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  1. Leg pain associated with low back pain (LBP) is recognized as a risk factor for a poor prognosis, and is included as a component in most LBP classification systems. The location of leg pain relative to the kne...

    Authors: Alice Kongsted, Peter Kent, Hanne Albert, Tue Secher Jensen and Claus Manniche
    Citation: BMC Musculoskeletal Disorders 2012 13:236
  2. One major drawback in measuring ground-reaction forces during running is that it is time consuming to get representative ground-reaction force (GRF) values with a traditional force platform. An instrumented fo...

    Authors: Bas Kluitenberg, Steef W Bredeweg, Sjouke Zijlstra, Wiebren Zijlstra and Ida Buist
    Citation: BMC Musculoskeletal Disorders 2012 13:235
  3. Common low back pain represents a major public health problem in terms of its direct cost to health care and its socio-economic repercussions. Ten percent of individuals who suffer from low back pain evolve to...

    Authors: Angélique Denis, Amélie Zelmar, Marie-Annick Le Pogam, Emmanuelle Chaleat-Valayer, Alain Bergeret and Cyrille Colin
    Citation: BMC Musculoskeletal Disorders 2012 13:234
  4. Meniscectomy is a risk factor for knee osteoarthritis, with increased medial joint loading a likely contributor to the development and progression of knee osteoarthritis in this group. Therefore, post-surgical...

    Authors: Michelle Hall, Rana S Hinman, Tim V Wrigley, Ewa M Roos, Paul W Hodges, Margaret Staples and Kim L Bennell
    Citation: BMC Musculoskeletal Disorders 2012 13:233
  5. Breast cancer is the most common malignancy and the second leading cause of death in women. Because bone metastases are a common finding in patients with breast cancer, they are of major clinical concern.

    Authors: Bernd Wegener, Marcus Schlemmer, Joachim Stemmler, Volkmar Jansson, Hans Roland Dürr and Matthias F Pietschmann
    Citation: BMC Musculoskeletal Disorders 2012 13:232
  6. The posterior cruciate ligament (PCL) plays an important role in maintaining physiological kinematics and function of the knee joint. To date mainly in-vitro models or combined magnetic resonance and fluorosco...

    Authors: Ruediger von Eisenhart-Rothe, Ulrich Lenze, Stefan Hinterwimmer, Florian Pohlig, Heiko Graichen, Thomas Stein, Frederic Welsch and Rainer Burgkart
    Citation: BMC Musculoskeletal Disorders 2012 13:231
  7. Rheumatoid Arthritis (RA) commonly affects the hands and wrists with inflammation, deformity, pain, weakness and restricted mobility leading to reduced function. The effectiveness of exercise for RA hands is u...

    Authors: Jo Adams, Chris Bridle, Sukhdeep Dosanjh, Peter Heine, Sarah E Lamb, Joanne Lord, Christopher McConkey, Vivien Nichols, Francine Toye, Martin R Underwood, Mark A Williams and Esther M Williamson
    Citation: BMC Musculoskeletal Disorders 2012 13:230
  8. Platelet Rich Plasma (PRP), a blood-derived product rich in growth factors, is a promising treatment for cartilage defects but there is still a lack of clinical evidence. The aim of this study is to show, thro...

    Authors: Giuseppe Filardo, Elizaveta Kon, Alessandro Di Martino, Berardo Di Matteo, Maria Letizia Merli, Annarita Cenacchi, Pier Maria Fornasari and Maurilio Marcacci
    Citation: BMC Musculoskeletal Disorders 2012 13:229
  9. To investigate whether or not coadministration of tacrolimus (TAC) with prednisolone (PSL) can produce a beneficial effect in the treatment of polymyositis/ dermatomyositis (PM/DM).

    Authors: Yasuhiro Shimojima, Wataru Ishii, Masayuki Matsuda, Ko-ichi Tazawa and Shu-ichi Ikeda
    Citation: BMC Musculoskeletal Disorders 2012 13:228
  10. We systematically reviewed etiological factors of Kienböck’s disease (osteonecrosis of the lunate) discussed in the literature in order to examine the justification for including Kienböck’s disease (KD) in the...

    Authors: Stéphane Stahl, Adelana Santos Stahl, Christoph Meisner, Afshin Rahmanian-Schwarz, Hans-Eberhard Schaller and Oliver Lotter
    Citation: BMC Musculoskeletal Disorders 2012 13:225
  11. Ankle fractures are one of the more commonly occurring forms of trauma managed by orthopaedic teams worldwide. The impacts of these injuries are not restricted to pain and disability caused at the time of the ...

    Authors: Steven M McPhail, Joel Dunstan, Julie Canning and Terry P Haines
    Citation: BMC Musculoskeletal Disorders 2012 13:224
  12. The statutory health insurance system embodies a large amount of data on the treatments of their members. Depending on joint, prosthesis type, patient activity and comorbidity, knee and hip replacements can la...

    Authors: Roland Linder, Hardy Müller, Brigitte Grenz-Farenholtz, Caroline Wagner, Martin Stockheim and Frank Verheyen
    Citation: BMC Musculoskeletal Disorders 2012 13:223
  13. It has been demonstrated that frequency modulation of loading influences cellular response and metabolism in 3D tissues such as cartilage, bone and intervertebral disc. However, the mechano-sensitivity of cell...

    Authors: Thomas H Steiner, Alexander Bürki, Stephen J Ferguson and Benjamin Gantenbein-Ritter
    Citation: BMC Musculoskeletal Disorders 2012 13:222
  14. Age-dependent trabecular changes of the humeral head might weaken the fixation of suture anchors used for rotator cuff (RC) repair. This might lead to suture anchor loosening and thus compromise the integrity ...

    Authors: Chlodwig Kirchhoff, Volker Braunstein, Stefan Milz, Christoph M Sprecher, Sonja Kirchhoff, Mathias Graw, Andreas B Imhoff and Stefan Hinterwimmer
    Citation: BMC Musculoskeletal Disorders 2012 13:221
  15. Joint replacement is an effective intervention for people with advanced arthritis, although there is an important minority of patients who do not improve post-operatively. There is a need for robust evidence o...

    Authors: Vikki Wylde, Ashley W Blom, Stijn Bolink, Luke Brunton, Paul Dieppe, Rachael Gooberman-Hill, Bernd Grimm, Cindy Mann and Erik Lenguerrand
    Citation: BMC Musculoskeletal Disorders 2012 13:220
  16. Gout is the commonest inflammatory arthritis affecting around 1.4% of adults in Europe. It is predominantly managed in primary care and classically affects the joints of the foot, particularly the first metata...

    Authors: Priyanka Chandratre, Christian Mallen, Jane Richardson, Keith Rome, Joanne Bailey, Rajvinder Gill, Samantha Hider, Jane Mason, Zoe Mayson, Sara Muller, Charlotte Purcell, Jennifer Titley, Simon Wathall, Irena Zwierska and Edward Roddy
    Citation: BMC Musculoskeletal Disorders 2012 13:219
  17. Biomarkers of peripheral muscle fatigue (BPMFs) are used to offer insights into mechanisms of exhaustion during exercise in order to detect abnormal fatigue or to detect defective metabolic pathways. This revi...

    Authors: Josef Finsterer
    Citation: BMC Musculoskeletal Disorders 2012 13:218
  18. Bradykinin type 2 receptor (B2BRK) genotype was reported to be associated with changes in the left-ventricular mass as a response to aerobic training, as well as in the regulation of the skeletal muscle performan...

    Authors: Jelena Z Popadic Gacesa, Milica Momcilovic, Igor Veselinovic, David A Brodie and Nikola G Grujic
    Citation: BMC Musculoskeletal Disorders 2012 13:217
  19. Although item response theory (IRT) appears to be increasingly used within health care research in general, a comprehensive overview of the frequency and characteristics of IRT analyses within the rheumatic fi...

    Authors: Liseth Siemons, Peter M ten Klooster, Erik Taal, Cees AW Glas and Mart AFJ Van de Laar
    Citation: BMC Musculoskeletal Disorders 2012 13:216
  20. Clinicians frequently rely on subjective categorization of impairments in mobility, strength, and endurance for clinical decision-making; however, these assessments are often unreliable and lack sensitivity to...

    Authors: Bahar Shahidi, Cynthia L Johnson, Douglas Curran-Everett and Katrina S Maluf
    Citation: BMC Musculoskeletal Disorders 2012 13:215
  21. Intramedullary nailing of pertrochanteric femoral fractures has grown in popularity over the past 2 decades likely because this procedure is associated with a low risk for postoperative morbidity and a fast re...

    Authors: Christian Giessauf, Mathias Glehr, Gerwin A Bernhardt, Franz J Seibert, Karl Gruber, Patrick Sadoghi, Andreas Leithner and Gerald Gruber
    Citation: BMC Musculoskeletal Disorders 2012 13:214
  22. This paper presents the model and results to evaluate the use of teriparatide as a first-line treatment of severe postmenopausal osteoporosis (PMO) and Glucocorticoid-induced osteoporosis (GIOP). The study’s o...

    Authors: Daniel R Murphy, Lee J Smolen, Timothy M Klein and Robert W Klein
    Citation: BMC Musculoskeletal Disorders 2012 13:213
  23. The purpose of the present study was to investigate the radial distribution patterns of cartilage degeneration in dysplastic hips at different stages of secondary osteoarthritis (OA) by using radial delayed ga...

    Authors: Li Xu, Yongbin Su, Karl-Philipp Kienle, Daichi Hayashi, Ali Guermazi, Jing Zhang, Yongming Dai and Xiaoguang Cheng
    Citation: BMC Musculoskeletal Disorders 2012 13:212
  24. Although muscle dysfunction caused by unfamiliar lengthening contraction is one of most important issues in sports medicine, there is little known about the molecular events on regeneration process. The purpos...

    Authors: Hongsun Song, Eisuke Ochi, Kihyuk Lee, Kenji Hiranuma and Koichi Nakazato
    Citation: BMC Musculoskeletal Disorders 2012 13:211
  25. Arm elevation is composed of glenohumeral and scapulothoracic motion. Many reports have addressed changes of scapular position across a spectrum of shoulder disease. However, no study has examined changes in s...

    Authors: Myung-Sun Kim, Keun-Young Lim, Dong-Hyun Lee, David Kovacevic and Nam-Young Cho
    Citation: BMC Musculoskeletal Disorders 2012 13:210
  26. Congenital muscular torticollis (CMT) is a relatively common neck deformity in infancy. The aim of our research was to determine the value of high-frequency and color Doppler ultrasonography in diagnosing CMT.

    Authors: Lei Wang, Lingyan Zhang, Yuanjiao Tang and Li Qiu
    Citation: BMC Musculoskeletal Disorders 2012 13:209
  27. Simvastatin increases the expression of bone morphogenetic protein 2 (BMP-2) in osteoblasts, therefore it is important to investigate the influence of statins on bone formation, fracture healing and implant in...

    Authors: Stephan Pauly, David A Back, Kathrin Kaeppler, Norbert P Haas, Gerhard Schmidmaier and Britt Wildemann
    Citation: BMC Musculoskeletal Disorders 2012 13:208
  28. The single-leg squat (SLS) is a common test used by clinicians for the musculoskeletal assessment of the lower limb. The aim of the current study was to reveal the kinematic parameters used by experienced and ...

    Authors: Benjamin K Weeks, Christopher P Carty and Sean A Horan
    Citation: BMC Musculoskeletal Disorders 2012 13:207
  29. Clinical consequences of alignment errors in total knee replacement (TKR) have led to the rigorous evaluation of surgical alignment techniques. Rotational alignment in the transverse plane has proven particula...

    Authors: Melinda K Harman, Scott A Banks, Stephan Kirschner and Jörg Lützner
    Citation: BMC Musculoskeletal Disorders 2012 13:206
  30. The superiority of tenotomy vs. tenodesis for surgery on lesions of the long head of the biceps brachii tendon is still under debate. Indeed, high-quality evidence is lacking, mainly because of methodological ...

    Authors: Olimpio Galasso, Giorgio Gasparini, Massimo De Benedetto, Filippo Familiari and Roberto Castricini
    Citation: BMC Musculoskeletal Disorders 2012 13:205
  31. The WHO has recently published the FRAX® tool to determine the absolute risk of osteoporotic fracture at 10 years. This tool has not yet been validated in Spain.

    Authors: Rafael Azagra, Genís Roca, Gloria Encabo, Amada Aguyé, Marta Zwart, Sílvia Güell, Núria Puchol, Emili Gene, Enrique Casado, Pilar Sancho, Silvia Solà, Pere Torán, Milagros Iglesias, Maria Carmen Gisbert, Francesc López-Expósito, Jesús Pujol-Salud…
    Citation: BMC Musculoskeletal Disorders 2012 13:204
  32. Multiple studies suggest that reduced postural orientation is a possible risk factor for both patello-femoral joint pain (PFP) and rupture of the anterior cruciate ligament (ACL). In order to prevent PFP and A...

    Authors: Tina Junge, Sølvi Balsnes, Lisbeth Runge, Birgit Juul-Kristensen and Niels Wedderkopp
    Citation: BMC Musculoskeletal Disorders 2012 13:203
  33. Cervicogenic dizziness is a disabling condition characterised by postural unsteadiness that is aggravated by cervical spine movements and associated with a painful and/or stiff neck. Two manual therapy treatme...

    Authors: Susan A Reid, Darren A Rivett, Michael G Katekar and Robin Callister
    Citation: BMC Musculoskeletal Disorders 2012 13:201
  34. Combinations of disease-modifying anti-rheumatic drugs (DMARDs) are increasingly used to control active rheumatoid arthritis (RA); however there is little information about patients’ perspectives, their expect...

    Authors: Heidi Lempp, Darija Hofmann, Stephani L Hatch and David L Scott
    Citation: BMC Musculoskeletal Disorders 2012 13:200
  35. Difficulty sleeping is common among patients with fibromyalgia (FM); however, its impact on health-related quality of life (HRQoL) is not well understood. The aim of the current study was to assess the burden ...

    Authors: Jan-Samuel Wagner, Marco D DiBonaventura, Arthi B Chandran and Joseph C Cappelleri
    Citation: BMC Musculoskeletal Disorders 2012 13:199
  36. Polymethylmethacrylate (PMMA) is commonly used for clinical applications. However, the short handling time increases the probability of a surgeon missing the crucial period in which the cement maintains its id...

    Authors: Po-Liang Lai, Ching-Lung Tai, I-Ming Chu, Tsai-Sheng Fu, Lih-Huei Chen and Wen-Jer Chen
    Citation: BMC Musculoskeletal Disorders 2012 13:198
  37. Hallux valgus (HV) is a very common deformity of the first metatarsophalangeal joint that often requires surgical correction. However, the association between structural HV deformity and related foot pain and ...

    Authors: Sheree E Nix, Bill T Vicenzino and Michelle D Smith
    Citation: BMC Musculoskeletal Disorders 2012 13:197
  38. Work-related musculoskeletal disorders (MSDs) are an important cause of functional impairments and disability among construction workers. An improved understanding of MSDs in different construction occupations...

    Authors: Julitta S Boschman, Henk F van der Molen, Judith K Sluiter and Monique HW Frings-Dresen
    Citation: BMC Musculoskeletal Disorders 2012 13:196
  39. The treatment planning of spine pathologies requires information on the rigidity and permeability of the intervertebral discs (IVDs). Magnetic resonance imaging (MRI) offers great potential as a sensitive and ...

    Authors: Maximilien Recuerda, Delphine Périé, Guillaume Gilbert and Gilles Beaudoin
    Citation: BMC Musculoskeletal Disorders 2012 13:195
  40. Controversy exists regarding the relationship between radiographic findings and clinical status in knee osteoarthritis. Although the surgical indication for total knee arthroplasty (TKA) should be based on pai...

    Authors: Daniel Hernández-Vaquero and José Manuel Fernández-Carreira
    Citation: BMC Musculoskeletal Disorders 2012 13:194
  41. Cerebral palsy (CP) is a posture and movement disorder and different therapeutic modalities, such as the use of braces, have sought to favor selective motor control and muscle coordination in such patients. Th...

    Authors: Hugo Pasini Neto, Luanda André Collange Grecco, Thaluanna CL Christovão, Luiz Alfredo Braun, Lilian Chrystiane Giannasi, Afonso Shiguemi Inoue Salgado, Renata Calhes Franco de Moura, Paulo de Tarso Camillo de Carvalho, João CF Corrêa, Luciana MM Sampaio, Manuela Galli and Claudia Santos Oliveira
    Citation: BMC Musculoskeletal Disorders 2012 13:193
  42. Non-specific chronic low back pain (NSCLBP) is one of the most common musculoskeletal disorders around the world including Iran. One of the most widely used modalities in the field of physiotherapy is therapeu...

    Authors: Safoora Ebadi, Noureddin Nakhostin Ansari, Soofia Naghdi, Shohre Jalaei, Mirmostafa Sadat, Hosein Bagheri, Maurits W vanTulder, Nicholas Henschke and Ehsan Fallah
    Citation: BMC Musculoskeletal Disorders 2012 13:192
  43. Ankylosing spondylitis (AS) is a chronic inflammatory disease of spine and sacroiliac joints; it is characterized by new bone formation, and the disease processes can be accompanied by osteoporosis. In the pre...

    Authors: Ali Taylan, Ismail Sari, Baris Akinci, Safak Bilge, Didem Kozaci, Servet Akar, Ayfer Colak, Hulya Yalcin, Necati Gunay and Nurullah Akkoc
    Citation: BMC Musculoskeletal Disorders 2012 13:191
  44. Estrogens play an important role in modulating the morphology and function of temporomandibular joints (TMJs), which is suggested to act via estrogen receptors (ERs). The present study was to investigate the e...

    Authors: Shibin Yu, Xianghui Xing, Kai Jiao, Lei Sun, Lei Liu and Meiqing Wang
    Citation: BMC Musculoskeletal Disorders 2012 13:190
  45. Self-management programmes (SMP) are recommended for patients with fibromyalgia. The purpose of this study was to evaluate effects of a one week multidisciplinary inpatient self-management programme on psychol...

    Authors: Bente Hamnes, Petter Mowinckel, Ingvild Kjeken and Kåre B Hagen
    Citation: BMC Musculoskeletal Disorders 2012 13:189
  46. Previous studies have described an increased risk of developing tibio-femoral osteoarthritis (TF OA), meniscal tears and bursitis among those with a trade as floor layers. The purpose of this study was to anal...

    Authors: Lilli Kirkeskov Jensen, Søren Rytter and Jens Peter Bonde
    Citation: BMC Musculoskeletal Disorders 2012 13:188
  47. Possible immunization to blood group or other antigens and subsequent inhibition of remodeling or incorporation after use of untreated human bone allograft was described previously. This study presents the imm...

    Authors: Falk Mittag, Matthias Straub, Richard Schäfer, Torsten Kluba and Ingmar Ipach
    Citation: BMC Musculoskeletal Disorders 2012 13:187

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