overuse injury characterised by pain located between the knee and ankle that occurs during activity. The high incidence of the condition, subsequent inte...

    Authors: Melinda M Franettovich Smith, Sonia S Coates and Mark W Creaby

    Citation: BMC Musculoskeletal Disorders 2014 15:328

    Content type: Study protocol

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  39. Ankle-foot orthosis (AFO) is the most frequently used type of orthosis in children with cerebral palsy (CP). AFOs are designed either to improve function or to prevent or treat muscle contractures. The purpose...

    Authors: Maria Wingstrand, Gunnar Hägglund and Elisabet Rodby-Bousquet

    Citation: BMC Musculoskeletal Disorders 2014 15:327

    Content type: Research article

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  40. Large waist circumference is linked to poor health. Investigations of the relationship between waist circumference, as an index of abdominal fat, and bone mineral density (BMD) have yielded inconsistent result...

    Authors: Lian-Hua Cui, Min-Ho Shin, Sun-Seog Kweon, Jin-Su Choi, Jung-Ae Rhee, Young-Hoon Lee, Hae-Sung Nam, Seul-Ki Jeong, Kyeong-Soo Park, So-Yeon Ryu and Seong-Woo Choi

    Citation: BMC Musculoskeletal Disorders 2014 15:326

    Content type: Research article

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  41. The United States has the highest rate of lumbar spine surgery in the world, with rates increasing over 200% since 1990. Medicare spends over $1 billion annually on lumbar spine surgery. Despite surgical advan...

    Authors: Kristin R Archer, Rogelio A Coronado, Christine M Haug, Susan W Vanston, Clinton J Devin, Christopher J Fonnesbeck, Oran S Aaronson, Joseph S Cheng, Richard L Skolasky, Lee H Riley III and Stephen T Wegener

    Citation: BMC Musculoskeletal Disorders 2014 15:325

    Content type: Study protocol

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  42. Health Economists in Denmark have reported poor outcomes and low and delayed return to work for patients treated for Sub-Acromial Impingement syndrome (SAIS) by Arthroscopic Sub-Acromial Decompression (ASAD). ...

    Authors: Rahul Bhattacharyya, Kimberley Edwards and Angus W Wallace

    Citation: BMC Musculoskeletal Disorders 2014 15:324

    Content type: Research article

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  43. Treatment for displaced proximal humeral fractures is still under debate. Few studies exist at the highest level of evidence. Although reversed total shoulder prosthesis has gained popularity and showed promis...

    Authors: Tore Fjalestad, Petter Iversen, Margrethe Øye Hole, Morten Smedsrud and Jan Erik Madsen

    Citation: BMC Musculoskeletal Disorders 2014 15:323

    Content type: Study protocol

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  44. Osteoarthritis (OA) is a chronic disease, usually characterized by pain, which is associated with reduced muscle strength, disability and progressive loss of function. However, the pain influence over proprioc...

    Authors: Daniela C Silveira de Oliveira, Saulo Delfino Barboza, Franciele Dias da Costa, Monnique Ponciano Cabral, Vanessa Martins Pereira Silva and Valdeci Carlos Dionisio

    Citation: BMC Musculoskeletal Disorders 2014 15:321

    Content type: Research article

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  45. The precise etiology of knee osteoarthritis (KOA) pain remains highly controversial and there is no known effective treatment. Due to the known and suggested effects of neuropeptide Y (NPY) on pain, we have so...

    Authors: Lei Wang, Li Zhang, Haobo Pan, Songlin Peng, Minmin Lv and William Weijia Lu

    Citation: BMC Musculoskeletal Disorders 2014 15:319

    Content type: Research article

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