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Clinical rheumatology and osteoporosis

This section concerns all aspects of research into osteoporosis and rheumatic diseases, where the primary focus relates specifically to a component(s) of the musculoskeletal system

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  1. Content type: Study protocol

    Evidence on the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis is limited and conflicting. The primary objective of the Hip Injection Trial (HIT) is to compare pain intensity ...

    Authors: Zoe Paskins, Gemma Hughes, Helen Myers, Emily Hughes, Susie Hennings, Andrea Cherrington, Amy Evans, Melanie Holden, Kay Stevenson, Ajit Menon, Kieran Bromley, Philip Roberts, Alison Hall, George Peat, Clare Jinks, Raymond Oppong…

    Citation: BMC Musculoskeletal Disorders 2018 19:218

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  2. Content type: Research article

    Vitamin D (VD) insufficiency or deficiency is a frequent comorbidity in Chinese women with postmenopausal osteoporosis (PMO). The present study aimed to investigate 25-hydroxyvitamin D [25(OH) D] improvement a...

    Authors: Er-Yuan Liao, Zhen-Lin Zhang, Wei-Bo Xia, Hua Lin, Qun Cheng, Li Wang, Yong-Qiang Hao, De-Cai Chen, Hai Tang, Yong-De Peng, Li You, Liang He, Zhao-Heng Hu, Chun-Li Song, Fang Wei, Jue Wang…

    Citation: BMC Musculoskeletal Disorders 2018 19:210

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  3. Content type: Research article

    Osteoarthritis (OA) is the most common joint disorder worldwide and one of the leading causes of disability in the elderly. We have investigated the novel sodium hyaluronate derivative chemically linked with d...

    Authors: Keiji Yoshioka, Tomochika Kisukeda, Ryoji Zuinen, Yosuke Yasuda and Kenji Miyamoto

    Citation: BMC Musculoskeletal Disorders 2018 19:157

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  4. Content type: Research article

    Dutasteride is a potent inhibitor of 5-alpha reductase enzymes that reduces concentrations of dihydrotestosterone to a greater extent than finasteride. Whether this has adverse implications for bone health is ...

    Authors: Tony Antoniou, Erin M. Macdonald, Zhan Yao, Tara Gomes, Mina Tadrous, Joanne M.-W. Ho, Muhammad M. Mamdani and David N. Juurlink

    Citation: BMC Musculoskeletal Disorders 2018 19:160

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  5. Content type: Research article

    Knowledge on prevalence of osteoporosis stratifying for socioeconomic background is insufficient in Germany. Little is known in Europe about other diseases that go along with it although these aspects are impo...

    Authors: Marie-Therese Puth, Manuela Klaschik, Matthias Schmid, Klaus Weckbecker and Eva Münster

    Citation: BMC Musculoskeletal Disorders 2018 19:144

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  6. Content type: Research article

    Several studies looking into the association between insulin-like growth factor-1 (IGF-1) gene polymorphisms and osteoporosis predisposition have been conducted among Chinese population with conflicting outcom...

    Authors: Shu-tao Gao, Zheng-tao Lv, Chuan-kun Zhou, Chao Mao and Wei-bin Sheng

    Citation: BMC Musculoskeletal Disorders 2018 19:141

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  7. Content type: Study protocol

    To increase the uptake of key clinical recommendations for non-surgical management of knee osteoarthritis (OA) and improve patient outcomes, we developed a new model of service delivery (PARTNER model) and an ...

    Authors: David J. Hunter, Rana S. Hinman, Jocelyn L. Bowden, Thorlene Egerton, Andrew M. Briggs, Stephen J. Bunker, Jessica Kasza, Andrew B. Forbes, Simon D. French, Marie Pirotta, Deborah J. Schofield, Nicholas A. Zwar and Kim L. Bennell

    Citation: BMC Musculoskeletal Disorders 2018 19:132

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  8. Content type: Case report

    Inflammatory back pain is a condition characterized by inflammation of the sacroiliac joints and lower spine. It is frequently seen in patients with spondyloarthropathies like ankylosing spondylitis, psoriatic...

    Authors: Safi Alqatari, Roberta Visevic, Nina Marshall, John Ryan and Grainne Murphy

    Citation: BMC Musculoskeletal Disorders 2018 19:126

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  9. Content type: Study protocol

    Osteoporotic vertebral fractures are common, and are associated with reduced functioning and health related quality of life. The primary aims of this randomized controlled trial are to examine the immediate an...

    Authors: Brita Stanghelle, Hege Bentzen, Lora Giangregorio, Are Hugo Pripp and Astrid Bergland

    Citation: BMC Musculoskeletal Disorders 2018 19:100

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  10. Content type: Study protocol

    The prevalence of hand osteoarthritis (HOA) has been reported to be higher amongst women over 50 years old (66%) compared to men of the same age (34%). Although exercise therapy has been shown effective in red...

    Authors: Paulette Guitard, Lucie Brosseau, George A. Wells, Nicole Paquet, Gail Paterson, Karine Toupin-April, Sabrina Cavallo, Sibel Z. Aydin, Guillaume Léonard and Gino De Angelis

    Citation: BMC Musculoskeletal Disorders 2018 19:56

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  11. Content type: Research article

    Impaired bone quality is associated with poor outcome of spinal surgery. The aim of the study was to assess the bone mineral status of patients scheduled to undergo spinal surgery and to report frequencies of ...

    Authors: Tobias Schmidt, Katharina Ebert, Tim Rolvien, Nicola Oehler, Jens Lohmann, Luca Papavero, Ralph Kothe, Michael Amling, Florian Barvencik and Haider Mussawy

    Citation: BMC Musculoskeletal Disorders 2018 19:53

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  12. Content type: Research article

    Dupuytren’s disease (DD) is a common and progressive, fibroproliferative disorder of the palmar and digital fascia of the hand. Various treatments have been recommended for advanced disease or to retard progre...

    Authors: Melina Dritsaki, Oliver Rivero-Arias, Alastair Gray, Catherine Ball and Jagdeep Nanchahal

    Citation: BMC Musculoskeletal Disorders 2018 19:34

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  13. Content type: Research article

    The roles of C-reactive protein (CRP) and cartilage oligomeric matrix protein (COMP) in knee osteoarthritis (KOA) remain controversial, thus the present study is aimed to explore the relationships between CRP,...

    Authors: Junfeng Zhang

    Citation: BMC Musculoskeletal Disorders 2018 19:22

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  14. Content type: Research article

    Pain is the principal clinical symptom of osteoarthritis (OA), and development of safe and effective analgesics for OA pain is needed. Drug development of new analgesics for OA pain is impaired by substantial ...

    Authors: Asger Reinstrup Bihlet, Inger Byrjalsen, Anne-Christine Bay-Jensen, Jeppe Ragnar Andersen, Claus Christiansen, Bente Juel Riis, Ivo Valter, Morten A. Karsdal and Marc C. Hochberg

    Citation: BMC Musculoskeletal Disorders 2018 19:17

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  15. Content type: Research article

    Associations between adipokines and bone mineral density (BMD) in knee osteoarthritis (OA) remain indistinct. The aim of this study was to investigate the cross-sectional associations between serum levels of a...

    Authors: Juan Wu, Jianhua Xu, Kang Wang, Qicui Zhu, Jingyu Cai, Jiale Ren, Shuang Zheng and Changhai Ding

    Citation: BMC Musculoskeletal Disorders 2018 19:16

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  16. Content type: Research article

    Intra-articular hyaluronic acid (IA-HA) is a common therapy used to treat knee pain and suppress knee inflammation in knee osteoarthritis (OA), typically prescribed in regimens ranging from a single injection ...

    Authors: Andrew Concoff, Parag Sancheti, Faizan Niazi, Peter Shaw and Jeffrey Rosen

    Citation: BMC Musculoskeletal Disorders 2017 18:542

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  17. Content type: Research article

    Despite the widely known benefits of exercise and physical activity, adherence rates to these activities are poor. Understanding exercise facilitators, barriers, and preferences may provide an opportunity to p...

    Authors: Isabel B. Rodrigues, Jonathan D. Adachi, Karen A. Beattie and Joy C. MacDermid

    Citation: BMC Musculoskeletal Disorders 2017 18:540

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  18. Content type: Research article

    We used High Resolution – peripheral Quantitative CT (HR-pQCT) imaging to examine peri-articular bone quality in early rheumatoid arthritis (RA) and explore whether bone quality improved over 12-months in indi...

    Authors: Lynne M. Feehan, Linda L. Li and Heather A. McKay

    Citation: BMC Musculoskeletal Disorders 2017 18:521

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  19. Content type: Research article

    The Lower Limb Assessment Score (LLAS) has only been validated in a paediatric population. The aim of this study was to validate the use of the LLAS in an adult population by: i) evaluating its ability to disc...

    Authors: Kaitlin J. Meyer, Cliffton Chan, Luke Hopper and Leslie L. Nicholson

    Citation: BMC Musculoskeletal Disorders 2017 18:514

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  20. Content type: Research article

    Oscarvit (OSC) is an in-house preparation consisting of calcium, magnesium, phosphorus, strontium, Vitamin D, and eggshell membrane hydrolysate containing naturally occurring glycosaminoglycans and sulfated gl...

    Authors: Tibor Görögh, Elgar S. Quabius, Alexander Georgitsis, Markus Hoffmann and Sebastian Lippross

    Citation: BMC Musculoskeletal Disorders 2017 18:500

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