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  1. Low bone mineral density (BMD) and subsequent fractures are a major public health problem in postmenopausal women. The purpose of this study was to use the aggregate data meta-analytic approach to examine the ...

    Authors: George A Kelley, Kristi S Kelley and Wendy M Kohrt

    Citation: BMC Musculoskeletal Disorders 2012 13:177

    Content type: Research article

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  2. Children with growth retardation or short stature generally present with lower strength than children of the same chronological age. The aim of the study was to establish if strength was dependent on variables...

    Authors: Jean-Yves Hogrel, Valérie Decostre, Corinne Alberti, Aurélie Canal, Gwenn Ollivier, Emilie Josserand, Ilham Taouil and Dominique Simon

    Citation: BMC Musculoskeletal Disorders 2012 13:176

    Content type: Research article

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  3. Tissue adhesives are useful means for various medical procedures. Since varying requirements cause that a single adhesive cannot meet all needs, bond strength testing remains one of the key applications used t...

    Authors: Tilo Dehne, Rolf Zehbe, Jan Philipp Krüger, Aneliya Petrova, Rafael Valbuena, Michael Sittinger, Helmut Schubert and Jochen Ringe

    Citation: BMC Musculoskeletal Disorders 2012 13:175

    Content type: Technical advance

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  4. Long term serum urate (SU) lowering to a target of <0.36 mmol/l (6 mg/dl) is recommended for effective gout management. However, many studies have reported low achievement of SU targets. The aim of this cross-...

    Authors: Nicola Dalbeth, Meaghan E House, Anne Horne, Keith J Petrie, Fiona M McQueen and William J Taylor

    Citation: BMC Musculoskeletal Disorders 2012 13:174

    Content type: Research article

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  5. Several risk factors are associated to hip fractures. It seems that different hip fracture types have different etiologies. In this study, we evaluated the lifestyle-related risk factors for cervical and troch...

    Authors: Mikko Määttä, Erkki Terho, Heikki Jokinen, Pasi Pulkkinen, Juha Korpelainen, Jorma Heikkinen, Sirkka Keinänen-Kiukaanniemi, Timo Jämsä and Raija Korpelainen

    Citation: BMC Musculoskeletal Disorders 2012 13:173

    Content type: Research article

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  6. Titanium (TTN) cages have a higher modulus of elasticity when compared with polyetheretherketone (PEEK) cages. This suggests that TTN-cages could show more frequent cage subsidence after anterior cervical disc...

    Authors: Mario Cabraja, Soner Oezdemir, Daniel Koeppen and Stefan Kroppenstedt

    Citation: BMC Musculoskeletal Disorders 2012 13:172

    Content type: Research article

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  7. Femoral neck fractures with a vertical orientation have been associated with an increased risk for failure as they are both axial and rotational unstable and experience increased shear forces compared to the c...

    Authors: Anders Enocson and Lasse J Lapidus

    Citation: BMC Musculoskeletal Disorders 2012 13:171

    Content type: Research article

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  8. The objective of this study was to evaluate the impact of rheumatoid arthritis (RA) on patients’ sexuality and identify disease and other factors such as fatigue that most influence sexual relationships.

    Authors: Gisela Kobelt, Brigitte Texier-Richard, Sylvain Mimoun, Anne-Sophie Woronoff, David-Romain Bertholon, Aleth Perdriger, Yves Maugars and Bernard Combe

    Citation: BMC Musculoskeletal Disorders 2012 13:170

    Content type: Research article

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  9. Physiotherapy for people with low back pain frequently includes assessment and modification of lumbo-pelvic movement. Interventions commonly aim to restore normal movement and thereby reduce pain and improve a...

    Authors: Robert A Laird, Peter Kent and Jennifer L Keating

    Citation: BMC Musculoskeletal Disorders 2012 13:169

    Content type: Research article

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  10. Pain and radiographic changes are common in persons with osteoarthritis, but their relative contributions to quality of life are unknown.

    Authors: Laura L Laslett, Stephen J Quinn, Tania M Winzenberg, Kristy Sanderson, Flavia Cicuttini and Graeme Jones

    Citation: BMC Musculoskeletal Disorders 2012 13:168

    Content type: Research article

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  11. Proximal humerus fracture is the third most common fracture type after hip and distal radius fracture in elderly patients. A comprehensive study by Palvanen et al. demonstrated an increase in the annual fracture ...

    Authors: Antti P Launonen, Vesa Lepola, Tapio Flinkkilä, Niko Strandberg, Johanna Ojanperä, Pekka Rissanen, Antti Malmivaara, Ville M Mattila, Petra Elo, Timo Viljakka and Minna Laitinen

    Citation: BMC Musculoskeletal Disorders 2012 13:167

    Content type: Study protocol

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  12. There is continuing uncertainty in back pain research as to which treatment is best suited to patients with non-specific chronic low back pain (CLBP). In this study, Gestalt therapy and the shock trauma method...

    Authors: Hanne Ellegaard and Birthe D Pedersen

    Citation: BMC Musculoskeletal Disorders 2012 13:166

    Content type: Research article

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  13. Psychiatric comorbidity is common in back pain patients undergoing disc surgery and increases economic costs in many areas of health. The objective of this study was to analyse psychiatric comorbidity as predi...

    Authors: Alexander Konnopka, Margrit Löbner, Melanie Luppa, Dirk Heider, Sven Heinrich, Steffi Riedel-Heller, Hans Jörg Meisel, Lutz Günther, Jürgen Meixensberger and Hans-Helmut König

    Citation: BMC Musculoskeletal Disorders 2012 13:165

    Content type: Research article

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  14. Craniocervical arterial dissection is a major cause of ischaemic stroke in young adults. The pathogenesis is not fully understood but is thought to be related to a combination of an intrinsic weakness in the a...

    Authors: Lucy C Thomas, Darren A Rivett, John R Attia and Christopher R Levi

    Citation: BMC Musculoskeletal Disorders 2012 13:164

    Content type: Study protocol

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  15. Vertebral fractures, the most common type of osteoporotic fractures, are associated with increased risk of subsequent fracture, morbidity, and mortality. The aim of this study was to examine the contribution o...

    Authors: Svanhild Waterloo, Tuan Nguyen, Luai A Ahmed, Jacqueline R Center, Bente Morseth, Nguyen D Nguyen, John A Eisman, Anne J Søgaard and Nina Emaus

    Citation: BMC Musculoskeletal Disorders 2012 13:163

    Content type: Research article

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  16. Recent clinical recommendations still propose active exercises (AE) for CNSLBP. However, acceptance of exercises by patients may be limited by pain-related manifestations. Current evidences suggest that manual...

    Authors: Pierre Balthazard, Pierre de Goumoens, Gilles Rivier, Philippe Demeulenaere, Pierluigi Ballabeni and Olivier Dériaz

    Citation: BMC Musculoskeletal Disorders 2012 13:162

    Content type: Research article

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  17. The complications of reversed total shoulder arthroplasty (RTSA) requiring an additional intervention, their treatment options and outcome are poorly known. It was therefore the purpose of this retrospective s...

    Authors: Mazda Farshad, Marion Grögli, Sabrina Catanzaro and Christian Gerber

    Citation: BMC Musculoskeletal Disorders 2012 13:160

    Content type: Research article

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  18. Most modern spinal implants contain titanium and remain in the patient’s body permanently. Local and systemic effects such as tissue necrosis, osteolysis and malignant cell transformation caused by implants ha...

    Authors: Ingmar Ipach, Ralf Schäfer, Falk Mittag, Carmen Leichtle, Petra Wolf and Torsten Kluba

    Citation: BMC Musculoskeletal Disorders 2012 13:159

    Content type: Research article

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  19. Patients with rheumatoid arthritis (RA) are known to be at increased risk of infection, particularly if they are taking drugs with immunomodulatory effects. There is a need for more information on the risk of ...

    Authors: William A Blumentals, Anna Arreglado, Pavel Napalkov and Stephen Toovey

    Citation: BMC Musculoskeletal Disorders 2012 13:158

    Content type: Research article

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  20. Currently, no validated instruments are available to measure the health status of Bangladeshi patients with fibromyalgia (FM). The aims of this study were to cross-culturally adapt the modified Fibromyalgia Im...

    Authors: Mohammed A Muquith, Md Nazrul Islam, Syed A Haq, Peter M ten Klooster, Johannes J Rasker and Muhammad B Yunus

    Citation: BMC Musculoskeletal Disorders 2012 13:157

    Content type: Research article

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  21. Sick-listed employees with low back pain had similar return to work (RTW) rates at one-year follow-up in a randomized trial comparing two interventions, but the effects were modified by specific workplace rela...

    Authors: Chris Jensen, Ole Kudsk Jensen and Claus Vinther Nielsen

    Citation: BMC Musculoskeletal Disorders 2012 13:156

    Content type: Research article

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  22. This cross validation study examined the reliability of the Multidimensional Pain Inventory (MPI) and the stability of the Multidimensional Pain Inventory Classification System of the empirically derived subgr...

    Authors: Martin L Verra, Felix Angst, J Bart Staal, Roberto Brioschi, Susanne Lehmann, André Aeschlimann and Rob A de Bie

    Citation: BMC Musculoskeletal Disorders 2012 13:155

    Content type: Research article

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  23. Osteoclasts and osteoblasts regulate bone resorption and formation to allow bone remodeling and homeostasis. The balance between bone resorption and formation is disturbed by abnormal recruitment of osteoclast...

    Authors: Ruofan Ma, Jie Xu, Bin Dong, Max Daniel Kauther, Marcus Jäger and Christian Wedemeyer

    Citation: BMC Musculoskeletal Disorders 2012 13:154

    Content type: Research article

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  24. The aim of this study was to document the development of bilateral knee osteoarthritis over a 12 year period using a middle-aged population-based cohort with knee pain at inclusion.

    Authors: Andrew J Metcalfe, Maria LE Andersson, Rhian Goodfellow and Carina A Thorstensson

    Citation: BMC Musculoskeletal Disorders 2012 13:153

    Content type: Research article

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  25. Preventive interventions improve healthy behaviours and they also increase knowledge regarding back care in children and adolescents, but studies exhibit great variability in their contents, duration and numbe...

    Authors: Inmaculada Calvo-Muñoz, Antonia Gómez-Conesa and Julio Sánchez-Meca

    Citation: BMC Musculoskeletal Disorders 2012 13:152

    Content type: Research article

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  26. The aim of this randomized clinical trial was to assess the effect of early orthodontic treatment for unilateral posterior cross bite in the late deciduous and early mixed dentition using orthopedic parameters.

    Authors: Carsten Lippold, Tatjana Moiseenko, Burkhard Drerup, Markus Schilgen, András Végh and Gholamreza Danesh

    Citation: BMC Musculoskeletal Disorders 2012 13:151

    Content type: Research article

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  27. There is accumulating evidence for an increased cardiovascular burden in inflammatory arthritis, but the true magnitude of this cardiovascular burden is still debated. We sought to determine the prevalence rat...

    Authors: Markus MJ Nielen, Alper M van Sijl, Mike JL Peters, Robert A Verheij, François G Schellevis and Michael T Nurmohamed

    Citation: BMC Musculoskeletal Disorders 2012 13:150

    Content type: Research article

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  28. Approximately 20% of patients report persistent and disabling pain following total knee arthroplasty (TKA) despite an apparently normally functioning prosthesis. One potential risk factor for unexplained persi...

    Authors: Daniel L Riddle, Francis J Keefe, Dennis Ang, Khaled J, Levent Dumenci, Mark P Jensen, Matthew J Bair, Shelby D Reed and Kurt Kroenke

    Citation: BMC Musculoskeletal Disorders 2012 13:149

    Content type: Study protocol

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  29. Foot deformities and related problems of the forefoot are very common in patients with rheumatoid arthritis. The laxity of the medial cuneometatarsal joint and its synovitis are important factors in the develo...

    Authors: Stanislav Popelka, Rastislav Hromádka, Pavel Vavřík, Vladislav Barták, Stanislav Popelka Jr and Antonín Sosna

    Citation: BMC Musculoskeletal Disorders 2012 13:148

    Content type: Research article

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  30. The clinical results of removal of metal implants after fracture healing are unknown and the question whether to remove or to leave them in is part of discussion worldwide. We present the design of a prospecti...

    Authors: Dagmar I Vos, Michael HJ Verhofstad, Beate Hanson, Yolanda van der Graaf and Chris van der Werken

    Citation: BMC Musculoskeletal Disorders 2012 13:147

    Content type: Study protocol

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  31. Sympathetic nervous activity contributes to the maintenance of muscle oxygenation. However, patients with chronic pain may suffer from autonomic dysfunction. Furthermore, insufficient muscle oxygenation is obs...

    Authors: Yukiko Shiro, Young-Chang P Arai, Takako Matsubara, Shunsuke Isogai and Takahiro Ushida

    Citation: BMC Musculoskeletal Disorders 2012 13:146

    Content type: Research article

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  32. Prolonged sitting has been associated with musculoskeletal dysfunction. For desk workers, workstation modifications frequently address the work surface and chair. Chairs which can prevent abnormal strain of th...

    Authors: Sjan-Mari van Niekerk, Quinette Abigail Louw and Susan Hillier

    Citation: BMC Musculoskeletal Disorders 2012 13:145

    Content type: Research article

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  33. Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the articular cartilage due to environmental, mechanical and genetic components. The genetics of OA is complex and is not complet...

    Authors: Silvia Díaz-Prado, Claudia Cicione, Emma Muiños-López, Tamara Hermida-Gómez, Natividad Oreiro, Carlos Fernández-López and Francisco J Blanco

    Citation: BMC Musculoskeletal Disorders 2012 13:144

    Content type: Research article

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  34. Various risk of mortality due to hip fracture has been reported by different studies. There is scarce controlled study on hip fracture mortality from developing countries and no data from Middle East region. T...

    Authors: Majid Valizadeh, Saeideh Mazloomzadeh, Somayeh Golmohammadi and Bagher Larijani

    Citation: BMC Musculoskeletal Disorders 2012 13:143

    Content type: Research article

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  35. To investigate the efficacy of the sole core decompression surgery for the treatment of steroid-induced femoral head osteonecrosis.

    Authors: Wei Wang, Liying Liu, Xiaoqian Dang, Shuqiang Ma, Mingyu Zhang and Kunzheng Wang

    Citation: BMC Musculoskeletal Disorders 2012 13:142

    Content type: Research article

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  36. A minimal invasive approach for elective hip surgery has been implemented in our institution in the past. It is widely hypothesized that implanting artificial hips in a minimal invasive fashion decreases surgi...

    Authors: Felix Renken, Svenja Renken, Andreas Paech, Michael Wenzl, Andreas Unger and Arndt P Schulz

    Citation: BMC Musculoskeletal Disorders 2012 13:141

    Content type: Research article

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  37. The treatment of rotator cuff tears is still challenging. Tendon tissue engineering (TTE) might be an alternative in future. Tenocytes seem to be the most suitable cell type as they are easy to obtain and no d...

    Authors: Markus U Wagenhäuser, Matthias F Pietschmann, Birte Sievers, Denitsa Docheva, Matthias Schieker, Volkmar Jansson and Peter E Müller

    Citation: BMC Musculoskeletal Disorders 2012 13:140

    Content type: Research article

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  38. The aim was to compare the return-to-sports-time (RTST) following stress fractures on the basis of site and severity of injury. This retrospective study was set up at a single institution. Diagnosis was confir...

    Authors: Oliver Dobrindt, Birgit Hoffmeyer, Juri Ruf, Max Seidensticker, Ingo G Steffen, Frank Fischbach, Alina Zarva, Gero Wieners, Gerhard Ulrich, Christoph H Lohmann and Holger Amthauer

    Citation: BMC Musculoskeletal Disorders 2012 13:139

    Content type: Research article

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  39. Muscle injuries are one of the commonest injuries affecting athletes. It often leads to significant pain and disability causing loss of training and competition time. With current treatment, the duration to re...

    Authors: Mohamad Shariff A Hamid, Mohamed Razif Mohamed Ali, Ashril Yusof and John George

    Citation: BMC Musculoskeletal Disorders 2012 13:138

    Content type: Study protocol

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  40. Pain conditions of the musculoskeletal system are very common and have tremendous socioeconomic impact. Despite its high prevalence, musculoskeletal pain remains poorly understood and predominantly non-specifi...

    Authors: Andreas Gerhardt, Mechthild Hartmann, Jonas Tesarz, Susanne Janke, Sabine Leisner, Günter Seidler and Wolfgang Eich

    Citation: BMC Musculoskeletal Disorders 2012 13:136

    Content type: Study protocol

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  41. Few studies have investigated the use of a 3-dimensional gyroscope for measuring the range of motion (ROM) in the impaired shoulder. Reproducibility of digital inclinometer and visual estimation is poor. This ...

    Authors: Ludo I F Penning, Nick A Guldemond, Rob A de Bie and Geert H I M Walenkamp

    Citation: BMC Musculoskeletal Disorders 2012 13:135

    Content type: Research article

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  42. Various treatments for unicameral bone cyst have been proposed. Recent concern focuses on the effectiveness of closed methods. This study evaluated the effectiveness of demineralized bone matrix as a graft mat...

    Authors: Hwan Seong Cho, Sung Hwa Seo, So Hyun Park, Jong Hoon Park, Duk Seop Shin and Il Hyung Park

    Citation: BMC Musculoskeletal Disorders 2012 13:134

    Content type: Research article

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  43. There are few data concerning the impact of inflammatory polyarthritis (IP) on quantitative heel ultrasound (QUS) measurements. The aims of this analysis were i) to determine the influence of IP on QUS measure...

    Authors: Stephen R Pye, Tarnya Marshall, Karl Gaffney, Robert Luben, Kay-Tee Khaw, Alan J Silman, Deborah PM Symmons and Terence W O’Neill

    Citation: BMC Musculoskeletal Disorders 2012 13:133

    Content type: Research article

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  44. In adolescents, loss of bone mineral mass usually occurs during phases of reduced physical activity (PA), such as when an injured extremity spends several weeks in a cast. We recorded the PA of adolescents wit...

    Authors: Dimitri Ceroni, Xavier Martin, Léopold Lamah, Cécile Delhumeau, Nathalie Farpour-Lambert, Geraldo De Coulon and Victor Dubois Ferrière

    Citation: BMC Musculoskeletal Disorders 2012 13:131

    Content type: Research article

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  45. Kashin-Beck Disease (KBD) is an endemic osteochondropathy. Mycotoxins are believed to play an important role in the pathogenesis of KBD. Because the molecular mechanism of mycotoxin-induced cartilage lesions r...

    Authors: Feng Zhang, Xiong Guo, Weizhuo Wang, Shixun Wu, Weijuan Ma and Hua Yan

    Citation: BMC Musculoskeletal Disorders 2012 13:130

    Content type: Research article

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  46. Knee osteoarthritis (OA) is a prevalent chronic musculoskeletal condition with no cure. Pain is the primary symptom and results from a complex interaction between structural changes, physical impairments and p...

    Authors: Kim L Bennell, Yasmin Ahamed, Christina Bryant, Gwendolen Jull, Michael A Hunt, Justin Kenardy, Andrew Forbes, Anthony Harris, Michael Nicholas, Ben Metcalf, Thorlene Egerton and Francis J Keefe

    Citation: BMC Musculoskeletal Disorders 2012 13:129

    Content type: Study protocol

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  47. To determine the prevalence of vertebral fractures (VFs) after 5 years of disease activity score (DAS)-steered treatment in patients with early rheumatoid arthritis (RA) and to investigate the association of V...

    Authors: Linda Dirven, M van den Broek, J H L M van Groenendael, W M de Beus, P J S M Kerstens, T W J Huizinga, C F Allaart and W F Lems

    Citation: BMC Musculoskeletal Disorders 2012 13:125

    Content type: Research article

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