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Epidemiology of musculoskeletal disorders

Section edited by Anita Wluka

This section concerns all aspects of the epidemiology of musculoskeletal disorders including but not limited to: cohort studies, genetic association studies, and prevalence studies.

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  1. Content type: Research article

    Osteoarthritis (OA) is associated with worsening physical function and a high prevalence of comorbid health conditions. In particular, cardiovascular disease (CVD) risk is higher in individuals with OA than th...

    Authors: Michela Corsi, Carolina Alvarez, Leigh F. Callahan, Rebecca J. Cleveland, Yvonne M. Golightly, Joanne M. Jordan, Amanda E. Nelson, Jordan Renner, Allen Tsai and Kelli D. Allen

    Citation: BMC Musculoskeletal Disorders 2018 19:393

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  2. Content type: Research article

    Although “non-specific” in 90% of cases, low back pain (LBP) is often treated as an independent entity, even though comorbidities are commonly associated with it. There is evidence that some LBP may be related...

    Authors: Shanthi Ramanathan, Peter Hibbert, Louise Wiles, Christopher G. Maher and William Runciman

    Citation: BMC Musculoskeletal Disorders 2018 19:391

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  3. Content type: Research article

    Previous research suggests that sleep problems may be an important predictor for chronic widespread pain (CWP). With this study we investigated both sleep problems and fatigue as predictors for the onset of CW...

    Authors: Katarina Aili, Maria Andersson, Ann Bremander, Emma Haglund, Ingrid Larsson and Stefan Bergman

    Citation: BMC Musculoskeletal Disorders 2018 19:390

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  4. Content type: Research article

    Few reports have explored the extent to which physical activity is affected by pain severity in knee osteoarthritis (KOA) patients. We used national representative data to investigate the physical activity of ...

    Authors: Hye-Young Shim, Mira Park, Hee-June Kim, Hee-Soo Kyung and Ji-Yeon Shin

    Citation: BMC Musculoskeletal Disorders 2018 19:380

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  5. Content type: Research article

    Intervertebral disk degeneration (IDD) is a common musculoskeletal disease associated with genetic factors. COL9A3 gene encodes the α3 (IX) chain of type IX collagen that is part of the interior structure of the ...

    Authors: Donghua Huang, Xiangyu Deng, Kaige Ma, Fashuai Wu, Deyao Shi, Hang Liang, Sheng Chen and Zengwu Shao

    Citation: BMC Musculoskeletal Disorders 2018 19:381

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  6. Content type: Research article

    Musculoskeletal injuries are the main cause of premature discharge from military service and can sometimes lead to permanent disabilities. Some intrinsic risk factors are well discussed in the literature. Howe...

    Authors: Mauro A. S. Melloni, Josiel De Almeida Ávila, Mauro Alexandre Páscoa, Camila Justino De Oliveira Barbeta, Vagner Xavier Cirolini, Ezequiel M. Gonçalves and Gil Guerra-Júnior

    Citation: BMC Musculoskeletal Disorders 2018 19:377

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  7. Content type: Study protocol

    Overuse injuries (OI) are common in elite athletics. Previous studies have had athletes self-report injuries rather than having a medical professional provide a clear diagnosis. This might be a major reason fo...

    Authors: Andreas Lundberg Zachrisson, Pia Desai, Jon Karlsson, Elias Johanesson and Stefan Grau

    Citation: BMC Musculoskeletal Disorders 2018 19:370

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  8. Content type: Research article

    Hip fractures are a major worldwide public health problem and includes two main types of fractures: the intracapsular (cervical) and the extracapsular (trochanteric and subtrochanteric) fractures. The aim of t...

    Authors: Leif Mattisson, Alicja Bojan and Anders Enocson

    Citation: BMC Musculoskeletal Disorders 2018 19:369

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  9. Content type: Research article

    Poor general health predicts the transition to chronic back pain (CBP), but the role of specific medical conditions in the development of CBP is unclear. The study aim was to examine the association of medical...

    Authors: Pradeep Suri, Edward J. Boyko, Sean D. Rundell, Nicholas L. Smith and Jack Goldberg

    Citation: BMC Musculoskeletal Disorders 2018 19:362

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  10. Content type: Research article

    Approximately one in five patients undergoing knee replacement surgery experience chronic pain after their operation, which can negatively impact on their quality of life. In order to develop and evaluate inte...

    Authors: Rafael Pinedo-Villanueva, Sara Khalid, Vikki Wylde, Rachael Gooberman-Hill, Anushka Soni and Andrew Judge

    Citation: BMC Musculoskeletal Disorders 2018 19:354

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  11. Content type: Research article

    The purpose of this study was to estimate the prevalence of postinjection paralysis (PIP) and gluteal fibrosis (GF) among children treated in a rural Ugandan Hospital.

    Authors: Kristin Alves, Norgrove Penny, John Ekure, Robert Olupot, Olive Kobusingye, Jeffrey N. Katz and Coleen S. Sabatini

    Citation: BMC Musculoskeletal Disorders 2018 19:343

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  12. Content type: Research article

    The Pain Coping Skills Training for African Americans with OsteoaRTthritis (STAART) trial is examining the effectiveness of a culturally enhanced pain coping skills training (CST) program for African Americans wi...

    Authors: Kelli D. Allen, Liubov Arbeeva, Crystal W. Cené, Cynthia J. Coffman, Kimberlea F. Grimm, Erin Haley, Francis J. Keefe, Caroline T. Nagle, Eugene Z. Oddone, Tamara J. Somers, Yashika Watkins and Lisa C. Campbell

    Citation: BMC Musculoskeletal Disorders 2018 19:337

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  13. Content type: Research article

    Cervical spondylosis adversely affects life quality for its heavy disease burden. The report on the community-based prevalence and associated factors of cervical spondylosis is rare, especially in Chinese popu...

    Authors: Yanwei Lv, Wei Tian, Dafang Chen, Yajun Liu, Lifang Wang and Fangfang Duan

    Citation: BMC Musculoskeletal Disorders 2018 19:325

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  14. Content type: Research article

    Big data research is important for studying uncommon diseases in real-world settings. Most big data studies in axial spondyloarthritis (axSpA) have been limited to populations identified with billing codes for...

    Authors: Jessica A. Walsh, Shaobo Pei, Gopi K. Penmetsa, Jianwei Leng, Grant W. Cannon, Daniel O. Clegg and Brian C. Sauer

    Citation: BMC Musculoskeletal Disorders 2018 19:317

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  15. Content type: Research article

    While low back pain is a common presenting complaint in the emergency department, current estimates from Canada are limited. Furthermore, existing estimates do not clearly define low back pain. As such, our ma...

    Authors: Jordan Edwards, Jill Hayden, Mark Asbridge and Kirk Magee

    Citation: BMC Musculoskeletal Disorders 2018 19:306

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  16. Content type: Research article

    This study aimed to a) describe the prevalence of knee and hip osteoarthritis risk factors in a population of 29–59 year old individuals, b) estimate the association between persistent knee/hip pain and osteoa...

    Authors: Joyce A. C. van Tunen, George Peat, Alessio Bricca, Lars B. Larsen, Jens Søndergaard, Trine Thilsing, Ewa M. Roos and Jonas B. Thorlund

    Citation: BMC Musculoskeletal Disorders 2018 19:300

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  17. Content type: Research article

    There have been fewer improvements in the clinical outcomes of adolescent and young adult (AYA) patients with cancer than for children and older adults, possibly because fewer studies focus on patients in this...

    Authors: Takashi Fukushima, Koichi Ogura, Toru Akiyama, Katsushi Takeshita and Akira Kawai

    Citation: BMC Musculoskeletal Disorders 2018 19:297

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  18. Content type: Research article

    Osteoarthritis (OA) is a leading cause of pain and disability. NICE OA guidelines (2008) recommend that patients with OA should be offered core treatments in primary care. Assessments of OA management have ide...

    Authors: Emma Louise Healey, Ebenezer K. Afolabi, Martyn Lewis, John J. Edwards, Kelvin P. Jordan, Andrew Finney, Clare Jinks, Elaine M. Hay and Krysia S. Dziedzic

    Citation: BMC Musculoskeletal Disorders 2018 19:295

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  19. Content type: Research article

    To use Magnetic Resonance Imaging (MRI) to characterize the severity, location, prevalence, and demographics of shoulder injuries in athletes at the Rio de Janeiro 2016 Summer Olympic Games.

    Authors: Akira M. Murakami, Andrew J. Kompel, Lars Engebretsen, Xinning Li, Bruce B. Forster, Michel D. Crema, Daichi Hayashi, Mohamed Jarraya, Frank W. Roemer and Ali Guermazi

    Citation: BMC Musculoskeletal Disorders 2018 19:296

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  20. Content type: Research article

    Musculoskeletal (MSK) conditions are common and the biggest global cause of physical disability. The objective of the current study was to estimate the population prevalence of MSK-related pain using a standar...

    Authors: D. G. Hoy, T. Raikoti, E. Smith, A. Tuzakana, T. Gill, K. Matikarai, J. Tako, A. Jorari, F. Blyth, A. Pitaboe, R. Buchbinder, I. Kalauma, P. Brooks, C. Lepers, A. Woolf, A. Briggs…

    Citation: BMC Musculoskeletal Disorders 2018 19:292

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  21. Content type: Research article

    Lower extremity joint contractures have negative effects on gait in children with Duchenne muscular dystrophy (DMD). Thus, contracture prevention is essential for maintaining a patient’s functional ability and...

    Authors: Young-Ah Choi, Seong-Min Chun, Yale Kim and Hyung-Ik Shin

    Citation: BMC Musculoskeletal Disorders 2018 19:287

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  22. Content type: Research article

    Developed in the Norway, the Measure of Activity Performance of the Hand (MAP-Hand) assesses 18 activities performed using the hands. It was developed for people with rheumatoid arthritis (RA) using patient ge...

    Authors: Yeliz Prior, Alan Tennant, Sarah Tyson, Ingvild Kjeken and Alison Hammond

    Citation: BMC Musculoskeletal Disorders 2018 19:275

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  23. Content type: Research article

    Ethiopian school children often carry school supplies in heavy school bags and encounter limited school facilities. This stresses their vulnerable musculoskeletal system and may result in experiencing musculos...

    Authors: Manayesh Delele, Balamurugan Janakiraman, Abey Bekele Abebe, Ararso Tafese and Alexander T. M. van de Water

    Citation: BMC Musculoskeletal Disorders 2018 19:276

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  24. Content type: Research article

    Congenital limb deficiency is a rare and intractable disease, which impairs both function and appearance of the limbs. To establish adequate medical care, it is necessary to reveal the actual conditions and pr...

    Authors: Hiroshi Mano, Sayaka Fujiwara, Kazuyuki Takamura, Hiroshi Kitoh, Shinichiro Takayama, Tsutomu Ogata, Shuji Hashimoto and Nobuhiko Haga

    Citation: BMC Musculoskeletal Disorders 2018 19:262

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  25. Content type: Research article

    Calcaneal apophysitis is a common clinical entity affecting children and adolescents. It is also known as Sever’s disease. Heel pain without a recent trauma is the primary manifestation. There are limited stud...

    Authors: H. H. Ceylan and B. Caypinar

    Citation: BMC Musculoskeletal Disorders 2018 19:267

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  26. Content type: Research article

    Obesity and musculoskeletal pain are strongly related, but there is emerging evidence that body fat, not body weight, may be a better indicator of risk. There is, therefore, a need to determine if body fat is ...

    Authors: Tom P. Walsh, John B. Arnold, Angela M. Evans, Alison Yaxley, Raechel A. Damarell and E. Michael Shanahan

    Citation: BMC Musculoskeletal Disorders 2018 19:233

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  27. Content type: Study protocol

    Bisphosphonates are a class of drugs that slow bone loss and are a promising candidate to treat knee osteoarthritis (OA) patients. In a pilot study, we demonstrated that zoledronic acid reduced knee pain and s...

    Authors: Dawn Aitken, Laura L. Laslett, Guoqi Cai, Catherine Hill, Lyn March, Anita E. Wluka, Yuanyuan Wang, Leigh Blizzard, Flavia Cicuttini and Graeme Jones

    Citation: BMC Musculoskeletal Disorders 2018 19:217

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  28. Content type: Research article

    Deep vein thrombosis is a well-known complication of fracture occurrence, lower limb surgery and periods of prolonged immobilisation. Its incidence can be increased even more in specific cases with metastatic ...

    Authors: Mihail-Lazar Mioc, Radu Prejbeanu, Dinu Vermesan, Horia Haragus, Marius Niculescu, Daniel Laurentiu Pop, Andrei Dan Balanescu, Daniel Malita and Bogdan Deleanu

    Citation: BMC Musculoskeletal Disorders 2018 19:213

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  29. Content type: Research article

    Not much is known about the characteristics, course and prognosis of complaints of arm, neck and/or shoulder that have not been caused by a trauma or systemic disease (CANS), in a screened population. This stu...

    Authors: Vivian E. J. Bruls, Nicole W. H. Jansen, Sander M. J. van Kuijk, IJmert Kant and Caroline H. G. Bastiaenen

    Citation: BMC Musculoskeletal Disorders 2018 19:208

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  30. Content type: Research article

    Hip fracture patients in general are elderly and they often have comorbidities that may necessitate anticoagulation treatment, such as warfarin. It has been emphasized that these patients benefit from surgery ...

    Authors: Leif Mattisson, Lasse J. Lapidus and Anders Enocson

    Citation: BMC Musculoskeletal Disorders 2018 19:203

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  31. Content type: Research article

    Low back pain (LBP) remains a common health problem and one of the most prevalent musculoskeletal conditions found among developed and developing nations. The following paper reports on an updated search of th...

    Authors: Linzette Deidrè Morris, Kurt John Daniels, Bhaswati Ganguli and Quinette Abegail Louw

    Citation: BMC Musculoskeletal Disorders 2018 19:196

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  32. Content type: Research article

    There is consistent evidence from observational studies of an association between occupational lifting and carrying of heavy loads and the diagnosis of hip osteoarthritis. However, due to the heterogeneity of ...

    Authors: Andreas Seidler, Laura Lüben, Janice Hegewald, Ulrich Bolm-Audorff, Annekatrin Bergmann, Falk Liebers, Christina Ramdohr, Karla Romero Starke, Alice Freiberg and Susanne Unverzagt

    Citation: BMC Musculoskeletal Disorders 2018 19:182

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  33. Content type: Research article

    Computed tomography (CT) analyses have reported that the prevalence of diffuse idiopathic skeletal hyperostosis (DISH) in Japan is 8.7–27.1%. However, these data were obtained using chest-abdominal CT, and no ...

    Authors: Akihiko Hiyama, Hiroyuki Katoh, Daisuke Sakai, Masato Sato, Masahiro Tanaka and Masahiko Watanabe

    Citation: BMC Musculoskeletal Disorders 2018 19:178

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  34. Content type: Research article

    The relationships between radiographic hallux valgus (HV) and various physical functions independent of knee osteoarthritis (KOA) were examined among residents of a mountain village in Japan.

    Authors: Akinobu Nishimura, Naoya Ito, Shigeto Nakazora, Ko Kato, Toru Ogura and Akihiro Sudo

    Citation: BMC Musculoskeletal Disorders 2018 19:174

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  35. Content type: Research article

    Previous studies that have described the prevalence of patellofemoral pain (PFP) have been limited to samples of military personnel or sporting populations, and convincing data in the general Chinese populatio...

    Authors: Xingquan Xu, Chen Yao, Rui Wu, Wenjin Yan, Yao Yao, Kai Song, Qing Jiang and Dongquan Shi

    Citation: BMC Musculoskeletal Disorders 2018 19:165

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  36. Content type: Research article

    Nonspecific low back pain is characterized by a wide range of possible triggering and conserving factors, and initial screening needs to scope widely with multilevel addressment of possible factors contributin...

    Authors: Monica Unsgaard-Tøndel, Ingunn Gunnes Kregnes, Tom I. L. Nilsen, Gunn Hege Marchand and Torunn Askim

    Citation: BMC Musculoskeletal Disorders 2018 19:166

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  37. Content type: Research article

    Cartilage calcification (CC) is associated with osteoarthritis (OA) in weight-bearing joints, such as the hip and the knee. However, little is known about the impact of CC and degeneration on other weight-bear...

    Authors: Jan Hubert, Lukas Weiser, Sandra Hischke, Annemarie Uhlig, Tim Rolvien, Tobias Schmidt, Sebastian Karl Butscheidt, Klaus Püschel, Wolfgang Lehmann, Frank Timo Beil and Thelonius Hawellek

    Citation: BMC Musculoskeletal Disorders 2018 19:169

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  38. Content type: Research article

    A stress fracture (SF) is a highly debilitating injury commonly experienced in United States Army Basic Combat Training (BCT). Body fat (BF) may be associated with this injury but previous investigations (in a...

    Authors: Joseph J. Knapik, Marilyn A. Sharp and Scott J. Montain

    Citation: BMC Musculoskeletal Disorders 2018 19:161

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  39. Content type: Research article

    The physical and biochemical factors responsible for cervical disc degeneration, and resulting in various spinal disorders, remain unclear. This study aimed to evaluate the correlation between cervical spinal ...

    Authors: Kanichiro Wada, Toshihiro Tanaka, Gentaro Kumagai, Hitoshi Kudo, Toru Asari, Daisuke Chiba, Seiya Ota, Keita Kamei, On Takeda, Shigeyuki Nakaji and Yasuyuki Ishibashi

    Citation: BMC Musculoskeletal Disorders 2018 19:153

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  40. Content type: Research article

    Clinical evidence shows knee arthroscopy has little benefit for degenerative conditions and considerable variation in the incidence of knee arthroscopy in Australia has been identified. This study aimed to eva...

    Authors: H. Y. Chen, I. A. Harris, K. Sutherland and J-F. Levesque

    Citation: BMC Musculoskeletal Disorders 2018 19:148

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  41. Content type: Research article

    The PACE Plus trial was a multi-center, double-blinded, superiority randomized controlled trial (RCT) conducted in patients from Dutch general practice to investigate the efficacy of paracetamol and NSAIDs in ...

    Authors: M. Schreijenberg, P. A. J. Luijsterburg, Y. D. M. Van Trier, D. Rizopoulos, M. A. Koopmanschap, L. Voogt, C. G. Maher and B. W. Koes

    Citation: BMC Musculoskeletal Disorders 2018 19:146

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  42. Content type: Research article

    It was reported that Fas (rs1800682, rs2234767) and FasL (rs5030772, rs763110) gene polymorphism might be related to the risk of musculoskeletal degenerative diseases (MSDD), such as osteoarthritis (OA), inter...

    Authors: Donghua Huang, Jinrong Xiao, Xiangyu Deng, Kaige Ma, Hang Liang, Deyao Shi, Fashuai Wu and Zengwu Shao

    Citation: BMC Musculoskeletal Disorders 2018 19:137

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  43. Content type: Research article

    The aim of this study was to investigate the prospective association between insomnia and risk of chronic musculoskeletal complaints (CMSC) and chronic widespread musculoskeletal complaints (CWMSC). A second a...

    Authors: B. L. Uhlig, T. Sand, T. I. Nilsen, P. J. Mork and K. Hagen

    Citation: BMC Musculoskeletal Disorders 2018 19:128

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  44. Content type: Research article

    Low back pain is a common health complaint resulting in substantial economic burden. Each year, upwards of 20 randomised controlled trials (RCTs) evaluating interventions for non-specific low back pain are pub...

    Authors: Pål André Amundsen, David W. Evans, Dévan Rajendran, Philip Bright, Tom Bjørkli, Sandra Eldridge, Rachelle Buchbinder, Martin Underwood and Robert Froud

    Citation: BMC Musculoskeletal Disorders 2018 19:113

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  45. Content type: Research article

    Episodes of low back pain (LBP) are very common among workers. A number of occupational risk factors have been shown to increase the risk for LBP. One of these risk factors is exposure to whole body vibration,...

    Authors: Oren Zack, Regina Levin, Ayala Krakov, Aharon S. Finestone and Shlomo Moshe

    Citation: BMC Musculoskeletal Disorders 2018 19:110

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  46. Content type: Research article

    Differences between staged bilateral total knee replacement (TKR) and simultaneous bilateral TKR have been investigated, but few studies have investigated differences in the functional improvements resulting f...

    Authors: Yu-Hao Huang, Chin Lin, Jia-Hwa Yang, Leou-Chyr Lin, Chih-Yuan Mou, Kwo-Tsao Chiang, Man-Gang Lee, Hsien-Feng Chang, Hsueh-Lu Chang, Wen Su, Shih-Jen Yeh, Hung Chang, Chih-Chien Wang and Sui-Lung Su

    Citation: BMC Musculoskeletal Disorders 2018 19:87

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  47. Content type: Research article

    Being at risk for malnutrition can be observed among hospitalized patients of all medical specialties. There are only few studies in arthroplasty dealing with defining and assessing malnutrition as such a pote...

    Authors: Christoph Ihle, Christoph Weiß, Gunnar Blumenstock, Ulrich Stöckle, Björn Gunnar Ochs, Christian Bahrs, Andreas Nüssler and Anna Janine Schreiner

    Citation: BMC Musculoskeletal Disorders 2018 19:83

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  48. Content type: Research article

    Knee osteoarthritis (OA) is the most common form of arthritis affecting the elderly. Understanding the risk factors for knee OA has been derived from cross sectional studies. There have been few longitudinal s...

    Authors: Jong Jin Yoo, Dong Hyun Kim and Hyun Ah Kim

    Citation: BMC Musculoskeletal Disorders 2018 19:80

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  49. Content type: Research article

    Few studies have examined patterns of specific sleep problems among individuals with osteoarthritis (OA). The primary objective of this study was to examine prevalence of symptoms of insomnia and obstructive s...

    Authors: Shannon Stark Taylor, Jaime M. Hughes, Cynthia J. Coffman, Amy S. Jeffreys, Christi S. Ulmer, Eugene Z. Oddone, Hayden B. Bosworth, William S. Yancy Jr and Kelli D. Allen

    Citation: BMC Musculoskeletal Disorders 2018 19:79

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