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  1. Exercise therapy in patients with hip and/or knee osteoarthritis is effective in reducing pain, increasing physical activity and physical functioning, but costly and a burden for the health care budget. A web-...

    Authors: Corelien JJ Kloek, Daniël Bossen, Cindy Veenhof, Johanna M van Dongen, Joost Dekker and Dinny H de Bakker
    Citation: BMC Musculoskeletal Disorders 2014 15:269
    Content type: Study protocol Published on:

  2. The aim of the present study was to evaluate the accuracy of two approaches using magnetic resonance imaging (MRI) or combined ultrasonography (US) and anti-cyclic citrullinated peptide antibody (ACPA) for dia...

    Authors: Jens K Pedersen, Tove Lorenzen, Bo Ejbjerg, Marcin Szkudlarek, Anne Voss, Mikkel Østergaard, Anders J Svendsen, Lis S Andersen and Kim Hørslev-Petersen
    Citation: BMC Musculoskeletal Disorders 2014 15:268
    Content type: Research article Published on:

  3. There are still many questions related to aseptic femoral stem loosening. Systemic and local immune responses to the implanted “foreign body” is one of the reasons for loosening. The purpose of the study was t...

    Authors: Krzysztof Kmieć, Marek Synder, Piotr Kozłowski, Marek Drobniewski and Marcin Sibiński
    Citation: BMC Musculoskeletal Disorders 2014 15:267
    Content type: Research article Published on:

  4. Patellar tendinopathy is a common cause of activity-related anterior knee pain. Evidence is conflicting as to whether obesity is a risk factor for this condition. The aim of this study was to determine the rel...

    Authors: Jessica Fairley, Jason Toppi, Flavia M Cicuttini, Anita E Wluka, Graham G Giles, Jill Cook, Richard O’Sullivan and Yuanyuan Wang
    Citation: BMC Musculoskeletal Disorders 2014 15:266
    Content type: Research article Published on:

  5. The ‘Parsonage-Turner syndrome’ (PTS) is a rare but distinct disorder with an abrupt onset of shoulder pain, followed by weakness and atrophy of the upper extremity musculature, and a slow recovery requiring m...

    Authors: Duncan P Fransz, Casper P Schönhuth, Tjeerd J Postma and Barend J van Royen
    Citation: BMC Musculoskeletal Disorders 2014 15:265
    Content type: Case report Published on:

  6. Cartilage morphometry based on magnetic resonance images (MRIs) is an emerging outcome measure for clinical trials among patients with knee osteoarthritis (KOA). However, current methods for cartilage morphome...

    Authors: Ming Zhang, Jeffrey B Driban, Lori Lyn Price, Daniel Harper, Grace H Lo, Eric Miller, Robert J Ward and Timothy E McAlindon
    Citation: BMC Musculoskeletal Disorders 2014 15:264
    Content type: Research article Published on:

  7. Recently an RCT confirmed brace efficacy in adolescent idiopathic scoliosis (AIS) patients. Previously, a Cochrane review suggested also producing studies according to the Scoliosis Research Society (SRS) crit...

    Authors: Stefano Negrini, Sabrina Donzelli, Monia Lusini, Salvatore Minnella and Fabio Zaina
    Citation: BMC Musculoskeletal Disorders 2014 15:263
    Content type: Research article Published on:

  8. Due to the advantages of its bone-conserving nature, hip resurface arthroplasty (HRA) has recently gained the interest of orthopedic surgeons for the treatment of young and active patients who have osteonerosi...

    Authors: Ching-Lung Tai, Yung-Chou Chen and Pang-Hsin Hsieh
    Citation: BMC Musculoskeletal Disorders 2014 15:262
    Content type: Research article Published on:

  9. The degree of weightlessness during water immersion is usually estimated through percentage weight bearing (PWB). However, variations in PWB in different standing postures have not been documented. The study w...

    Authors: Babatunde OA Adegoke, Ajediran I Bello and Ademola O Abass
    Citation: BMC Musculoskeletal Disorders 2014 15:261
    Content type: Research article Published on:

  10. Percutaneous vertebroplasy (PVP) might lead to significant radiation exposure to patients, operators, and operating room personnel. Therefore, radiaton exposure is a concern. The aim of this study was to prese...

    Authors: Guang-Quan Zhang, Yan-Zheng Gao, Shu-Lian Chen, Shuai Ding and Kun Gao
    Citation: BMC Musculoskeletal Disorders 2014 15:260
    Content type: Technical advance Published on:

  11. The gait-loading test is a well known, important test with which to assess the involved spinal level in patients with lumbar spinal stenosis. The lumbar extension-loading test also functions as a diagnostic lo...

    Authors: Naoto Takahashi, Shin-ichi Kikuchi, Shoji Yabuki, Koji Otani and Shin-ichi Konno
    Citation: BMC Musculoskeletal Disorders 2014 15:259
    Content type: Research article Published on:

  12. Arthritis pain is reported as one of the most common reasons for persons using medical herbal cannabis in North America. “Severe arthritis” is the condition justifying legal use of cannabis in over half of all...

    Authors: Mary-Ann Fitzcharles, Peter A Ste-Marie, Daniel J Clauw, Shahin Jamal, Jacob Karsh, Sharon LeClercq, Jason J McDougall, Yoram Shir, Kam Shojania and Zach Walsh
    Citation: BMC Musculoskeletal Disorders 2014 15:258
    Content type: Research article Published on:

  13. Vitamin D is essential for calcium metabolism, Vitamin D deficiency can precipitate osteoporosis, cause muscle weakness and increase the risk of fracture. The aim of this study was to assess the prevalence of ...

    Authors: Jawl-Shan Hwang, Keh-Sung Tsai, Yuh-Min Cheng, Wen-Jer Chen, Shih-Te Tu, Ko-Hsiu Lu, Sheng-Mou Hou, Shu-Hua Yang, Henrich Cheng, Hung Jen Lai, Sharon Lei and Jung-Fu Chen
    Citation: BMC Musculoskeletal Disorders 2014 15:257
    Content type: Research article Published on:

  14. KIR genes coding for natural killer cell immunoglobulin-like receptors, KIR, influence the effector and regulatory function of NK cells as well as some subpopulations of T lymphocytes (e.g. CD4+CD28-KIR+) depend...

    Authors: Edyta Majorczyk, Andrzej Pawlik, Daria Gendosz and Piotr Kuśnierczyk
    Citation: BMC Musculoskeletal Disorders 2014 15:256
    Content type: Research article Published on:

  15. Low back pain (LBP) is the leading cause of disability worldwide. Evidence pointing towards a more efficacious model of care using a biopsychosocial approach for LBP management highlights the need to understan...

    Authors: B-K Tan, Anne J Smith, Peter B O’Sullivan, Gang Chen, Angus F Burnett and Andrew M Briggs
    Citation: BMC Musculoskeletal Disorders 2014 15:255
    Content type: Research article Published on:

  16. Exercise is consistently recommended for older adults with knee pain related to osteoarthritis. However, the effects from exercise are typically small and short-term, likely linked to insufficient individualis...

    Authors: Nadine E Foster, Emma L Healey, Melanie A Holden, Elaine Nicholls, David GT Whitehurst, Susan Jowett, Clare Jinks, Edward Roddy and Elaine M Hay
    Citation: BMC Musculoskeletal Disorders 2014 15:254
    Content type: Study protocol Published on:

  17. Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mediated by T cells. The aim of the present study was to investigate the therapeutic efficacy of synthetic peptides (HP-R1, HP-R2 and HP-R3)...

    Authors: Xiao-Lian Shi, Li-Ping Wang, Xuan Feng, Dan-Dan Fan, Wei-Jin Zang, Bing Wang and Jun Zhou
    Citation: BMC Musculoskeletal Disorders 2014 15:253
    Content type: Research article Published on:

  18. Although arthroscopy of upper extremity joints was initially a diagnostic tool, it is increasingly used for therapeutic interventions. Randomized controlled trials (RCTs) are considered the gold standard for a...

    Authors: Kamelia Tadjerbashi, Roberto S Rosales and Isam Atroshi
    Citation: BMC Musculoskeletal Disorders 2014 15:252
    Content type: Research article Published on:

  19. Rheumatoid arthritis (RA) is a chronic autoinflammatory joint disease which leads to the destruction of joints and disability of the patients. Anti-tumour necrosis factor (anti-TNF) drugs can halt radiological...

    Authors: Péter Juhász, Ádám Mester, Anna-Julianna Biró, Gábor Héjj and Gyula Poór
    Citation: BMC Musculoskeletal Disorders 2014 15:251
    Content type: Research article Published on:

  20. This study aimed to present functional results and patient’s health related quality of life (HRQOL) data ten years after volar locked plate fixation (VPF) of unstable intra-articular distal radial fractures (D...

    Authors: Paul Ruckenstuhl, Gerwin A Bernhardt, Patrick Sadoghi, Mathias Glehr, Lukas A Holzer, Andreas Leithner, Matthias Wolf and Gerald Gruber
    Citation: BMC Musculoskeletal Disorders 2014 15:250
    Content type: Research article Published on:

  21. The objective was to identify severity characteristics of initial chikungunya infection (CHIKV) stages associated with post-CHIKV arthritis and arthralgia.

    Authors: Hafiz Muhammad Yaseen, Fabrice Simon, Xavier Deparis and Catherine Marimoutou
    Citation: BMC Musculoskeletal Disorders 2014 15:249
    Content type: Research article Published on:

  22. Patient expectations regarding surgery may be related to outcomes in total joint replacement (TJR). The aim of this study was to determine the association of patient expectations with health related quality of...

    Authors: Marta Gonzalez Saenz de Tejada, Antonio Escobar, Amaia Bilbao, Carmen Herrera-Espiñeira, Lidia García-Perez, Felipe Aizpuru and Cristina Sarasqueta
    Citation: BMC Musculoskeletal Disorders 2014 15:248
    Content type: Research article Published on:

  23. To evaluate the clinical significance of lateral lumbar spinal canal stenosis (LLSCS), found by magnetic resonance imaging (MRI), through correlating the imaging findings with patient symptoms, walking capacit...

    Authors: Pekka Kuittinen, Petri Sipola, Timo Juhani Aalto, Sara Määttä, Anita Parviainen, Tapani Saari, Sanna Sinikallio, Sakari Savolainen, Veli Turunen, Heikki Kröger, Olavi Airaksinen and Ville Leinonen
    Citation: BMC Musculoskeletal Disorders 2014 15:247
    Content type: Research article Published on:

  24. Musculus gastrocnemius tightness (MGT) can be diagnosed by comparing ankle dorsiflexion (ADF) with the knee extended and flexed. Although various measurement techniques exist, the degree of knee flexion needed...

    Authors: Sebastian F Baumbach, Mareen Brumann, Jakob Binder, Wolf Mutschler, Markus Regauer and Hans Polzer
    Citation: BMC Musculoskeletal Disorders 2014 15:246
    Content type: Research article Published on:

  25. Biomechanical testing is an essential component of bone research. In order to test the metaphyseal region of long bones, a typical location for the nowadays increasing field of osteoporotic bone changes, three...

    Authors: Gina Alicia Mackert, Christoph Hirche, Helmut Harhaus, Dimitra Kotsougiani, Bernd Hoener, Ulrich Kneser and Leila Harhaus
    Citation: BMC Musculoskeletal Disorders 2014 15:245
    Content type: Research article Published on:

  26. Total shoulder arthroplasty (TSA) can improve function in osteoarthritic shoulders, but the ability to perform activities of daily living (ADLs) can still remain impaired. Routinely, shoulder surgeons measure ...

    Authors: Michael W Maier, Mirjam Niklasch, Thomas Dreher, Felix Zeifang, Oliver Rettig, Matthias C Klotz, Sebastian I Wolf and Philip Kasten
    Citation: BMC Musculoskeletal Disorders 2014 15:244
    Content type: Research article Published on:

  27. Generalized Joint Hypermobility (GJH) has been found to be associated with musculoskeletal complaints and disability. For others GJH is seen as a prerequisite in order to excel in certain sports like dance. Ho...

    Authors: Mark C Scheper, Janneke E de Vries, Birgit Juul-Kristensen, Frans Nollet and Raoul hh Engelbert
    Citation: BMC Musculoskeletal Disorders 2014 15:243
    Content type: Research article Published on:

  28. Peripheral quantitative computed tomography (pQCT) is an established technology that allows for the measurement of the material properties of bone. Alterations to bone architecture are associated with an incre...

    Authors: Elodie Chaplais, David Greene, Anita Hood, Scott Telfer, Verona du Toit, Davinder Singh-Grewal, Joshua Burns, Keith Rome, Daniel J Schiferl and Gordon J Hendry
    Citation: BMC Musculoskeletal Disorders 2014 15:242
    Content type: Technical advance Published on:

  29. Tennis is believed to be potentially harmful for the shoulder, therefore the purpose of this study is to evaluate the anatomy of the rotator cuff and the coraco-humeral ligament (CHL) in a-symptomatic non-elit...

    Authors: Alberto Tagliafico, Angela Cadoni, Bianca Bignotti and Carlo Martinoli
    Citation: BMC Musculoskeletal Disorders 2014 15:241
    Content type: Research article Published on:

  30. The objectives of this study were to describe changes in physical activity profiles of Korean patients after TKA and to determine whether the postoperative physical activity level is influenced by patient soci...

    Authors: Moon Jong Chang, Sung Hee Kim, Yeon Gwi Kang, Chong Bum Chang and Tae Kyun Kim
    Citation: BMC Musculoskeletal Disorders 2014 15:240
    Content type: Research article Published on:

  31. Glucocorticoid has been used extensively in clinical applications, because of its several pharmacologic actions, which include immunosuppression, anti-inflammation, anti-shock, and relief of asthma. However, t...

    Authors: Da-An Zhou, Hong-Xin Zheng, Cheng-Wen Wang, Dan Shi and Jian-Jun Li
    Citation: BMC Musculoskeletal Disorders 2014 15:239
    Content type: Research article Published on:

  32. Estradiol plays an important role in the regulation of collagen metabolism. Deficiency of estradiol has been reported to be associated with the degeneration of many connective tissues. However, the association...

    Authors: Mei-Hsiu Chen, Chao-Kai Hu, Pei-Ru Chen, Yu-Shan Chen, Jui-Sheng Sun and Ming-Hong Chen
    Citation: BMC Musculoskeletal Disorders 2014 15:238
    Content type: Research article Published on:

  33. 187,000 hip and knee joint replacements are performed every year in the National Health Service (NHS). One of the commonest complications is surgical site infection (SSI), and this represents a significant bur...

    Authors: Andrew P Sprowson, Cyrus D Jensen, Nick Parsons, Paul Partington, Kevin Emmerson, Ian Carluke, Seif Asaad, Roland Pratt, Scott Muller and Mike R Reed
    Citation: BMC Musculoskeletal Disorders 2014 15:237
    Content type: Study protocol Published on:

  34. It is known that individuals with bilateral spastic cerebral palsy (BSCP) have small and weak muscles. However, no studies to date have investigated intramuscular fat infiltration in this group. The objective ...

    Authors: Jonathan J Noble, Geoffrey D Charles-Edwards, Stephen F Keevil, Andrew P Lewis, Martin Gough and Adam P Shortland
    Citation: BMC Musculoskeletal Disorders 2014 15:236
    Content type: Research article Published on:

  35. Thoughtful use of assessment tools to monitor disease requires an understanding of clinimetric properties. These properties are often under-reported and, thus, potentially overlooked in the clinic. This study ...

    Authors: Justine M Naylor, Andrew Hayen, Edward Davidson, Danella Hackett, Ian A Harris, Gihan Kamalasena and Rajat Mittal
    Citation: BMC Musculoskeletal Disorders 2014 15:235
    Content type: Research article Published on:

  36. It has not been shown whether accelerated rehabilitation following periacetabular osteotomy (PAO) is effective for early recovery. The purpose of this retrospective study was to compare complication rates in p...

    Authors: Hiroshi Ito, Hiromasa Tanino, Tatsuya Sato, Yasuhiro Nishida and Takeo Matsuno
    Citation: BMC Musculoskeletal Disorders 2014 15:234
    Content type: Research article Published on:

  37. Anterior cervical discectomy and fusion (ACDF) was one of the preferred treatments for degenerative cervical spondylosis. However, the motion of adjacent segment was significantly increased after operation. So...

    Authors: RuoFu Zhu, HuiLin Yang, ZhiDong Wang, GenLin Wang, MinJie Shen and Quan Yuan
    Citation: BMC Musculoskeletal Disorders 2014 15:233
    Content type: Research article Published on:

  38. Musculoskeletal pain is a major contributor to short and long term work absence. Patients seek care from their general practitioner (GP) and yet GPs often feel ill-equipped to deal with work issues. Providing ...

    Authors: Annette Bishop, Gwenllian Wynne-Jones, Sarah A Lawton, Danielle van der Windt, Chris Main, Gail Sowden, A Kim Burton, Martyn Lewis, Sue Jowett, Tom Sanders, Elaine M Hay and Nadine E Foster
    Citation: BMC Musculoskeletal Disorders 2014 15:232
    Content type: Study protocol Published on:

  39. Physical activity (PA) plays an important role in the prevention and management of a number of chronic conditions. Aim: to investigate the evidence for effectiveness of pedometer-driven walking programs to pro...

    Authors: Suliman Mansi, Stephan Milosavljevic, G David Baxter, Steve Tumilty and Paul Hendrick
    Citation: BMC Musculoskeletal Disorders 2014 15:231
    Content type: Research article Published on:

  40. Medial open wedge high tibial osteotomy is a well-established procedure for the treatment of unicompartmental osteoarthritis and symptomatic varus malalignment. We hypothesized that different fixation devices ...

    Authors: Мaxim L Golovakhа, Weniamin Orljanski, Karl-Peter Benedetto, Sergey Panchenko, Philippe Büchler, Philipp Henle and Emin Aghayev
    Citation: BMC Musculoskeletal Disorders 2014 15:230
    Content type: Research article Published on:

  41. Clinicians commonly examine posture and movement in people with the belief that correcting dysfunctional movement may reduce pain. If dysfunctional movement is to be accurately identified, clinicians should kn...

    Authors: Robert A Laird, Jayce Gilbert, Peter Kent and Jennifer L Keating
    Citation: BMC Musculoskeletal Disorders 2014 15:229
    Content type: Research article Published on:

  42. Rotator cuff tears are a common cause of shoulder pain. There is an absence of information about symptomatic rotator cuffs from the patients’ perspective; this limits the information clinicians can share with ...

    Authors: Catherine J Minns Lowe, Jane Moser and Karen Barker
    Citation: BMC Musculoskeletal Disorders 2014 15:228
    Content type: Research article Published on:

  43. Studies on hypothalamic-pituitary-adrenal axis (HPA-axis) function amongst patients with chronic pain show equivocal results and well-controlled cohort studies are rare in this field. The goal of our study was...

    Authors: Ellen Generaal, Nicole Vogelzangs, Gary J Macfarlane, Rinie Geenen, Johannes H Smit, Brenda WJH Penninx and Joost Dekker
    Citation: BMC Musculoskeletal Disorders 2014 15:227
    Content type: Research article Published on:

  44. Impaired stability is a risk factor in knee osteoarthritis (OA), where the whole joint and not only the joint cartilage is affected. The meniscus provides joint stability and is involved in the early pathologi...

    Authors: Ulf Sigurdsson, Carl Siversson, Eveliina Lammentausta, Jonas Svensson, Carl-Johan Tiderius and Leif E Dahlberg
    Citation: BMC Musculoskeletal Disorders 2014 15:226
    Content type: Research article Published on:

  45. Alagille syndrome is a multisystem disorder, which is characterized by hypoplasia of the intrahepatic bile ducts, malformations of the cardiovascular system, eyes, and vertebral column, and abnormal facies. Se...

    Authors: Koji Nozaka, Yoichi Shimada, Naohisa Miyakoshi, Shin Yamada, Yuji Kasukawa and Atsuko Noguchi
    Citation: BMC Musculoskeletal Disorders 2014 15:225
    Content type: Case report Published on:

  46. Muscle atrophy caused by immobilization in the shortened position is characterized by a decrease in the size or cross-sectional area (CSA) of myofibers and decreased muscle length. Few studies have addressed t...

    Authors: Momoko Nagai, Tomoki Aoyama, Akira Ito, Hirotaka Iijima, Shoki Yamaguchi, Junichi Tajino, Xiangkai Zhang, Haruhiko Akiyama and Hiroshi Kuroki
    Citation: BMC Musculoskeletal Disorders 2014 15:224
    Content type: Research article Published on:

  48. A double-network (DN) gel, which was composed of poly-(2-Acrylamido-2-methylpropanesulfonic acid) and poly-(N,N’-dimethyl acrylamide) (PAMPS/PDMAAm), has the potential to induce chondrogenesis both in vitro an...

    Authors: Nobuto Kitamura, Takayuki Kurokawa, Takaaki Fukui, Jian P Gong and Kazunori Yasuda
    Citation: BMC Musculoskeletal Disorders 2014 15:222
    Content type: Research article Published on:

  49. Interspinous spacers are a minimally invasive surgical alternative for patients with lumbar spinal stenosis (LSS) unresponsive to conservative care. The purpose of this prospective, multicenter, randomized, co...

    Authors: Vikas V Patel, Peter G Whang, Thomas R Haley, W Daniel Bradley, Pierce D Nunley, Larry E Miller, Jon E Block and Fred H Geisler
    Citation: BMC Musculoskeletal Disorders 2014 15:221
    Content type: Research article Published on:

  50. Surgical pain is managed with multi-modal anaesthesia in total hip replacement (THR) and total knee replacement (TKR). It is unclear whether including local anaesthetic infiltration before wound closure provid...

    Authors: Elsa MR Marques, Hayley E Jones, Karen T Elvers, Mark Pyke, Ashley W Blom and Andrew D Beswick
    Citation: BMC Musculoskeletal Disorders 2014 15:220
    Content type: Research article Published on:
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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