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  1. Hip osteoarthritis (OA) is a common condition leading to pain, disability and reduced quality of life. There is currently limited evidence to support the use of conservative, non-pharmacological treatments for...

    Authors: Kim L Bennell, Thorlene Egerton, Yong-Hao Pua, J Haxby Abbott, Kevin Sims, Ben Metcalf, Fiona McManus, Tim V Wrigley, Andrew Forbes, Anthony Harris and Rachelle Buchbinder
    Citation: BMC Musculoskeletal Disorders 2010 11:238
  2. Patients with incomplete recovery from obstetric brachial plexus injury (OBPI) usually develop secondary muscle imbalances and bone deformities at the shoulder joint. Considerable efforts have been made to cha...

    Authors: Rahul K Nath, Faiz Mahmooduddin, Xiaomei Liu, Melissa J Wentz and Andrea D Humphries
    Citation: BMC Musculoskeletal Disorders 2010 11:237
  3. Of all athletic knee injuries an anterior cruciate ligament (ACL) rupture results in the longest time loss from sport. Regardless of the therapy chosen, conservative or reconstructive, athletes are often force...

    Authors: Anne Benjaminse, Koen APM Lemmink, Ron L Diercks and Bert Otten
    Citation: BMC Musculoskeletal Disorders 2010 11:235
  4. Musculoskeletal pain in the low back and neck-shoulder regions is a major problem among the working population all over the world. The prevalence of musculoskeletal pain is found to be higher among women. Wome...

    Authors: Asbjørn T Binderup, Lars Arendt-Nielsen and Pascal Madeleine
    Citation: BMC Musculoskeletal Disorders 2010 11:234
  5. Degenerative musculoskeletal disorders are among the most frequent diseases occurring in adulthood, often impairing patients' functional mobility and physical activity. The aim of the present study was to inve...

    Authors: Corinna C Winter, Mirko Brandes, Carsten Müller, Tim Schubert, Michael Ringling, Axel Hillmann, Dieter Rosenbaum and Tobias L Schulte
    Citation: BMC Musculoskeletal Disorders 2010 11:233
  6. There are no proven therapies that modify the structural changes associated with osteoarthritis (OA). Preclinical data suggests that intra-articular recombinant human BMP-7 (bone morphogenetic protein-7) has r...

    Authors: David J Hunter, Marilyn C Pike, Beth L Jonas, Eugene Kissin, Julie Krop and Tim McAlindon
    Citation: BMC Musculoskeletal Disorders 2010 11:232
  7. Differing levels of tendon retraction are found in full-thickness rotator cuff tears. The pathophysiology of tendon degeneration and retraction is unclear. Neoangiogenesis in tendon parenchyma indicates degene...

    Authors: Stefan Lakemeier, Johannes JA Reichelt, Thilo Patzer, Susanne Fuchs-Winkelmann, Juergen RJ Paletta and Markus D Schofer
    Citation: BMC Musculoskeletal Disorders 2010 11:230
  8. We compared the healing response of tibial delayed unions between subjects treated with low-intensity pulsed ultrasound (LIPUS) (n = 51) and subjects treated with a sham device (n = 50). Fracture age was ≥ 4 m...

    Authors: Markus D Schofer, Jon E Block, Julia Aigner and Andreas Schmelz
    Citation: BMC Musculoskeletal Disorders 2010 11:229
  9. Surgery for type II SLAP (superior labral anterior posterior) lesions of the shoulder is a promising but unproven treatment. The procedures include labral repair or biceps tenodesis. Retrospective cohort studi...

    Authors: Øystein Skare, Cecilie Piene Schrøder, Olav Reikerås, Petter Mowinckel and Jens Ivar Brox
    Citation: BMC Musculoskeletal Disorders 2010 11:228
  10. Recent studies suggest that there is a learning curve for metal-on-metal hip resurfacing. The purpose of this study was to assess whether implant positioning changed with surgeon experience and whether positio...

    Authors: David R Marker, Michael G Zywiel, Aaron J Johnson, Thorsten M Seyler and Michael A Mont
    Citation: BMC Musculoskeletal Disorders 2010 11:227
  11. The long-term effect of hip fracture on health-related quality of life (HRQOL) and global quality of life (GQOL) has not been thoroughly studied in prospective case-control studies.

    Authors: Gudrun Rohde, Glenn Haugeberg, Anne Marit Mengshoel, Torbjorn Moum and Astrid K Wahl
    Citation: BMC Musculoskeletal Disorders 2010 11:226
  12. The effects of intervention programs on health-related quality of life (HRQOL) of patients with hip fracture have not been well studied. We hypothesized that older patients with hip fracture who received our i...

    Authors: Yea-Ing L Shyu, Jersey Liang, Chi-Chuan Wu, Huey-Shinn Cheng and Min-Chi Chen
    Citation: BMC Musculoskeletal Disorders 2010 11:225
  13. In addition to general health and pain, sleep is highly relevant to judging the well-being of an individual. Of these three important outcome variables, however, sleep is neglected in most outcome studies.

    Authors: Emin Aghayev, Haiko Sprott, Dieter Bohler, Christoph Röder and Urs Müller
    Citation: BMC Musculoskeletal Disorders 2010 11:224
  14. To investigate the association between myositis autoantibodies and clinical subsets of inflammatory myositis in Korean patients.

    Authors: Eun Ha Kang, Ran Nakashima, Tsuneyo Mimori, Jinhyun Kim, Yun Jong Lee, Eun Bong Lee and Yeong Wook Song
    Citation: BMC Musculoskeletal Disorders 2010 11:223
  15. Assessment of sensorimotor function is useful for classification and treatment evaluation of neck pain disorders. Several studies have investigated various aspects of cervical motor functions. Most of these ha...

    Authors: Ulrik Röijezon, Mats Djupsjöbacka, Martin Björklund, Charlotte Häger-Ross, Helena Grip and Dario G Liebermann
    Citation: BMC Musculoskeletal Disorders 2010 11:222
  16. The anti-human Fas/APO-1/CD95 (Fas) mouse/human chimeric monoclonal IgM antibody ARG098 (ARG098) targets the human Fas molecule. The cytotoxic effects of ARG098 on cells isolated from RA patients, on normal ce...

    Authors: Noriko Odani-Kawabata, Miwa Takai-Imamura, Osamu Katsuta, Hiroshi Nakamura, Kusuki Nishioka, Keiko Funahashi, Tsukasa Matsubara, Minoru Sasano and Hiroyuki Aono
    Citation: BMC Musculoskeletal Disorders 2010 11:221
  17. Current research aims to develop innovative approaches to improve chondral and osteochondral regeneration. The objective of this study was to investigate the regenerative potential of platelet-rich plasma (PRP...

    Authors: Elizaveta Kon, Giuseppe Filardo, Marco Delcogliano, Milena Fini, Francesca Salamanna, Gianluca Giavaresi, Ivan Martin and Maurilio Marcacci
    Citation: BMC Musculoskeletal Disorders 2010 11:220
  18. The effectiveness of bracing on preventing curve progression in coronal plane for mild and moderate adolescent idiopathic scoliosis (AIS) patients has been confirmed by previous radiographic researches. Howeve...

    Authors: Jun Jiang, Yong Qiu, Saihu Mao, Qinghua Zhao, Bangping Qian and Feng Zhu
    Citation: BMC Musculoskeletal Disorders 2010 11:219
  19. Shoulder pain is a common complaint in primary health care and has an unfavourable outcome in many patients. The objectives were to identify predictors for pain and disability (SPADI) and work status in patien...

    Authors: Kaia Engebretsen, Margreth Grotle, Erik Bautz-Holter, Ole Marius Ekeberg and Jens Ivar Brox
    Citation: BMC Musculoskeletal Disorders 2010 11:218
  20. Many patients who receive steroid pulse therapy go home the same day or the day after steroid administration. Nursing instructions are important for improving patient knowledge related to their diseases and tr...

    Authors: Yu-Chu Pai
    Citation: BMC Musculoskeletal Disorders 2010 11:217
  21. Fatigue is increasingly recognized as an important symptom in fibromyalgia (FM). Unknown however is how fatigue is experienced by individuals in the context of FM. We conducted qualitative research in order to...

    Authors: Louise Humphrey, Rob Arbuckle, Philip Mease, David A Williams, Bente Danneskiold Samsoe and Claire Gilbert
    Citation: BMC Musculoskeletal Disorders 2010 11:216
  22. Hallux valgus (HV) is a common condition involving the progressive subluxation of the first metatarsophalangeal joint due to lateral deviation of the hallux and medial deviation of the first metatarsal. The ob...

    Authors: Hylton B Menz, Mohammad R Fotoohabadi, Elin Wee and Martin J Spink
    Citation: BMC Musculoskeletal Disorders 2010 11:215
  23. The quadriceps femoris muscle ruptures usually occur in the middle-aged population. We present a 4-year-old patient with partial rupture of the quadriceps femoris muscle. To our knowledge, this is the youngest...

    Authors: Gokhan Aydemir, Selami Cakmak and Secil Aydinoz
    Citation: BMC Musculoskeletal Disorders 2010 11:214
  24. Total joint replacement (TJR) of the hip or knee for osteoarthritis is among the most common elective surgical procedures. There is some inequity in provision of TJR. How decisions are made about who will have...

    Authors: Rachael Gooberman-Hill, Anna Sansom, Caroline M Sanders, Paul A Dieppe, Jeremy Horwood, Ian D Learmonth, Susan Williams and Jenny L Donovan
    Citation: BMC Musculoskeletal Disorders 2010 11:213
  25. In the treatment of chronic back pain, cognitive methods are attracting increased attention due to evidence of effectiveness similar to that of traditional therapies. The purpose of this study was to compare t...

    Authors: Pia H Sorensen, Tom Bendix, Claus Manniche, Lars Korsholm, Dorte Lemvigh and Aage Indahl
    Citation: BMC Musculoskeletal Disorders 2010 11:212
  26. The Wnt/β-catenin pathway is a major signaling cascade in bone biology, playing a key role in bone development and remodeling. The objectives of this study were firstly, to determine the effects of dexamethaso...

    Authors: Joseph S Butler, Joseph M Queally, Brian M Devitt, David W Murray, Peter P Doran and John M O'Byrne
    Citation: BMC Musculoskeletal Disorders 2010 11:210
  27. Interleukin (IL)-17 is an important factor in rheumatoid arthritis (RA) pathogenesis. MicroRNA (miRNA)s are a family of non coding RNAs and associated with human diseases including RA. The purpose of this stud...

    Authors: Takuya Niimoto, Tomoyuki Nakasa, Masakazu Ishikawa, Atsushi Okuhara, Bunichiro Izumi, Masataka Deie, Osami Suzuki, Nobuo Adachi and Mitsuo Ochi
    Citation: BMC Musculoskeletal Disorders 2010 11:209
  28. Though sera are essential for Mesenchymal stem cells (MSCs), the effect of heat-inactivation remains unknown. Autologous human serum is recommended for clinical use; however, it is unclear whether differentiat...

    Authors: Akimoto Nimura, Takeshi Muneta, Koji Otabe, Hideyuki Koga, Young-Jin Ju, Tomoyuki Mochizuki, Koji Suzuki and Ichiro Sekiya
    Citation: BMC Musculoskeletal Disorders 2010 11:208
  29. High tibial osteotomy (HTO) is a well established technique for the treatment of medial osteoarthritis of the knee with varus malalignment. Results of total knee arthroplasty (TKA) after previous HTO are still...

    Authors: Turgay Efe, Thomas J Heyse, Christoph Boese, Nina Timmesfeld, Susanne Fuchs-Winkelmann, Jan Schmitt, Christina Theisen and Markus D Schofer
    Citation: BMC Musculoskeletal Disorders 2010 11:207
  30. Chronic back pain is a significant problem worldwide and may be especially prevalent among patients receiving care in the U.S. Department of Veterans Affairs healthcare system. Back pain affects adults at all ...

    Authors: Sarah L Krein, Tabitha Metreger, Reema Kadri, Maria Hughes, Eve A Kerr, John D Piette, Hyungjin Myra Kim and Caroline R Richardson
    Citation: BMC Musculoskeletal Disorders 2010 11:205
  31. Despite its frequent use as a hypnotic, trazodone has not been systematically assessed in fibromyalgia patients. In the present study have we evaluated the potential effectiveness and tolerability of trazodone...

    Authors: Piedad Morillas-Arques, Carmen Ma Rodriguez-Lopez, Rocio Molina-Barea, Fernando Rico-Villademoros and Elena P Calandre
    Citation: BMC Musculoskeletal Disorders 2010 11:204
  32. This is the first longitudinal study with a 22-year follow-up, based on a national and complete sample, to determine whether the prevalence of hip fracture and the age when it occurs are influenced by migratio...

    Authors: Björn Albin, Katarina Hjelm and Sölve Elmståhl
    Citation: BMC Musculoskeletal Disorders 2010 11:203
  33. Detection of nerve involvement originating in the spine is a primary concern in the assessment of spine symptoms. Magnetic resonance imaging (MRI) has become the diagnostic method of choice for this detection....

    Authors: Bo C Bertilson, Eva Brosjö, Hans Billing and Lars-Erik Strender
    Citation: BMC Musculoskeletal Disorders 2010 11:202
  34. Patellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle and older age, but its relation to PF disorders and symptoms earlier in life is unclear. Our aim was to conduct a systematic review to...

    Authors: Martin J Thomas, Laurence Wood, James Selfe and George Peat
    Citation: BMC Musculoskeletal Disorders 2010 11:201
  35. Shoulder complaints are common in primary care and have unfavourable long term prognosis. Our objective was to evaluate the clinical effectiveness of manipulative therapy of the cervicothoracic spine and the a...

    Authors: Gert JD Bergman, Jan C Winter, Maurits W van Tulder, Betty Meyboom-de Jong, Klaas Postema and Geert JMG van der Heijden
    Citation: BMC Musculoskeletal Disorders 2010 11:200
  36. Because of the implant-related problems with pedicle screw-based spinal instrumentations, other types of fixation have been tried in spinal arthrodesis. One such technique is the direct trans-pedicular, trans-...

    Authors: Christof Birkenmaier, Olaf Suess, Michael Pfeiffer, Ralf Burger, Kirsten Schmieder and Bernd Wegener
    Citation: BMC Musculoskeletal Disorders 2010 11:199
  37. Submaximal exercise is used in the management of muscular dystrophy. The effects of mechanical stimulation on skeletal development are well understood, although its effects on cartilage growth have yet to be i...

    Authors: David J Nye, Jeffrey M Costas, Jessica B Henley, Jin-Kwang Kim and Jeffrey H Plochocki
    Citation: BMC Musculoskeletal Disorders 2010 11:198
  38. To develop a population-based cohort of people with ankylosing spondylitis (AS) in Wales using (1) secondary care clinical datasets, (2) patient-derived questionnaire data and (3) routinely-collected informati...

    Authors: Mark D Atkinson, Sinead Brophy, Stefan Siebert, Mike B Gravenor, Ceri Phillips, David V Ford, Kerina H Jones and Ronan A Lyons
    Citation: BMC Musculoskeletal Disorders 2010 11:197
  39. Distance running is a popular recreational exercise. It is a beneficial activity for health and well being. However, running may also cause injuries, especially of the lower extremities. In literature there is...

    Authors: Steef W Bredeweg, Sjouke Zijlstra and Ida Buist
    Citation: BMC Musculoskeletal Disorders 2010 11:196
  40. Weight-bearing and high intensity physical activities are particularly beneficial for stimulating bone growth in children given that bone responds favorably to mechanical load. While it is important to assess ...

    Authors: Christina D Economos, Erin Hennessy, Jennifer M Sacheck, M Kyla Shea and Elena N Naumova
    Citation: BMC Musculoskeletal Disorders 2010 11:195
  41. The aims of this study were to evaluate the construct validity (known group), concurrent validity (criterion based) and test-retest (intra-rater) reliability of manual goniometers to measure passive hip range ...

    Authors: Silvio Nussbaumer, Michael Leunig, Julia F Glatthorn, Simone Stauffacher, Hans Gerber and Nicola A Maffiuletti
    Citation: BMC Musculoskeletal Disorders 2010 11:194
  42. Many authors have reported about the high prevalence rates of self-reported back pain in children. Nevertheless, little is known about the diagnosis of back disorders - regardless of whether the diagnosis is a...

    Authors: Elke B Ochsmann, Carlos L Escobar Pinzón, Stephan Letzel, Thomas Kraus, Martina Michaelis and Eva Muenster
    Citation: BMC Musculoskeletal Disorders 2010 11:193
  43. Rheumatoid Arthritis (RA) is a chronic autoimmune inflammatory disorder. Although the pathogenesis of disease is unclear, it is well known that T cells play a major role in both development and perpetuation of...

    Authors: Atil Bisgin, Ender Terzioglu, Cigdem Aydin, Burcak Yoldas, Veli Yazisiz, Nilufer Balci, Huseyin Bagci, Reginald M Gorczynski, Cezmi A Akdis and Salih Sanlioglu
    Citation: BMC Musculoskeletal Disorders 2010 11:192
  44. Long head biceps (LHB) degeneration in combination with rotator cuff tears can be a source of chronic shoulder pain. LHB tenotomy is an approved surgical procedure for pain reduction and improvement of joint f...

    Authors: Stefan Lakemeier, Johannes JA Reichelt, Nina Timmesfeld, Susanne Fuchs-Winkelmann, Juergen RJ Paletta and Markus D Schofer
    Citation: BMC Musculoskeletal Disorders 2010 11:191
  45. Low back pain commonly affects work ability, but little is known about the work-related help and advice that patients receive from GPs and other clinicians. The purpose of this study was to explore the experie...

    Authors: Carol Coole, Paul J Watson and Avril Drummond
    Citation: BMC Musculoskeletal Disorders 2010 11:190
  46. Disc degeneration is characterized by a loss of cellularity, degradation of the extracellular matrix, and, as a result, morphological changes and biomechanical alterations. We hypothesized that the distributio...

    Authors: Delphine Périé and Daniel Curnier
    Citation: BMC Musculoskeletal Disorders 2010 11:189

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