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Orthopedics and biomechanics

This section concerns all aspects of orthopedic treatments for musculoskeletal disorders including but not limited to: orthopedic surgery and related biomechanics, non-surgical orthoses, and tissue engineering.

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  1. Several bone implants are applied in clinical practice, but none meets the requirements of an ideal implant. Platelet-rich plasma (PRP) is an easy and inexpensive way to obtain growth factors in physiologic pr...

    Authors: Alice Roffi, Giuseppe Filardo, Elizaveta Kon and Maurilio Marcacci

    Citation: BMC Musculoskeletal Disorders 2013 14:330

    Content type: Research article

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  2. Self-reported knee joint instability compromises function in individuals with medial knee osteoarthritis and may be related to impaired joint mechanics. The purpose of this study was to evaluate the relationsh...

    Authors: Mark W Creaby, Tim V Wrigley, Boon-Whatt Lim, Rana S Hinman, Adam L Bryant and Kim L Bennell

    Citation: BMC Musculoskeletal Disorders 2013 14:326

    Content type: Research article

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  3. Loss of meniscal tissue is correlated with early osteoarthritis but few data exist regarding detailed biomechanical properties (e.g. viscoelastic behavior) of menisci in different species commonly used as anim...

    Authors: Gunther H Sandmann, Christopher Adamczyk, Eduardo Grande Garcia, Stefan Doebele, Andreas Buettner, Stefan Milz, Andreas B Imhoff, Stefan Vogt, Rainer Burgkart and Thomas Tischer

    Citation: BMC Musculoskeletal Disorders 2013 14:324

    Content type: Research article

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  4. There are few Scandinavian studies on the effect of computer assisted orthopedic surgery (CAOS) in total knee arthroplasty (TKA), compared to conventional technique (CON), and there is little information on ef...

    Authors: Gro Sævik Dyrhovden, Øystein Gøthesen, Stein Håkon Låstad Lygre, Anne Marie Fenstad, Tor Egil Sørås, Svein Halvorsen, Truls Jellestad and Ove Furnes

    Citation: BMC Musculoskeletal Disorders 2013 14:321

    Content type: Research article

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  5. Giant cell tumors (GCT) around the knee are common and pose a special problem of reconstruction after tumor excision, especially for grade III GCT. We questioned whether en bloc resection and reconstruction wi...

    Authors: SongFeng Xu, XiuChun Yu, Ming Xu and ZhiHou Fu

    Citation: BMC Musculoskeletal Disorders 2013 14:319

    Content type: Research article

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  6. Development of a pre-vascularized tissue-engineered construct with intrinsic vascular system for cell growth and tissue formation still faces many difficulties due to the complexity of the vascular network of ...

    Authors: Pei Yang, Xin Huang, Jacson Shen, Chunsheng Wang, Xiaoqian Dang, Henry Mankin, Zhenfeng Duan and Kunzheng Wang

    Citation: BMC Musculoskeletal Disorders 2013 14:318

    Content type: Research article

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  7. Conversion of a knee arthrodesis to a Total Knee Arthroplasty is an uncommon procedure. Revision Total Knee Arthroplasty in this setting presents the surgeon with a number of challenges including the managemen...

    Authors: Alfonso Manzotti, Simone Aldè, Chris Pullen, Pietro Cerveri and Norberto Confalonieri

    Citation: BMC Musculoskeletal Disorders 2013 14:317

    Content type: Case report

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  8. Standard plate fixation can be used to treat intraarticular olecranon fractures with satisfactory functional recovery, but its use is accompanied by implant related complications. This retrospective study repo...

    Authors: Wei Chen, Qi Zhang, Zhiyong Hou and Yingze Zhang

    Citation: BMC Musculoskeletal Disorders 2013 14:308

    Content type: Research article

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  9. While arthrodesis is the standard treatment of a severely arthritic ankle joint, total ankle arthroplasty has become a popular alternative. This review provides clinical outcomes and complications of both inte...

    Authors: Jacqueline van Heiningen, Thea PM Vliet Vlieland and Huub JL van der Heide

    Citation: BMC Musculoskeletal Disorders 2013 14:306

    Content type: Research article

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  10. Studies dealing with acute osseous Bankart lesions and corresponding treatment strategies are rare. The purpose of this study is to analyze the results after applying our treatment algorithm for acute glenoid ...

    Authors: Ulrich J A Spiegl, Christian Ryf, Pierre Hepp and Paavo Rillmann

    Citation: BMC Musculoskeletal Disorders 2013 14:305

    Content type: Research article

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  11. Femoral fracture rates of up to 30% have been reported following lengthening procedures using fixators. “Lengthening then rodding” uses one or two titanium elastic nails (TENs) for prophylactic intramedullary ...

    Authors: Frank Schiedel, Ulrich Elsner, Georg Gosheger, Björn Vogt and Robert Rödl

    Citation: BMC Musculoskeletal Disorders 2013 14:302

    Content type: Research article

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  12. Optimal postoperative pain management is important to ensure patient comfort and early mobilization.

    Authors: Narinder Rawal, Eugene Viscusi, Paul M Peloso, Harold S Minkowitz, Liang Chen, Sandhya Shah, Anish Mehta, Denesh K Chitkara, Sean P Curtis and Dimitris A Papanicolaou

    Citation: BMC Musculoskeletal Disorders 2013 14:300

    Content type: Research article

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  13. It is well established that males have lower fracture risk in comparison with females, which suggests a higher bone resistance in men. The aim of our study was to find out if in older patients with hip fragili...

    Authors: Ana C Vale, Inês P Aleixo, Miguel Lúcio, André Saraiva, Joana Caetano-Lopes, Ana Rodrigues, Pedro M Amaral, Luís G Rosa, Jacinto Monteiro, João E Fonseca, Maria F Vaz and Helena Canhão

    Citation: BMC Musculoskeletal Disorders 2013 14:295

    Content type: Research article

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  14. Our purpose was to analyze and compare the use of direct health resources and costs generated in the treatment of Dupuytren's contracture using two different techniques: subtotal fasciectomy and infiltration w...

    Authors: Rafael Sanjuan Cerveró, Nuria Franco Ferrando and Jaime Poquet Jornet

    Citation: BMC Musculoskeletal Disorders 2013 14:293

    Content type: Research article

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  15. Utilization of total knee arthroplasty is increasing rapidly. A substantial number of total knee arthroplasty recipients have persistent pain after surgery. Our objective was to design a randomized controlled ...

    Authors: Elena Losina, Jamie E Collins, Meghan E Daigle, Laurel A Donnell-Fink, Julian JZ Prokopetz, Doris Strnad, Vladislav Lerner, Benjamin N Rome, Roya Ghazinouri, Debra J Skoniecki, Jeffrey N Katz and John Wright

    Citation: BMC Musculoskeletal Disorders 2013 14:290

    Content type: Study protocol

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  16. Articular cartilage is a solid-fluid biphasic material covering the bony ends of articulating joints. Hydration of articular cartilage is important to joint lubrication and weight-wearing. The aims of this stu...

    Authors: Qing Wang, Yi-Yi Yang, Hai-Jun Niu, Wen-Jing Zhang, Qian-Jin Feng and Wu-Fan Chen

    Citation: BMC Musculoskeletal Disorders 2013 14:289

    Content type: Research article

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  17. The Fracture Risk Assessment (FRAX) tool has been developed by the World Health Organization (WHO) to calculate 10-year probability hip fracture (HP) or major osteoporotic fracture (MOF). The objective of this...

    Authors: Mai B Aker, Adham S Abu Taha, Sa’ed H Zyoud, Ansam F Sawalha, Samah W Al-Jabi and Waleed M Sweileh

    Citation: BMC Musculoskeletal Disorders 2013 14:284

    Content type: Research article

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  18. For anterior lumbar interbody fusion (ALIF), stand-alone cages can be supplemented with vertebral plate, locking screws, or threaded cylinder to avoid the use of posterior fixation. Intuitively, the plate, scr...

    Authors: Shih-Hao Chen, Ming-Chieh Chiang, Jin-Fu Lin, Shang-Chih Lin and Ching-Hua Hung

    Citation: BMC Musculoskeletal Disorders 2013 14:281

    Content type: Research article

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  19. In anterior cervical spine surgery a retractor is obligatory to approach the spine. Previous studies showed an increase of endotracheal tube cuff pressure after placement of a retractor. It is known that high ...

    Authors: Mark P Arts, Thijs C D Rettig, Jessica de Vries, Jasper F C Wolfs and Bas A in’t Veld

    Citation: BMC Musculoskeletal Disorders 2013 14:280

    Content type: Study protocol

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  20. Several organizations seek to address the growing burden of arthritis in developing countries by providing total joint replacements (TJR) to patients with advanced arthritis who otherwise would not have access...

    Authors: Kyle E Dempsey, Roya Ghazinouri, Desiree Diez, Luis Alcantara, Carolyn Beagan, Barbara Aggouras, Monica Hoagland, Thomas S Thornhill and Jeffrey N Katz

    Citation: BMC Musculoskeletal Disorders 2013 14:275

    Content type: Research article

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  21. Spinal systems that are currently available for correction of spinal deformities or degeneration such as lumbar spondylolisthesis or degenerative disc disease use components manufactured from stainless steel o...

    Authors: Dennis Kok, Paul John Firkins, Frits H Wapstra and Albert G Veldhuizen

    Citation: BMC Musculoskeletal Disorders 2013 14:269

    Content type: Research article

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  22. Severe knee pain associated with osteoarthritis (OA) is one of the most common and troublesome symptoms in the elderly. Recently, local bone denervation by MR-guided focused ultrasound (MRgFUS) has been demons...

    Authors: Masashi Izumi, Masahiko Ikeuchi, Motohiro Kawasaki, Takahiro Ushida, Kazuo Morio, Hirofumi Namba, Thomas Graven-Nielsen, Yasuhiro Ogawa and Toshikazu Tani

    Citation: BMC Musculoskeletal Disorders 2013 14:267

    Content type: Technical advance

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  23. Ankle osteoarthritis commonly involves sagittal malalignment with anterior translation of the talus relative to the tibia. Total ankle arthroplasty has become an increasingly popular treatment for patients wit...

    Authors: Keun-Bae Lee, Myung-Sun Kim, Kyung-Soon Park, Kyu-Jin Cho and Andri Primadhi

    Citation: BMC Musculoskeletal Disorders 2013 14:260

    Content type: Research article

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  24. Acute compartment syndrome (CS) of the paravertebral muscles without external trauma is rarely reported in literature. Not all of clinical symptoms for CS are applicable to the paravertebral region.

    Authors: Georg Mattiassich, Lorenz Larcher, Markus Leitinger, Eugen Trinka, Gottfried Wechselberger and Heinrich Schubert

    Citation: BMC Musculoskeletal Disorders 2013 14:259

    Content type: Case report

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  25. Anterior bone grafts are used as struts to reconstruct the anterior column of the spine in kyphosis or following injury. An incomplete fusion can lead to later correction losses and compromise further healing....

    Authors: Antonius Pizanis, Jörg H Holstein, Felix Vossen, Markus Burkhardt and Tim Pohlemann

    Citation: BMC Musculoskeletal Disorders 2013 14:254

    Content type: Research article

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  26. Despite the emerging use of treadmills integrated with pressure platforms as outcome tools in both clinical and research settings, published evidence regarding the measurement properties of these new systems i...

    Authors: Lloyd F Reed, Stephen R Urry and Scott C Wearing

    Citation: BMC Musculoskeletal Disorders 2013 14:249

    Content type: Research article

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  27. It seems appropriate to assume, that for a full and strong global shoulder function a normally innervated and active deltoid muscle is indispensable. We set out to analyse the size and shape of the deltoid mus...

    Authors: Dominik C Meyer, Stefan Rahm, Mazda Farshad, Georg Lajtai and Karl Wieser

    Citation: BMC Musculoskeletal Disorders 2013 14:247

    Content type: Research article

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  28. Current tendon repair techniques do not provide sufficient tensile strength at the repair site, and thus early active motion rehabilitation after tendon repair is discouraged. To enhance the post-operative ten...

    Authors: Jian-Zhong Hu, Yong-Chun Zhou, Li-Hua Huang and Hong-Bin Lu

    Citation: BMC Musculoskeletal Disorders 2013 14:246

    Content type: Research article

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  29. In instrumented posterolateral fusion reduction of a spondylolisthesis is appealing on theoretical grounds since this may lead to indirect decompression of the entrapped nerve roots. However, there is no conse...

    Authors: HS Femke Hagenmaier, Diyar Delawi, Nico Verschoor, F Cumhur Oner and Job LC van Susante

    Citation: BMC Musculoskeletal Disorders 2013 14:245

    Content type: Research article

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  30. Anterior cervical discectomy with interbody fusion cages is considered the standard surgical procedure in patients with cervical disc herniation. However, PEEK or metal cages have some undesirable imaging char...

    Authors: Mark P Arts, Jasper FC Wolfs and Terry P Corbin

    Citation: BMC Musculoskeletal Disorders 2013 14:244

    Content type: Study protocol

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  31. To inform the clinical management of patients with suspected carpal tunnel syndrome (CTS) and case definition for CTS in epidemiological research, we explored the relation of symptoms and signs to sensory nerv...

    Authors: Georgia Ntani, Keith T Palmer, Cathy Linaker, E Clare Harris, Richard Van der Star, Cyrus Cooper and David Coggon

    Citation: BMC Musculoskeletal Disorders 2013 14:242

    Content type: Research article

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  32. Up to one third of BKP treated cases shows no appreciable height restoration due to loss of both restored height and kyphotic realignment after balloon deflation. This shortcoming has called for an improved me...

    Authors: Peter Diel, Christoph Röder, Gosia Perler, Thomas Vordemvenne, Matti Scholz, Frank Kandziora, Sebastian Fürderer, Soren Eiskjaer, Gianluca Maestretti, Robert Rotter, Lorin Michael Benneker and Paul Friedhelm Heini

    Citation: BMC Musculoskeletal Disorders 2013 14:233

    Content type: Research article

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  33. There is a growing tendency for complex proximal humerus fractures (PHF) in osteoporotic patients to be treated with reverse shoulder arthroplasty (RSA). It has been proposed that RSA has more benefits than ot...

    Authors: Georg Mattiassich, Lucian Lior Marcovici, Rolf Michael Krifter, Reinhold Ortmaier, Peter Wegerer and Albert Kroepfl

    Citation: BMC Musculoskeletal Disorders 2013 14:231

    Content type: Research article

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  34. Blood loss in hip and knee arthroplasties may necessitate allogeneic blood transfusions. Different blood-saving measures (BSMs) were introduced to reduce these transfusions. Purpose of the present study was to...

    Authors: Veronique MA Voorn, Perla J Marang-van de Mheen, Manon M Wentink, Cynthia So-Osman, Thea PM Vliet Vlieland, Ankie WMM Koopman-van Gemert, Rob GHH Nelissen and Leti Van Bodegom-Vos

    Citation: BMC Musculoskeletal Disorders 2013 14:230

    Content type: Research article

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  35. Bone marrow-derived mesenchymal stromal cells (BM-MSCs) play an important role in modern tissue engineering, while distinct variations of culture media compositions and supplements have been reported. Because ...

    Authors: Sebastien Hagmann, Babak Moradi, Sebastian Frank, Thomas Dreher, Peer Wolfgang Kämmerer, Wiltrud Richter and Tobias Gotterbarm

    Citation: BMC Musculoskeletal Disorders 2013 14:223

    Content type: Research article

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  36. Periprosthetic infection about the knee is a devastating complication that may affect between 1% and 5% of knee replacement. With over 79 000 knee replacements being implanted each year in the UK, periprosthet...

    Authors: James PM Masters, Nicholas A Smith, Pedro Foguet, Mike Reed, Helen Parsons and Andrew P Sprowson

    Citation: BMC Musculoskeletal Disorders 2013 14:222

    Content type: Research article

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  37. Anterior lumbar interbody fusion (ALIF) followed by pedicle screw fixation (PSF) is used to restore the height of the intervertebral disc and provide stability. Recently, stand-alone interbody cage with anteri...

    Authors: Kyung-Chul Choi, Kyeong-Sik Ryu, Sang-Ho Lee, Yeong Hyeon Kim, Sung Jae Lee and Chun-Kun Park

    Citation: BMC Musculoskeletal Disorders 2013 14:220

    Content type: Research article

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  38. Although percutaneous posterior-ring tension-band metallic plate and percutaneous iliosacral screws are used to fix unstable posterior pelvic ring fractures, the biomechanical stability and compatibility of bo...

    Authors: Hongwei Chen, Lijun Wu, Rongmei Zheng, Yan Liu, Yang Li and Zihai Ding

    Citation: BMC Musculoskeletal Disorders 2013 14:217

    Content type: Research article

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  39. Interleukin-1β (IL-1β) is a major mediator of local inflammation present in injured joints. In this study, we aimed at comparing the effect of IL-1β on engineered tissues from MCs, BMSCs and co-cultured MCs an...

    Authors: Anika Chowdhury, Louis W Bezuidenhout, Aillette Mulet-Sierra, Nadr M Jomha and Adetola B Adesida

    Citation: BMC Musculoskeletal Disorders 2013 14:216

    Content type: Research article

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  40. Symptomatic external snapping hip is a painful condition, where pain in the trochantor region and limitations of daily activity dominate clinical findings. The aetiology of symptomatic external snapping hip is...

    Authors: Julie S Jacobsen, Uwe G Kersting, Michael S Rathleff, Ole Simonsen, Kjeld Søballe and Michael Ulrich

    Citation: BMC Musculoskeletal Disorders 2013 14:212

    Content type: Research article

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  41. The aim of the present study was to compare one-year-follow-up data on disability and health-related quality of life (HRQoL) between spinal fusion patients and age- and sex-matched general population.

    Authors: Liisa Pekkanen, Marko H Neva, Hannu Kautiainen, Joost Dekker, Kirsi Piitulainen, Marko Wahlman and Arja Häkkinen

    Citation: BMC Musculoskeletal Disorders 2013 14:211

    Content type: Research article

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  42. Little is known about the impact of the reason for revision total hip arthroplasty (THA) on the outcomes following revision THA. In this study, our objective was to assess the association of operative diagnosi...

    Authors: Jasvinder A Singh and David G Lewallen

    Citation: BMC Musculoskeletal Disorders 2013 14:210

    Content type: Research article

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  43. The use of Computer Assisted Surgery (CAS) for knee replacements is intended to improve the alignment of knee prostheses in order to reduce the number of revision operations. Is the cost effectiveness of compu...

    Authors: Øystein Gøthesen, James Slover, Leif Havelin, Jan Erik Askildsen, Henrik Malchau and Ove Furnes

    Citation: BMC Musculoskeletal Disorders 2013 14:202

    Content type: Research article

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  44. Reproducible and suitable animal models are required for in vivo experiments to investigate new biodegradable and osteoinductive biomaterials for augmentation of bones at risk for osteoporotic fractures. Sheep ha...

    Authors: Karina Klein, Enrico Zamparo, Peter W Kronen, Katharina Kämpf, Mariano Makara, Thomas Steffen and Brigitte von Rechenberg

    Citation: BMC Musculoskeletal Disorders 2013 14:200

    Content type: Research article

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  45. The Forkhead/Fox transcription factor Foxc2 is a critical regulator of osteogenesis and angiogenesis of cells. Bone marrow mesenchymal stem cells (BMSCs) have the capacity to differentiate into osteoblasts, ch...

    Authors: Wulin You, Hongwei Gao, Lihong Fan, Dapeng Duan, Chunsheng Wang and Kunzheng Wang

    Citation: BMC Musculoskeletal Disorders 2013 14:199

    Content type: Research article

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  46. Culturing of the sonication fluid of removed implants has proven to be more sensitive than conventional periprosthetic tissue culture for the microbiological diagnosis of prosthetic joint infection. Since bact...

    Authors: Massimo Mariconda, Tiziana Ascione, Giovanni Balato, Renato Rotondo, Francesco Smeraglia, Giovan Giuseppe Costa and Marco Conte

    Citation: BMC Musculoskeletal Disorders 2013 14:193

    Content type: Research article

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  47. The Dynesys system provides stability for destabilized spines while preserving segmental motion. However, clinical studies have demonstrated that the Dynesys system does not prevent adjacent segment disease. M...

    Authors: Shih-Liang Shih, Chien-Lin Liu, Li-Ying Huang, Chang-Hung Huang and Chen-Sheng Chen

    Citation: BMC Musculoskeletal Disorders 2013 14:191

    Content type: Research article

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  48. In the anatomic double-bundle ACL reconstruction, 2 femoral tunnel positions are particularly critical to obtain better clinical results. Recently, a few studies have reported quantitative identification metho...

    Authors: Shuken Kai, Eiji Kondo, Nobuto Kitamura, Yasuyuki Kawaguchi, Masayuki Inoue, Andrew A Amis and Kazunori Yasuda

    Citation: BMC Musculoskeletal Disorders 2013 14:189

    Content type: Research article

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