Skip to main content

Clinical rheumatology and osteoporosis

This section concerns all aspects of research into osteoporosis and rheumatic diseases, where the primary focus relates specifically to a component(s) of the musculoskeletal system

Page 7 of 7

  1. Patient reported outcomes (PROs) are especially useful in assessing treatments for rheumatoid arthritis (RA) since they measure dimensions of health-related quality of life that cannot be captured using strict...

    Authors: Sang-Cheol Bae, Suk Chyn Gun, Chi Chiu Mok, Rezaul Khandker, Henk W Nab, Andrew S Koenig, Bonnie Vlahos, Ron Pedersen and Amitabh Singh

    Citation: BMC Musculoskeletal Disorders 2013 14:13

    Content type: Research article

    Published on:

  2. Until now the exact biochemical processes during healing of metaphyseal fractures of healthy and osteoporotic bone remain unclear. Especially the physiological time courses of 25(OH)D3 (Vitamin D) as well as PTH ...

    Authors: Christoph Wöfl, Sarah Englert, Arash A Moghaddam, Gerald Zimmermann, Gerhard Schmidt-Gayk, Bernd Höner, Aidan Hogan, Marcus Lehnhardt, Paul A Grützner and Leila Kolios

    Citation: BMC Musculoskeletal Disorders 2013 14:6

    Content type: Research article

    Published on:

    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2014 15:70

  3. Improper medication adherence is associated with increased morbidity, healthcare costs, and fracture risk among patients with osteoporosis. The objective of this study was to evaluate the healthcare utilizatio...

    Authors: Leslie Hazel-Fernandez, Anthony M Louder, Shonda A Foster, Claudia L Uribe and Russel T Burge

    Citation: BMC Musculoskeletal Disorders 2013 14:4

    Content type: Research article

    Published on:

  4. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a widely used patient reported outcome in osteoarthritis. An important, but frequently overlooked, aspect of validating health outc...

    Authors: Beth Pollard, Marie Johnston and Diane Dixon

    Citation: BMC Musculoskeletal Disorders 2012 13:265

    Content type: Research article

    Published on:

  5. The aim of the present study was to assess whether the efficacy of bisphosphonate treatment is influenced by PTH levels measured in newly diagnosed osteoporotic patients and to identify the threshold value, be...

    Authors: Gyöngyvér Kincse, József Varga, Péter Somogyi, Péter Szodoray, Péter Surányi and János Gaál

    Citation: BMC Musculoskeletal Disorders 2012 13:244

    Content type: Research article

    Published on:

  6. Gout is the commonest inflammatory arthritis affecting around 1.4% of adults in Europe. It is predominantly managed in primary care and classically affects the joints of the foot, particularly the first metata...

    Authors: Priyanka Chandratre, Christian Mallen, Jane Richardson, Keith Rome, Joanne Bailey, Rajvinder Gill, Samantha Hider, Jane Mason, Zoe Mayson, Sara Muller, Charlotte Purcell, Jennifer Titley, Simon Wathall, Irena Zwierska and Edward Roddy

    Citation: BMC Musculoskeletal Disorders 2012 13:219

    Content type: Study protocol

    Published on:

  7. Although item response theory (IRT) appears to be increasingly used within health care research in general, a comprehensive overview of the frequency and characteristics of IRT analyses within the rheumatic fi...

    Authors: Liseth Siemons, Peter M ten Klooster, Erik Taal, Cees AW Glas and Mart AFJ Van de Laar

    Citation: BMC Musculoskeletal Disorders 2012 13:216

    Content type: Research article

    Published on:

  8. Combinations of disease-modifying anti-rheumatic drugs (DMARDs) are increasingly used to control active rheumatoid arthritis (RA); however there is little information about patients’ perspectives, their expect...

    Authors: Heidi Lempp, Darija Hofmann, Stephani L Hatch and David L Scott

    Citation: BMC Musculoskeletal Disorders 2012 13:200

    Content type: Research article

    Published on:

  9. Self-management programmes (SMP) are recommended for patients with fibromyalgia. The purpose of this study was to evaluate effects of a one week multidisciplinary inpatient self-management programme on psychol...

    Authors: Bente Hamnes, Petter Mowinckel, Ingvild Kjeken and Kåre B Hagen

    Citation: BMC Musculoskeletal Disorders 2012 13:189

    Content type: Research article

    Published on:

  10. Although recent advances in knee osteoarthritis (OA) treatment and evaluation were achieved, to the best of our knowledge, few studies have evaluated the longitudinal effect of therapeutic modalities on the fu...

    Authors: Naryana Cristina Mascarin, Rodrigo Luiz Vancini, Marília dos Santos Andrade, Eduardo de Paiva Magalhães, Claudio Andre Barbosa de Lira and Ibsen Bellini Coimbra

    Citation: BMC Musculoskeletal Disorders 2012 13:182

    Content type: Research article

    Published on:

  11. For patients to effectively manage gout, they need to be aware of the impact of diet, alcohol use, and medications on their condition. We sought to examine patients’ knowledge and beliefs concerning gout and i...

    Authors: Leslie R Harrold, Kathleen M Mazor, Daniel Peterson, Nausheen Naz, Cassandra Firneno and Robert A Yood

    Citation: BMC Musculoskeletal Disorders 2012 13:180

    Content type: Research article

    Published on:

  12. Long term serum urate (SU) lowering to a target of <0.36 mmol/l (6 mg/dl) is recommended for effective gout management. However, many studies have reported low achievement of SU targets. The aim of this cross-...

    Authors: Nicola Dalbeth, Meaghan E House, Anne Horne, Keith J Petrie, Fiona M McQueen and William J Taylor

    Citation: BMC Musculoskeletal Disorders 2012 13:174

    Content type: Research article

    Published on:

  13. African Americans are twice as likely as Caucasians to develop gout, but they are less likely to be treated with urate-lowering therapy (ULT). Furthermore, African Americans typically present with more comorbi...

    Authors: Alvin F Wells, Patricia A MacDonald, Solomon Chefo and Robert L Jackson

    Citation: BMC Musculoskeletal Disorders 2012 13:15

    Content type: Research article

    Published on:

  14. It is still unclear when latent myofascial trigger points (MTrPs) develop during early life. This study is designed to investigate the mechanical pain sensitivity of deep tissues in children in order to see th...

    Authors: Ting-I Han, Chang-Zern Hong, Fang-Chuan Kuo, Yueh-Ling Hsieh, Li-Wei Chou and Mu-Jung Kao

    Citation: BMC Musculoskeletal Disorders 2012 13:13

    Content type: Research article

    Published on:

  15. Inflammation is the main cause of disease-associated muscle wasting. In a previous single blind study we have demonstrated improved recovery of muscle endurance following celecoxib treatment in hospitalized ge...

    Authors: Ingo Beyer, Ivan Bautmans, Rose Njemini, Christian Demanet, Pierre Bergmann and Tony Mets

    Citation: BMC Musculoskeletal Disorders 2011 12:292

    Content type: Research article

    Published on:

  16. FTY720 (Fingolimod) is a novel immunosuppressive drug investigated in clinical trials for organ transplantation and multiple sclerosis. It acts as a functional sphingosine-1-phosphate (S1P) receptor antagonist...

    Authors: Martin H Stradner, Hannes Angerer, Thomas Ortner, Florentine C Fuerst, Daniela Setznagl, Marie-Luise Kremser, Josef Hermann and Winfried B Graninger

    Citation: BMC Musculoskeletal Disorders 2011 12:279

    Content type: Research article

    Published on:

  17. Several symptom-relieving interventions have been shown to be efficacious among osteoarthritis (OA) patients with knee effusion; however, not every symptomatic knee OA patient has clinical effusion. Results ma...

    Authors: Nicole M Cattano, Jeffrey B Driban, Easwaran Balasubramanian, Mary F Barbe, Mamta Amin and Michael R Sitler

    Citation: BMC Musculoskeletal Disorders 2011 12:273

    Content type: Research article

    Published on:

  18. This multicenter, open-label, prospective, single cohort study evaluated the effectiveness and safety of adalimumab in a clinical setting reflecting the Canadian standard of care for the treatment of patients ...

    Authors: Boulos Haraoui, Alfred Cividino, Jacqueline Stewart, Benoît Guérette and Edward C Keystone

    Citation: BMC Musculoskeletal Disorders 2011 12:261

    Content type: Research article

    Published on:

  19. This work aimed to study the homing evidence and the reparative effect of mesenchymal stem cells (MSCs) in the healing process of induced osteoarthritis in experimental animal model (donkeys).

    Authors: Abir N Mokbel, Omar S El Tookhy, Ashraf A Shamaa, Laila A Rashed, Dina Sabry and Abeer M El Sayed

    Citation: BMC Musculoskeletal Disorders 2011 12:259

    Content type: Research article

    Published on:

  20. Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus int...

    Authors: Katja Bloecker, Martin Englund, Wolfgang Wirth, Martin Hudelmaier, Rainer Burgkart, Richard B Frobell and Felix Eckstein

    Citation: BMC Musculoskeletal Disorders 2011 12:248

    Content type: Research article

    Published on:

  21. Current treatments for osteoporosis are associated with various side effects and do not prevent the age-related decrease in osteoblast number. The objective of this study was to evaluate the effects of iQPR-H2O o...

    Authors: Chiming Lee, Meileng Cheong, Wentien Hsiao, Henyu Liu, Chingyu Tsai, Mingfu Wang, Chihhsiung Wu, Kwanghwa Chang, Gowlin Lam and Winping Deng

    Citation: BMC Musculoskeletal Disorders 2011 12:227

    Content type: Research article

    Published on:

  22. The efficacy and tolerability of 500-730 kDa sodium hyaluronate (Hyalgan®) for treatment of osteoarthritis (OA) pain has been established in clinical trials, but few data are available in the Asian population. We...

    Authors: Teng-Le Huang, Chi-Ching Chang, Chian-Her Lee, Shih-Ching Chen, Chien-Hung Lai and Ching-Lin Tsai

    Citation: BMC Musculoskeletal Disorders 2011 12:221

    Content type: Research article

    Published on:

  23. Pulsed electromagnetic fields (PEMF) stimulation has been used successfully to treat nonunion fractures and femoral head osteonecrosis, but relatively little is known about its effects on preventing steroid-in...

    Authors: Shuai Ding, Hao Peng, Hong-Song Fang, Jian-Lin Zhou and Zhe Wang

    Citation: BMC Musculoskeletal Disorders 2011 12:215

    Content type: Research article

    Published on:

  24. In the absence of head-to-head trials, indirect comparisons of randomized placebo-controlled trials may provide a viable option to assess relative efficacy. The purpose was to estimate the relative efficacy of...

    Authors: Robert B Hopkins, Ron Goeree, Eleanor Pullenayegum, Jonathan D Adachi, Alexandra Papaioannou, Feng Xie and Lehana Thabane

    Citation: BMC Musculoskeletal Disorders 2011 12:209

    Content type: Research article

    Published on:

  25. Maximal isometric quadriceps strength deficits have been widely reported in studies of knee osteoarthritis (OA), however little is known about the effect of osteoarthritis knee pain on submaximal quadriceps ne...

    Authors: Michael J Berger, David G Chess and Timothy J Doherty

    Citation: BMC Musculoskeletal Disorders 2011 12:199

    Content type: Research article

    Published on:

  26. Although viscosupplementation is an effective symptomatic treatment for knee osteoarthritis (OA), the effect of longer term administration on articular cartilage has not been fully explored. We examined the ef...

    Authors: Yuanyuan Wang, Stephen Hall, Fahad Hanna, Anita E Wluka, Gail Grant, Paul Marks, Marie Feletar and Flavia M Cicuttini

    Citation: BMC Musculoskeletal Disorders 2011 12:195

    Content type: Research article

    Published on:

  27. Osteoporosis is a major health problem worldwide, and is included in the WHO list of the top 10 major diseases. However, it is often undiagnosed until the first fracture occurs, due to inadequate patient educa...

    Authors: Leila Kolios, Caner Takur, Arash Moghaddam, Mirjam Hitzler, Heinrich Schmidt-Gayk, Arnold J Suda, Bernd Höner, Paul A Grützner and Christoph Wölfl

    Citation: BMC Musculoskeletal Disorders 2011 12:187

    Content type: Research article

    Published on:

  28. Monitoring osteoporosis therapy by measurement of bone turnover markers (BTMs) might detect non-compliance in an earlier stage of anti-osteoporosis treatment and improve persistence.

    Authors: Danielle A Eekman, Irene EM Bultink, Annemieke C Heijboer, Ben AC Dijkmans and Willem F Lems

    Citation: BMC Musculoskeletal Disorders 2011 12:167

    Content type: Research article

    Published on:

  29. Clinical analgesic trials typically report response as group mean results. However, research has shown that few patients are average and most have responses at the extremes. Moreover, group mean results do not...

    Authors: Paul M Peloso, Arnold Gammaitoni, Steven S Smugar, Hongwei Wang and Andrew R Moore

    Citation: BMC Musculoskeletal Disorders 2011 12:165

    Content type: Research article

    Published on:

  30. Canakinumab is a fully human anti-interleukin IL-1beta monoclonal antibody, being investigated for the treatment of rheumatoid arthritis (RA). This multicenter, phase II, randomized, double-blind, placebo-cont...

    Authors: Rieke Alten, Juan Gomez-Reino, Patrick Durez, Andre Beaulieu, Anthony Sebba, Gerhard Krammer, Ralph Preiss, Udayasankar Arulmani, Albert Widmer, Xavier Gitton and Herbert Kellner

    Citation: BMC Musculoskeletal Disorders 2011 12:153

    Content type: Research article

    Published on:

  31. There remains uncertainty regarding the appropriate therapeutic management of hip fracture patients. The primary aim of our study was to examine whether large loading doses in addition to daily vitamin D offer...

    Authors: Alexandra Papaioannou, Courtney C Kennedy, Lora Giangregorio, George Ioannidis, Janet Pritchard, David A Hanley, Leonardo Farrauto, Justin DeBeer and Jonathan D Adachi

    Citation: BMC Musculoskeletal Disorders 2011 12:135

    Content type: Research article

    Published on:

  32. Recent systematic reviews on psychological therapies of fibromyalgia syndrome (FMS) did not consider hypnosis/guided imagery (H/GI). Therefore we performed a systematic review with meta-analysis of the efficac...

    Authors: Kathrin Bernardy, Nicole Füber, Petra Klose and Winfried Häuser

    Citation: BMC Musculoskeletal Disorders 2011 12:133

    Content type: Research article

    Published on:

  33. Gout prevalence increased in recent years to become one of the most common causes of inflammatory arthritis in most industrialised countries. Comorbidities may affect the disease severity and treatment pattern...

    Authors: Paola Primatesta, Estel Plana and Dietrich Rothenbacher

    Citation: BMC Musculoskeletal Disorders 2011 12:103

    Content type: Research article

    Published on:

  34. Although trazodone is frequently used by fibromyalgia patients, its efficacy on this disease has not been adequately studied. If effective, pregabalin, whose beneficial effects on pain and sleep quality in fib...

    Authors: Elena P Calandre, Piedad Morillas-Arques, Rocío Molina-Barea, Carmen M Rodriguez-Lopez and Fernando Rico-Villademoros

    Citation: BMC Musculoskeletal Disorders 2011 12:95

    Content type: Research article

    Published on:

  35. Patients' values and preferences are fundamental tenets of evidence-based practice, yet current osteoporosis (OP) clinical guidelines pay little attention to these issues in therapeutic decision making. This m...

    Authors: Joanna EM Sale, Monique A Gignac, Gillian Hawker, Lucy Frankel, Dorcas Beaton, Earl Bogoch and Victoria Elliot-Gibson

    Citation: BMC Musculoskeletal Disorders 2011 12:92

    Content type: Research article

    Published on:

  36. To compare the prescription modalities of general practitioners (GPs) and rheumatologists (RHs) for symptomatic knee osteoarthritis (OA) and to determine correlates with prescription of low-dose NSAIDs.

    Authors: Pascal Richette, Pascal Hilliquin, Philippe Bertin, Paolo Carni, Véronique Berger and Marc Marty

    Citation: BMC Musculoskeletal Disorders 2011 12:72

    Content type: Research article

    Published on:

  37. Previous research has shown a loss of bone mineral density (BMD) during pregnancy. This loss has been correlated to the occurrence of back pain symptoms during pregnancy. The objective of this study was to eva...

    Authors: William WK To and Margaret WN Wong

    Citation: BMC Musculoskeletal Disorders 2011 12:55

    Content type: Research article

    Published on:

  38. This pretrial study aimed to develop and test the usability of a four-week Internet intervention delivered by a Web-enabled mobile phone to support self-management of chronic widespread pain.

    Authors: Ólöf Birna Kristjánsdóttir, Egil A Fors, Erlend Eide, Arnstein Finset, Sandra van Dulmen, Sigrid Hørven Wigers and Hilde Eide

    Citation: BMC Musculoskeletal Disorders 2011 12:51

    Content type: Research article

    Published on:

  39. As many patients with rheumatoid arthritis (RA) have increased fat mass (FM) and increased frequency of cardiovascular diseases we evaluated if total physical activity (MET-hours) had impact on body compositio...

    Authors: Ann-Charlotte Elkan, Niclas Håkansson, Johan Frostegård and Ingiäld Hafström

    Citation: BMC Musculoskeletal Disorders 2011 12:13

    Content type: Research article

    Published on:

  40. This study in patients with rheumatoid arthritis (RA) treated with infliximab describes prospectively the course of (anti)infliximab levels within an infusioncycle to assess at what moment patients develop low...

    Authors: Bart JF van den Bemt, Alfons A den Broeder, GJ Wolbink, Yechiel A Hekster, Piet LCM van Riel, Bart Benraad and Frank HJ van den Hoogen

    Citation: BMC Musculoskeletal Disorders 2011 12:12

    Content type: Research article

    Published on:

  41. Patterns of food intake and prevalent osteoarthritis of the hand, hip, and knee were studied using the twin design to limit the effect of confounding factors. Compounds found in associated food groups were fur...

    Authors: Frances MK Williams, Jane Skinner, Tim D Spector, Aedin Cassidy, Ian M Clark, Rose M Davidson and Alex J MacGregor

    Citation: BMC Musculoskeletal Disorders 2010 11:280

    Content type: Research article

    Published on:

  42. Osteoarthritis (OA) is a common degenerative joint disease causing pain, stiffness, reduced motion, swelling, crepitus, and disability. Dickkopf-1 (Dkk-1) is a critical mediator of osteoblastogenesis and regul...

    Authors: Sittisak Honsawek, Aree Tanavalee, Pongsak Yuktanandana, Srihatach Ngarmukos, Natthaphon Saetan and Saran Tantavisut

    Citation: BMC Musculoskeletal Disorders 2010 11:257

    Content type: Research article

    Published on:

2019 Journal Metrics