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  1. Obesity is the most modifiable risk factor, and dietary induced weight loss potentially the best nonpharmacologic intervention to prevent or to slow osteoarthritis (OA) disease progression. We are currently co...

    Authors: Stephen P Messier, Claudine Legault, Shannon Mihalko, Gary D Miller, Richard F Loeser, Paul DeVita, Mary Lyles, Felix Eckstein, David J Hunter, Jeff D Williamson and Barbara J Nicklas

    Citation: BMC Musculoskeletal Disorders 2009 10:93

    Content type: Study protocol

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  2. Rotator cuff tendinopathy and subacromial impingement syndrome present complex patomechanical situations, frequent difficulties in clinical diagnosis and lack of effectiveness in treatment. Based on clinical e...

    Authors: Sara Perez-Palomares, Bárbara Oliván-Blázquez, Ana Mª Arnal-Burró, Orlando Mayoral-Del Moral, Elena Gaspar-Calvo, Mª Luisa de-la-Torre-Beldarraín, Elena López-Lapeña, Marina Pérez-Benito, Victoria Ara-Loriente and Laura Romo-Calvo

    Citation: BMC Musculoskeletal Disorders 2009 10:92

    Content type: Study protocol

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  3. No definitive data are available regarding the value of switching to an alternative TNF antagonist in rheumatoid arthritis patients who fail to respond to the first one. The aim of this study was to evaluate t...

    Authors: Federico Navarro-Sarabia, Dolores Ruiz-Montesinos, Blanca Hernandez, Victoria Navarro-Compán, Sara Marsal, Mireia Barcelo, Eva Perez-Pampín and Juan J Gómez-Reino

    Citation: BMC Musculoskeletal Disorders 2009 10:91

    Content type: Research article

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  4. The management of Whiplash Associated Disorders is one of the most complicated challenges with high expenses for the health care system and society. There are still no general guidelines or scientific document...

    Authors: Anne Söderlund, Annika Bring and Pernilla Åsenlöf

    Citation: BMC Musculoskeletal Disorders 2009 10:90

    Content type: Study protocol

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  5. Musculoskeletal disorders (MSDs) are an important cause for morbidity in military service. They result in disabilities needing long-term rehabilitation and functional impairment leading to premature discharge ...

    Authors: Henri Taanila, Jaana Suni, Harri Pihlajamäki, Ville M Mattila, Olli Ohrankämmen, Petteri Vuorinen and Jari Parkkari

    Citation: BMC Musculoskeletal Disorders 2009 10:89

    Content type: Research article

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  6. Previous osteotomy may compromise subsequent knee replacement, but no guidelines considering knee arthroplasty after prior osteotomy have been developed. We describe a systematic review of non-randomized studi...

    Authors: Tom M van Raaij, Max Reijman, Andrea D Furlan and Jan AN Verhaar

    Citation: BMC Musculoskeletal Disorders 2009 10:88

    Content type: Research article

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  7. An inconsistent relationship between physical activity and neck/shoulder pain (NSP) in adolescents has been reported in the literature. Earlier studies may be limited by not assessing physical activity in suff...

    Authors: Andrew M Briggs, Leon M Straker, Natasha L Bear and Anne J Smith

    Citation: BMC Musculoskeletal Disorders 2009 10:87

    Content type: Research article

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  8. In case of contraindications or intolerance during treatment with oral bisphosphonates (OB), administration of pamidronate intravenously is a widely used alternative.

    Authors: Danielle A Eekman, Marijn Vis, Irene EM Bultink, Harm JGM Derikx, Ben AC Dijkmans and Willem F Lems

    Citation: BMC Musculoskeletal Disorders 2009 10:86

    Content type: Research article

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  9. Involvement of users in health care research is central to UK health care policy, and guidelines for involvement exist. However, there are limited examples in rheumatology research. The aim of this study was t...

    Authors: Clare Jinks, Bie Nio Ong and Tracey J O'Neill

    Citation: BMC Musculoskeletal Disorders 2009 10:85

    Content type: Correspondence

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  10. Little is known about future sick-leave diagnoses among individuals on long-term sickness absence. The aim of this study was to describe the panorama of sick-leave diagnoses over time among young adults initia...

    Authors: Marjan Vaez, Jan Hagberg and Kristina Alexanderson

    Citation: BMC Musculoskeletal Disorders 2009 10:84

    Content type: Research article

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  11. Osteochondral talar defects usually affect athletic patients. The primary surgical treatment consists of arthroscopic debridement and microfracturing. Although this is mostly successful, early sport resumption...

    Authors: Christiaan JA van Bergen, Leendert Blankevoort, Rob J de Haan, Inger N Sierevelt, Duncan E Meuffels, Pieter RN d'Hooghe, Rover Krips, Geert van Damme and C Niek van Dijk

    Citation: BMC Musculoskeletal Disorders 2009 10:83

    Content type: Study protocol

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  12. Chronic pelvic pain (CPP) is a lower abdominal pain lasting at least 6 months, occurring continuously or intermittently and not associated exclusively with menstruation or intercourse. Although the musculoskel...

    Authors: Mary LLS Montenegro, Elaine CL Mateus-Vasconcelos, Júlio C Rosa e Silva, Francisco J Candido dos Reis, Antonio A Nogueira and Omero B Poli-Neto

    Citation: BMC Musculoskeletal Disorders 2009 10:82

    Content type: Research article

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  13. Vertebral endplate signal changes (VESC) are more common among patients with low back pain (LBP) and/or sciatica than in people who are not seeking care for back pain. The distribution and characteristics of V...

    Authors: Tue S Jensen, Tom Bendix, Joan S Sorensen, Claus Manniche, Lars Korsholm and Per Kjaer

    Citation: BMC Musculoskeletal Disorders 2009 10:81

    Content type: Research article

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  14. Some risk factors for low-energy wrist fracture have been identified. However, self-reported measures such as health-related quality of life (HRQOL) have not been examined as potential risk factors for wrist f...

    Authors: Gudrun Rohde, Anne M Mengshoel, Astrid K Wahl, Torbjorn Moum and Glenn Haugeberg

    Citation: BMC Musculoskeletal Disorders 2009 10:80

    Content type: Research article

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  15. Chronic low back pain (CLBP) is a persistent disabling condition with rising significant healthcare, social and economic costs. Current research supports the use of exercise-based treatment approaches that enc...

    Authors: Deirdre A Hurley, Grainne O'Donoghue, Mark A Tully, Jennifer Klaber Moffett, Willem van Mechelen, Leslie Daly, Colin AG Boreham and Suzanne M McDonough

    Citation: BMC Musculoskeletal Disorders 2009 10:79

    Content type: Study protocol

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  16. Fibromyalgia (FM) is characterised by diffuse musculoskeletal pain and stiffness at multiple sites, tender points in characteristic locations, and the frequent presence of symptoms such as fatigue. The aim of ...

    Authors: Roberto Casale, Piercarlo Sarzi-Puttini, Fabiola Atzeni, Marco Gazzoni, Dan Buskila and Alberto Rainoldi

    Citation: BMC Musculoskeletal Disorders 2009 10:78

    Content type: Research article

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  17. Thoracic spine pain (TSP) is experienced across the lifespan by healthy individuals and is a common presentation in primary healthcare clinical practice. However, the epidemiological characteristics of TSP are...

    Authors: Andrew M Briggs, Anne J Smith, Leon M Straker and Peter Bragge

    Citation: BMC Musculoskeletal Disorders 2009 10:77

    Content type: Research article

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  18. Corticosteroid injection and physiotherapy are two commonly prescribed interventions for management of lateral epicondylalgia. Corticosteroid injections are the most clinically efficacious in the short term bu...

    Authors: Brooke K Coombes, Leanne Bisset, Luke B Connelly, Peter Brooks and Bill Vicenzino

    Citation: BMC Musculoskeletal Disorders 2009 10:76

    Content type: Study protocol

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  19. Knee injuries in football are common regardless of age, gender or playing level, but adolescent females seem to have the highest risk. The consequences after severe knee injury, for example anterior cruciate l...

    Authors: Martin Hägglund, Markus Waldén and Isam Atroshi

    Citation: BMC Musculoskeletal Disorders 2009 10:75

    Content type: Study protocol

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  20. In the literature there are discussions on the choice of outcome and the need for more longitudinal studies of musculoskeletal disorders. The general aim of this longitudinal study was to analyze musculoskelet...

    Authors: Anna Grimby-Ekman, Eva M Andersson and Mats Hagberg

    Citation: BMC Musculoskeletal Disorders 2009 10:73

    Content type: Research article

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  21. Dupuytren's Disease (DD) is a debilitating contractile fibrosis of the palmar fascia characterised by excess collagen deposition, contractile myofibroblast development, increased Transforming Growth Factor-β l...

    Authors: Linda Vi, Anna Njarlangattil, Yan Wu, Bing Siang Gan and David B O'Gorman

    Citation: BMC Musculoskeletal Disorders 2009 10:72

    Content type: Research article

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  22. Early and intensive treatment is important to inducing remission and preventing joint damage in patients with rheumatoid arthritis. While intensive combination therapy (Disease Modifying Anti-rheumatic Drugs a...

    Authors: Susanne JJ Claessen, Johanna MW Hazes, Margriet AM Huisman, Derkjen van Zeben, Jolanda J Luime and Angelique EAM Weel

    Citation: BMC Musculoskeletal Disorders 2009 10:71

    Content type: Study protocol

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  23. Intra-articular adhesion (IA) is one of the important pathologic signs of intracapsular temporomandibular joint (TMJ) diseases, but this factor has been rarely described with respect to its arthroscopic charac...

    Authors: ShanYong Zhang, XiuMing Li u, Chi Yang, XieYi Cai, MinJie Chen, Majd S Haddad, Bai Yun and ZhuoZhi Chen

    Citation: BMC Musculoskeletal Disorders 2009 10:70

    Content type: Research article

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  24. There is little scientific evidence to support the usual practice of providing outpatient rehabilitation to patients undergoing total knee replacement surgery (TKR) immediately after discharge from the orthopa...

    Authors: Chung-Wei Christine Lin, Lyn March, Jack Crosbie, Ross Crawford, Stephen Graves, Justine Naylor, Alison Harmer, Stephen Jan, Kim Bennell, Ian Harris, David Parker, Helene Moffet and Marlene Fransen

    Citation: BMC Musculoskeletal Disorders 2009 10:69

    Content type: Study protocol

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  25. The Work Instability Scale for Rheumatoid Arthritis (RA-WIS) is established and is used by physicians to identify patients at risk of job loss for rapid intervention. The study objective was to explore the con...

    Authors: Gill Gilworth, Paul Emery, Nick Barkham, M Glyn Smyth, Philip Helliwell and Alan Tennant

    Citation: BMC Musculoskeletal Disorders 2009 10:68

    Content type: Research article

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  26. Alterations in the feet of patients with rheumatoid arthritis (RA) are a cause of disability in this population. The purpose of this research was to evaluate the impact that foot impairment has on the patients...

    Authors: Adriana Rojas-Villarraga, Javier Bayona, Natalia Zuluaga, Santiago Mejia, Maria-Eugenia Hincapie and Juan-Manuel Anaya

    Citation: BMC Musculoskeletal Disorders 2009 10:67

    Content type: Research article

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  27. We conducted the present study to investigate the therapeutic effects of a combination treatment of alfacalcidol (ALF) and risedronate (RIS) on the bone mechanical properties of bone and calcium (Ca) metabolis...

    Authors: Ayako Shiraishi, Sayaka Miyabe, Takayoshi Nakano, Yukichi Umakoshi, Masako Ito and Masahiko Mihara

    Citation: BMC Musculoskeletal Disorders 2009 10:66

    Content type: Research article

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  28. Despite over 2 decades of research, the ability to prevent work-related low back pain (LBP) and disability remains elusive. Recent research suggests that interventions that are focused at the workplace and inc...

    Authors: Carlo Ammendolia, David Cassidy, Ivan Steenstra, Sophie Soklaridis, Eleanor Boyle, Stephanie Eng, Hamer Howard, Bains Bhupinder and Pierre Côté

    Citation: BMC Musculoskeletal Disorders 2009 10:65

    Content type: Research article

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  29. The aim of this study was to estimate the prevalence of fibromyalgia, as well as to assess the major symptoms of this syndrome in an adult, low socioeconomic status population assisted by the primary health ca...

    Authors: Ana Assumpção, Alane B Cavalcante, Cristina E Capela, Juliana F Sauer, Suellen D Chalot, Carlos AB Pereira and Amélia P Marques

    Citation: BMC Musculoskeletal Disorders 2009 10:64

    Content type: Research article

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  30. Repetitive and stressful work tasks have been linked to the development of pain in the trapezius muscle, although the underlying mechanisms still remain unclear. In earlier studies, it has been hypothesized th...

    Authors: Anna Sjörs, Britt Larsson, Joakim Dahlman, Torbjörn Falkmer and Björn Gerdle

    Citation: BMC Musculoskeletal Disorders 2009 10:63

    Content type: Research article

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  31. While musculoskeletal problems are leading sources of disability, there has been little research on measuring the number of functionally limiting musculoskeletal problems for use as predictor of outcome in stu...

    Authors: Jeffrey N Katz, Elizabeth A Wright, John A Baron and Elena Losina

    Citation: BMC Musculoskeletal Disorders 2009 10:62

    Content type: Research article

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  32. Articular cartilage is a viscoelastic material, but its exact behaviour under the full range of physiological loading frequencies is unknown. The objective of this study was to measure the viscoelastic propert...

    Authors: Geoffrey R Fulcher, David WL Hukins and Duncan ET Shepherd

    Citation: BMC Musculoskeletal Disorders 2009 10:61

    Content type: Research article

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  33. Low bone mass is common in end-stage renal disease patients, especially those undergoing hemodialysis. It can lead to serious bone health problems such as fragility fractures. The purpose of this study is to i...

    Authors: Guey-Shiun Huang, Tzong-Shinn Chu, Meei-Fang Lou, Shiow-Li Hwang and Rong-Sen Yang

    Citation: BMC Musculoskeletal Disorders 2009 10:60

    Content type: Research article

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  34. Aseptic loosening (AL) is the main problem of total joints replacement (TJR) by the implantation of permanently prosthetic components. In vitro and in vivo studies have clearly demonstrated that wear debris an...

    Authors: Gang Li, Ping Wu, Yao Xu, Yan Yu, Li Sun, Liang Zhu and Duyun Ye

    Citation: BMC Musculoskeletal Disorders 2009 10:57

    Content type: Research article

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  35. A discussion is ongoing whether displaced femoral neck fractures in elderly patients should be treated with a non-cemented or a cemented hemiarthroplasty. A recent Cochrane analysis stresses the importance of ...

    Authors: Anne JH Vochteloo, DieuDonné Niesten, Roeland Riedijk, Willard J Rijnberg, Stefan BT Bolder, Sander Koëter, Keetie Kremers-van de Hei, Taco Gosens and Peter Pilot

    Citation: BMC Musculoskeletal Disorders 2009 10:56

    Content type: Study protocol

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  36. Low back pain persisting for longer than 3 months is a common and costly condition for which many current treatments have low-moderate success rates at best. Exercise is among the more successful treatments fo...

    Authors: Amanda M Hall, Chris G Maher, Jane Latimer, Manuela L Ferreira and Paul Lam

    Citation: BMC Musculoskeletal Disorders 2009 10:55

    Content type: Study protocol

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  37. Diabetes is becoming one of the most common chronic diseases, and ulcers are its most serious complication. Beginning with neuropathy, the subsequent foot wounds frequently lead to lower extremity amputation, ...

    Authors: Biagio Moretti, Angela Notarnicola, Giulio Maggio, Lorenzo Moretti, Michele Pascone, Silvio Tafuri and Vittorio Patella

    Citation: BMC Musculoskeletal Disorders 2009 10:54

    Content type: Research article

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  38. A relatively high incidence of pathological conditions in retrieved femoral heads, including a group of patients having low grade B-cell lymphoma, has been described before. At short term follow up none of the...

    Authors: Eline W Zwitser, Arthur de Gast, Mirjam JA Basie, Folkert J van Kemenade and Barend J van Royen

    Citation: BMC Musculoskeletal Disorders 2009 10:53

    Content type: Research article

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  39. Recent evidences show that education and rehabilitation while waiting for knee replacement have positive effects on the patients' health status. Identification of factors associated with worse pain, function a...

    Authors: François Desmeules, Clermont E Dionne, Étienne Belzile, Renée Bourbonnais and Pierre Frémont

    Citation: BMC Musculoskeletal Disorders 2009 10:52

    Content type: Research article

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  40. Osteoblasts are considered to primarily arise from osseous progenitors within the periosteum or bone marrow. We have speculated that cells from local soft tissues may also take on an osteogenic phenotype. Myob...

    Authors: Renjing Liu, Samantha L Ginn, Monkol Lek, Kathryn N North, Ian E Alexander, David G Little and Aaron Schindeler

    Citation: BMC Musculoskeletal Disorders 2009 10:51

    Content type: Research article

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  41. Rheumatic diseases commonly affect joints and other structures in the hand. Surgery is a traditional way to treat hand problems in inflammatory rheumatic diseases with the purposes of pain relief, restore func...

    Authors: Gunnel Sandqvist, Pia Malcus Johnsson, Anna-Lena Sturesson, Magnus Tägil and Pierre Geborek

    Citation: BMC Musculoskeletal Disorders 2009 10:50

    Content type: Research article

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  42. The usual surgical treatment of refractory sciatica caused by lumbar disc herniation, is open discectomy. Minimally invasive procedures, including percutaneous therapies under local anesthesia, are increasingl...

    Authors: Patrick A Brouwer, Wilco C Peul, Ronald Brand, Mark P Arts, Bart W Koes, Annette A van den Berg and Mark A van Buchem

    Citation: BMC Musculoskeletal Disorders 2009 10:49

    Content type: Study protocol

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  43. The to date evidence for a dose-response relationship between physical workload and the development of lumbar disc diseases is limited. We therefore investigated the possible etiologic relevance of cumulative ...

    Authors: Andreas Seidler, Annekatrin Bergmann, Matthias Jäger, Rolf Ellegast, Dirk Ditchen, Gine Elsner, Joachim Grifka, Johannes Haerting, Friedrich Hofmann, Oliver Linhardt, Alwin Luttmann, Martina Michaelis, Gabriela Petereit-Haack, Barbara Schumann and Ulrich Bolm-Audorff

    Citation: BMC Musculoskeletal Disorders 2009 10:48

    Content type: Research article

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  44. despite evidence of an obesity-related disability, there is a lack of objective muscle functional data in overweight subjects. Only few studies provide instrumental strength measurements in non-syndromal obesi...

    Authors: Paolo Capodaglio, Luca Vismara, Francesco Menegoni, Gabriele Baccalaro, Manuela Galli and Graziano Grugni

    Citation: BMC Musculoskeletal Disorders 2009 10:47

    Content type: Research article

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  45. A critical component of disease progression in rheumatoid arthritis (RA) involves neovascularization associated with pannus formation. 2-methoxyestradiol (2ME2) is a naturally occurring molecule with no known ...

    Authors: Stacy M Plum, Eun J Park, Steve J Strawn, Elizabeth G Moore, Carolyn F Sidor and William E Fogler

    Citation: BMC Musculoskeletal Disorders 2009 10:46

    Content type: Research article

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  46. Bombina variegate peptide 8 (Bv8) is a small protein secreted by frog skin. Recently it has been shown to contribute to tumor angiogenesis in mouse model. The purpose of this study was to investigate Bv8 in mice...

    Authors: Daitaro Kurosaka, Kentaro Noda, Ken Yoshida, Kazuhiro Furuya, Taro Ukichi, Eigo Takahashi, Maimi Yanagimachi, Isamu Kingetsu, Saburo Saito and Akio Yamada

    Citation: BMC Musculoskeletal Disorders 2009 10:45

    Content type: Research article

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  47. This study was designed to derive the theoretical formulae to predict the pullout strength of pedicle screws with an inconstant outer and/or inner diameter distribution (conical screws). For the transpedicular...

    Authors: Wen-Chi Tsai, Po-Quang Chen, Tung-Wu Lu, Shing-Sheng Wu, Kao-Shang Shih and Shang-Chih Lin

    Citation: BMC Musculoskeletal Disorders 2009 10:44

    Content type: Research article

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