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  1. To investigate the risk of hepatitis B virus (HBV) reactivation in rheumatoid arthritis (RA) patients with HBV carrier state during treatment of disease-modifying antirheumatic drugs (DMARDs) and the use of an...

    Authors: Ying-Qian Mo, An-Qi Liang, Jian-Da Ma, Le-Feng Chen, Dong-Hui Zheng, H Ralph Schumacher and Lie Dai
    Citation: BMC Musculoskeletal Disorders 2014 15:449
  2. Longitudinal assessment of bone marrow lesions (BMLs) in knee osteoarthritis (KOA) by MRI is usually performed using semi-quantitative grading methods. Quantitative segmentation methods may be more sensitive t...

    Authors: Flemming K Nielsen, Niels Egund, David Peters and Anne Grethe Jurik
    Citation: BMC Musculoskeletal Disorders 2014 15:447
  3. The objective of this study was to identify leukocyte cell types found within the synovia of patients with seronegative spondylarthropathies (SpA), such as ankylosing spondylitis (AS), using transcription base...

    Authors: Robin M Hallett and Tracy Chew
    Citation: BMC Musculoskeletal Disorders 2014 15:446
  4. People with rheumatoid arthritis are at greater risk of morbidity and mortality from cardiovascular disease than the general population. Sustained physical activity increases cardio-respiratory fitness and red...

    Authors: Peter C Rouse, Jet JCS Veldhuijzen Van Zanten, George S Metsios, Nikos Ntoumanis, Chen-an Yu, Yiannis Koutedakis, Sally AM Fenton, Joanna Coast, Hema Mistry, George D Kitas and Joan L Duda
    Citation: BMC Musculoskeletal Disorders 2014 15:445
  5. Among laboratory technicians, the prevalence of neck and shoulder pain is widespread possibly due to typical daily work tasks such as pipetting, preparing vial samples for analysis, and data processing on a co...

    Authors: Kenneth Jay, Mikkel Brandt, Emil Sundstrup, MC schraefel, Markus D Jakobsen, Gisela Sjøgaard and Lars L Andersen
    Citation: BMC Musculoskeletal Disorders 2014 15:444
  6. Percutaneous pedicle screw instrumentation is a minimally invasive surgical technique; however, the effects of using percutaneous pedicle screw fixation in treating patients with spinal infections have not yet...

    Authors: Tung-Yi Lin, Tsung-Ting Tsai, Meng-Ling Lu, Chi-Chien Niu, Ming-Kai Hsieh, Tsai-Sheng Fu, Po-Liang Lai, Lih-Huei Chen and Wen-Jer Chen
    Citation: BMC Musculoskeletal Disorders 2014 15:443
  7. Obesity is a well-known risk factor for osteoarthritis (OA). The majority of obesity research in OA is performed using self-reported BMI-data, however, its validity in persons with OA is unknown. The aim of th...

    Authors: Karin Magnusson, Ida K Haugen, Nina Østerås, Lars Nordsletten, Bård Natvig and Kåre Birger Hagen
    Citation: BMC Musculoskeletal Disorders 2014 15:442
  8. Few, if any data are available are available regarding the time-trends in characteristics of patients who have undergone primary THA. Our objective was to examine the time-trends in key demographic and clinica...

    Authors: Jasvinder A Singh and David G Lewallen
    Citation: BMC Musculoskeletal Disorders 2014 15:441
  9. Shoulder instability is a common problem affecting young adults. Stabilization surgery followed by physiotherapy rehabilitation has been shown to reduce the chance of further episodes of shoulder dislocation a...

    Authors: Anju Jaggi, Susan Alexander, Robert Herbert, Lennard Funk and Karen A Ginn
    Citation: BMC Musculoskeletal Disorders 2014 15:439
  10. The aim of our meta-analysis is to understand the relationship between the pathogenesis of osteoarthritis and the expression levels of vascular endothelial growth factor (VEGF) in multiple disease tissues in o...

    Authors: Quan Yuan, Li Sun, Jian-Jun Li and Chun-Hou An
    Citation: BMC Musculoskeletal Disorders 2014 15:437
  11. Lateral ankle sprain (LAS) has often been considered an injury leading to localized joint impairments affecting the musculoskeletal system. Persistent chronic ankle instability and bilateral alterations in mot...

    Authors: Maude Bastien, Hélène Moffet, Laurent J Bouyer, Marc Perron, Luc J Hébert and Jean Leblond
    Citation: BMC Musculoskeletal Disorders 2014 15:436
  12. The main goals of the standard treatment for advanced symptomatic knee osteoarthritis, total knee arthroplasty (TKA), are pain reduction and restoration of knee motion.

    Authors: Matthias Christen, Emin Aghayev and Bernhard Christen
    Citation: BMC Musculoskeletal Disorders 2014 15:435
  13. Although minimally invasive approaches are widely used in many areas of orthopedic surgery nonunion therapy remains a domain of open surgery. Some attempts have been made to introduce minimally invasive proced...

    Authors: Thorsten Tjardes, Michael Roland, Robin Otchwemah, Tim Dahmen, Stefan Diebels and Bertil Bouillon
    Citation: BMC Musculoskeletal Disorders 2014 15:434
  14. The prosthesis of contemporary total knee arthroplasty (TKA) has been modified to provide a more familiar environment for higher flexion angle of the replaced knee. The design modifications continue based on e...

    Authors: Jai Gon Seo, Young-Wan Moon, Moon Jong Chang, Byung Chul Jo, Yong Beom Park, Deuk Soo Lim and Byung Hoon Lee
    Citation: BMC Musculoskeletal Disorders 2014 15:433
  15. The Swedish National Patient Register offers unique possibilities for identification of large cohorts, such as patients with rheumatoid arthritis (RA). Although the overall diagnostic validity in the register ...

    Authors: Kristin Waldenlind, Jonas K Eriksson, Bernhard Grewin and Johan Askling
    Citation: BMC Musculoskeletal Disorders 2014 15:432
  16. Cartilage is an avascular and aneural tissue. Chondrocytes thrive in this restricted environment of low oxygen tension and poor nutrient availability which has led to suggestions that hypoxia may be a protecti...

    Authors: Karl Alvarez, María C de Andrés, Atsushi Takahashi and Richard O C Oreffo
    Citation: BMC Musculoskeletal Disorders 2014 15:431
  17. Patients with anterior cruciate ligament (ACL) injury often exhibit reduced movement quality during functional tasks in the form of a knee-medial-to-foot position (KMFP). This movement pattern is suggested to ...

    Authors: Anna Cronström and Eva Ageberg
    Citation: BMC Musculoskeletal Disorders 2014 15:430
  18. Abnormal longitudinal growth has been identified in the early pubertal stage of idiopathic scoliosis (IS) and is thought to contribute to the development of scoliosis. This phenotype may be caused by abnormal ...

    Authors: Xin Zheng, Weijun Wang, Bangping Qian, Shoufeng Wang, Zezhang Zhu, Bin Wang, Xu Sun, Yitao Ding and Yong Qiu
    Citation: BMC Musculoskeletal Disorders 2014 15:429
  19. Joint hypermobility is a common clinical characteristic of patients with Osteogenesis imperfecta (OI), a disorder with serious comorbidities of scoliosis and cranial base anomalies. This study aimed at evaluat...

    Authors: Heidi Arponen, Outi Mäkitie and Janna Waltimo-Sirén
    Citation: BMC Musculoskeletal Disorders 2014 15:428
  20. Written information can be of benefit to both practitioners and patients and the provision of quality information is emphasised as a core intervention by United Kingdom National Institute of Clinical Excellence (...

    Authors: Andrew Morden, Clare Jinks, Bie Nio Ong, Mark Porcheret and Krysia S Dziedzic
    Citation: BMC Musculoskeletal Disorders 2014 15:427
  21. Chondromalacia, lateral patellar compression syndrome and osteoarthritis are common patellofemoral joint disorders leading to functional and/or structural disturbances in articular surfaces. The objective of t...

    Authors: Dawid Bączkowicz and Edyta Majorczyk
    Citation: BMC Musculoskeletal Disorders 2014 15:426
  22. Recent work has shown that the gap junction protein connexin43 (Cx43) is upregulated in cells of the joint during osteoarthritis (OA). Here we examined if the OA-associated increase in Cx43 expression impacts ...

    Authors: Aditi Gupta, Corinne Niger, Atum M Buo, Eric R Eidelman, Richard J Chen and Joseph P Stains
    Citation: BMC Musculoskeletal Disorders 2014 15:425
  23. Expandable screws have greater pullout strength than conventional screws. The purpose of this study was to compare the biomechanical stability provided by a new built-in expandable anterior spinal fixation sys...

    Authors: Chu-Song Zhou, Yan-Fang Xu, Yu Zhang, Zhong Chen and Hai Lv
    Citation: BMC Musculoskeletal Disorders 2014 15:424
  24. Subjective symptoms of temporomandibular disorders (TMDs) have rarely been studied by age group. We aimed to compare self-reported pain intensity, sleeping difficulty, and treatment outcomes of patients with m...

    Authors: Hiroyuki Karibe, Greg Goddard, Kisaki Shimazu, Yuichi Kato, Sachie Warita-Naoi and Tomomi Kawakami
    Citation: BMC Musculoskeletal Disorders 2014 15:423
  25. Notochordal cells (NC) remain in the focus of research for regenerative therapy for the degenerated intervertebral disc (IVD) due to their progenitor status. Recent findings suggested their regenerative action...

    Authors: Benjamin Gantenbein, Elena Calandriello, Karin Wuertz-Kozak, Lorin M Benneker, Marius JB Keel and Samantha CW Chan
    Citation: BMC Musculoskeletal Disorders 2014 15:422
  26. Sternoclavicular joint (SCJ) arthropathy is an uncommon cause of mechanical pain. The aim of this study is to evaluate the diagnostic value of two active clinical tests for localizing the sternoclavicular join...

    Authors: Alexander Van Tongel, Anne Karelse, Bart Berghs, Tom Van Isacker and Lieven De Wilde
    Citation: BMC Musculoskeletal Disorders 2014 15:421
  27. Chronic low back pain is one of the four most common diseases in the world with great socioeconomic impact. Supervised exercise therapy is one of the treatments suggested for this condition; however, the recom...

    Authors: Yuri Rafael dos Santos Franco, Richard Eloin Liebano, Katherinne Ferro Moura, Naiane Teixeira Bastos de Oliveira, Gisela Cristiane Miyamoto, Matheus Oliveira Santos and Cristina Maria Nunes Cabral
    Citation: BMC Musculoskeletal Disorders 2014 15:420
  28. Neck pain is a common musculoskeletal complaint and is often associated with shoulder or arm pain. There is a paucity of information on effective treatment for neck and arm pain, such as radiculopathy or cervi...

    Authors: Cato A Basson, Aimee Stewart and Witness Mudzi
    Citation: BMC Musculoskeletal Disorders 2014 15:419
  29. Primary care pharmacological management of new musculoskeletal conditions is not consistent, despite guidelines which recommend prescribing basic analgesics before higher potency medications such as opioids or...

    Authors: Mehluli Ndlovu, John Bedson, Peter W Jones and Kelvin P Jordan
    Citation: BMC Musculoskeletal Disorders 2014 15:418
  30. Use of a baseplate with a smaller diameter in reverse shoulder arthroplasty is increasing, especially in patients with a small glenoid or glenoid wear. However, the effect of a smaller baseplate on stability o...

    Authors: Soo-Won Chae, Soung-Yon Kim, Haea Lee, Joung-Ro Yon, Juneyoung Lee and Seung-Ho Han
    Citation: BMC Musculoskeletal Disorders 2014 15:417
  31. Non-specific low back pain (NSLBP) is a large and costly problem. It has a lifetime prevalence of 80% and results in high levels of healthcare cost. It is a major cause for long term sickness amongst the workf...

    Authors: Benjamin E Smith, Chris Littlewood and Stephen May
    Citation: BMC Musculoskeletal Disorders 2014 15:416
  32. The harvest of iliac crest bone grafts (ICBG) is associated with relevant donor site pain, but may be lowered by the application of lidocaine loaded on biodegradable, hemostatic putty for sustained local analg...

    Authors: Marc Andreas Müller, Arne Mehrkens, Roman Zürcher, Patrick Vavken and Victor Valderrabano
    Citation: BMC Musculoskeletal Disorders 2014 15:415
  33. PA28γ (also known as Ki, REG gamma, PMSE3), a member of the ubiquitin-and ATP-independent proteasome activator family 11S, has been proved to show proteasome-dependent and -independent effects on several prote...

    Authors: Melanie Gruner, Anja Moncsek, Stefan Rödiger, Dagmar Kühnhardt, Eugen Feist and Ralf Stohwasser
    Citation: BMC Musculoskeletal Disorders 2014 15:414
  34. The Patient and PRovider Interventions for Managing Osteoarthritis (OA) in Primary Care (PRIMO) study is one of the first health services trials targeting OA in a multi-site, primary care network. This multi-s...

    Authors: Kelli D Allen, Hayden B Bosworth, Ranee Chatterjee, Cynthia J Coffman, Leonor Corsino, Amy S Jeffreys, Eugene Z Oddone, Catherine Stanwyck, William S Yancy Jr and Rowena J Dolor
    Citation: BMC Musculoskeletal Disorders 2014 15:413
  35. Musculoskeletal pain from the upper extremity and shoulder region is commonly reported by computer users. However, the functional status of central pain mechanisms, i.e., central sensitization and conditioned ...

    Authors: Hong-You Ge, Steffen Vangsgaard, Øyvind Omland, Pascal Madeleine and Lars Arendt-Nielsen
    Citation: BMC Musculoskeletal Disorders 2014 15:412
  36. The persistence of knee pain (KP) and its relationship with occupational factors were investigated in two prospective cohorts of French workers: retirees of the Gazel cohort and workers in the Cosali cohort.

    Authors: Eléonore Herquelot, Julie Bodin, Audrey Petit, Catherine Ha, Annette Leclerc, Marcel Goldberg, Marie Zins, Yves Roquelaure and Alexis Descatha
    Citation: BMC Musculoskeletal Disorders 2014 15:411
  37. The impact of anti-TNF, corticosteroid and analgesic therapy on inflammation and pain was evaluated in a novel mono-arthritic multi-flare rat Streptococcal Cell Wall (SCW) model using Etanercept, Dexamethasone...

    Authors: Kalyan Chakravarthy, Robert Faltus, Gain Robinson, Raquel Sevilla, John Shin, Mark Zielstorff, Alan Byford, Erica Leccese, Michael J Caniga, SuChun Hseih, Shuli Zhang, Chi-Sung Chiu, Jie Zhang-Hoover, Lily Y Moy, Robbie L McLeod, Dana Stoffregen…
    Citation: BMC Musculoskeletal Disorders 2014 15:409
  38. The reliability of clinical tests for the cervical spine has not been adequately evaluated. Six cervical clinical tests, which are low cost and easy to perform in clinical settings, were tested for intra- and ...

    Authors: René Jørgensen, Inge Ris, Deborah Falla and Birgit Juul-Kristensen
    Citation: BMC Musculoskeletal Disorders 2014 15:408
  39. Risk factors have been proposed for running injuries including (a) reduced muscular strength, (b) excessive joint movements and (c) excessive joint moments in the frontal and transverse planes. To date, many r...

    Authors: Jennifer Baltich, Carolyn A Emery, Darren Stefanyshyn and Benno M Nigg
    Citation: BMC Musculoskeletal Disorders 2014 15:407
  40. “Chevron”-Olecranon osteotomies are commonly used for the approach to intraarticular distal humerus fractures but are often associated with procedure related complications. We studied the triceps reflecting ap...

    Authors: Lukas Daniel Iselin, Tobias Mett, Reto Babst, Marcel Jakob and Daniel Rikli
    Citation: BMC Musculoskeletal Disorders 2014 15:406
  41. Knee osteoarthritis (OA) progression has been linked to increased peak external knee adduction moments (KAMs). Although some trials have attempted to reduce pain and improve function in OA by reducing KAMs wit...

    Authors: Ryan T Lewinson, Kelsey H Collins, Isabelle A Vallerand, J Preston Wiley, Linda J Woodhouse, Raylene A Reimer, Jay T Worobets, Walter Herzog and Darren J Stefanyshyn
    Citation: BMC Musculoskeletal Disorders 2014 15:405
  42. Previous studies investigating the association between GDF5 rs143383 polymorphism and knee osteoarthritis (OA) have suggested stronger associations in Asians than Caucasians, but limitations on the amount of a...

    Authors: Feng Pan, Jing Tian, Tania Winzenberg, Changhai Ding and Graeme Jones
    Citation: BMC Musculoskeletal Disorders 2014 15:404
  43. Rheumatoid arthritis (RA) is a chronic autoimmune condition that results in pain and disability. Patients with RA have a decreased functional ability and are forced into a sedentary lifestyle and as such, thes...

    Authors: Alessandra Prioreschi, Mohammed Tikly and Joanne A McVeigh
    Citation: BMC Musculoskeletal Disorders 2014 15:403
  44. Movement control impairment reduces active control of movement. Patients with this might form an important subgroup among patients with mechanical cervical pain. Diagnosis is based on the observation of active...

    Authors: Maja Patroncini, Susanne Hannig, André Meichtry and Hannu Luomajoki
    Citation: BMC Musculoskeletal Disorders 2014 15:402
  45. The one-stage procedure for treatment of older developmental dislocation of the hip (DDH) is used widely. However, the best age group for this operation is still unknown. The aims of our study were to evaluate...

    Authors: Bo Ning, Yi Yuan, Jie Yao, Sichng Zhang and Jun Sun
    Citation: BMC Musculoskeletal Disorders 2014 15:401
  46. Osteoporosis, a disease characterized by low bone mineral density (BMD), is an important health problem in Mexico. BMD is a highly heritable trait, with heritability estimates of 50-85%. Several candidate gene...

    Authors: Rafael Velázquez-Cruz, Rogelio F Jiménez-Ortega, Alma Y Parra-Torres, Manuel Castillejos-López, Nelly Patiño, Manuel Quiterio, Teresa Villarreal-Molina and Jorge Salmerón
    Citation: BMC Musculoskeletal Disorders 2014 15:400
  47. Conclusive evidence indicating an effective treatment for carpal tunnel syndrome (CTS), a common entrapment neuropathy, is lacking. Ultrasound therapy (US therapy) has long been used as one of the combination ...

    Authors: Yi-Wei Chang, Shih-Fu Hsieh, Yu-Shiow Horng, Hui-Ling Chen, Kun-Chang Lee and Yi-Shiung Horng
    Citation: BMC Musculoskeletal Disorders 2014 15:399

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