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  1. Back, neck and shoulder pain are the most common causes of occupational disability. They reduce health-related quality of life and have a significant economic impact. Many different forms of physical treatment...

    Authors: Pedro Serrano-Aguilar, Francisco M Kovacs, Jose M Cabrera-Hernández, Juan M Ramos-Goñi and Lidia García-Pérez
    Citation: BMC Musculoskeletal Disorders 2011 12:287
  2. There is a lack of knowledge about the pattern of symptom reporting in the general population as most research focuses on specific diseases or symptoms. The number of musculoskeletal pain sites is a strong pre...

    Authors: Hedda Tschudi-Madsen, Mona Kjeldsberg, Bård Natvig, Camilla Ihlebaek, Ingvild Dalen, Yusman Kamaleri, Jørund Straand and Dag Bruusgaard
    Citation: BMC Musculoskeletal Disorders 2011 12:285
  3. Hip dislocation is a serious complication among children with cerebral palsy (CP). The aim of this study was to compare the prevalence of hip dislocation among children with CP in an area providing regular car...

    Authors: Areej I Elkamil, Guro L Andersen, Gunnar Hägglund, Torarin Lamvik, Jon Skranes and Torstein Vik
    Citation: BMC Musculoskeletal Disorders 2011 12:284
  4. Oxidative stress due to the overproduction of nitric oxide (NO) and other oxygen reactive species (ROS), play a main role in the initiation and progression of the OA disease and leads to the degeneration of mi...

    Authors: Mercedes Fernández-Moreno, María Tamayo, Angel Soto-Hermida, Alejandro Mosquera, Natividad Oreiro, Carlos Fernández-López, José Luis Fernández, Ignacio Rego-Pérez and Francisco J Blanco
    Citation: BMC Musculoskeletal Disorders 2011 12:283
  5. The Subacromial Impingement Syndrome (SIS) is the most common diagnosed disorder of the shoulder in primary health care, but its aetiology is unclear. Conservative treatment regimes focus at reduction of subac...

    Authors: Pieter Bas de Witte, Jochem Nagels, Ewoud RA van Arkel, Cornelis PJ Visser, Rob GHH Nelissen and Jurriaan H de Groot
    Citation: BMC Musculoskeletal Disorders 2011 12:282
  6. Unicameral (or simple) bone cysts (UBC) are benign tumours most often located in long bones of children and adolescents. Pathological fractures are common, and due to high recurrence rates, these lesions remai...

    Authors: Sébastien Hagmann, Florian Eichhorn, Babak Moradi, Tobias Gotterbarm, Thomas Dreher, Burkhard Lehner and Felix Zeifang
    Citation: BMC Musculoskeletal Disorders 2011 12:281
  7. Recent international guidelines recommend intra-articular corticosteroid injections for patients with hip osteoarthritis who have moderate to severe pain and do not respond satisfactorily to oral analgesic/ant...

    Authors: Desirée MJ Dorleijn, Pim AJ Luijsterburg, Max Reijman, Margreet Kloppenburg, Jan AN Verhaar, Patrick JE Bindels, P Koen Bos and Sita MA Bierma-Zeinstra
    Citation: BMC Musculoskeletal Disorders 2011 12:280
  8. FTY720 (Fingolimod) is a novel immunosuppressive drug investigated in clinical trials for organ transplantation and multiple sclerosis. It acts as a functional sphingosine-1-phosphate (S1P) receptor antagonist...

    Authors: Martin H Stradner, Hannes Angerer, Thomas Ortner, Florentine C Fuerst, Daniela Setznagl, Marie-Luise Kremser, Josef Hermann and Winfried B Graninger
    Citation: BMC Musculoskeletal Disorders 2011 12:279
  9. After the Food and Drug Administration Modernization Act of 1997, the registration of all clinical trials became mandatory prior to publication. Our primary objective was to determine publication rates for ort...

    Authors: Rajiv Gandhi, Meryam Jan, Holly N Smith, Nizar N Mahomed and Mohit Bhandari
    Citation: BMC Musculoskeletal Disorders 2011 12:278
  10. To cope at their homes, community-dwelling older people surviving a hip fracture need a sufficient amount of functional ability and mobility. There is a lack of evidence on the best practices supporting recove...

    Authors: Sarianna Sipilä, Anu Salpakoski, Johanna Edgren, Ari Heinonen, Markku A Kauppinen, Marja Arkela-Kautiainen, Sanna E Sihvonen, Maija Pesola, Taina Rantanen and Mauri Kallinen
    Citation: BMC Musculoskeletal Disorders 2011 12:277
  11. Osteoarthritis of the knee involving predominantly the medial tibiofemoral compartment is common in older people, giving rise to pain and loss of function. Many people experience progressive worsening of the d...

    Authors: Kim L Bennell, Thorlene Egerton, Tim V Wrigley, Paul W Hodges, Michael Hunt, Ewa M Roos, Mary Kyriakides, Ben Metcalf, Andrew Forbes, Eva Ageberg and Rana S Hinman
    Citation: BMC Musculoskeletal Disorders 2011 12:276
  12. Currently, herniated nucleus pulposus (HNP) with radiculopathy and other preconditions are regarded as relative or absolute contraindications for lumbar total disc replacement (TDR). In Switzerland it is left ...

    Authors: Thomas Zweig, Christoph Hemmeler, Emin Aghayev, Markus Melloh, Christian Etter and Christoph Röder
    Citation: BMC Musculoskeletal Disorders 2011 12:275
  13. Many patients suffer from chronic neck pain following a whiplash injury. A combination of cognitive, behavioural therapy with physiotherapy interventions has been indicated to be effective in the management of...

    Authors: Inge Ris Hansen, Karen Søgaard, Robin Christensen, Bente Thomsen, Claus Manniche and Birgit Juul-Kristensen
    Citation: BMC Musculoskeletal Disorders 2011 12:274
  14. Several symptom-relieving interventions have been shown to be efficacious among osteoarthritis (OA) patients with knee effusion; however, not every symptomatic knee OA patient has clinical effusion. Results ma...

    Authors: Nicole M Cattano, Jeffrey B Driban, Easwaran Balasubramanian, Mary F Barbe, Mamta Amin and Michael R Sitler
    Citation: BMC Musculoskeletal Disorders 2011 12:273
  15. The European Project on OSteoArthritis (EPOSA), here presented for the first time, is a collaborative study involving five European cohort studies on aging. This project focuses on the personal and societal bu...

    Authors: Laura A Schaap, Geeske MEE Peeters, Elaine M Dennison, Sabina Zambon, Thorsten Nikolaus, Mercedes Sanchez-Martinez, Estella Musacchio, Natasja M van Schoor and Dorly JH Deeg
    Citation: BMC Musculoskeletal Disorders 2011 12:272
  16. Osteoporosis and associated fractures are a major public health burden and there is great need for a large animal model. Melatonin, the hormone of the pineal gland, has been shown to influence bone metabolism....

    Authors: Marcus Egermann, Christian Gerhardt, Alain Barth, Georges J Maestroni, Erich Schneider and Mauro Alini
    Citation: BMC Musculoskeletal Disorders 2011 12:271
  17. Hip osteoarthritis (hip OA) is a disease with a major impact on both national economy and the patients themselves. Patients suffer from pain and functional impairment in activities of daily life which are asso...

    Authors: Inga Krauss, Benjamin Steinhilber, Georg Haupt, Regina Miller, Stefan Grau and Pia Janssen
    Citation: BMC Musculoskeletal Disorders 2011 12:270
  18. The objective of the study was to determine whether psychological and social factors predict the course of limitations in activities in elderly patients with osteoarthritis of the hip or knee, in addition to e...

    Authors: Gabriella M van Dijk, Cindy Veenhof, Guus J Lankhorst, Cornelia HM van den Ende and Joost Dekker
    Citation: BMC Musculoskeletal Disorders 2011 12:269
  19. The aim of this study was to investigate whether pressure pain hyperalgesia is a feature of professional pianists suffering from neck pain as their main playing-related musculoskeletal disorder.

    Authors: Marcela Linari-Melfi, Irene Cantarero-Villanueva, Carolina Fernández-Lao, César Fernández-de-las-Peñas, Rafael Guisado-Barrilao and Manuel Arroyo-Morales
    Citation: BMC Musculoskeletal Disorders 2011 12:268
  20. This study aimed to establish the profile and the evolution of an early Rheumatoid arthritis (RA) cohort in the Moroccan population and also to search possible predictor factors of structural progression.

    Authors: Karima Benbouazza, Bahia Benchekroun, Hanan Rkain, Bouchra Amine, Fatiha Bzami, Leila Benbrahim, Ouafa Atouf, Malika Essakalli, Redouane Abouqal, Maxime Dougados and Najia Hajjaj-Hassouni
    Citation: BMC Musculoskeletal Disorders 2011 12:266
  21. Severe arthritis of the knee is a disabling condition, with over 50,000 knee replacements performed each year in the UK. Isolated patellofemoral joint arthritis occurs in over 10% of these patients with the tr...

    Authors: Michelle Odumenya, Katie McGuinness, Juul Achten, Nick Parsons, Tim Spalding and Matthew Costa
    Citation: BMC Musculoskeletal Disorders 2011 12:265
  22. Oxidative stress play a main role in the initiation and progression of the OA disease and leads to the degeneration of mitochondria. To prevent this, the chondrocytes possess a well-coordinated enzymatic antio...

    Authors: Mercedes Fernandez-Moreno, Angel Soto-Hermida, Sonia Pertega, Natividad Oreiro, Carlos Fernandez-Lopez, Ignacio Rego-Perez and Francisco J Blanco
    Citation: BMC Musculoskeletal Disorders 2011 12:264
  23. Enhancing osteogenic capabilities of bone matrix for the treatment of fractures and segmental defects using growth factors is an active area of research. Recently, synthetic peptides like AC- 100, TP508 or p-1...

    Authors: Thomas Vordemvenne, Jürgen RJ Paletta, Rene Hartensuer, Thomas Pap, Michael J Raschke and Sabine Ochman
    Citation: BMC Musculoskeletal Disorders 2011 12:263
  24. Anemia is more often seen in older patients. As the mean age of hip fracture patients is rising, anemia is common in this population. Allogeneic blood transfusion (ABT) and anemia have been pointed out as poss...

    Authors: Anne JH Vochteloo, Boudewijn LS Borger van der Burg, Bart JA Mertens, Arthur HP Niggebrugge, Mark R de Vries, Wim E Tuinebreijer, Rolf M Bloem, Rob GHH Nelissen and Peter Pilot
    Citation: BMC Musculoskeletal Disorders 2011 12:262
  25. This multicenter, open-label, prospective, single cohort study evaluated the effectiveness and safety of adalimumab in a clinical setting reflecting the Canadian standard of care for the treatment of patients ...

    Authors: Boulos Haraoui, Alfred Cividino, Jacqueline Stewart, Benoît Guérette and Edward C Keystone
    Citation: BMC Musculoskeletal Disorders 2011 12:261
  26. This work aimed to study the homing evidence and the reparative effect of mesenchymal stem cells (MSCs) in the healing process of induced osteoarthritis in experimental animal model (donkeys).

    Authors: Abir N Mokbel, Omar S El Tookhy, Ashraf A Shamaa, Laila A Rashed, Dina Sabry and Abeer M El Sayed
    Citation: BMC Musculoskeletal Disorders 2011 12:259
  27. Fibromyalgia (FM) is a heterogeneous syndrome and its classification into subgroups calls for broad-based discussion. FM subgrouping, which aims to adapt treatment according to different subgroups, relies in p...

    Authors: Bernard Auvinet, Denis Chaleil, Jean Cabane, Anne Dumolard, Pierre Hatron, Robert Juvin, Michel Lanteri-Minet, Yves Mainguy, Laurence Negre-Pages, Fabien Pillard, Daniel Riviere and Yves-Michel Maugars
    Citation: BMC Musculoskeletal Disorders 2011 12:258
  28. Osteoarthritis (OA) is a prevalent progressive musculoskeletal disorder, leading to pain and disability. Patient information and education are considered core elements in treatment guidelines for OA; however, ...

    Authors: Rikke H Moe, Espen A Haavardsholm, Margreth Grotle, Eldri Steen, Ingvild Kjeken, Kåre Birger Hagen and Till Uhlig
    Citation: BMC Musculoskeletal Disorders 2011 12:257
  29. Currently, custom foot and ankle orthosis prescription and design tend to be based on traditional techniques, which can result in devices which vary greatly between clinicians and repeat prescription. The use ...

    Authors: Michiel Oosterwaal, Scott Telfer, Søren Tørholm, Sylvain Carbes, Lodewijk W van Rhijn, Ross Macduff, Kenneth Meijer and Jim Woodburn
    Citation: BMC Musculoskeletal Disorders 2011 12:256
  30. This study aimed to investigate the reliability and construct validity of the International Classification of Functioning, Disability and Health (ICF) Comprehensive Core Set for osteoarthritis (OA) in order to...

    Authors: Yeşim Kurtaiş, Derya Őztuna, Ayşe A Küçükdeveci, Şehim Kutlay, Meliha Hafiz and Alan Tennant
    Citation: BMC Musculoskeletal Disorders 2011 12:255
  31. Hip fracture is associated with high mortality. Cardiovascular disease and other comorbidities requiring long-term anticoagulant medication are common in these mostly elderly patients. The objective of our obs...

    Authors: Annika M Kragh, Markus Waldén, Anna Apelqvist, Philippe Wagner and Isam Atroshi
    Citation: BMC Musculoskeletal Disorders 2011 12:254
  32. The epidemiology of acute orthopedic dislocations is poorly understood. A nationwide database provides a valuable resource for examining this issue in the Taiwanese population.

    Authors: Nan-Ping Yang, Hou-Chaung Chen, Dinh-Van Phan, I-Liang Yu, Yi-Hui Lee, Chien-Lung Chan, Pesus Chou and Jenn-Huei Renn
    Citation: BMC Musculoskeletal Disorders 2011 12:253
  33. There has been increasing focus on factors predicting the development of chronic musculoskeletal disorders. For patients already experiencing chronic non-specific low back pain it is also relevant to investiga...

    Authors: Karin Verkerk, Pim AJ Luijsterburg, Inge Ronchetti, Harald S Miedema, Annelies Pool-Goudzwaard, Jan-Paul van Wingerden and Bart W Koes
    Citation: BMC Musculoskeletal Disorders 2011 12:252
  34. Knee size and body size differ in Asians compared with Caucasians. Nevertheless, many total knee arthroplasty (TKA) prostheses used worldwide are made for Western Caucasian subjects. As a result, an Asian's kn...

    Authors: Kunihiro Hosaka, Shu Saito, Takao Ishii, Sei Mori, Takanobu Sumino and Yasuaki Tokuhashi
    Citation: BMC Musculoskeletal Disorders 2011 12:251
  35. Plasma d-dimer levels have been associated with the status of tumor progression or oncological outcomes in cancer. Although there are many evidences suggesting the involvement of procoagulant trend in musculos...

    Authors: Takeshi Morii, Kazuo Mochizuki, Takashi Tajima, Shoichi Ichimura and Kazuhiko Satomi
    Citation: BMC Musculoskeletal Disorders 2011 12:250
  36. Patients undergoing total knee arthroplasty (TKA) often experience strength deficits both pre- and post-operatively. As these deficits may have a direct impact on functional recovery, strength assessment shoul...

    Authors: Ian FH Koblbauer, Yannick Lambrecht, Micheline LM van der Hulst, Camille Neeter, Raoul HH Engelbert, Rudolf W Poolman and Vanessa A Scholtes
    Citation: BMC Musculoskeletal Disorders 2011 12:249
  37. Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus int...

    Authors: Katja Bloecker, Martin Englund, Wolfgang Wirth, Martin Hudelmaier, Rainer Burgkart, Richard B Frobell and Felix Eckstein
    Citation: BMC Musculoskeletal Disorders 2011 12:248
  38. Current treatments for the prevention of thromboembolism include heparin and low-molecular weight heparins (LMWHs). A number of studies have suggested that long term administration of these drugs may adversely...

    Authors: Gandhi N Solayar, Pauline M Walsh and Kevin J Mulhall
    Citation: BMC Musculoskeletal Disorders 2011 12:247
  39. Age-related sarcopenia is a disease state of loss of muscle mass and strength that affects physical function and mobility leading to falls, fractures, and disability. The need for therapies to treat age-relate...

    Authors: Chi-Sung Chiu, Hans Weber, Sharon Adamski, Albert Rauch, Michael A Gentile, Stephen E Alves, Gary Kath, Osvaldo Flores and Hilary A Wilkinson
    Citation: BMC Musculoskeletal Disorders 2011 12:246
  40. Several clinical measures of sensory and motor function are used alongside patient-rated questionnaires to assess outcomes of carpal tunnel decompression. However there is a lack of evidence regarding which cl...

    Authors: Christina Jerosch-Herold, Lee Shepstone, Leanne Miller and Peter Chapman
    Citation: BMC Musculoskeletal Disorders 2011 12:244
  41. The Manchester Foot Pain and Disability Index (MFPDI) has been used to determine the prevalence of disabling foot pain in several studies, however there is some debate as to which case definition is most appro...

    Authors: Hylton B Menz, Tiffany K Gill, Anne W Taylor and Catherine L Hill
    Citation: BMC Musculoskeletal Disorders 2011 12:243
  42. The aims were to explore bone mineral density (BMD) by digital X-ray radiogrammetry (DXR) in postmenopausal women with long-lasting rheumatoid arthritis (RA) in relation to dual x-ray absorptiometry (DXA)-BMD,...

    Authors: Helena Forsblad-d'Elia and Hans Carlsten
    Citation: BMC Musculoskeletal Disorders 2011 12:242
  43. Joint pain is a highly prevalent condition in the older population. Only a minority of the older adults consult the general practitioner for joint pain, and during consultation joint pain is often poorly recog...

    Authors: Lotte AH Hermsen, Stephanie S Leone, Daniëlle AWM van der Windt, Martin Smalbrugge, Joost Dekker and Henriëtte E van der Horst
    Citation: BMC Musculoskeletal Disorders 2011 12:241
  44. Cyclosprin A (CsA) has been widely used clinically to treat the patients who have undergone organ transplantation or acquired autoimmune disease. The purpose of this study is to determine the effects of three ...

    Authors: Yixin Chen, Xin Zheng, Rui Zou and Junfei Wang
    Citation: BMC Musculoskeletal Disorders 2011 12:240
  45. Fusion of lumbar spine segments is a well-established therapy for many pathologies. The procedure changes the biomechanics of the spine. Initial clinical benefits may be outweighed by ensuing damage to the adj...

    Authors: Jan Siewe, Christina Otto, Peter Knoell, Marco Koriller, Gregor Stein, Thomas Kaulhausen, Peer Eysel, Kourosh Zarghooni, Jeremy Franklin and Rolf Sobottke
    Citation: BMC Musculoskeletal Disorders 2011 12:239
  46. Acute trauma of the wrist is one of the most frequent reasons for visiting the Emergency Department. These patients are routinely referred for radiological examination. Most X-rays however, do not reveal any f...

    Authors: Abdelali Bentohami, Monique MJ Walenkamp, Annelie Slaar, M Suzan H Beerekamp, Joris AH de Groot, Eva M Verhoog, L Cara Jager, Mario Maas, Taco S Bijlsma, Bart A van Dijkman, Niels WL Schep and J C Goslings
    Citation: BMC Musculoskeletal Disorders 2011 12:238

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2013 14:95

  47. Hsp90β is a member of the Hsp90 family of protein chaperones. This family plays essential roles in the folding, maturation and activity of many proteins that are involved in signal transduction and transcripti...

    Authors: Valentina Calamia, Maria C de Andrés, Natividad Oreiro, Cristina Ruiz-Romero and Francisco J Blanco
    Citation: BMC Musculoskeletal Disorders 2011 12:237

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