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Epidemiology of musculoskeletal disorders

Section edited by Anita Wluka

This section concerns all aspects of the epidemiology of musculoskeletal disorders including but not limited to: cohort studies, genetic association studies, and prevalence studies.

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  1. Hip effusion-synovitis may be relevant to osteoarthritis (OA) but is of uncertain etiology. The aim of this study was to describe the cross-sectional and longitudinal associations of hip effusion-synovitis wit...

    Authors: Harbeer Ahedi, Dawn Aitken, Leigh Blizzard, Flavia Cicuttini and Graeme Jones

    Citation: BMC Musculoskeletal Disorders 2020 21:533

    Content type: Research article

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  2. Knee osteoarthritis (OA) is known to be a progressive degenerative disorder; however, recent evidence suggests that inflammatory mediators contribute to cartilage degradation. Studies have reported that N-acet...

    Authors: Ying-Ting Yeh, Chung-Chao Liang, Chia-Ling Chang, Chung-Y. Hsu and Pei-Chen Li

    Citation: BMC Musculoskeletal Disorders 2020 21:531

    Content type: Database

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  3. The epidemiology, risk factors, and prevention of locomotive syndrome (LS) have been reported. However, the number of clinical studies about the efficacy of LS treatment, including surgery, has been limited. T...

    Authors: Satoshi Kato, Yuki Kurokawa, Tamon Kabata, Satoru Demura, Hidenori Matsubara, Yoshitomo Kajino, Yoshiyuki Okamoto, Hiroaki Kimura, Kazuya Shinmura, Kentaro Igarashi, Takaki Shimizu, Noritaka Yonezawa, Noriaki Yokogawa and Hiroyuki Tsuchiya

    Citation: BMC Musculoskeletal Disorders 2020 21:515

    Content type: Research article

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  4. Increased physical activity level is related to lower risk of depressive symptoms, and there is an inverse association between muscle strength and risk of depressive symptoms among the elderly. Although there ...

    Authors: Zhongyu Ren, Jianhua Cao, Yingke Li, Peng Cheng, Bing Cao, Zongji Hao, Hui Yao, Dongzhe Shi, Bin Liu, Chang Chen, Guang Yang, Li Peng and Liya Guo

    Citation: BMC Musculoskeletal Disorders 2020 21:510

    Content type: Research article

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  5. Sarcopenia, cachexia and frailty have overlapping features and clinical consequences, but often go unrecognized. The objective was to detect patients described by clinicians as having sarcopenia, cachexia or f...

    Authors: Ranjani N. Moorthi, Ziyue Liu, Sarah A. El-Azab, Lauren R. Lembcke, Matthew R. Miller, Andrea A. Broyles and Erik A. Imel

    Citation: BMC Musculoskeletal Disorders 2020 21:508

    Content type: Research article

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  6. Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder characterized by extraskeletal heterotopic ossification. It is well recognized that FOP can lead to a devastating condition of disa...

    Authors: Dunmin She, Ran Li, Ping Fang, Guannan Zong, Ying Xue and Keqin Zhang

    Citation: BMC Musculoskeletal Disorders 2020 21:152

    Content type: Research article

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  7. Fractures have dire consequences including pain, immobility, and death. People receiving home care are at higher risk for fractures than the general population. Yet, current fracture risk assessment tools requ...

    Authors: Caitlin McArthur, George Ioannidis, Micaela Jantzi, Jonathon D. Adachi, Lora Giangregorio, John Hirdes and Alexandra Papaioannou

    Citation: BMC Musculoskeletal Disorders 2020 21:499

    Content type: Research article

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  8. Osteoarthritis (OA) is the most prevalent type of arthritis, which commonly involves inflammation in the articular cartilage in OA pathogenesis. MicroRNAs (miRNAs) play essential roles in the regulation and pa...

    Authors: Hong Pan, Huming Dai, Linzhi Wang, Silong Lin, Yuefeng Tao, Yi Zheng, Renyi Jiang, Fan Fang and Yifan Wu

    Citation: BMC Musculoskeletal Disorders 2020 21:486

    Content type: Research article

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  9. To evaluate whether knee osteoarthritis (OA) manifestations predict depression and anxiety using cross-sectional and longitudinal prediction models.

    Authors: Eric C. Sayre, John M. Esdaile, Jacek A. Kopec, Joel Singer, Hubert Wong, Anona Thorne, Ali Guermazi, Savvas Nicolaou and Jolanda Cibere

    Citation: BMC Musculoskeletal Disorders 2020 21:467

    Content type: Research article

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  10. Multiple knee ligament injuries combined with extensor apparatus rupture are serious and complex knee injuries that are rare in clinical practice. The management is extremely challenging and controversial.

    Authors: Daohong Zhao, Zhongde Yang, Changsha Wu, Jia Zhong, Xizong Zhou, Jinghua Li, Yan Li, Yongsheng Lu and Duo Shen

    Citation: BMC Musculoskeletal Disorders 2020 21:450

    Content type: Research article

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  11. The impact of comorbidity on the risk of revision in patients undergoing Total Knee arthroplasty (TKA) and Total Hip Arthroplasty (THA) is not currently well known. The aim of this study was to analyze the imp...

    Authors: Jorge Arias-de la Torre, Kayla Smith, Alexandru Dregan, Jose M. Valderas, Jonathan P. Evans, Daniel Prieto-Alhambra, Luis Lozano, Antonio J. Molina, Vicente Martín, Laia Domingo, Laura Muñoz and Mireia Espallargues

    Citation: BMC Musculoskeletal Disorders 2020 21:447

    Content type: Research article

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  12. Many patients report postoperative pain, limited improvement in physical function and poor quality of life (QOL) after knee replacement surgery. Our study uses baseline predictors of change to investigate the ...

    Authors: Paola Siviero, Anna Marseglia, Carlo Biz, Augusto Rovini, Pietro Ruggieri, Roberto Nardacchione and Stefania Maggi

    Citation: BMC Musculoskeletal Disorders 2020 21:436

    Content type: Research article

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  13. Locomotive syndrome (LoS) is defined as the loss of mobility due to age-related impairment of motor organs. The purpose of this study was to evaluate the prevalence and severity of LoS, muscular strength and b...

    Authors: Ryosuke Tokida, Shota Ikegami, Jun Takahashi, Yoshikazu Ido, Ayaka Sato, Noriko Sakai, Hiroshi Horiuchi and Hiroyuki Kato

    Citation: BMC Musculoskeletal Disorders 2020 21:431

    Content type: Research article

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  14. Age-related height loss is a normal physical change that occurs in all individuals over 50 years of age. Although many epidemiological studies on height loss have been conducted worldwide, none have been long-...

    Authors: Mutsuya Shimizu, Tetsuya Kobayashi, Hisashi Chiba, Issei Senoo, Hiroshi Ito, Keisuke Matsukura and Senri Saito

    Citation: BMC Musculoskeletal Disorders 2020 21:422

    Content type: Research article

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  15. To guide the selection of treatments for spinal metastases, the expected survival time is one of the most important determinants. Few scoring systems are fully applicable for spinal metastasis secondary to pro...

    Authors: Zhong-yu Gao, Tao Zhang, Hui Zhang, Cheng-gang Pang and Wen-xue Jiang

    Citation: BMC Musculoskeletal Disorders 2020 21:388

    Content type: Research article

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  16. The Glenohumeral internal-rotation deficit (GIRD) is related to the altered eccentric external-rotator (ER), the concentric internal-rotator (IR), muscle strength, and the ER: IR ratio. GIRD has been documente...

    Authors: Mohsen Moradi, Malihe Hadadnezhad, Amir Letafatkar, Zohre Khosrokiani and Julien S. Baker

    Citation: BMC Musculoskeletal Disorders 2020 21:376

    Content type: Research article

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  17. We sought to report the prevalence of fragility fracture patients who were screened at high falls risk using a large provincial database, and to determine the characteristics associated with being screened at ...

    Authors: Nooshin K. Rotondi, Dorcas E. Beaton, Rebeka Sujic, Earl Bogoch, Taucha Inrig, Denise Linton, Jennifer Weldon, Ravi Jain and Joanna E. M. Sale

    Citation: BMC Musculoskeletal Disorders 2020 21:372

    Content type: Research article

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  18. The purpose of this study was to determine the prevalence and characteristics of ligamentous knee injuries and to compare patient demographics, associated injuries and hospital stay to pedestrians who did not ...

    Authors: R. Garrett Steinmetz, Matthew McDonald, Shaun Tkach, John Hamilton, Gregory Heigle, Kimberly Hollabaugh, David Teague and Douglas Rowles

    Citation: BMC Musculoskeletal Disorders 2020 21:369

    Content type: Research article

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  19. Young adulthood is a sensitive period of life where development of musculoskeletal neck pain may be established and impact future health. The objective of this systematic review was to investigate risk factors...

    Authors: Henriette Jahre, Margreth Grotle, Kaja Smedbråten, Kate M. Dunn and Britt Elin Øiestad

    Citation: BMC Musculoskeletal Disorders 2020 21:366

    Content type: Research article

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  20. There are no recent studies on the frequency of paediatric lower extremity fractures in Germany. The aims of this study were to report fracture rates of paediatric lower extremity fractures treated in German h...

    Authors: Christoph Emanuel Gonser, Christian Bahrs, Philipp Hemmann and Daniel Körner

    Citation: BMC Musculoskeletal Disorders 2020 21:357

    Content type: Research article

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  21. Running is one of the most popular sports worldwide. Despite low back pain (LBP) represents the most common musculoskeletal disorder in population and in sports, there is currently sparse evidence about preval...

    Authors: Filippo Maselli, Lorenzo Storari, Valerio Barbari, Andrea Colombi, Andrea Turolla, Silvia Gianola, Giacomo Rossettini and Marco Testa

    Citation: BMC Musculoskeletal Disorders 2020 21:343

    Content type: Research article

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  22. Concerning the high prevalence of anxiety disorders and joint hypermobility in children and the lack of related studies in this age group, we aimed to assess the association of hypermobility with anxiety disor...

    Authors: Vadood Javadi Parvaneh, Shadialsadat Modaress, Ghazal Zahed, Khosro Rahmani and Reza Shiari

    Citation: BMC Musculoskeletal Disorders 2020 21:337

    Content type: Research article

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  23. Pressure ulcers (PU), one of the common challenging public health problems affecting patient with spinal cord injury. PUs occurs over bony areas of the body where pressure and tissue distortion is greatest. It...

    Authors: Wondimeneh Shibabaw Shiferaw, Tadesse Yirga Akalu, Henok Mulugeta and Yared Asmare Aynalem

    Citation: BMC Musculoskeletal Disorders 2020 21:334

    Content type: Research article

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  24. Osteoarthritis is generally a slowly progressive disorder. However, at least 1 in 7 people with incident knee osteoarthritis develop an abrupt progression to advanced-stage radiographic disease, many within 12...

    Authors: Jeffrey B. Driban, Matthew S. Harkey, Mary F. Barbe, Robert J. Ward, James W. MacKay, Julie E. Davis, Bing Lu, Lori Lyn Price, Charles B. Eaton, Grace H. Lo and Timothy E. McAlindon

    Citation: BMC Musculoskeletal Disorders 2020 21:332

    Content type: Review

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  25. Several studies have been performed to investigate association between IL-6 174G/C (rs1800795) and 572C/G (rs1800796) gene polymorphisms and osteoporosis predisposition. However, the results were conflicting. ...

    Authors: Bin Chen and Hong-zhuo Li

    Citation: BMC Musculoskeletal Disorders 2020 21:330

    Content type: Research article

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  26. With increasing number of patients undergoing spine surgery, the spinal epidural hemorrhage (SEH) has become a growing concern. However, current studies on SEH rely on case reports or observations from a singl...

    Authors: Ji Hyun Park, Sunny Park and Soo An Choi

    Citation: BMC Musculoskeletal Disorders 2020 21:324

    Content type: Research article

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  27. Musculoskeletal and sleep disorders have been reported to be very common among health care and hospital workers and particularly nurses. They are assumed or found to be a result of psychological stress and/or ...

    Authors: Oliver Hämmig

    Citation: BMC Musculoskeletal Disorders 2020 21:319

    Content type: Research article

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  28. Nurses in Africa are arguably the most important frontline healthcare workers available in most healthcare facilities, performing a broad range of tasks. Such tasks are considerably presumed in the causation o...

    Authors: Ayele Semachew Kasa, Yinager Workineh, Emiru Ayalew and Worku Animaw Temesgen

    Citation: BMC Musculoskeletal Disorders 2020 21:310

    Content type: Research article

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  29. Chronic spinal pain is prevalent, expensive and long-lasting. Several provider-based nonpharmacologic therapies have now been recommended for chronic low-back pain (CLBP) and chronic neck pain (CNP). However, ...

    Authors: Patricia M. Herman, Sarah E. Edgington, Eric L. Hurwitz and Ian D. Coulter

    Citation: BMC Musculoskeletal Disorders 2020 21:298

    Content type: Research article

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  30. Schmorls node (SN) are mostly asymptomatic and incidental findings on MRI. However, sometimes they present like acute onset low back pain or acute exacerbation of chronic back pain after minor trauma.

    Authors: Hyeun Sung Kim, Harshavardhan Dilip Raorane, Sagar Bhupendra Sharma, Pang Hung Wu and Il-Tae Jang

    Citation: BMC Musculoskeletal Disorders 2020 21:280

    Content type: Case report

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  31. Delirium is a well-known complication following surgery, especially with the increasing age of patients undergoing surgery. The increasing demands resulting from a prolonged healthy life expectancy has resulte...

    Authors: Eiji Kijima, Tomohiro Kayama, Mitsuru Saito, Daisaburo Kurosaka, Ryo Ikeda, Hiroteru Hayashi, Daisuke Kubota, Takashi Hyakutake and Keishi Marumo

    Citation: BMC Musculoskeletal Disorders 2020 21:279

    Content type: Research article

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  32. Benign joint hypermobility syndrome (BJHS) is one of the most common hereditary connective tissue disorders in children in which autonomic nervous system involvement has been reported. This study aimed to eval...

    Authors: Vadood Javadi Parvaneh, Hoda Shahvaladi, Khosro Rahmani, Sara Javdani Yekta, Fatemeh Abdollah Gorji, Reza Shiari and Fahimeh Abdollahimajd

    Citation: BMC Musculoskeletal Disorders 2020 21:268

    Content type: Research article

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  33. Health-related quality of life (HRQoL) is defined as the patient’s perception of their health status. HRQoL can be modified by illnesses, treatments or social and health policies. Chronic musculoskeletal pain ...

    Authors: Maria Jesus Mena-Iturriaga, Manuel Vicente Mauri-Stecca, Phillip S. Sizer and Jaime Leppe

    Citation: BMC Musculoskeletal Disorders 2020 21:262

    Content type: Research article

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  34. Physical activity is associated with positive health effects, but individuals with neuromuscular disease (NMD) may experience constraints being physically active. There is a gap in the literature on the activi...

    Authors: Aristomo Andries, Marleen R. van Walsem and Jan C. Frich

    Citation: BMC Musculoskeletal Disorders 2020 21:235

    Content type: Research article

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  35. To conduct a cross-cultural adaptation and validation of the Core Outcome Measures Index (COMI) in the Slovenian language, for use in patients with low back pain.

    Authors: Matevž Topolovec, David Vozlič, Nejc Plohl, Rok Vengust, Miha Vodičar and Anne Frances Mannion

    Citation: BMC Musculoskeletal Disorders 2020 21:232

    Content type: Research article

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  36. Low back pain (LBP) is a common health problem experienced after natural disasters. LBP is often concurrent with other musculoskeletal pain; however, the effects of preexisting musculoskeletal pain on the deve...

    Authors: Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Tadahisa Takahashi, Jun Iwatsu, Ichiro Tsuji and Eiji Itoi

    Citation: BMC Musculoskeletal Disorders 2020 21:227

    Content type: Research article

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  37. Femoroacetabular impingement (FAI) is an important cause of hip pain in young and active individuals and occurs as a result of size and shape mismatch between the femoral head and acetabulum. Open physes in ch...

    Authors: Axel Öhlin, Nicole Simunovic, Andrew Duong and Olufemi R. Ayeni

    Citation: BMC Musculoskeletal Disorders 2020 21:221

    Content type: Study protocol

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  38. Age-related sarcopenia is a serious global health issue in elderly individuals and for the community as it induces disability and significant economic burden. The purpose of the study is to understand the fact...

    Authors: Ailin Bian, Yue Ma, Xinzi Zhou, Ying Guo, Wenyi Wang, Yiran Zhang and Xiaofei Wang

    Citation: BMC Musculoskeletal Disorders 2020 21:214

    Content type: Research article

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  39. Axial spondyloarthritis (axSpA) frequently presents during working age and therefore impacts work participation. Biologic therapies have demonstrated a positive impact on work-related outcomes in clinical tria...

    Authors: Tom Nadin, Dinny Wallis, Christopher R. Holroyd, Stefania D’Angelo, Karen Walker-Bone and Christopher J. Edwards

    Citation: BMC Musculoskeletal Disorders 2020 21:209

    Content type: Research article

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  40. Muscle quality (i.e., the expression of muscle function per unit of muscle mass) has been proposed as a clinically-relevant measure to detect individuals at risk of functional incapacity. Individuals with obes...

    Authors: Pedro L. Valenzuela, Nicola A. Maffiuletti, Gabriella Tringali, Alessandra De Col and Alessandro Sartorio

    Citation: BMC Musculoskeletal Disorders 2020 21:200

    Content type: Research article

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  41. In an ageing population, pain, frailty and disability frequently coexist across a wide range of musculoskeletal diagnoses, but their associations remain incompletely understood. The Investigating Musculoskelet...

    Authors: Bonnie Millar, Daniel F. McWilliams, Abhishek Abhishek, Kehinde Akin-Akinyosoye, Dorothee P. Auer, Victoria Chapman, Michael Doherty, Eamonn Ferguson, John R. F. Gladman, Paul Greenhaff, Joanne Stocks, Ana M. Valdes and David A. Walsh

    Citation: BMC Musculoskeletal Disorders 2020 21:182

    Content type: Study protocol

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  42. Cervical radiculopathy is usually caused by disc herniation or spondylosis. The prognosis is expected to be good in most patients, but there is limited scientific evidence on the indications for nonsurgical an...

    Authors: Mirad Taso, Jon Håvard Sommernes, Frode Kolstad, Jarle Sundseth, Siri Bjorland, Are Hugo Pripp, John Anker Zwart and Jens Ivar Brox

    Citation: BMC Musculoskeletal Disorders 2020 21:171

    Content type: Study protocol

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  43. The purpose of this study was to determine whether a specific threshold per lifting movement, the accumulation above which best predicts lumbar disk protrusion, exists or the total lifting load should be consi...

    Authors: Isabella Y.-J. Hung, Tiffany T.-F. Shih, Bang-Bin Chen, Saou-Hsing Liou, Ing-Kang Ho and Yue Leon Guo

    Citation: BMC Musculoskeletal Disorders 2020 21:169

    Content type: Research article

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  44. Currently used performance measures for discrimination were not informative to determine the clinical benefit of predictor variables. The purpose was to evaluate if a former relevant predictor, kinesiophobia, ...

    Authors: A. M. Panken, J. B. Staal and M. W. Heymans

    Citation: BMC Musculoskeletal Disorders 2020 21:163

    Content type: Research article

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  45. MRI scanning has revolutionized the clinical diagnosis of lumbar spinal stenosis (LSS). However, there is currently no consensus as to how best to classify MRI findings which has hampered the development of ro...

    Authors: Yuyu Ishimoto, Amir Jamaludin, Cyrus Cooper, Karen Walker-Bone, Hiroshi Yamada, Hiroshi Hashizume, Hiroyuki Oka, Sakae Tanaka, Noriko Yoshimura, Munehito Yoshida, Jill Urban, Timor Kadir and Jeremy Fairbank

    Citation: BMC Musculoskeletal Disorders 2020 21:158

    Content type: Research article

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  46. Sonographers have reported a high occurrence of musculoskeletal pain for more than 25 years. Assessments of occupational risk factors have previously been based on cross-sectional surveys. The aim of this long...

    Authors: Jenny Gremark Simonsen, Anna Axmon, Catarina Nordander and Inger Arvidsson

    Citation: BMC Musculoskeletal Disorders 2020 21:156

    Content type: Research article

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  47. One in three women and one in five men are expected to experience a minimal-trauma-fracture after the age of 50-years, which increases the risk of subsequent fracture. Importantly, timely diagnosis and optimal...

    Authors: Steven A. Frost, Ayano Kelly, Julia Gaudin, Lynette Mc Evoy, Carol Wilson, Lynda Marov, Carlos El Haddad, Jacqueline Center, John A. Eisman, Tuan V. Nguyen and Geraldine Hassett

    Citation: BMC Musculoskeletal Disorders 2020 21:133

    Content type: Research article

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  48. Musculoskeletal injuries (MSK-I) are a serious problem in sports medicine. Modifiable and non-modifiable factors are associated with susceptibility to these injuries. Thus, the aim of this study was to describ...

    Authors: Rodrigo Araújo Goes, Lucas Rafael Lopes, Victor Rodrigues Amaral Cossich, Vitor Almeida Ribeiro de Miranda, Olívia Nogueira Coelho, Ricardo do Carmo Bastos, Letícia Aparecida Marincolo Domenis, João Antonio Matheus Guimarães, João Alves Grangeiro-Neto and Jamila Alessandra Perini

    Citation: BMC Musculoskeletal Disorders 2020 21:122

    Content type: Research article

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  49. Patients with chondrocalcinosis may suffer from a series of symptoms resembling acute gouty arthritis or septic arthritis, but the aetiology and pathogenesis of chondrocalcinosis have not been fully elucidated...

    Authors: Hongyi He, Yilun Wang, Zidan Yang, Xiang Ding, Tuo Yang, Guanghua Lei, Hui Li and Dongxing Xie

    Citation: BMC Musculoskeletal Disorders 2020 21:97

    Content type: Research article

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  50. Diffuse idiopathic skeletal hyperostosis (DISH) is characterized by the ossification of vertebral bodies and peripheral entheses. However, variations in sacroiliac (SI) joint change in patients with DISH have ...

    Authors: Yasuhito Yahara, Taketoshi Yasuda, Yoshiharu Kawaguchi, Kayo Suzuki, Shoji Seki, Miho Kondo, Hiroto Makino, Katsuhiko Kamei, Masahiko Kanamori and Tomoatsu Kimura

    Citation: BMC Musculoskeletal Disorders 2020 21:93

    Content type: Research article

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