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  1. Little is known about the relationships of circulating levels of biomarkers of cartilage degradation with biomechanical outcomes relevant to knee osteoarthritis (OA) or biomarker changes following non-pharmaco...

    Authors: Michael A Hunt, Courtney L Pollock, Virginia Byers Kraus, Tore Saxne, Sue Peters, Janet L Huebner, Eric C Sayre and Jolanda Cibere
    Citation: BMC Musculoskeletal Disorders 2013 14:115
  2. The risk of experiencing an osteoporotic fracture is greater for adults with type 2 diabetes despite higher than normal bone mineral density (BMD). In addition to BMD, trabecular bone microarchitecture contrib...

    Authors: Janet M Pritchard, Lora M Giangregorio, Stephanie A Atkinson, Karen A Beattie, Dean Inglis, George Ioannidis, Hertzel Gerstein, Zubin Punthakee, Jonathan D Adachi and Alexandra Papaioannou
    Citation: BMC Musculoskeletal Disorders 2013 14:114
  3. Studies have shown that ischemia-reperfusion (I/R) produces free radicals leading to lipid peroxidation and damage to skeletal muscle. The purposes of this study were 1) to assess the histological findings of ...

    Authors: Kazuichiro Hori, Masaya Tsujii, Takahiro Iino, Haruhiko Satonaka, Takeshi Uemura, Koji Akeda, Masahiro Hasegawa, Atsumasa Uchida and Akihiro Sudo
    Citation: BMC Musculoskeletal Disorders 2013 14:113
  4. Recent case–control studies have shown an association between type 3 finger length pattern (longer ring finger than index finger) and knee osteoarthritis. This large cross-sectional study tests the hypothesis ...

    Authors: Kristin Sigurjonsdottir, Thorir M Bjorgulfsson, Thor Aspelund, Gudny Eiriksdottir, Sigurdur Sigurdsson, Thorvaldur Ingvarsson, Tamara B Harris, Lenore Launer, Vilmundur Gudnason and Helgi Jonsson
    Citation: BMC Musculoskeletal Disorders 2013 14:112
  5. The acute ankle sprain is one of the most common injuries seen in trauma departments. Ankle sprains have an incidence of about one injury per 10 000 people a day. In contrast tarsal coalition is a rare conditi...

    Authors: Dirk Wähnert, Niklas Grüneweller, Julia Evers, Anna C Sellmeier, Michael J Raschke and Sabine Ochman
    Citation: BMC Musculoskeletal Disorders 2013 14:111
  6. High tibial osteotomy (HTO) with a medial opening wedge has been used to treat medial compartment osteoarthritis. However, this makes the proximal tibia a highly unstable structure and causes plate and screws ...

    Authors: Chu-An Luo, Shi-Yuan Hua, Shang-Chih Lin, Chun-Ming Chen and Ching-Shiow Tseng
    Citation: BMC Musculoskeletal Disorders 2013 14:110
  7. Anterior cruciate ligament reconstruction (ACLR) is standard practice for athletes that wish to return to high-level activities; however functional outcomes after ACLR are poor. Quadriceps strength weakness, a...

    Authors: Kathleen White, Stephanie L Di Stasi, Angela H Smith and Lynn Snyder-Mackler
    Citation: BMC Musculoskeletal Disorders 2013 14:108
  8. The Hueter-Volkmann law describes growth principles around joints and joint deformation. It states that decreased stress leads to increased growth and that excessive stress leads to growth retardation. Aim of ...

    Authors: Valerie M van Gelein Vitringa, Barend J van Royen and Johannes A van der Sluijs
    Citation: BMC Musculoskeletal Disorders 2013 14:107
  9. Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance i...

    Authors: Henrik Gudbergsen, Mikael Boesen, Robin Christensen, Else Marie Bartels, Marius Henriksen, Bente Danneskiold-Samsøe and Henning Bliddal
    Citation: BMC Musculoskeletal Disorders 2013 14:106
  10. Inflammatory and matrix degrading gene variants have been reported to be associated with disc degeneration. Some of these variants also modulate peripheral pain. This study examines the association of these ge...

    Authors: Ahmad Omair, Marit Holden, Benedicte Alexandra Lie, Olav Reikeras and Jens Ivar Brox
    Citation: BMC Musculoskeletal Disorders 2013 14:105
  11. Ankle strength is often impaired in some of the most common neuromuscular disorders. Consequently, strength generated around this joint is important to assess, because it has a great impact on balance and gait...

    Authors: Amélie Moraux, Aurélie Canal, Gwenn Ollivier, Isabelle Ledoux, Valérie Doppler, Christine Payan and Jean-Yves Hogrel
    Citation: BMC Musculoskeletal Disorders 2013 14:104
  12. Tibial shaft fractures are the most common long bone fracture and are prone to complications such as nonunion requiring reoperations to promote fracture healing. We aimed to determine the fracture characterist...

    Authors: Katie Fong, Victoria Truong, Clary J Foote, Brad Petrisor, Dale Williams, Bill Ristevski, Sheila Sprague and Mohit Bhandari
    Citation: BMC Musculoskeletal Disorders 2013 14:103
  13. The purpose of this study was to evaluate the role of medial support and clinical factors responsible on outcomes and major complications associated with treatment of unstable proximal humerus fractures using ...

    Authors: Woo-Bin Jung, Eun-Sun Moon, Sung-Kyu Kim, David Kovacevic and Myung-Sun Kim
    Citation: BMC Musculoskeletal Disorders 2013 14:102
  14. Psoriatic Arthritis (PsA) is estimated to occur in 10-15% of people with psoriasis and accounts for 13% of people attending early arthritis clinics. With an increasing awareness of the poor outcomes associated...

    Authors: Laura C Coates, Nuria Navarro-Coy, Sarah R Brown, Sarah Brown, Lucy McParland, Howard Collier, Emma Skinner, Jennifer Law, Anna Moverley, Sue Pavitt, Claire Hulme, Paul Emery, Philip G Conaghan and Philip S Helliwell
    Citation: BMC Musculoskeletal Disorders 2013 14:101
  15. The editors of BMC Musculoskeletal Disorders would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).

    Authors: Tim Shipley
    Citation: BMC Musculoskeletal Disorders 2013 14:80
  16. Musculoskeletal pain (MSP) is one of the most frequent causes of sick leave from work, and is a common and potentially disabling condition. This study is based on the salutogenic perspective and investigates t...

    Authors: Heidi Sivertsen, Monica Lillefjell and Geir Arild Espnes
    Citation: BMC Musculoskeletal Disorders 2013 14:100
  17. Clinical activity of ankylosing spondylitis (AS) predicts the natural course of the disease and the response to treatment. Several molecules are involved in new bone formation resulting in structural damage in...

    Authors: Mariusz Korkosz, Jerzy Gąsowski, Piotr Leszczyński, Katarzyna Pawlak-Buś, Sławomir Jeka, Ewa Kucharska and Tomasz Grodzicki
    Citation: BMC Musculoskeletal Disorders 2013 14:99
  18. Australian professional orchestral musicians reported a lifetime prevalence of musculoskeletal injuries that had interfered with playing at 84%. Physical therapy-led triage clinics may be a practical method to...

    Authors: Cliffton Chan, Tim Driscoll and Bronwen Ackermann
    Citation: BMC Musculoskeletal Disorders 2013 14:98
  19. Muscle activity and pain development of fibromyalgia (FM) patients in response to mental stress show inconsistent results, when compared to healthy controls (HCs). A possible reason for the inconsistent result...

    Authors: Rolf Harald Westgaard, Paul Jarle Mork, Håvard Wuttudal Lorås, Roberto Riva and Ulf Lundberg
    Citation: BMC Musculoskeletal Disorders 2013 14:97
  20. Manufacturers of implants and materials in the field of orthopaedics use significant amounts of funding to produce informational material to influence the decision-making process of orthopaedic surgeons with r...

    Authors: Arndt P Schulz, Anders Jönsson, Richard Kasch, Prithee Jettoo and Mohit Bhandari
    Citation: BMC Musculoskeletal Disorders 2013 14:96
  21. Complex foot and ankle fractures, such as calcaneum fractures or Lisfranc dislocations, are often associated with a poor outcome, especially in terms of gait capacity. Indeed, degenerative changes often lead t...

    Authors: Philippe Terrier, François Luthi and Olivier Dériaz
    Citation: BMC Musculoskeletal Disorders 2013 14:94
  22. Musculoskeletal disorders account for one third of the long-term absenteeism in Denmark and the number of individuals sick listed for more than four weeks is increasing. Compared to other diagnoses, patients w...

    Authors: Annette Fisker, Henning Langberg, Tom Petersen and Ole Steen Mortensen
    Citation: BMC Musculoskeletal Disorders 2013 14:93
  23. Low back pain (LBP) is one of the most frequent musculoskeletal conditions in industrialized countries and its economic impact is important. Spinal manipulation therapy (SMT) is believed to be a valid approach...

    Authors: Marie-Pierre Harvey and Martin Descarreaux
    Citation: BMC Musculoskeletal Disorders 2013 14:92
  24. There is evidence of prolonged poor function in patients following total hip replacement (THR). Studies of progressive resistance training (PRT) interventions to improve function are often compared to ‘standar...

    Authors: Tosan Okoro, Ashok Ramavath, Jan Howarth, Jane Jenkinson, Peter Maddison, John G Andrew and Andrew Lemmey
    Citation: BMC Musculoskeletal Disorders 2013 14:91
  25. The purpose of this study was to investigate whether uphill treadmill running in rats created histopathological changes within the Achilles tendon consistent with Achilles tendinosis in humans.

    Authors: Rachel C Dirks, Jeffrey S Richard, Angela M Fearon, Alexander Scott, Lauren G Koch, Steven L Britton and Stuart J Warden
    Citation: BMC Musculoskeletal Disorders 2013 14:90
  26. In Germany, a multidisciplinary rehabilitation named “behavioural medical rehabilitation” (BMR) is available for treatment of chronic low back pain (clbp). A central component of BMR is standard exercise thera...

    Authors: Jana Hofmann, Stefan Peters, Wolfgang Geidl, Christian Hentschke and Klaus Pfeifer
    Citation: BMC Musculoskeletal Disorders 2013 14:89
  27. Injury among soccer referees is rarely studied, especially with regard to differences in the quality level of the refereeing. Additionally, we have found no study that has reported injury occurrence during off...

    Authors: Goran Gabrilo, Marko Ostojic, Kemal Idrizovic, Bozidar Novosel and Damir Sekulic
    Citation: BMC Musculoskeletal Disorders 2013 14:88
  28. The role of environmental factors in lumbar intervertebral disc degeneration (DD) in young adults is largely unknown. Therefore, we investigated whether body mass index (BMI), smoking, and physical activity ar...

    Authors: Jani Takatalo, Jaro Karppinen, Simo Taimela, Jaakko Niinimäki, Jaana Laitinen, Roberto Blanco Sequeiros, Markus Paananen, Jouko Remes, Simo Näyhä, Tuija Tammelin, Raija Korpelainen and Osmo Tervonen
    Citation: BMC Musculoskeletal Disorders 2013 14:87
  29. The role of physical fitness (VO2Max (mlO2*min-1*kg-1)) as a risk factor for herniated lumbar disc disease (HLDD) is unknown. The objective of this study was to examine the association between aerobic (physical) ...

    Authors: Marie B Jørgensen, Andreas Holtermann, Finn Gyntelberg and Poul Suadicani
    Citation: BMC Musculoskeletal Disorders 2013 14:86
  30. The single nucleotide polymorphism (SNP) rs2615977 is associated with osteoarthritis (OA) and is located in intron 31 of COL11A1, a strong candidate gene for this degenerative musculoskeletal disease. Furthermore...

    Authors: Emma V A Raine, Andrew W Dodd, Louise N Reynard and John Loughlin
    Citation: BMC Musculoskeletal Disorders 2013 14:85
  31. Few prospective cohort studies of workplace low back pain (LBP) with quantified job physical exposure have been performed. There are few prospective epidemiological studies for LBP occupational risk factors an...

    Authors: Arun Garg, Kurt T Hegmann, J Steven Moore, Jay Kapellusch, Matthew S Thiese, Sruthi Boda, Parag Bhoyr, Donald Bloswick, Andrew Merryweather, Richard Sesek, Gwen Deckow-Schaefer, James Foster, Eric Wood, Xiaoming Sheng and Richard Holubkov
    Citation: BMC Musculoskeletal Disorders 2013 14:84
  32. Health status is an important predictor of patient outcomes. Consequently, identifying patient predictors of health status is essential. In musculoskeletal orthopaedic care, the majority of work examining the ...

    Authors: Anthony V Perruccio, Rajiv Gandhi and Y Raja Rampersaud
    Citation: BMC Musculoskeletal Disorders 2013 14:83
  33. Symptoms associated with osteoarthritis of the knee result in decreased function, loss of working capacity and extensive social and medical costs. There is a need to investigate and develop effective intervent...

    Authors: Benjamin Waller, Matti Munukka, Juhani Multanen, Timo Rantalainen, Tapani Pöyhönen, Miika T Nieminen, Ilkka Kiviranta, Hannu Kautiainen, Harri Selänne, Joost Dekker, Sarianna Sipilä, Urho M Kujala, Arja Häkkinen and Ari Heinonen
    Citation: BMC Musculoskeletal Disorders 2013 14:82
  34. Bone density measurements by DXA are not feasible for large population studies, whereas portable ultrasound heel scanners can provide a practical way of assessing bone health status. The purpose of this study ...

    Authors: Marlena C Kruger, Joanne M Todd, Linda M Schollum, Barbara Kuhn-Sherlock, Drew W McLean and Kim Wylie
    Citation: BMC Musculoskeletal Disorders 2013 14:81
  35. To investigate hand bone loss (HBL) measured by digital X-ray radiogrammetry (DXR) in patients with early rheumatoid arthritis (RA) receiving different treatment regimens, and to evaluate if DXR change rates d...

    Authors: Hamed Rezaei, Saedis Saevarsdottir, Pierre Geborek, Ingemar F Petersson, Ronald F van Vollenhoven and Kristina Forslind
    Citation: BMC Musculoskeletal Disorders 2013 14:79
  36. Hypovitaminosis D has previously been reported in both the general population, in people with chronic musculoskeletal pain, and in people with low back pain (LBP). Myopathy-related symptoms such as diffuse bon...

    Authors: Jannick Vaaben Johansen, Claus Manniche and Per Kjaer
    Citation: BMC Musculoskeletal Disorders 2013 14:78
  37. The purpose of this paper was to review the literature of the cohort studies which evaluated the association between physical activity during the life course and bone mineral content or density in young adults.

    Authors: Renata M Bielemann, Jeovany Martinez-Mesa and Denise Petrucci Gigante
    Citation: BMC Musculoskeletal Disorders 2013 14:77
  38. Bone is a slowly regenerating tissue influenced by various physiological processes, including proliferation, differentiation, and angiogenesis, under the control of growth factors. Shortening this healing time...

    Authors: Yin-gang Zhang, Zhi Yang, Hong Zhang, Miao Liu, Yushen Qiu and Xiong Guo
    Citation: BMC Musculoskeletal Disorders 2013 14:76
  39. Osteoporotic vertebral compression fracture is the leading cause of disability and morbidity in elderly people. Treatment of this condition remains a challenge. Osteoporotic vertebral compression fractures can...

    Authors: Jui-Yang Hsieh, Chung-Ding Wu, Ting-Ming Wang, Hsuan-Yu Chen, Chui-Jia Farn and Po-Quang Chen
    Citation: BMC Musculoskeletal Disorders 2013 14:75
  40. Intramedullary nailing is a standard surgical procedure for fixation of proximal femoral fractures, but is associated with considerable radiation exposure for controlling the implant placement, due to the perc...

    Authors: A Wilharm, I Marintschev, G O Hofmann and F Gras
    Citation: BMC Musculoskeletal Disorders 2013 14:74
  41. Shoulder pain is a common condition with prevalence estimates of 7–26% and the associated disability is multi-faceted. For functional assessments in clinic and research, a number of condition-specific and gene...

    Authors: Yngve Roe, Helene Lundegaard Soberg, Erik Bautz-Holter and Sigrid Ostensjo
    Citation: BMC Musculoskeletal Disorders 2013 14:73
  42. Assessment of shoulder mobility is essential for diagnosis and clinical follow-up of shoulder diseases. Only a few highly sophisticated instruments for objective measurements of shoulder mobility are available...

    Authors: Bilal Farouk El-Zayat, Turgay Efe, Annett Heidrich, Robert Anetsmann, Nina Timmesfeld, Susanne Fuchs-Winkelmann and Markus Dietmar Schofer
    Citation: BMC Musculoskeletal Disorders 2013 14:72
  43. Arthroscopic partial meniscectomy has been shown to be of no benefit to patients with concomitant knee osteoarthritis, but the optimal treatment of a degenerative meniscus tear in patients with mild or no knee...

    Authors: Kristoffer B Hare, L Stefan Lohmander, Robin Christensen and Ewa M Roos
    Citation: BMC Musculoskeletal Disorders 2013 14:71
  44. Despite the prominence of hip fractures in orthopedic trauma, the assessment of fracture healing using radiographs remains subjective. The variability in the assessment of fracture healing has important implic...

    Authors: Mohit Bhandari, Mary M Chiavaras, Naveen Parasu, Hema Choudur, Olufemi Ayeni, Rajesh Chakravertty, Simrit Bains, Alisha Hak, Sheila Sprague and Brad Petrisor
    Citation: BMC Musculoskeletal Disorders 2013 14:70
  45. Desmoid tumor is a rare type of cancer that develops in the tissues that form tendons and ligaments. These tumors, also called aggressive fibromatosis, are considered benign with no metastatic potential. They ...

    Authors: Wang Ling, Song Kedong, Wang Hong, Zhang Weiguo and Lv Decheng
    Citation: BMC Musculoskeletal Disorders 2013 14:69
  46. Currently it is uncertain how to define osteoporosis and who to treat after a hip fracture. There is little to support the universal treatment of all such patients but how to select those most in need of treat...

    Authors: Richard G Crilly and Lizebeth Cox
    Citation: BMC Musculoskeletal Disorders 2013 14:68
  47. The prevalence of musculoskeletal pain in the shoulder, arm and hand is high among slaughterhouse workers, allegedly due to the highly repetitive and forceful exposure of these body regions during work. Work d...

    Authors: Emil Sundstrup, Markus D Jakobsen, Christoffer H Andersen, Kenneth Jay, Roger Persson, Per Aagaard and Lars L Andersen
    Citation: BMC Musculoskeletal Disorders 2013 14:67
  48. In the last years intramedullary nailing has become the treatment of choice for most displaced diaphyseal tibia fractures. In contrast intramedullary nailing of distal tibia fractures is accompanied by problem...

    Authors: Dirk Wähnert, Yves Stolarczyk, Konrad L Hoffmeier, Michael J Raschke, Gunther O Hofmann and Thomas Mückley
    Citation: BMC Musculoskeletal Disorders 2013 14:66
  49. Deep venous thrombosis (DVT) or pulmonary embolism (PE) is a rare, but not exceptional presentation of soft tissue sarcomas (STSs). Due to the remarkable difference in the incidence between DVT or PE and STSs,...

    Authors: Carlo Perisano, Nicola Maffulli, Pamela Colelli, Emanuele Marzetti, Alfredo Schiavone Panni and Giulio Maccauro
    Citation: BMC Musculoskeletal Disorders 2013 14:64

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