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Orthopedics and biomechanics

Section edited by Umile Giuseppe Longo

This section concerns all aspects of orthopedic treatments for musculoskeletal disorders including but not limited to: orthopedic surgery and related biomechanics, non-surgical orthoses, and tissue engineering.

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  1. A double-network (DN) gel, which is composed of poly(2-acrylamido-2-methylpropanesulfonic acid) and poly(N,N’-dimethyl acrylamide), can induce hyaline cartilage regeneration in vivo in a large osteochondral defec...

    Authors: Hidetoshi Matsuda, Nobuto Kitamura, Takayuki Kurokawa, Kazunobu Arakaki, Jian Ping Gong, Fuminori Kanaya and Kazunori Yasuda

    Citation: BMC Musculoskeletal Disorders 2013 14:50

    Content type: Research article

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  2. Metal-on-metal hip resurfacing arthroplasty (HR) has been gaining popularity especially for young and active patients. Although different series report good mid-term results, the long-term outcome and failure ...

    Authors: Francesca Salamanna, Milena Fini, Annapaola Parrilli, Matteo Cadossi, Nicolò Nicoli Aldini, Gianluca Giavaresi, Deianira Luciani and Sandro Giannini

    Citation: BMC Musculoskeletal Disorders 2013 14:47

    Content type: Research article

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  3. Extracorporeal shockwave therapy (ESWT) shows chondroprotective effect in osteoarthritis of the rat knees. However, the ideal number of ESWT is unknown. This study investigated the effects of different numbers...

    Authors: Ching-Jen Wang, Shan-Ling Hsu, Lin-Hsiu Weng, Yi-Chih Sun and Feng-Sheng Wang

    Citation: BMC Musculoskeletal Disorders 2013 14:44

    Content type: Research article

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  4. The number of total hip arthroplasties in patients under 30 years is increasing over the years. Almost all of them will face at least one or more future revisions in their life. Therefore, the implant used sho...

    Authors: Marloes WJL Schmitz, Vincent JJF Busch, Jean WM Gardeniers, Jan CM Hendriks, René PH Veth and B Willem Schreurs

    Citation: BMC Musculoskeletal Disorders 2013 14:37

    Content type: Research article

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  5. Knee extensor strength and knee extension range of motion (ROM) are important predictors of physical function in patients with a total knee arthroplasty (TKA). However, the relationship between the two knee me...

    Authors: Yong-Hao Pua, Peck-Hoon Ong, Hwei-Chi Chong, William Yeo, Celia Tan and Ngai-Nung Lo

    Citation: BMC Musculoskeletal Disorders 2013 14:33

    Content type: Research article

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  6. In this study we evaluated a novel approach to guide the bone marrow-driven articular cartilage repair response in skeletally aged rabbits. We hypothesized that dispersed chitosan particles implanted close to ...

    Authors: Charles-Hubert Lafantaisie-Favreau, Jessica Guzmán-Morales, Jun Sun, Gaoping Chen, Adam Harris, Thomas D Smith, Alberto Carli, Janet Henderson, William D Stanish and Caroline D Hoemann

    Citation: BMC Musculoskeletal Disorders 2013 14:27

    Content type: Research article

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  7. Intimate partner violence (IPV) is a serious health issue. There have been widespread research efforts in the area of IPV over the past several decades, primarily focusing on obstetrics, emergency medicine, an...

    Authors: Sheila Sprague, Kim Madden, Sonia Dosanjh, Katelyn Godin, J Carel Goslings, Emil H Schemitsch and Mohit Bhandari

    Citation: BMC Musculoskeletal Disorders 2013 14:23

    Content type: Review

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  8. Proper blood pressure control during surgical procedures such as total joint arthroplasty (TJA) is considered critical to good outcome. There is poor understanding of the pre-operative risk factors for poor in...

    Authors: Benedict U Nwachukwu, Jamie E Collins, Emily P Nelson, Mercedes Concepcion, Thomas S Thornhill and Jeffrey N Katz

    Citation: BMC Musculoskeletal Disorders 2013 14:20

    Content type: Research article

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  9. We present a descriptive and retrospective analysis of revision total hip arthroplasties (THA) using the MRP-TITAN stem (Peter Brehm, Weisendorf, GER) with distal diaphyseal fixation and metaphyseal defect aug...

    Authors: Matthias D Wimmer, Thomas M Randau, Moritz C Deml, Rudolf Ascherl, Ulrich Nöth, Raimund Forst, Nadine Gravius, Dieter Wirtz and Sascha Gravius

    Citation: BMC Musculoskeletal Disorders 2013 14:19

    Content type: Research article

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  10. The ovine stifle joint is an important location for investigations on the repair of articular cartilage defects in preclinical large animals. The classical medial parapatellar approach to the femoral trochlea ...

    Authors: Patrick Orth and Henning Madry

    Citation: BMC Musculoskeletal Disorders 2013 14:5

    Content type: Technical advance

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  11. The most common mechanical failure in the internal fixation of trochanteric hip fractures is the cut-out of the sliding screw through the femoral head. Several factors that influence this complication have bee...

    Authors: Alicja J Bojan, Claudia Beimel, Gilbert Taglang, David Collin, Carl Ekholm and Anders Jönsson

    Citation: BMC Musculoskeletal Disorders 2013 14:1

    Content type: Research article

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  12. Existent biomechanical studies on hip osteoarthritic gait have primarily focused on the end stage of disease. Consequently, there is no clear consensus on which specific gait parameters are of most relevance f...

    Authors: Ingrid Eitzen, Linda Fernandes, Lars Nordsletten and May Arna Risberg

    Citation: BMC Musculoskeletal Disorders 2012 13:258

    Content type: Research article

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    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2015 16:52

  13. Distal radius fractures (DRF) are one of the most common fractures and often need surgical treatment, which has been validated through biomechanical tests. Currently a number of different fracture models are u...

    Authors: Sebastian Felix Baumbach, Enrico Dall’Ara, Patrick Weninger, Anna Antoni, Hannes Traxler, Martin Dörr and Philippe K Zysset

    Citation: BMC Musculoskeletal Disorders 2012 13:252

    Content type: Research article

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  14. Numerous papers have been published examining risk factors for revision of primary total hip arthroplasty (THA), but there have been no comprehensive systematic literature reviews that summarize the most recen...

    Authors: Julian JZ Prokopetz, Elena Losina, Robin L Bliss, John Wright, John A Baron and Jeffrey N Katz

    Citation: BMC Musculoskeletal Disorders 2012 13:251

    Content type: Research article

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  15. A number of factors have been identified as influencing total knee arthroplasty outcomes, including patient factors such as gender and medical comorbidity, technical factors such as alignment of the prosthesis...

    Authors: Rick L Lau, Anthony V Perruccio, Rajiv Gandhi and Nizar N Mahomed

    Citation: BMC Musculoskeletal Disorders 2012 13:250

    Content type: Research article

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  16. The purpose of our study was to prospectively report the clinical results of 280 consecutive hips (240 patients) who received a ReCap Hip Resurfacing System implant (Biomet Inc., Warsaw, USA) in a single distr...

    Authors: Walter van der Weegen, Henk J Hoekstra, Thea Sijbesma, Shennah Austen and Rudolf W Poolman

    Citation: BMC Musculoskeletal Disorders 2012 13:247

    Content type: Research article

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  17. Bone grafts are frequently used in orthopaedic surgery. Graft remodelling is advantageous but can occur too quickly, and premature bone resorption might lead to decreased mechanical integrity of the graft. Bis...

    Authors: Ola Belfrage, Hanna Isaksson and Magnus Tägil

    Citation: BMC Musculoskeletal Disorders 2012 13:240

    Content type: Research article

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  18. One major drawback in measuring ground-reaction forces during running is that it is time consuming to get representative ground-reaction force (GRF) values with a traditional force platform. An instrumented fo...

    Authors: Bas Kluitenberg, Steef W Bredeweg, Sjouke Zijlstra, Wiebren Zijlstra and Ida Buist

    Citation: BMC Musculoskeletal Disorders 2012 13:235

    Content type: Research article

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  19. The posterior cruciate ligament (PCL) plays an important role in maintaining physiological kinematics and function of the knee joint. To date mainly in-vitro models or combined magnetic resonance and fluorosco...

    Authors: Ruediger von Eisenhart-Rothe, Ulrich Lenze, Stefan Hinterwimmer, Florian Pohlig, Heiko Graichen, Thomas Stein, Frederic Welsch and Rainer Burgkart

    Citation: BMC Musculoskeletal Disorders 2012 13:231

    Content type: Research article

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  20. Platelet Rich Plasma (PRP), a blood-derived product rich in growth factors, is a promising treatment for cartilage defects but there is still a lack of clinical evidence. The aim of this study is to show, thro...

    Authors: Giuseppe Filardo, Elizaveta Kon, Alessandro Di Martino, Berardo Di Matteo, Maria Letizia Merli, Annarita Cenacchi, Pier Maria Fornasari and Maurilio Marcacci

    Citation: BMC Musculoskeletal Disorders 2012 13:229

    Content type: Research article

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  21. Ankle fractures are one of the more commonly occurring forms of trauma managed by orthopaedic teams worldwide. The impacts of these injuries are not restricted to pain and disability caused at the time of the ...

    Authors: Steven M McPhail, Joel Dunstan, Julie Canning and Terry P Haines

    Citation: BMC Musculoskeletal Disorders 2012 13:224

    Content type: Research article

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  22. Joint replacement is an effective intervention for people with advanced arthritis, although there is an important minority of patients who do not improve post-operatively. There is a need for robust evidence o...

    Authors: Vikki Wylde, Ashley W Blom, Stijn Bolink, Luke Brunton, Paul Dieppe, Rachael Gooberman-Hill, Bernd Grimm, Cindy Mann and Erik Lenguerrand

    Citation: BMC Musculoskeletal Disorders 2012 13:220

    Content type: Study protocol

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  23. Intramedullary nailing of pertrochanteric femoral fractures has grown in popularity over the past 2 decades likely because this procedure is associated with a low risk for postoperative morbidity and a fast re...

    Authors: Christian Giessauf, Mathias Glehr, Gerwin A Bernhardt, Franz J Seibert, Karl Gruber, Patrick Sadoghi, Andreas Leithner and Gerald Gruber

    Citation: BMC Musculoskeletal Disorders 2012 13:214

    Content type: Research article

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  24. Simvastatin increases the expression of bone morphogenetic protein 2 (BMP-2) in osteoblasts, therefore it is important to investigate the influence of statins on bone formation, fracture healing and implant in...

    Authors: Stephan Pauly, David A Back, Kathrin Kaeppler, Norbert P Haas, Gerhard Schmidmaier and Britt Wildemann

    Citation: BMC Musculoskeletal Disorders 2012 13:208

    Content type: Research article

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  25. Polymethylmethacrylate (PMMA) is commonly used for clinical applications. However, the short handling time increases the probability of a surgeon missing the crucial period in which the cement maintains its id...

    Authors: Po-Liang Lai, Ching-Lung Tai, I-Ming Chu, Tsai-Sheng Fu, Lih-Huei Chen and Wen-Jer Chen

    Citation: BMC Musculoskeletal Disorders 2012 13:198

    Content type: Research article

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  26. Possible immunization to blood group or other antigens and subsequent inhibition of remodeling or incorporation after use of untreated human bone allograft was described previously. This study presents the imm...

    Authors: Falk Mittag, Matthias Straub, Richard Schäfer, Torsten Kluba and Ingmar Ipach

    Citation: BMC Musculoskeletal Disorders 2012 13:187

    Content type: Research article

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  27. Tissue adhesives are useful means for various medical procedures. Since varying requirements cause that a single adhesive cannot meet all needs, bond strength testing remains one of the key applications used t...

    Authors: Tilo Dehne, Rolf Zehbe, Jan Philipp Krüger, Aneliya Petrova, Rafael Valbuena, Michael Sittinger, Helmut Schubert and Jochen Ringe

    Citation: BMC Musculoskeletal Disorders 2012 13:175

    Content type: Technical advance

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  28. Titanium (TTN) cages have a higher modulus of elasticity when compared with polyetheretherketone (PEEK) cages. This suggests that TTN-cages could show more frequent cage subsidence after anterior cervical disc...

    Authors: Mario Cabraja, Soner Oezdemir, Daniel Koeppen and Stefan Kroppenstedt

    Citation: BMC Musculoskeletal Disorders 2012 13:172

    Content type: Research article

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  29. Femoral neck fractures with a vertical orientation have been associated with an increased risk for failure as they are both axial and rotational unstable and experience increased shear forces compared to the c...

    Authors: Anders Enocson and Lasse J Lapidus

    Citation: BMC Musculoskeletal Disorders 2012 13:171

    Content type: Research article

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  30. The complications of reversed total shoulder arthroplasty (RTSA) requiring an additional intervention, their treatment options and outcome are poorly known. It was therefore the purpose of this retrospective s...

    Authors: Mazda Farshad, Marion Grögli, Sabrina Catanzaro and Christian Gerber

    Citation: BMC Musculoskeletal Disorders 2012 13:160

    Content type: Research article

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  31. Most modern spinal implants contain titanium and remain in the patient’s body permanently. Local and systemic effects such as tissue necrosis, osteolysis and malignant cell transformation caused by implants ha...

    Authors: Ingmar Ipach, Ralf Schäfer, Falk Mittag, Carmen Leichtle, Petra Wolf and Torsten Kluba

    Citation: BMC Musculoskeletal Disorders 2012 13:159

    Content type: Research article

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  32. The aim of this randomized clinical trial was to assess the effect of early orthodontic treatment for unilateral posterior cross bite in the late deciduous and early mixed dentition using orthopedic parameters.

    Authors: Carsten Lippold, Tatjana Moiseenko, Burkhard Drerup, Markus Schilgen, András Végh and Gholamreza Danesh

    Citation: BMC Musculoskeletal Disorders 2012 13:151

    Content type: Research article

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  33. To investigate the efficacy of the sole core decompression surgery for the treatment of steroid-induced femoral head osteonecrosis.

    Authors: Wei Wang, Liying Liu, Xiaoqian Dang, Shuqiang Ma, Mingyu Zhang and Kunzheng Wang

    Citation: BMC Musculoskeletal Disorders 2012 13:142

    Content type: Research article

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  34. Retrospective assessment of surgery outcome is considered problematic. The aims of this study were to evaluate the reproducibility and accuracy of a retrospective outcome assessment of lumbar spinal stenosis s...

    Authors: Pekka Kuittinen, Timo Juhani Aalto, Tapani Heikkilä, Ville Leinonen, Sakari Savolainen, Petri Sipola, Heikki Kröger, Veli Turunen and Olavi Airaksinen

    Citation: BMC Musculoskeletal Disorders 2012 13:83

    Content type: Research article

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  35. Metal-on-metal hip resurfacing is an alternative to metal-on-metal total hip arthroplasty, especially for young and physically active patients. However, wear which might be detected by increased serum ion leve...

    Authors: W Maurer-Ertl, J Friesenbichler, P Sadoghi, M Pechmann, M Trennheuser and A Leithner

    Citation: BMC Musculoskeletal Disorders 2012 13:56

    Content type: Research article

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  36. The common practice for insertion of distal locking screws of intramedullary nails is a freehand technique under fluoroscopic control. The process is technically demanding, time-consuming and afflicted to cons...

    Authors: Markus Windolf, Josh Schroeder, Ladina Fliri, Benno Dicht, Meir Liebergall and R Geoff Richards

    Citation: BMC Musculoskeletal Disorders 2012 13:8

    Content type: Technical advance

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  37. Low bone mineral density (BMD) and falls are common problems encountered in the postmenopausal women. The purpose was to evaluate the association between postural balance and BMD in postmenopausal women and it...

    Authors: Luciana Mendes Cangussu, Jorge Nahas-Neto, Eliana Aguiar Petri Nahas, Ana Beatriz Cesar Rodrigues Barral, Davi de Araujo Buttros and Gilberto Uemura

    Citation: BMC Musculoskeletal Disorders 2012 13:2

    Content type: Research article

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  38. The optimal treatment of displaced femoral neck fractures in patients over 60 years is controversial. While much research has focused on the impact of total hip arthroplasty (THA) and hemiarthroplasty (HA) on ...

    Authors: Noor Alolabi, Bashar Alolabi, Raman Mundi, Paul J Karanicolas, Jonathan D Adachi and Mohit Bhandari

    Citation: BMC Musculoskeletal Disorders 2011 12:289

    Content type: Research article

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  39. The operative treatment of adult degenerative scoliosis combined with osteoporosis increase following the epidemiological development. Studies have confirmed that screws in osteoporotic spines have significant...

    Authors: Yang Xie, Qiang Fu, Zi-qiang Chen, Zhi-cai Shi, Xiao-dong Zhu, Chuan-feng Wang and Ming Li

    Citation: BMC Musculoskeletal Disorders 2011 12:286

    Content type: Research article

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  40. Unicameral (or simple) bone cysts (UBC) are benign tumours most often located in long bones of children and adolescents. Pathological fractures are common, and due to high recurrence rates, these lesions remai...

    Authors: Sébastien Hagmann, Florian Eichhorn, Babak Moradi, Tobias Gotterbarm, Thomas Dreher, Burkhard Lehner and Felix Zeifang

    Citation: BMC Musculoskeletal Disorders 2011 12:281

    Content type: Research article

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  41. Enhancing osteogenic capabilities of bone matrix for the treatment of fractures and segmental defects using growth factors is an active area of research. Recently, synthetic peptides like AC- 100, TP508 or p-1...

    Authors: Thomas Vordemvenne, Jürgen RJ Paletta, Rene Hartensuer, Thomas Pap, Michael J Raschke and Sabine Ochman

    Citation: BMC Musculoskeletal Disorders 2011 12:263

    Content type: Research article

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  42. Hip fracture is associated with high mortality. Cardiovascular disease and other comorbidities requiring long-term anticoagulant medication are common in these mostly elderly patients. The objective of our obs...

    Authors: Annika M Kragh, Markus Waldén, Anna Apelqvist, Philippe Wagner and Isam Atroshi

    Citation: BMC Musculoskeletal Disorders 2011 12:254

    Content type: Research article

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  43. Knee size and body size differ in Asians compared with Caucasians. Nevertheless, many total knee arthroplasty (TKA) prostheses used worldwide are made for Western Caucasian subjects. As a result, an Asian's kn...

    Authors: Kunihiro Hosaka, Shu Saito, Takao Ishii, Sei Mori, Takanobu Sumino and Yasuaki Tokuhashi

    Citation: BMC Musculoskeletal Disorders 2011 12:251

    Content type: Research article

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  44. Patients undergoing total knee arthroplasty (TKA) often experience strength deficits both pre- and post-operatively. As these deficits may have a direct impact on functional recovery, strength assessment shoul...

    Authors: Ian FH Koblbauer, Yannick Lambrecht, Micheline LM van der Hulst, Camille Neeter, Raoul HH Engelbert, Rudolf W Poolman and Vanessa A Scholtes

    Citation: BMC Musculoskeletal Disorders 2011 12:249

    Content type: Research article

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  45. Mast cells contribute to tissue repair in fibrous tissues by stimulating proliferation of fibroblasts through the release of tryptase which activates protease-activated receptor-2 (PAR-2). The possibility that...

    Authors: Elise Duchesne, Marie-Hélène Tremblay and Claude H Côté

    Citation: BMC Musculoskeletal Disorders 2011 12:235

    Content type: Research article

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  46. There have been few studies focusing on the curve pattern of scoliosis caused by lumbar disc herniation (LDH) in adolescents and the natural history of scoliosis after discectomy. The current study was carried...

    Authors: Zezhang Zhu, Qinghua Zhao, Bin Wang, Yang Yu, Bangping Qian, Yitao Ding and Yong Qiu

    Citation: BMC Musculoskeletal Disorders 2011 12:216

    Content type: Research article

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