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  1. Many people with musculoskeletal (MSK) disorders wait several months or years for Consultant Doctor appointments, despite often not requiring medical or surgical interventions. To allow earlier patient access ...

    Authors: Orna Fennelly, Catherine Blake, Oliver FitzGerald, Roisin Breen, Jennifer Ashton, Aisling Brennan, Aoife Caffrey, François Desmeules and Caitriona Cunningham
    Citation: BMC Musculoskeletal Disorders 2018 19:181
  2. Computed tomography (CT) analyses have reported that the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in Japan is 8.7–27.1%. However, these data were obtained using chest-abdominal CT, and no ...

    Authors: Akihiko Hiyama, Hiroyuki Katoh, Daisuke Sakai, Masato Sato, Masahiro Tanaka and Masahiko Watanabe
    Citation: BMC Musculoskeletal Disorders 2018 19:178
  3. Aseptic loosening and osteolysis are the most common indications after TKA for revision surgery. This meta-analysis which included high-quality randomized controlled trials (RCTs) aimed to analyze the effect o...

    Authors: Mingmin Shi, Lei Chen, Haobo Wu, Yangxin Wang, Wei Wang, Yujie Zhang and Shigui Yan
    Citation: BMC Musculoskeletal Disorders 2018 19:177
  4. The social impact of degenerative diseases is steadily increasing, because of the continued rise in the mean age of the active population. Articular cartilage lesions are generally associated with disability a...

    Authors: G. Cattaneo, A. De Caro, F. Napoli, D. Chiapale, P. Trada and A. Camera
    Citation: BMC Musculoskeletal Disorders 2018 19:176
  5. The anterior cruciate ligament (ACL) is responsible for braking forward movement of the tibia relative to the femur and for tibial rotation. After ACL injury, this braking performance deteriorates, inducing ab...

    Authors: Yuichi Nishikawa, Takanori Kokubun, Naohiko Kanemura, Tetsuya Takahashi, Masayasu Matsumoto, Hirofumi Maruyama and Kiyomi Takayanagi
    Citation: BMC Musculoskeletal Disorders 2018 19:175
  6. The relationships between radiographic hallux valgus (HV) and various physical functions independent of knee osteoarthritis (KOA) were examined among residents of a mountain village in Japan.

    Authors: Akinobu Nishimura, Naoya Ito, Shigeto Nakazora, Ko Kato, Toru Ogura and Akihiro Sudo
    Citation: BMC Musculoskeletal Disorders 2018 19:174
  7. Volumetric muscle loss (VML) injuries occur due to orthopaedic trauma or the surgical removal of skeletal muscle and result in debilitating long-term functional deficits. Current treatment strategies do not pr...

    Authors: Sarah M. Greising, Gordon L. Warren, W. Michael Southern, Anna S. Nichenko, Anita E. Qualls, Benjamin T. Corona and Jarrod A. Call
    Citation: BMC Musculoskeletal Disorders 2018 19:173
  8. This prospective study evaluates outcomes and reoperation rates for unicompartmental knee arthroplasty (UKA) from a single non-designer surgeon using relatively extended criteria of degenerative changes of gra...

    Authors: Jonathan R. B. Hutt, Avtar Sur, Hartej Sur, Aine Ringrose and Mark S. Rickman
    Citation: BMC Musculoskeletal Disorders 2018 19:172
  9. It has been suggested that the quantification of paravertebral muscle composition and morphology (e.g. size/shape/structure) with magnetic resonance imaging (MRI) has diagnostic, prognostic, and therapeutic po...

    Authors: James M. Elliott, Jon Cornwall, Ewan Kennedy, Rebecca Abbott and Rebecca J. Crawford
    Citation: BMC Musculoskeletal Disorders 2018 19:171
  10. Rockwood type IV acromioclavicular joint (ACJ) dislocation is a trauma usually needs surgical treatment. Paired EndoButton technique (PET) is used in treating such condition. However, the effect of using diffe...

    Authors: Jian Xu, Haifeng Liu, Wei Lu, Dingfu Li, Weimin Zhu, Kan Ouyang, Bing Wu, Liangquan Peng and Daping Wang
    Citation: BMC Musculoskeletal Disorders 2018 19:170
  11. Cartilage calcification (CC) is associated with osteoarthritis (OA) in weight-bearing joints, such as the hip and the knee. However, little is known about the impact of CC and degeneration on other weight-bear...

    Authors: Jan Hubert, Lukas Weiser, Sandra Hischke, Annemarie Uhlig, Tim Rolvien, Tobias Schmidt, Sebastian Karl Butscheidt, Klaus Püschel, Wolfgang Lehmann, Frank Timo Beil and Thelonius Hawellek
    Citation: BMC Musculoskeletal Disorders 2018 19:169
  12. Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could...

    Authors: Matthias Aurich, Gunther O. Hofmann, Florian Gras and Bernd Rolauffs
    Citation: BMC Musculoskeletal Disorders 2018 19:168
  13. Displaced transverse fractures of the body of the patella are usually associated with disruption of extensor mechanism and should be fixed surgically. The most common method is a tension band wiring (TBW) tech...

    Authors: Tien-Yu Yang, Tsan-Wen Huang, Po-Yao Chuang and Kuo-Chin Huang
    Citation: BMC Musculoskeletal Disorders 2018 19:167
  14. Nonspecific low back pain is characterized by a wide range of possible triggering and conserving factors, and initial screening needs to scope widely with multilevel addressment of possible factors contributin...

    Authors: Monica Unsgaard-Tøndel, Ingunn Gunnes Kregnes, Tom I. L. Nilsen, Gunn Hege Marchand and Torunn Askim
    Citation: BMC Musculoskeletal Disorders 2018 19:166
  15. Previous studies that have described the prevalence of patellofemoral pain (PFP) have been limited to samples of military personnel or sporting populations, and convincing data in the general Chinese populatio...

    Authors: Xingquan Xu, Chen Yao, Rui Wu, Wenjin Yan, Yao Yao, Kai Song, Qing Jiang and Dongquan Shi
    Citation: BMC Musculoskeletal Disorders 2018 19:165
  16. The progression of intervertebral disc (IVD) degeneration leads to rupture within IVD tissues. The location and appearance of areas of gaseous radiolucency in the IVD, known as vacuum phenomena (VPs), are cons...

    Authors: Koichiro Murata, Koji Akeda, Norihiko Takegami, Kevin Cheng, Koichi Masuda and Akihiro Sudo
    Citation: BMC Musculoskeletal Disorders 2018 19:164
  17. Angioleiomyoma is a very rare benign solitary soft tissue neoplasm originating from smooth muscle layer of blood vessels. The tumor is usually located in the subcutis or the superficial fasciae, but less often...

    Authors: Chenxi Cao, Zhengming Cao, Guangyu Liu, Songyang Liu, Yanqi Ye and Tiezheng Sun
    Citation: BMC Musculoskeletal Disorders 2018 19:163
  18. Outcomes of total knee replacement in cases of hemophilic patients are worse than in patients who undergo operations due to osteoarthritis. Previous publications have reported varying rates of complications in...

    Authors: Radovan Kubeš, Peter Salaj, Rastislav Hromádka, Josef Včelák, Aleš Antonín Kuběna, Monika Frydrychová, Štěpán Magerský, Michal Burian, Martin Ošťádal and Jan Vaculik
    Citation: BMC Musculoskeletal Disorders 2018 19:162
  19. A stress fracture (SF) is a highly debilitating injury commonly experienced in United States Army Basic Combat Training (BCT). Body fat (BF) may be associated with this injury but previous investigations (in a...

    Authors: Joseph J. Knapik, Marilyn A. Sharp and Scott J. Montain
    Citation: BMC Musculoskeletal Disorders 2018 19:161
  20. Dutasteride is a potent inhibitor of 5-alpha reductase enzymes that reduces concentrations of dihydrotestosterone to a greater extent than finasteride. Whether this has adverse implications for bone health is ...

    Authors: Tony Antoniou, Erin M. Macdonald, Zhan Yao, Tara Gomes, Mina Tadrous, Joanne M.-W. Ho, Muhammad M. Mamdani and David N. Juurlink
    Citation: BMC Musculoskeletal Disorders 2018 19:160
  21. As findings regarding predictors for good outcome after total joint arthroplasty are highly inconsistent, aim of this study was to investigate the influence of the psychosocial variables sense of coherence and...

    Authors: Marion Lindner, Olaf Nosseir, Anett Keller-Pliessnig, Per Teigelack, Martin Teufel and Sefik Tagay
    Citation: BMC Musculoskeletal Disorders 2018 19:159
  22. The purpose of our study was to evaluate safety, feasibility and clinical results of bone marrow mononuclear cell (BMC) implantation for early-stage osteonecrosis of the knee (OK) secondary to sickle cell dise...

    Authors: Gildasio Daltro, Bruno Adelmo Franco, Thiago Batista Faleiro, Davi Araujo Veiga Rosário, Paula Braga Daltro, Roberto Meyer and Vitor Fortuna
    Citation: BMC Musculoskeletal Disorders 2018 19:158
  23. Osteoarthritis (OA) is the most common joint disorder worldwide and one of the leading causes of disability in the elderly. We have investigated the novel sodium hyaluronate derivative chemically linked with d...

    Authors: Keiji Yoshioka, Tomochika Kisukeda, Ryoji Zuinen, Yosuke Yasuda and Kenji Miyamoto
    Citation: BMC Musculoskeletal Disorders 2018 19:157
  24. Based on the conservation of resource (COR) theory by Hobfoll, the aim of the present study was to test whether the relationships among relational demands, work meaning, and intention to leave vary as a functi...

    Authors: Daniela Converso, Sara Viotti, Ilaria Sottimano, Vincenza Cascio and Gloria Guidetti
    Citation: BMC Musculoskeletal Disorders 2018 19:156
  25. The Knee Injury and Osteoarthritis Outcome Score (KOOS) is a commonly used knee assessment and outcome tool in both clinical work and research. However, it has not been formally translated and validated in Fin...

    Authors: Juhani Multanen, Mikko Honkanen, Arja Häkkinen and Ilkka Kiviranta
    Citation: BMC Musculoskeletal Disorders 2018 19:155
  26. Since disc sequestration that mimics a tumor is rare and sometimes presents with an atypical appearance upon magnetic resonance imaging (MRI), it is often confused with other more common epidural and intradura...

    Authors: Jingyu Jia, Qiangqiang Wei, Tianlong Wu, Dingwen He and Xigao Cheng
    Citation: BMC Musculoskeletal Disorders 2018 19:154
  27. The physical and biochemical factors responsible for cervical disc degeneration, and resulting in various spinal disorders, remain unclear. This study aimed to evaluate the correlation between cervical spinal ...

    Authors: Kanichiro Wada, Toshihiro Tanaka, Gentaro Kumagai, Hitoshi Kudo, Toru Asari, Daisuke Chiba, Seiya Ota, Keita Kamei, On Takeda, Shigeyuki Nakaji and Yasuyuki Ishibashi
    Citation: BMC Musculoskeletal Disorders 2018 19:153
  28. Atypical lipomatous tumours (ALT) are common adipocytic tumours. Due to their large size and deep-seated location, wide resection might result in severe functional deficits. The question which margins should b...

    Authors: Jessica Rauh, Alexander Klein, Andrea Baur-Melnyk, Thomas Knösel, Lars Lindner, Falk Roeder, Volkmar Jansson and Hans Roland Dürr
    Citation: BMC Musculoskeletal Disorders 2018 19:152
  29. Pain and disability associated with degenerative lumbar spondylolisthesis (DLS) results in significant burden on both the patients’ quality of life and healthcare costs. Currently, there is controversy regardi...

    Authors: Qi Lai, Tian Gao, Xin Lv, Xuqiang Liu, Zongmiao Wan, Min Dai, Bin Zhang and Tao Nie
    Citation: BMC Musculoskeletal Disorders 2018 19:151
  30. Most studies demonstrated, that training on a virtual reality based arthroscopy simulator leads to an improvement of technical skills in orthopaedic surgery. However, how long and what kind of training is opti...

    Authors: Stefan Rahm, Karl Wieser, David E. Bauer, Felix WA Waibel, Dominik C. Meyer, Christian Gerber and Sandro F. Fucentese
    Citation: BMC Musculoskeletal Disorders 2018 19:150
  31. dGEMRIC (delayed Gadolinium Enhanced Magnetic Resonance Image of Cartilage) is a well-established technique for cartilage quality assessment in osteoarthritis at clinical field strengths. The method is robust,...

    Authors: Pernilla Peterson, Carl Johan Tiderius, Emma Olsson, Björn Lundin, Lars E. Olsson and Jonas Svensson
    Citation: BMC Musculoskeletal Disorders 2018 19:149
  32. Clinical evidence shows knee arthroscopy has little benefit for degenerative conditions and considerable variation in the incidence of knee arthroscopy in Australia has been identified. This study aimed to eva...

    Authors: H. Y. Chen, I. A. Harris, K. Sutherland and J-F. Levesque
    Citation: BMC Musculoskeletal Disorders 2018 19:148
  33. Lower limb strengthening, especially the quadriceps training, is of much necessity for patients with knee osteoarthritis (KOA). Previous studies suggest that strengthening of the hip muscles, especially the hip a...

    Authors: Yujie Xie, Chi Zhang, Wei Jiang, Juan Huang, Lili Xu, Guoyin Pang, Haiyan Tang, Ruyan Chen, Jihua Yu, Shengmin Guo, Fangyuan Xu and Jianxiong Wang
    Citation: BMC Musculoskeletal Disorders 2018 19:147
  34. The PACE Plus trial was a multi-center, double-blinded, superiority randomized controlled trial (RCT) conducted in patients from Dutch general practice to investigate the efficacy of paracetamol and NSAIDs in ...

    Authors: M. Schreijenberg, P. A. J. Luijsterburg, Y. D. M. Van Trier, D. Rizopoulos, M. A. Koopmanschap, L. Voogt, C. G. Maher and B. W. Koes
    Citation: BMC Musculoskeletal Disorders 2018 19:146
  35. Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by abnormal proliferation of skin and periosteal tissues of the extremities. It can be a rare hereditary disease (pachydermoperiostosis) or can b...

    Authors: Francesco Bozzao, Stella Bernardi, Franca Dore, Lorenzo Zandonà and Fabio Fischetti
    Citation: BMC Musculoskeletal Disorders 2018 19:145
  36. Knowledge on prevalence of osteoporosis stratifying for socioeconomic background is insufficient in Germany. Little is known in Europe about other diseases that go along with it although these aspects are impo...

    Authors: Marie-Therese Puth, Manuela Klaschik, Matthias Schmid, Klaus Weckbecker and Eva Münster
    Citation: BMC Musculoskeletal Disorders 2018 19:144
  37. Identification of poor prognostic factors for OVF is important but has not yet been clearly established. Despite paraspinal muscles could play an important role in the etiology of OVF, what influence time-depe...

    Authors: Marina Katsu, Tetsuro Ohba, Shigeto Ebata and Hirotaka Haro
    Citation: BMC Musculoskeletal Disorders 2018 19:143
  38. Patients with distal radius fractures (DRF) often have limited range-of-motion (ROM) in multiple planes of movement. No studies have comprehensively examined the impact of various ROM limitations on physical f...

    Authors: Zixian Yang, Peggy Poh Hoon Lim, Sing Hwee Teo, Huiwen Chen, Huaying Qiu and Yong Hao Pua
    Citation: BMC Musculoskeletal Disorders 2018 19:142
  39. Several studies looking into the association between insulin-like growth factor-1 (IGF-1) gene polymorphisms and osteoporosis predisposition have been conducted among Chinese population with conflicting outcom...

    Authors: Shu-tao Gao, Zheng-tao Lv, Chuan-kun Zhou, Chao Mao and Wei-bin Sheng
    Citation: BMC Musculoskeletal Disorders 2018 19:141
  40. A structured approach to perioperative patient management based on an enhanced recovery pathway protocol facilitates early recovery and reduces morbidity in high income countries. However, in low- and middle-i...

    Authors: U. Plenge, M. B. Nortje, L. C. Marais, J. D. Jordaan, R. Parker, N. van der Westhuizen, J. F. van der Merwe, J. Marais, W. V. September, G. L. Davies, T. Pretorius, C. Solomon, P. Ryan, A. M. Torborg, Z. Farina, R. Smit…
    Citation: BMC Musculoskeletal Disorders 2018 19:140
  41. The gene of pituitary homeobox 1 (PITX1) has been reported to be down-regulated in adolescent idiopathic scoliosis (AIS), of which the cause has not been well addressed. The abnormal DNA methylation was recent...

    Authors: Benlong Shi, Liang Xu, Saihu Mao, Leilei Xu, Zhen Liu, Xu Sun, Zezhang Zhu and Yong Qiu
    Citation: BMC Musculoskeletal Disorders 2018 19:138
  42. It was reported that Fas (rs1800682, rs2234767) and FasL (rs5030772, rs763110) gene polymorphism might be related to the risk of musculoskeletal degenerative diseases (MSDD), such as osteoarthritis (OA), inter...

    Authors: Donghua Huang, Jinrong Xiao, Xiangyu Deng, Kaige Ma, Hang Liang, Deyao Shi, Fashuai Wu and Zengwu Shao
    Citation: BMC Musculoskeletal Disorders 2018 19:137
  43. In lateral epicondylitis, even in the absence of apparent instability, subtle instability can be found under anesthesia. We wanted to ascertain the following: (1) how many elbows surgically treated with latera...

    Authors: Sang Ho Kwak, Seung-Jun Lee, Hee Seok Jeong, Min Uk Do and Kuen Tak Suh
    Citation: BMC Musculoskeletal Disorders 2018 19:136
  44. Magnetic Resonance Imaging (MRI) is commonly used to assess the health of the lumbar spine and supporting structures. Studies have suggested that fatty infiltration of the posterior lumbar muscles is important...

    Authors: David B. Berry, Jennifer Padwal, Seth Johnson, Callan L. Parra, Samuel R. Ward and Bahar Shahidi
    Citation: BMC Musculoskeletal Disorders 2018 19:135
  45. Several patient reported outcome measures (PROMs) are available for assessing the outcomes of ankle fracture but few have been compared for recommended measurement properties. This study compares the measureme...

    Authors: Andrew M. Garratt, Markus G. Naumann, Ulf Sigurdsen, Stein Erik Utvåg and Knut Stavem
    Citation: BMC Musculoskeletal Disorders 2018 19:134
  46. Painful shoulders pose a substantial socioeconomic burden accounting for 2.4% of all primary care consultations in the UK. There is a strong evidence to indicate that the majority of this shoulder pain can be ...

    Authors: Anthony W. Gilbert, Iva Hauptmannova and Anju Jaggi
    Citation: BMC Musculoskeletal Disorders 2018 19:133
  47. To increase the uptake of key clinical recommendations for non-surgical management of knee osteoarthritis (OA) and improve patient outcomes, we developed a new model of service delivery (PARTNER model) and an ...

    Authors: David J. Hunter, Rana S. Hinman, Jocelyn L. Bowden, Thorlene Egerton, Andrew M. Briggs, Stephen J. Bunker, Jessica Kasza, Andrew B. Forbes, Simon D. French, Marie Pirotta, Deborah J. Schofield, Nicholas A. Zwar and Kim L. Bennell
    Citation: BMC Musculoskeletal Disorders 2018 19:132

    The Correction to this article has been published in BMC Musculoskeletal Disorders 2018 19:443

  48. Distal radial fractures are one of the most common orthopaedic cases that present to the A&E department. Surgical intervention is warranted in displaced intraarticular fractures and fractures with more than th...

    Authors: V. D. Varghese, Peter Smitham, Stuart Howell, Suzanne Edwards and Mark Rickman
    Citation: BMC Musculoskeletal Disorders 2018 19:131
  49. It was indicated that inhibition of PPARγ probably represents a novel therapy for steroid-related osteonecrosis. In this study, we investigated the preventive effects of PPARγ inhibition on steroid-related ost...

    Authors: Na Yuan, Jia Li, Meng Li, Wenchen Ji, Zhaogang Ge, Lihong Fan and Kunzheng Wang
    Citation: BMC Musculoskeletal Disorders 2018 19:129

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