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  1. Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been of diagnostic value in Northern European Caucasian patients with rheumatoid arthritis (RA). In these populations, anti-CCP antibodies are assoc...

    Authors: Ioannis Alexiou, Anastasios Germenis, Athanasios Ziogas, Katerina Theodoridou and Lazaros I Sakkas

    Citation: BMC Musculoskeletal Disorders 2007 8:37

    Content type: Research article

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  2. Plantar heel pain is one of the most common musculoskeletal disorders of the foot and ankle. Treatment of the condition is usually conservative, however the effectiveness of many treatments frequently used in ...

    Authors: Joel A Radford, Karl B Landorf, Rachelle Buchbinder and Catherine Cook

    Citation: BMC Musculoskeletal Disorders 2007 8:36

    Content type: Research article

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  3. Training of neuromuscular control has become increasingly important and plays a major role in rehabilitation of subjects with an injury to the anterior cruciate ligament (ACL). Little is known, however, of the...

    Authors: Anette von Porat, Marketta Henriksson, Eva Holmström and Ewa M Roos

    Citation: BMC Musculoskeletal Disorders 2007 8:35

    Content type: Research article

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  4. Health service policy in the United Kingdom emphasises the importance of self-care by patients with chronic conditions. Written information for patients about their condition is seen as an important aid to hel...

    Authors: Janet C Grime and Bie Nio Ong

    Citation: BMC Musculoskeletal Disorders 2007 8:34

    Content type: Research article

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  5. A conceptual model of lateral muscular tension in patients presenting thyroid associated ophthalmopathy (TAO) has been recently described. Clinical improvement has been achieved by using acupuncture on points ...

    Authors: Roy Moncayo, Ansgar Rudisch, Christian Kremser and Helga Moncayo

    Citation: BMC Musculoskeletal Disorders 2007 8:33

    Content type: Research article

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  6. In the rehabilitation of patients with prolonged back and neck pain, the physical impairment should be assessed. Previous research has exclusively engaged medically educated examiners, mostly physiotherapists....

    Authors: Odd Lindell, Lars Eriksson and Lars-Erik Strender

    Citation: BMC Musculoskeletal Disorders 2007 8:31

    Content type: Research article

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  7. Musculoskeletal impairment (MSI) is an important cause of morbidity and mortality worldwide, especially in developing countries. Prevalence studies for MSI in the developing world have used varying methodologi...

    Authors: Oluwarantimi Atijosan, Hannah Kuper, Dorothea Rischewski, Victoria Simms and Christopher Lavy

    Citation: BMC Musculoskeletal Disorders 2007 8:30

    Content type: Research article

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  8. Sphingosine-1-phosphate (S1P), a downstream metabolite of ceramide, induces various bioactivities via two distinct pathways: as an intracellular second messenger or through receptor activation. The receptor fo...

    Authors: Kayo Masuko, Minako Murata, Hiroshi Nakamura, Kazuo Yudoh, Kusuki Nishioka and Tomohiro Kato

    Citation: BMC Musculoskeletal Disorders 2007 8:29

    Content type: Research article

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  9. Lumbosacral fusion is a relatively common procedure that is used in the management of an unstable spine. The anterior interbody cage has been involved to enhance the stability of a pedicle screw construct used...

    Authors: Shih-Hao Chen, Ruey Mo Lin, Hsiang-Ho Chen and Kai-Jow Tsai

    Citation: BMC Musculoskeletal Disorders 2007 8:28

    Content type: Research article

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  10. This study explored the feasibility of using an Internet survey of people with fibromyalgia (FM), with a view to providing information on demographics, sources of information, symptoms, functionality, perceive...

    Authors: Robert M Bennett, Jessie Jones, Dennis C Turk, I Jon Russell and Lynne Matallana

    Citation: BMC Musculoskeletal Disorders 2007 8:27

    Content type: Research article

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  11. Long thoracic nerve injury leading to scapular winging is common, often caused by closed trauma through compression, stretching, traction, direct extrinsic force, penetrating injury, or neuritides such as Pars...

    Authors: Rahul K Nath, Andrew B Lyons and Gabriel Bietz

    Citation: BMC Musculoskeletal Disorders 2007 8:25

    Content type: Research article

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  12. Running is a popular form of recreational exercise. Beside the positive effects of running on health and fitness, the risk of a running related injury has to be considered. The incidence of injuries in runners...

    Authors: Ida Buist, Steef W Bredeweg, Koen APM Lemmink, Gert-Jan Pepping, Johannes Zwerver, Willem van Mechelen and Ron L Diercks

    Citation: BMC Musculoskeletal Disorders 2007 8:24

    Content type: Study protocol

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  13. Hydrotherapy is highly valued by people with rheumatoid arthritis yet few studies have compared the benefits of exercises in heated water against exercises on land. In particular, data on quality of life is ra...

    Authors: Lis Eversden, Fiona Maggs, Peter Nightingale and Paresh Jobanputra

    Citation: BMC Musculoskeletal Disorders 2007 8:23

    Content type: Research article

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  14. Primary patellofemoral dislocations are common. In most patients, non-operative management produces satisfactory outcome. If the dislocation recurs after a trial of rehabilitation, operative intervention is co...

    Authors: Michael R Carmont and Nicola Maffulli

    Citation: BMC Musculoskeletal Disorders 2007 8:22

    Content type: Technical advance

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  15. Different interventions can reduce the burden of the chronic low back pain. One example is the use of a 'Back School Programme'. This is a brief therapy that uses a health education method to empower participa...

    Authors: Sedigheh Sadat Tavafian, Ahmadreza Jamshidi, Kazem Mohammad and Ali Montazeri

    Citation: BMC Musculoskeletal Disorders 2007 8:21

    Content type: Research article

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  16. Ankylosing spondylitis is a chronic inflammatory rheumatic disorder which usually begins in early adulthood. The diagnosis is often delayed by many years. MR imaging has become the preferred imaging method for...

    Authors: Ulrich Weber, Christian WA Pfirrmann, Rudolf O Kissling, Juerg Hodler and Marco Zanetti

    Citation: BMC Musculoskeletal Disorders 2007 8:20

    Content type: Research article

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  17. Manipulation is a common treatment for non-specific neck pain. Neck manipulation, unlike gentler forms of manual therapy such as mobilisation, is associated with a small risk of serious neurovascular injury an...

    Authors: Andrew M Leaver, Kathryn M Refshauge, Christopher G Maher, Jane Latimer, Rob D Herbert, Gwendolen Jull and James H McAuley

    Citation: BMC Musculoskeletal Disorders 2007 8:18

    Content type: Study protocol

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  18. Low level connective tissue inflammation has been proposed to play a role in thyroid associated ophthalmopathy (TAO). The aim of this study was to investigate this postulate by a musculoskeletal approach toget...

    Authors: Roy Moncayo and Helga Moncayo

    Citation: BMC Musculoskeletal Disorders 2007 8:17

    Content type: Research article

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  19. Tendinosis lesions show an increase of glycosaminoglycan amount, calcifications, and lipid accumulation. Therefore, altered cellular differentiation might play a role in the etiology of tendinosis. This study ...

    Authors: Marieke de Mos, Wendy JLM Koevoet, Holger Jahr, Monique MA Verstegen, Marinus P Heijboer, Nicole Kops, Johannes PTM van Leeuwen, Harrie Weinans, Jan AN Verhaar and Gerjo JVM van Osch

    Citation: BMC Musculoskeletal Disorders 2007 8:16

    Content type: Research article

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  20. Subacromial impingement syndrome (SIS) is the most frequently recorded shoulder disorder. When conservative treatment of SIS fails, a subacromial decompression is warranted. However, the best moment of referra...

    Authors: Oscar Dorrestijn, Martin Stevens, Ron L Diercks, Klaas van der Meer and Jan C Winters

    Citation: BMC Musculoskeletal Disorders 2007 8:15

    Content type: Study protocol

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  21. Low back pain (LBP) is a major public health problem. Risk factors for the development and persistence of LBP include physical and psychological factors. However, most research activity has focused on physical...

    Authors: Sarah E Lamb, Ranjit Lall, Zara Hansen, Emma J Withers, Frances E Griffiths, Ala Szczepura, Julie Barlow and Martin R Underwood

    Citation: BMC Musculoskeletal Disorders 2007 8:14

    Content type: Study protocol

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  22. It is not clear whether bone turnover markers can be used to make inference regarding changes in bone mineral density (BMD) in untreated healthy elderly men. The present study was designed to address three spe...

    Authors: Tuan V Nguyen, Christian Meier, Jacqueline R Center, John A Eisman and Markus J Seibel

    Citation: BMC Musculoskeletal Disorders 2007 8:13

    Content type: Research article

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  23. Osteoporosis, a disease of decreased bone mineral density represents a significant and growing burden in the western world. Aging population structure and therapeutic use of glucocorticoids have contributed in...

    Authors: Conor J Hurson, Joseph S Butler, Dominic T Keating, David W Murray, Denise M Sadlier, John M O'Byrne and Peter P Doran

    Citation: BMC Musculoskeletal Disorders 2007 8:12

    Content type: Research article

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  24. Although clinical guidelines generally portray chronic low back pain as a condition with a poor prognosis this portrayal is based on studies of potentially unrepresentative survival cohorts. The aim of this st...

    Authors: Luciola da Cunha Menezes Costa, Nicholas Henschke, Christopher G Maher, Kathryn M Refshauge, Robert D Herbert, James H McAuley, Anurina Das and Leonardo OP Costa

    Citation: BMC Musculoskeletal Disorders 2007 8:11

    Content type: Study protocol

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  25. In many countries, community pharmacists can be consulted without appointment in a large number of convenient locations. They are in an ideal position to give advice to patients at the onset of low back pain a...

    Authors: Jonathan Silcock, Jennifer Klaber Moffett, Hilary Edmondson, Gordon Waddell and A Kim Burton

    Citation: BMC Musculoskeletal Disorders 2007 8:10

    Content type: Research article

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  26. Older workers have a higher rate and cost of injury than younger workers and with a rapidly ageing work force there is a need to identify strategies to address this problem. Older workers are less physically a...

    Authors: Martin Mackey, Chris G Maher, Terry Wong and Kathleen Collins

    Citation: BMC Musculoskeletal Disorders 2007 8:9

    Content type: Study protocol

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  27. Altered spinal mobility is thought to be related to current or past episodes of low back pain; however evidence of that relationship in younger subjects has not been established. The purpose of this study was ...

    Authors: Kornelia Kulig, Christopher M Powers, Robert F Landel, Hungwen Chen, Michael Fredericson, Marc Guillet and Kim Butts

    Citation: BMC Musculoskeletal Disorders 2007 8:8

    Content type: Research article

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  28. A substantial proportion of patients with whiplash injuries develop chronic symptoms. However, the best treatment of acute injuries to prevent long-term problems is uncertain. A stepped care treatment pathway ...

    Authors: Sarah E Lamb, Simon Gates, Martin R Underwood, Matthew W Cooke, Deborah Ashby, Ala Szczepura, Mark A Williams, Esther M Williamson, Emma J Withers, Shahrul Mt Isa and Anil Gumber

    Citation: BMC Musculoskeletal Disorders 2007 8:7

    Content type: Study protocol

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  29. The assessment of outcomes from the patient's perspective becomes more recognized in health care. Also in patients with chronic ankle instability, the degree of present impairments, disabilities and participat...

    Authors: Christophe Eechaute, Peter Vaes, Lieve Van Aerschot, Sara Asman and William Duquet

    Citation: BMC Musculoskeletal Disorders 2007 8:6

    Content type: Research article

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  30. Moderate to severe osteoarthrosis is the most common indication for Total Hip Arthroplasty (THA). Minimally Invasive Total Hip Surgery (MIS) and computer-navigated surgery were introduced several years ago. Ho...

    Authors: Inge HF Reininga, Robert Wagenmakers, Inge van den Akker-Scheek, A Dennis Stant, Johan W Groothoff, Sjoerd K Bulstra, Wiebren Zijlstra and Martin Stevens

    Citation: BMC Musculoskeletal Disorders 2007 8:4

    Content type: Study protocol

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  31. It is still unclear whether addition of calcium/vitamin D supplements leads to an incremental benefit in patients taking bisphosphonates and whether achievement of serum level of 25 (OH) vitamin D of at least ...

    Authors: Andrew Deane, Leonor Constancio, Ignac Fogelman and Geeta Hampson

    Citation: BMC Musculoskeletal Disorders 2007 8:3

    Content type: Research article

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  32. The overall rate of operations after recurrent lumbar disc herniation has been shown to be 3–11%. However, little is known about the rate of residives. Thus the aim of this study was to explore the cumulative ...

    Authors: Arja Häkkinen, Ilkka Kiviranta, Marko H Neva, Hannu Kautiainen and Jari Ylinen

    Citation: BMC Musculoskeletal Disorders 2007 8:2

    Content type: Research article

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  33. Angiogenesis appears to be a first-order event in psoriatic arthritis (PsA). Among angiogenic factors, the cytokines vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and fibroblast gro...

    Authors: Christopher Butt, Sooyeol Lim, Celia Greenwood and Proton Rahman

    Citation: BMC Musculoskeletal Disorders 2007 8:1

    Content type: Research article

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  34. Previous clinical studies have documented successful neck pain relief in whiplash patients using nerve block and radiofrequency ablation of facet joint afferents, including capsular ligament nerves. No previou...

    Authors: Yasuhiro Tominaga, Anthony B Ndu, Marcus P Coe, Arnold J Valenson, Paul C Ivancic, Shigeki Ito, Wolfgang Rubin and Manohar M Panjabi

    Citation: BMC Musculoskeletal Disorders 2006 7:103

    Content type: Research article

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  35. Foot involvement occurs early in rheumatoid arthritis but the extent to which this impacts on the structure and function leading to impairment and foot related disability is unknown. The purpose of this study ...

    Authors: Deborah E Turner, Philip S Helliwell, Paul Emery and James Woodburn

    Citation: BMC Musculoskeletal Disorders 2006 7:102

    Content type: Research article

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  36. In the context of finite health resources, encouraging self-management of chronic conditions is important. Indeed, it is a key priority in the UK. An increasing number of self-management programmes are becomin...

    Authors: Jane L Carr, Jennifer A Klaber Moffett, Donald M Sharp and Derek R Haines

    Citation: BMC Musculoskeletal Disorders 2006 7:101

    Content type: Research article

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  37. Information on early recovery after arthroplasty is needed to help benchmark progress and make appropriate decisions concerning patient rehabilitation needs. The purpose of this study was to model early recove...

    Authors: Deborah M Kennedy, Paul W Stratford, Steven E Hanna, Jean Wessel and Jeffrey D Gollish

    Citation: BMC Musculoskeletal Disorders 2006 7:100

    Content type: Research article

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  38. COMP (Cartilage oligomeric matrix protein) is a matrix protein, which is currently studied as a potential serum marker for cartilage processes in osteoarthritis (OA). The influence of physical exercise on seru...

    Authors: Maria LE Andersson, Carina A Thorstensson, Ewa M Roos, Ingemar F Petersson, Dick Heinegård and Tore Saxne

    Citation: BMC Musculoskeletal Disorders 2006 7:98

    Content type: Research article

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  39. Shoulder pain is common in primary care, and has an unfavourable outcome in many patients. Information about predictors of shoulder pain related sick leave in workers is scarce and inconsistent. The objective ...

    Authors: Ton Kuijpers, Daniëlle AWM van der Windt, Geert JMG van der Heijden, Jos WR Twisk, Yvonne Vergouwe and Lex M Bouter

    Citation: BMC Musculoskeletal Disorders 2006 7:97

    Content type: Research article

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  40. A wide range of outcomes have been assessed in trials of interventions for carpal tunnel syndrome (CTS), however there appears to be little consensus on what constitutes the most relevant outcomes. The purpose...

    Authors: Christina Jerosch-Herold, José C de Carvalho Leite and Fujian Song

    Citation: BMC Musculoskeletal Disorders 2006 7:96

    Content type: Research article

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  41. Metatarsalgia is related to repetitive high-pressure loading under the metatarsal head (MH) that causes pain. The high pressure under the MH can be reduced by adequately applying metatarsal pads (MPs). Plantar...

    Authors: Jiunn-Horng Kang, Min-Der Chen, Shih-Ching Chen and Wei-Li Hsi

    Citation: BMC Musculoskeletal Disorders 2006 7:95

    Content type: Research article

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  42. Progressive non-infectious anterior vertebral fusion is a unique spinal disorder with distinctive radiological features. Early radiographic findings consist of narrowing of the anterior aspect of the intervert...

    Authors: Ali Al Kaissi, Farid Ben Chehida, Maher Ben Ghachem, Franz Grill and Klaus Klaushofer

    Citation: BMC Musculoskeletal Disorders 2006 7:94

    Content type: Case report

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  43. Identification of locations with elevated plantar pressures is important in daily foot care for patients with rheumatoid arthritis, metatarsalgia and diabetes. The purpose of the present study was to evaluate ...

    Authors: Nick A Guldemond, Pieter Leffers, Fred HM Nieman, Antal P Sanders, Nicolaas C Schaper and Geert HIM Walenkamp

    Citation: BMC Musculoskeletal Disorders 2006 7:93

    Content type: Research article

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  44. Whole-body vibration (WBV) is a new type of exercise that has been increasingly tested for the ability to prevent bone fractures and osteoporosis in frail people. There are two currently marketed vibrating pla...

    Authors: Narcís Gusi, Armando Raimundo and Alejo Leal

    Citation: BMC Musculoskeletal Disorders 2006 7:92

    Content type: Research article

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  45. In complex regional pain syndrome type 1 (CRPS1) pro-inflammatory mediators and vascular changes play an important role in the sustained development and outcome of the disease. The aim of this study was to det...

    Authors: J George Groeneweg, Frank JPM Huygen, Claudia Heijmans-Antonissen, Sjoerd Niehof and Freek J Zijlstra

    Citation: BMC Musculoskeletal Disorders 2006 7:91

    Content type: Research article

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