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Orthopedics and biomechanics

This section concerns all aspects of orthopedic treatments for musculoskeletal disorders including but not limited to: orthopedic surgery and related biomechanics, non-surgical orthoses, and tissue engineering.

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  1. It is very rare for clear cell sarcomas (CCS) to arise in the bone. During diagnosis, it is important to distinguish primary CCS of bone from bone metastasis of melanoma because this difference fundamentally c...

    Authors: Yuta Kubota, Kazuhiro Tanaka, Masanori Hisaoka, Tsutomu Daa, Tatsuya Iwasaki, Masanori Kawano, Ichiro Itonaga and Hiroshi Tsumura

    Citation: BMC Musculoskeletal Disorders 2021 22:99

    Content type: Case report

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  2. This study aimed to assess the radii of the distal and posterior articular surfaces of the medial femoral condyle in a Chinese population and provide detailed parameters of the knee joint for the future design...

    Authors: Feifan Lu, Xiaowei Sun, Weiguo Wang, Qidong Zhang and Wanshou Guo

    Citation: BMC Musculoskeletal Disorders 2021 22:95

    Content type: Research article

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  3. Bone morphogenetic proteins (BMPs) induce osteogenesis in various environments. However, when BMPs are used alone in the bone marrow environment, the maintenance of new bone formation is difficult owing to vig...

    Authors: Hideki Ueyama, Yoichi Ohta, Yuuki Imai, Akinobu Suzuki, Ryo Sugama, Yukihide Minoda, Kunio Takaoka and Hiroaki Nakamura

    Citation: BMC Musculoskeletal Disorders 2021 22:94

    Content type: Research article

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  4. Patellar instability (PI) often increases the possibility of lateral patellar dislocation and early osteoarthritis. The molecular mechanism of early articular cartilage degeneration during patellofemoral osteo...

    Authors: Wei Lin, Huijun Kang, Yike Dai, Yingzhen Niu, Guangmin Yang, Jinghui Niu, Ming Li and Fei Wang

    Citation: BMC Musculoskeletal Disorders 2021 22:90

    Content type: Research article

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  5. Medial open-wedge high tibial osteotomy (HTO) is an effective and safe treatment method for medial osteoarthritis of the knee. However, unintended changes in the posterior tibial slope (PTS) may occur. Several...

    Authors: Sang Won Moon, Ji Young Ryu, Sung-Jae Lee, Sang Won Woo, Sin Hyung Park and Young Choi

    Citation: BMC Musculoskeletal Disorders 2021 22:89

    Content type: Research article

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  6. We present a case of an immense unprecedented tibial bone lengthening of 33.5 cm. The management of chronic osteomyelitis of the right tibia with subtotal tibial bone defect, talus defect and equinus ankle def...

    Authors: Abdulnassir Ali, Ying Ren, Chun-Hao Zhou, Jia Fang and Cheng-He Qin

    Citation: BMC Musculoskeletal Disorders 2021 22:88

    Content type: Case report

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  7. Percutaneous anterior odontoid screw fixation for odontoid fractures remains challenging due to the complex anatomy of the craniocervical junction. We designed a new guide instrument to help with the placement...

    Authors: Yan Wang, Min Li, Guanxing Cui, Jing Li, Zhiliang Guo, Dahai Zhang, Haijun Teng and Haijiang Lu

    Citation: BMC Musculoskeletal Disorders 2021 22:87

    Content type: Research article

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  8. Previous research and published literature indicate that some patients with spinal diseases who underwent percutaneous transforaminal endoscopic decompression (PTED) still suffer some discomfort in the early r...

    Authors: Li-sheng Hou, Dong Zhang, Feng Ge, Hai-feng Li and Tian-jun Gao

    Citation: BMC Musculoskeletal Disorders 2021 22:83

    Content type: Case report

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  9. Cervical disc replacement (CDR) has been widely used to treat one- and two-level cervical degenerative disc disease. Studies have shown the effectiveness of CDR in preserving range of motion (ROM) and delaying...

    Authors: Xiaofei Wang, Yang Meng, Hao Liu, Hua Chen, Beiyu Wang and Ying Hong

    Citation: BMC Musculoskeletal Disorders 2021 22:82

    Content type: Research article

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  10. This prospective cohort study reports on a modified technique, namely precise safety decompression via double percutaneous lumbar foraminoplasty (DPLF) and percutaneous endoscopic lumbar decompression (PELD) f...

    Authors: Yu Wang, Mingyan Deng, Hao Wu, Ye Wu, Chuan Guo, Dongfeng Zhang and Qingquan Kong

    Citation: BMC Musculoskeletal Disorders 2021 22:80

    Content type: Research article

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  11. Intervertebral disc degeneration (IVDD) is a primary cause of degenerative disc diseases; however, the mechanisms underlying the degeneration remain unclear. The immunoinflammatory response plays an important ...

    Authors: Zhu Guo, Chensheng Qiu, Christina Mecca, Yang Zhang, Jiang Bian, Yan Wang, Xiaolin Wu, Tianrui Wang, Weiliang Su, Xianglin Li, Wei Zhang, Bohua Chen and Hongfei Xiang

    Citation: BMC Musculoskeletal Disorders 2021 22:77

    Content type: Research article

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  12. Standard balloon kyphoplasty represents a well-established treatment option for osteoporotic vertebral compression fractures. Aim of the present study was to evaluate two different methods of percutaneous augm...

    Authors: Antonio Krüger, Martin Bäumlein, Tom Knauf, Hugues Pascal-Moussellard, Steffen Ruchholtz and Ludwig Oberkircher

    Citation: BMC Musculoskeletal Disorders 2021 22:76

    Content type: Research article

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  13. If bone union is expected, conservative treatment is generally selected for lumbar spondylolysis. However, sometimes conservative treatments are unsuccessful. We sought to determine the factors associated with...

    Authors: Masaki Tatsumura, Hisanori Gamada, Shun Okuwaki, Fumihiko Eto, Katsuya Nagashima, Takeshi Ogawa, Takeo Mammoto, Atsushi Hirano, Masao Koda and Masashi Yamazaki

    Citation: BMC Musculoskeletal Disorders 2021 22:75

    Content type: Research article

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  14. Tibial intercondylar eminence avulsion fractures occur primarily in adolescents and young adults. However, the incidence of such fractures is increasing in adults, concurrent with an increase in sports injurie...

    Authors: Yupeng Chu, Ting Hu, Mangmang Chen, Chendi Jiang, Zhuqi Wu and Junwu Shi

    Citation: BMC Musculoskeletal Disorders 2021 22:74

    Content type: Technical advance

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  15. The unicameral bone cyst (UBC) is a kind of benign tumor whose clinical treatments and efficacy are controversial. The purpose of this study was to evaluate the efficacy of the elastic stable intramedullary na...

    Authors: Ke-Xue Zhang, Wei Chai, Jia-Jia Zhao, Jun-Hao Deng, Zhan Peng and Ji-Ying Chen

    Citation: BMC Musculoskeletal Disorders 2021 22:73

    Content type: Research article

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  16. There is no recommended standard for positioning of a mouse for radiographic assessment of the spine. This is necessary to have reproducible radiographic data and avoid false positive results. The objective of...

    Authors: Zhe Yi Chen, Keith Dip Kei Luk, You Qiang Song, Bo Gao and Jason Pui Yin Cheung

    Citation: BMC Musculoskeletal Disorders 2021 22:72

    Content type: Research article

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  17. Percutaneous transforaminal endoscopy has been widely used to treat lumbar disc herniation (LDH), but the steep learning curve and difficulties in removing the calcified disc hinders the application of convent...

    Authors: Hao Wang, Tianyao Zhou, Yutong Gu and Zuoqin Yan

    Citation: BMC Musculoskeletal Disorders 2021 22:65

    Content type: Research article

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  18. Locked titanium nails are considered the reference treatment for metastatic bone lesions of the humerus in patients with aggressive histotypes, high risk of fracture or when estimated survival is lower than 6 ...

    Authors: Carmine Zoccali, Dario Attala, Mattia Pugliese, Alessandra Scotto di Uccio and Jacopo Baldi

    Citation: BMC Musculoskeletal Disorders 2021 22:63

    Content type: Research article

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  19. Displaced patellar fractures are commonly treated with open reduction and fixation with several different types of tension-band (TB) constructs. The main objective of this study was to compare the prevalence o...

    Authors: Xiao-zhong Zhu, Teng-li Huang, Hong-yi Zhu, Bing-bo Bao, Tao Gao, Xing-wei Li, Jun-qing Lin and Xian-You Zheng

    Citation: BMC Musculoskeletal Disorders 2021 22:60

    Content type: Research article

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  20. Full-endoscopic lumbar discectomy (FELD) is an alternative to posterior open surgery to treat a high-grade migrated herniated disc. However, because of the complexity of the surgery, success is dependent on th...

    Authors: Christopher Wu, Ching-Yu Lee, Sheng Chi Chen, Shao-Keh Hsu and Meng-Huang Wu

    Citation: BMC Musculoskeletal Disorders 2021 22:58

    Content type: Research article

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  21. Tibial shaft fractures (TSFs) are among the most common long bone injuries often resulting from high-energy trauma. To date, musculoskeletal complications such as fracture-related infection (FRI) and compromis...

    Authors: Willem-Jan Metsemakers, Kirsten Kortram, Nando Ferreira, Mario Morgenstern, Alexander Joeris, Hans-Christoph Pape, Christian Kammerlander, Sanjit Konda, Jong-Keon Oh, Peter V. Giannoudis, Kenneth A. Egol, William T. Obremskey, Michael H. J. Verhofstad and Michael Raschke

    Citation: BMC Musculoskeletal Disorders 2021 22:57

    Content type: Study protocol

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  22. No studies to date have elucidated the clinical factors associated with pedicle screw pull-out during or immediately after surgery. The aim of this study was to assess the frequency of pedicle screw pull-out b...

    Authors: Satoshi Sumiya, Kazuyuki Fukushima, Yoshiro Kurosa, Takashi Hirai, Hiroyuki Inose, Toshitaka Yoshii and Atsushi Okawa

    Citation: BMC Musculoskeletal Disorders 2021 22:55

    Content type: Research article

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  23. Temporary hemiepiphysiodesis (TH) using an eight-Plate implant is one of the most common surgeries used for the correction of coronal angular deformities around the knee in adolescents. However, few studies ha...

    Authors: Zhen-Zhen Dai, Zhen-Peng Liang, Hao Li, Jing Ding, Zhen-Kai Wu, Zi-Ming Zhang and Hai Li

    Citation: BMC Musculoskeletal Disorders 2021 22:53

    Content type: Research article

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  24. Transthyretin and immunoglobulin light-chain amyloidoses cause amyloid deposition throughout various organ systems. Recent evidence suggests that soft tissue amyloid deposits may lead to orthopedic conditions ...

    Authors: Austin E. Wininger, Brian M. Phelps, Jessica T. Le, Joshua D. Harris, Barry H. Trachtenberg and Shari R. Liberman

    Citation: BMC Musculoskeletal Disorders 2021 22:51

    Content type: Research article

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  25. This study aims to compare conservative versus surgical management for patients with full-thickness RC tear in terms of clinical and structural outcomes at 1 and 2 years of follow-up.

    Authors: Umile Giuseppe Longo, Laura Risi Ambrogioni, Vincenzo Candela, Alessandra Berton, Arianna Carnevale, Emiliano Schena and Vincenzo Denaro

    Citation: BMC Musculoskeletal Disorders 2021 22:50

    Content type: Research article

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  26. Aseptic loosening of glenoid implants is the primary revision cause in anatomic total shoulder arthroplasty (aTSA). While supported by biomechanical studies, the impact of glenoid bone quality, more specifical...

    Authors: Sandrine Mariaux, Raphaël Obrist, Alain Farron, Fabio Becce and Alexandre Terrier

    Citation: BMC Musculoskeletal Disorders 2021 22:49

    Content type: Research article

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  27. The introduction of reverse total shoulder arthroplasty (RSA) as a treatment option in complex proximal humeral fractures, has significantly extended the surgical armamentarium.

    Authors: AM Schwarz, GM Hohenberger, M Sauerschnig, M Niks, G Lipnik, G Mattiassich, M Zacherl, FJ Seibert and M Plecko

    Citation: BMC Musculoskeletal Disorders 2021 22:48

    Content type: Research article

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  28. Thoracic scoliosis has been shown to be associated with hypokyphosis in adolescent idiopathic scoliosis (AIS). However, the relationship of sagittal spino-pelvic parameters with different coronal curve pattern...

    Authors: Trixie Mak, Prudence Wing Hang Cheung, Teng Zhang and Jason Pui Yin Cheung

    Citation: BMC Musculoskeletal Disorders 2021 22:44

    Content type: Research article

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  29. Osteonecrosis of the femoral head is a common complication in the treatment of developmental dysplasia of the hip (DDH). While functional outcomes of affected patients are good in childhood, it is not clear ho...

    Authors: Avi Marks, Mario Cortina-Borja, Dror Maor, Aresh Hashemi-Nejad and Andreas Roposch

    Citation: BMC Musculoskeletal Disorders 2021 22:42

    Content type: Research article

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  30. The aim of this study was that to compare clinical results between the rounded rectangular femoral tunnel ACL reconstruction (RFTR) and the conventional round femoral tunnel ACL reconstruction using a hamstrin...

    Authors: Junsuke Nakase, Yasushi Takata, Kengo Shimozaki, Kazuki Asai, Rikuto Yoshimizu, Mitsuhiro Kimura and Hiroyuki Tsuchiya

    Citation: BMC Musculoskeletal Disorders 2021 22:38

    Content type: Research article

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  31. The Ilizarov segmental bone transport technique can be applied in the reconstruction of the bone defects with less invasive fashion and more versatility compared to other methods, while most studies were focus...

    Authors: Yanshi Liu, Maimaiaili Yushan, Zhenhui Liu, Jialin Liu, Chuang Ma and Aihemaitijiang Yusufu

    Citation: BMC Musculoskeletal Disorders 2021 22:36

    Content type: Research article

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  32. Large post-traumatic tibial bone defects combined with soft tissue defects are a common orthopedic clinical problem associated with poor outcomes when treated using traditional surgical methods. The study was ...

    Authors: Yong-Qing Xu, Xin-Yu Fan, Xiao-Qing He and Hong-Jie Wen

    Citation: BMC Musculoskeletal Disorders 2021 22:34

    Content type: Research article

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  33. Labral tear can be the initiating factor in the onset of hip osteoarthritis (HOA). However, the physiopathology of labral tear is not fully understood. Our aim was to compare synovial tissue inflammatory cytok...

    Authors: Tomohisa Koyama, Kentaro Uchida, Kensuke Fukushima, Yoshihisa Ohashi, Katsufumi Uchiyama, Gen Inoue, Naonobu Takahira and Masashi Takaso

    Citation: BMC Musculoskeletal Disorders 2021 22:33

    Content type: Research article

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  34. The aim of this paper is to evaluate the clinical and radiological outcomes of a fluted tapered modular distal-fixation stem at medium to long-term follow-up. The hypothesis of this investigation was to verify...

    Authors: Loris Perticarini, Stefano Marco Paolo Rossi, Alberto Fioruzzi, Eugenio Jannelli, Mario Mosconi and Francesco Benazzo

    Citation: BMC Musculoskeletal Disorders 2021 22:29

    Content type: Research article

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  35. To evaluate the clinical outcomes of arthroscopic tight fibrous band release in the treatment of adult moderate-to-severe gluteal fibrosis using anterior and posterior portals during mid-term follow-up.

    Authors: Shu-guang Gao, Wei-jie Liu, Ming Yang, Jing-ping Li, Chao Su, Shi-da Kuang, Jie-peng Xiong, Ke Chou, Zhi-yong He and Liang-jun Li

    Citation: BMC Musculoskeletal Disorders 2021 22:28

    Content type: Research article

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  36. The conventional infrapatellar approach to intramedullary nailing of tibial fractures adopts the supine high-flexion knee position. However, this has disadvantages including difficulty in obtaining the proxima...

    Authors: Jinzhu Zhao, Liang Qu, Peng Li, Changlong Tan and Chunsheng Tao

    Citation: BMC Musculoskeletal Disorders 2021 22:25

    Content type: Research article

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  37. Degenerative cartilage changes can be seen, in cases of lateral patellar compression syndrome, involving the patellofemoral joint. Hyaluronic acid is a natural component of the synovial fluid and responsible f...

    Authors: Sherwan A. Hamawandi

    Citation: BMC Musculoskeletal Disorders 2021 22:24

    Content type: Research article

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  38. Of late, periarticular analgesic injection (PAI) has become a common alternative treatment for pain following total hip arthroplasty (THA). However, the systemic effects of PAI containing corticosteroids in pa...

    Authors: Akira Hashimoto, Motoki Sonohata, Hirohito Hirata, Shunsuke Kawano, Shuichi Eto, Masaya Ueno and Masaaki Mawatari

    Citation: BMC Musculoskeletal Disorders 2021 22:19

    Content type: Research article

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  39. Utilization of a cage with a large footprint in lateral lumbar interbody fusion (LLIF) for the treatment of spondylolisthesis leads to a high fusion rate and neurological improvement owing to the indirect deco...

    Authors: Masanari Takami, Ryo Taiji, Motohiro Okada, Akihito Minamide, Hiroshi Hashizume and Hiroshi Yamada

    Citation: BMC Musculoskeletal Disorders 2021 22:17

    Content type: Technical advance

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  40. To assess the risk factors for blood transfusion in a great number of adolescent cases with different types of scoliosis who received scoliosis surgery.

    Authors: Yulei Dong, Ning Tang, Shengru Wang, Jianguo Zhang and Hong Zhao

    Citation: BMC Musculoskeletal Disorders 2021 22:13

    Content type: Research article

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  41. This study compared the clinical and functional outcomes of patients initially treated with observation or medical treatment with those of patients treated with local treatment (surgery alone or surgery with a...

    Authors: Shinji Tsukamoto, Piergiuseppe Tanzi, Andreas F. Mavrogenis, Manabu Akahane, Akira Kido, Yasuhito Tanaka, Marilena Cesari, Davide Maria Donati, Alessandra Longhi and Costantino Errani

    Citation: BMC Musculoskeletal Disorders 2021 22:12

    Content type: Research article

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  42. Bone cement leakage is a major complication in the treatment of percutaneous vertebroplasty for Kümmell’s disease, and the focus of close attention during the surgery. The purpose of this article was to invest...

    Authors: Ya-Ping Xiao, Ming-Jian Bei, Cui-Qing Yan and Jian-Zhong Chang

    Citation: BMC Musculoskeletal Disorders 2021 22:10

    Content type: Research article

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  43. Antibiotic-loaded bone cement, or antibiotic-impregnated polymethylmethacrylate (PMMA), were developed to prevent and treat bone and joint infections. Gentamicin is an antibiotic that is commonly used in combi...

    Authors: Wongthawat Liawrungrueang, Suwipa Ungphaiboon, Arnurai Jitsurong, Natnicha Ingviya, Boonsin Tangtrakulwanich and Varah Yuenyongviwat

    Citation: BMC Musculoskeletal Disorders 2021 22:5

    Content type: Research article

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  44. To compare the efficacy of three different fixation methods of fibula combined with external fixation of tibia for the treatment of extra-articular open fractures of distal tibia and fibula.

    Authors: Dong-Dong Sun, Dan Lv, Kun Zhou, Jian Chen, Li-Lan Gao and Ming-Lin Sun

    Citation: BMC Musculoskeletal Disorders 2021 22:1

    Content type: Research article

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