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  1. Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim of the study was to describethe genome wide DNA methylation changes in hip and knee OA and identify novel genes and pathwaysinvolv...

    Authors: Erfan Aref-Eshghi, Yuhua Zhang, Ming Liu, Patricia E. Harper, Glynn Martin, Andrew Furey, Roger Green, Guang Sun, Proton Rahman and Guangju Zhai
    Citation: BMC Musculoskeletal Disorders 2015 16:287
    Content type: Research article Published on:

  2. Surgical intervention is increasingly performed as the primary treatment of unstable Hangman’s fracture. Some authors have advocated using anterior C2/3 discectomy with interbody fusion and plating to treat un...

    Authors: Fuxin Wei, Le Wang, Zhiyu Zhou, Rui Zhong, Shaoyu Liu, Shangbin Cui, Ximin Pan and Manman Gao
    Citation: BMC Musculoskeletal Disorders 2015 16:285
    Content type: Research article Published on:

  3. Hyaluronic Acid (HA) has been already approved by Food and Drug Administration (FDA) for osteoarthritis (OA), while its use in the treatment of tendinopathy is still debated. The aim of this study was to evalu...

    Authors: Leonardo Osti, Martina Berardocco, Viviana di Giacomo, Graziella Di Bernardo, Francesco Oliva and Anna C. Berardi
    Citation: BMC Musculoskeletal Disorders 2015 16:284
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2015 16:334

  5. K wire fixation with tension band wiring has conventionally been used for the open reduction and internal fixation of the patella. However, it suffers from distinct disadvantages such as implant irritation, ne...

    Authors: Tao Lin, Junbin Liu, Baojun Xiao, Dehao Fu and Shuhua Yang
    Citation: BMC Musculoskeletal Disorders 2015 16:282
    Content type: Research article Published on:

  6. Legg-Calve-Perthes Disease (LCPD) is an idiopathic osteonecrosis of the developing femoral head complicated by pain and disability of the hip joint. To date, the pathological mechanisms of LCPD are not well-kn...

    Authors: Ruiyu Liu, Lihong Fan, Longbin Yin, Kunzheng Wang, Wusheng Miao, Qichun Song, Xiaoqian Dang, Hang Gao and Chuanyi Bai
    Citation: BMC Musculoskeletal Disorders 2015 16:281
    Content type: Research article Published on:

  7. Arthroscopic glenohumeral debridement for symptom control has shown promising short term results in the young active population, when arthroplasty may not be a practical option due to the recommended activity ...

    Authors: Patrick Henry, Helen Razmjou, Tim Dwyer, Jesse A. Slade Shantz and Richard Holtby
    Citation: BMC Musculoskeletal Disorders 2015 16:280
    Content type: Research article Published on:

  8. The ability to predict preoperatively the identity of patients undergoing hip arthroplasty at risk of suboptimal outcomes could help implement interventions targeted at improving surgical results. The objectiv...

    Authors: Eugen Lungu, Pascal-André Vendittoli and François Desmeules
    Citation: BMC Musculoskeletal Disorders 2015 16:279
    Content type: Research article Published on:

  9. Immune thrombocytopenia (ITP) is an immune-mediated acquired disease that is characterized by a decrease in the platelet count and an increased risk of bleeding. There is little information in the literature a...

    Authors: Seung-Jae Lim, Ingwon Yeo, Chan-Woo Park, Young-Wan Moon and Youn-Soo Park
    Citation: BMC Musculoskeletal Disorders 2015 16:278
    Content type: Research article Published on:

  10. Death certificates can be used to assess disease prevalence and incidence; however, rheumatoid arthritis (RA) often remains unreported in death certificates. We sought to determine to what extent RA is underre...

    Authors: Emily Molina, Inmaculada del Rincon, Jose Felix Restrepo, Daniel F. Battafarano and Agustin Escalante
    Citation: BMC Musculoskeletal Disorders 2015 16:277
    Content type: Research article Published on:

  11. Although a few studies on perioperative stroke following spinal surgery have been reported, differences in the incidence of perioperative stroke among various surgical procedures have not been determined. The ...

    Authors: Junichi Ohya, Hirotaka Chikuda, Takeshi Oichi, Hiromasa Horiguchi, Katsushi Takeshita, Sakae Tanaka and Hideo Yasunaga
    Citation: BMC Musculoskeletal Disorders 2015 16:276
    Content type: Research article Published on:

  12. Conventional stemmed anatomical shoulder prostheses are widely used in the treatment of glenohumeral osteoarthritis. The stemless shoulder prosthesis, in contrast, is a new concept, and fewer outcome studies a...

    Authors: Michael W. Maier, Sarah Lauer, Matthias C. Klotz, Matthias Bülhoff, David Spranz and Felix Zeifang
    Citation: BMC Musculoskeletal Disorders 2015 16:275
    Content type: Research article Published on:

  13. To develop services, healthcare professionals must make business cases to managerial bodies within Hospital Trusts and if approved, to commissioning bodies. Patients with hip fracture are at high risk of subse...

    Authors: Sarah Drew, Rachael Gooberman-Hill, Andrew Farmer, Laura Graham, M Kassim Javaid, Cyrus Cooper and Andrew Judge
    Citation: BMC Musculoskeletal Disorders 2015 16:274
    Content type: Research article Published on:

  14. Work-related musculoskeletal disorders (WMSD) is the most expensive form of work disability. Female sex has been considered as an individual risk factor for the development of WMSD, specifically in the neck an...

    Authors: Amir K. Vafadar, Julie N. Côté and Philippe S. Archambault
    Citation: BMC Musculoskeletal Disorders 2015 16:273
    Content type: Research article Published on:

  15. Whereas synovitis is one of most common findings during arthroscopic surgery in patients with rotator cuff diseases, no study has investigated its characteristics. We propose a macroscopic assessment system fo...

    Authors: Chris H. Jo, Ji Sun Shin, Ji Eun Kim and Sohee Oh
    Citation: BMC Musculoskeletal Disorders 2015 16:272
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2015 16:380

  16. The single-leg squat (SLS) test is widely used in screening for musculoskeletal injury risk. Little is known, however, of lower limb, pelvis, and trunk kinematics of SLS performance or the effect of sex and fa...

    Authors: Benjamin K. Weeks, Christopher P. Carty and Sean A. Horan
    Citation: BMC Musculoskeletal Disorders 2015 16:271
    Content type: Research article Published on:

  17. It is believed that phosphocitrate (PC) exerts its disease-modifying effects on osteoarthritis (OA) by inhibiting the formation of crystals. However, recent findings suggest that PC exerts its disease-modifyin...

    Authors: Yubo Sun, Nikkole Haines, Andrea Roberts, Michael Ruffolo, David R. Mauerhan, Kim L. Mihalko, Jane Ingram, Michael Cox and Edward N. Hanley Jr
    Citation: BMC Musculoskeletal Disorders 2015 16:270
    Content type: Research article Published on:

  18. Osteoporosis is a complication of rheumatoid arthritis (RA). We identified risk factors for osteoporosis during treatment with biologics.

    Authors: Kengo Takahashi, Takao Setoguchi, Hiroki Tawaratsumida, Yoshiya Arishima, Hiroyuki Tominaga, Yasuhiro Ishidou, Satoshi Nagano, Sanae Shigemizu, Noriko Aoki, Masaki Akimoto, Hideo Otsubo, Takemasa Matsuda, Hironori Kakoi, Toshihiko Izumi, Shunsuke Nakamura, Masahiro Yokouchi…
    Citation: BMC Musculoskeletal Disorders 2015 16:269
    Content type: Research article Published on:

  19. Clinical disease activity index (CDAI) and simplified disease activity index (SDAI) are useful tools for the evaluation of disease activity in patients with rheumatoid arthritis (RA), but have not been compara...

    Authors: Imane Ben Slama, Fadoua Allali, Touria Lakhdar, Sarra El kabbaj, Lamyae Medrare, Ange Ngeuleu, Hanan Rkain and Najia Hajjaj - Hassouni
    Citation: BMC Musculoskeletal Disorders 2015 16:268
    Content type: Research article Published on:

  20. Anterior cervical decompression and fusion (ACDF) has long been the preferred treatment for cervical spondylotic myelopathy (CSM). However, few studies have focused on surgical results of CSM in patients with ...

    Authors: Jing Tao Zhang, Lin Feng Wang, Yue Ju Liu, Jun Ming Cao, Jie Li, Shuai Wang and Yong Shen
    Citation: BMC Musculoskeletal Disorders 2015 16:267
    Content type: Research article Published on:

  21. The goal of this study was to biomechanically assess tibial rotation in the knee joint simultaneous changes in rotation of large joints of the lower limbs and pelvis during gait in patients during early postop...

    Authors: Andrzej Czamara, Iga Markowska and Magdalena Hagner-Derengowska
    Citation: BMC Musculoskeletal Disorders 2015 16:266
    Content type: Research article Published on:

  23. Physical activity improves pain and function among individuals with knee osteoarthritis (OA), but most people with this condition are inactive. Physical therapists play a key role in helping people with knee O...

    Authors: Quinn I. Williams, Alexander H. Gunn, John E. Beaulieu, Bernadette C. Benas, Bruce Buley, Leigh F. Callahan, John Cantrell, Andrew P. Genova, Yvonne M. Golightly, Adam P. Goode, Christopher I. Gridley, Michael T. Gross, Bryan C. Heiderscheit, Carla H. Hill, Kim M. Huffman, Aaron Kline…
    Citation: BMC Musculoskeletal Disorders 2015 16:264
    Content type: Study protocol Published on:

  25. Malignant bone tumors of the lower extremity are more frequently found in children and adolescents than in adults. Modern treatment regimens led to high limb salvage rates and offer the choice between endopros...

    Authors: Guntmar Gradl, Lukas K. Postl, Ulrich Lenze, Josef Stolberg-Stolberg, Florian Pohlig, Hans Rechl, Markus Schmitt-Sody, Ruediger von Eisenhart-Rothe and Chlodwig Kirchhoff
    Citation: BMC Musculoskeletal Disorders 2015 16:262
    Content type: Research article Published on:

  26. The transoral atlantoaxial reduction plate (TARP) fixation has been introduced to achieve reduction, decompression, fixation and fusion of C1–C2 through a transoral-only approach. However, it may also be assoc...

    Authors: Bao-cheng Zhang, Hai-bo Liu, Xian-hua Cai, Zhi-hua Wang, Feng Xu, Hui Kang, Ran Ding and Xiao-qing Luo
    Citation: BMC Musculoskeletal Disorders 2015 16:261
    Content type: Research article Published on:

  27. For many women with Rheumatoid Arthritis (RA) motherhood decisions are complicated by their condition and complex pharmacological treatments. Decisions about having children or expanding their family require r...

    Authors: T. Meade, E. Dowswell, N. Manolios and L. Sharpe
    Citation: BMC Musculoskeletal Disorders 2015 16:260
    Content type: Research article Published on:

  28. Osteopetrosis is an uncommon, inherited disease, characterized by osteosclerosis, obliteration of the medullary canal, calcified cartilage and brittle bone due to impaired osteoclast resorption. Osteoarthritis...

    Authors: Lin Xie, Fan Ding, Jing Jiao, Wusheng Kan and Junwen Wang
    Citation: BMC Musculoskeletal Disorders 2015 16:259
    Content type: Case report Published on:

  29. Prior studies describing the treatment of symptomatic knee osteoarthritis with injections of bone marrow concentrate have provided encouraging results. The relationship between the cellular dose contained with...

    Authors: Christopher J. Centeno, Hasan Al-Sayegh, Jamil Bashir, Shaun Goodyear and Michael D. Freeman
    Citation: BMC Musculoskeletal Disorders 2015 16:258
    Content type: Research article Published on:

  30. To examine the longitudinal utility of a biomarker signature in conjunction with myositis autoantibodies (autoAbs) as predictors of disease improvement in refractory myositis patients treated with rituximab.

    Authors: Ann M. Reed, Cynthia S. Crowson, Molly Hein, Consuelo Lopez de Padilla, Jeannette M. Olazagasti, Rohit Aggarwal, Dana P. Ascherman, Marc C. Levesque and Chester V. Oddis
    Citation: BMC Musculoskeletal Disorders 2015 16:257
    Content type: Research article Published on:

  31. Authors: Sandra García-Padilla, Miguel Angel Duarte-Vázquez, Karla Elena Gonzalez-Romero, María del Carmen Caamaño and Jorge L Rosado
    Citation: BMC Musculoskeletal Disorders 2015 16:256
    Content type: Erratum Published on:

    The original article was published in BMC Musculoskeletal Disorders 2015 16:114

  32. Implant-related osteomyelitis is a major complication that requires immediate treatment, often involving removal of the implant, prolonging patient recovery and inflating expenses. Current research involving i...

    Authors: Stefanie M. Shiels, Katherine M. Bedigrew and Joseph C. Wenke
    Citation: BMC Musculoskeletal Disorders 2015 16:255
    Content type: Research article Published on:

  33. Osteomyelitis is a challenge for orthopaedic surgeons. There is a lack of scientific evidence to guide treatment. The purpose of this study was to report the clinical outcome of unplanned retention of antibiot...

    Authors: Xu-Sheng Qiu, Xin Zheng, Hong-fei Shi, Yan-cheng Zhu, Xia Guo, Hai-jun Mao, Guang-yue Xu and Yi-xin Chen
    Citation: BMC Musculoskeletal Disorders 2015 16:254
    Content type: Research article Published on:

  34. The psychometric properties of Patient Reported Outcomes Measurement Information System (PROMIS) instruments have been explored in a number of general and clinical samples. No study, however, has evaluated the...

    Authors: Jeffrey B. Driban, Nani Morgan, Lori Lyn Price, Karon F. Cook and Chenchen Wang
    Citation: BMC Musculoskeletal Disorders 2015 16:253
    Content type: Research article Published on:

  35. Osteoarthritis (OA) is a highly prevalent and disabling disease. It is estimated that by 2030 the prevalence of symptomatic OA could reach 30 % of the population above 60 years. This randomised controlled tria...

    Authors: Sarah Rubia Ferreira de Meneses, David John Hunter, Eunice Young Docko and Amelia Pasqual Marques
    Citation: BMC Musculoskeletal Disorders 2015 16:252
    Content type: Study protocol Published on:

  36. To date, there has been no studies to evaluate the incidence of Crohn’s disease in systemic sclerosis patients. The goals of this study were to evaluate the incidence of Crohn’s disease and its relationship wi...

    Authors: Chia-Chun Tseng, Jeng-Hsien Yen, Wen-Chan Tsai, Tsan-Teng Ou, Cheng-Chin Wu, Wan-Yu Sung, Ming-Chia Hsieh and Shun-Jen Chang
    Citation: BMC Musculoskeletal Disorders 2015 16:251
    Content type: Research article Published on:

  37. Abrasion arthroplasty (AAP) is a procedure by which intrinsic cartilage healing is believed to be stimulated. Although clinically accepted for degenerative and traumatic cartilage lesions scientific evidence a...

    Authors: Rainer Beckmann, Sebastian Lippross, Claudia Hartz, Mersedeh Tohidnezhad, Mónica S. Ventura Ferreira, Sabine Neuss-Stein, Andreas Seekamp, Sven Nebelung, Nisreen Kweider, Björn Rath, Holger Jahr, Thomas Pufe and Deike J. Varoga
    Citation: BMC Musculoskeletal Disorders 2015 16:250
    Content type: Research article Published on:

  38. The optimal type of bearing for hip arthroplasty remains a matter of debate. Ceramic-on-polyethylene (CoP) bearings are frequently used in younger and more active patients to reduce wear and increase biocompat...

    Authors: Nicholas A. Beckmann, Tobias Gotterbarm, Moritz M. Innmann, Christian Merle, Thomas Bruckner, J. Philippe Kretzer and Marcus R. Streit
    Citation: BMC Musculoskeletal Disorders 2015 16:249
    Content type: Research article Published on:

  39. Subacromial shoulder pain is a common complaint. Radial Extracorporeal Shock Wave Therapy (rESWT) has being increasingly used to treat calcific and non-calcific tendinosis, although there is no evidence of the...

    Authors: Elisabeth Kvalvaag, Jens Ivar Brox, Kaia Beck Engebretsen, Helene Lundgaard Søberg, Erik Bautz-Holter and Cecilie Røe
    Citation: BMC Musculoskeletal Disorders 2015 16:248
    Content type: Study protocol Published on:

  40. Recent research has focused on identifying chemical modulators of osteogenesis. We present initial findings on the osteoinductive properties of prostaglandin Е1 (Vasaprostan), using a rabbit model.

    Authors: Pawel V. Lipinsky, Ivan V. Sirotin, Alexandr V. Skoroglyadov, Alexey V. Ivkov, Alexandr P. Oettinger, Evgeny E. Krynetskiy, Alexandr B. But-Gusaim and Andreas J. Roth
    Citation: BMC Musculoskeletal Disorders 2015 16:247
    Content type: Research article Published on:

  41. The aim of this study was to clarify pain, quality of life and activity in the aged evacuees living in temporary housing after the Great East Japan Earthquake on 11 March 2011.

    Authors: Shoji Yabuki, Kazuo Ouchi, Shin-ichi Kikuchi and Shin-ichi Konno
    Citation: BMC Musculoskeletal Disorders 2015 16:246
    Content type: Research article Published on:

  42. Increasing utilization of primary total knee arthroplasty (TKA) is projected to expand demand for revision TKA. Revision TKAs are procedurally complex and incur high costs on our financially constrained health...

    Authors: Benedict U. Nwachukwu, Ellen B. Gurary, Vladislav Lerner, Jamie E. Collins, Thomas S. Thornhill, Elena Losina and Jeffrey N. Katz
    Citation: BMC Musculoskeletal Disorders 2015 16:245
    Content type: Research article Published on:

  43. Dipeptidyl peptidase-IV (DPP-IV) is suggested to contribute to the pathogenesis of several autoimmune diseases. The aim of this study was to evaluate the association of DPP-IV presence in blood plasma and mono...

    Authors: Lucie Sromova, Petr Busek, Liliana Sedova and Aleksi Sedo
    Citation: BMC Musculoskeletal Disorders 2015 16:244
    Content type: Research article Published on:

  44. Timely rheumatologic referral and management are crucial for patients with potential inflammatory arthritis. To meet this need, tools such as the early inflammatory arthritis (EIA) detection tool was developed...

    Authors: Ming-Chi Lu, Malcolm Koo and Ning-Sheng Lai
    Citation: BMC Musculoskeletal Disorders 2015 16:243
    Content type: Research article Published on:

  47. Due to complex pelvic geometry, percutaneous screw placement in the posterior acetabular column can pose a major challenge even for experienced surgeons.

    Authors: Bjoern Gunnar Ochs, Fabian Maria Stuby, Ulrich Stoeckle and Christoph Emanuel Gonser
    Citation: BMC Musculoskeletal Disorders 2015 16:240
    Content type: Research article Published on:

  48. Patient-generated health outcome measures are important in the assessment of long-term treatment goals for Rheumatoid Arthritis (RA), but few psychometrically sound measures are available. The MAPLe-RA (Measuring...

    Authors: Fowzia Ibrahim, Salma Ayis, Darija Hofmann, Diana Rose, Til Wykes, Andrew Cope, David L. Scott and Heidi Lempp
    Citation: BMC Musculoskeletal Disorders 2015 16:239
    Content type: Research article Published on:

  49. The coracoacromial ligament (CAL) is an important restraint to superior shoulder translation. CAL release with the Latarjet procedure leads to increased superior humeral translation. Therefore, a surgical tech...

    Authors: Matthias Aurich, Gunther O. Hofmann and Florian Gras
    Citation: BMC Musculoskeletal Disorders 2015 16:238
    Content type: Research article Published on:

  50. High tibial osteotomy (HTO) with a medially opening wedge has been used to treat osteoarthritic knees. However, the osteotomized tibia becomes a highly unstable structure and necessitates the use of plate and ...

    Authors: Chu-An Luo, Su-Yang Hwa, Shang-Chih Lin, Chun-Ming Chen and Ching-Shiow Tseng
    Citation: BMC Musculoskeletal Disorders 2015 16:235
    Content type: Research article Published on:
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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