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Clinical diagnostics and imaging

Section edited by Daichi Hayashi

This section concerns clinical and research studies of the clinical diagnosis of musculoskeletal disorders focusing on musculoskeletal radiology and diagnostic imaging of musculoskeletal disorders.  

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  1. Content type: Research article

    MRI analysis of subtalar ligaments in the tarsal sinus has not been well performed. We retrospectively investigated the appearance of subtalar ligaments using 3D isotropic MRI and compared imaging findings of ...

    Authors: Tae Hyung Kim, Sung Gyu Moon, Hong-Geun Jung and Na Ra Kim

    Citation: BMC Musculoskeletal Disorders 2017 18:475

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  2. Content type: Research article

    Previous studies on shoulder patients have suggested that the prevalence of rotator cuff or bursa abnormalities are weakly related to symptoms and that similar findings are often found in asymptomatic persons....

    Authors: Elisabeth Kvalvaag, Masoud Anvar, Anna Cecilia Karlberg, Jens Ivar Brox, Kaia Beck Engebretsen, Helene Lundgaard Soberg, Niels Gunnar Juel, Erik Bautz-Holter, Leiv Sandvik and Cecilie Roe

    Citation: BMC Musculoskeletal Disorders 2017 18:469

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  3. Content type: Research article

    Recent morphological analyses of vertebrae in patients with scoliosis have revealed three-dimensional (3D) deformities in the vertebral bodies. However, it remains controversial whether these deformities are s...

    Authors: Takahiro Makino, Yusuke Sakai, Masafumi Kashii, Shota Takenaka, Kazuomi Sugamoto, Hideki Yoshikawa and Takashi Kaito

    Citation: BMC Musculoskeletal Disorders 2017 18:459

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  4. Content type: Research article

    To determine effects of allogeneic human chondrocytes expressing TGF-β1 (TG-C) on structural progression of MRI features of knee osteoarthritis over a 1 year period.

    Authors: A. Guermazi, G. Kalsi, J. Niu, M. D. Crema, R. O. Copeland, A. Orlando, M. J. Noh and F. W. Roemer

    Citation: BMC Musculoskeletal Disorders 2017 18:461

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  5. Content type: Research article

    This study aims to investigate the technical feasibility of semi-quantitative and quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in the assessment of longitudinal changes of marrow...

    Authors: Jingqi Zhu, Zuogang Xiong, Jiulong Zhang, Yuyou Qiu, Ting Hua and Guangyu Tang

    Citation: BMC Musculoskeletal Disorders 2017 18:446

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  6. Content type: Research article

    Systemic sclerosis can affect peripheral nerves, but the extent and the nature of this involvement are not well defined. The aim of this study is to compare the sonoelastrographic measurements of median nerves...

    Authors: Ilker Yagci, Ozge Kenis-Coskun, Tugba Ozsoy, Gulsen Ozen and Haner Direskeneli

    Citation: BMC Musculoskeletal Disorders 2017 18:434

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  7. Content type: Research article

    Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterized by severe hypophosphatemia and osteomalacia. Nonspecific symptoms make the diagnosis elusive. In addition, locating the responsi...

    Authors: Qing-yao Zuo, Hong Wang, Wei Li, Xiao-hui Niu, Yan-hong Huang, Jia Chen, Yu-hua You, Bao-yue Liu, Ai-min Cui and Wei Deng

    Citation: BMC Musculoskeletal Disorders 2017 18:403

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  8. Content type: Research article

    The aim of this study was to quantitatively evaluate and characterize the dimension and signal intensity of anterior talofibular ligament (ATFL) using 3.0 T MRI in the mechanical ankle instability group pre- a...

    Authors: Wei Liu, Hong Li and Yinghui Hua

    Citation: BMC Musculoskeletal Disorders 2017 18:397

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  9. Content type: Research article

    Musculoskeletal ultrasound improves the accuracy of detecting the level of disease activity (DA) in RA patients, although its impact on the final treatment decision in a real clinical setting is uncertain. The...

    Authors: C. Sifuentes-Cantú, I. Contreras-Yáñez, L. Saldarriaga, A.C. Lozada, M. Gutiérrez and V. Pascual-Ramos

    Citation: BMC Musculoskeletal Disorders 2017 18:390

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  10. Content type: Research article

    Inclination and anteversion were the main factors that determined the reliability of the acetabulum. Inclination and anteversion measurements included anatomical, operational and radiographic methods. The aim ...

    Authors: R. Y. Wang, W. H. Xu, X. C. Kong, L. Yang and S. H. Yang

    Citation: BMC Musculoskeletal Disorders 2017 18:373

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  11. Content type: Research article

    This study uses virtual touch imaging quantification (VTIQ) technology for the first time to conduct measurements of the trapezius and erector spinae muscles in a large study population. The significance of va...

    Authors: Anne Heizelmann, Sümeyra Tasdemir, Julian Schmidberger, Tilmann Gräter, Wolfgang Kratzer and Beate Grüner

    Citation: BMC Musculoskeletal Disorders 2017 18:370

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  12. Content type: Research article

    The purpose of our study was to assess the clinical and imaging outcome of autologous matrix-induced chondrogenesis (AMIC) technique consisting of microfractures followed by the filling of osteochondral lesion...

    Authors: Domenico Albano, Nicolò Martinelli, Alberto Bianchi, Carmelo Messina, Francesco Malerba and Luca Maria Sconfienza

    Citation: BMC Musculoskeletal Disorders 2017 18:306

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  13. Content type: Research article

    Modic changes (MC) are associated with low back pain (LBP). In this study, we compared changes in size and type of MC, after a single intravenous infusion of 5 mg zoledronic acid (ZA) or placebo, among chronic...

    Authors: Katri Koivisto, Jyri Järvinen, Jaro Karppinen, Marianne Haapea, Markus Paananen, Eero Kyllönen, Osmo Tervonen and Jaakko Niinimäki

    Citation: BMC Musculoskeletal Disorders 2017 18:274

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  14. Content type: Research article

    Acromial morphology has previously been defined as a risk factor for some shoulder pathologies. Yet, study results are inconclusive and not all major shoulder diseases have been sufficiently investigated. Thus...

    Authors: Philipp R. Heuberer, Fabian Plachel, Lukas Willinger, Philipp Moroder, Brenda Laky, Leo Pauzenberger, Fritz Lomoschitz and Werner Anderl

    Citation: BMC Musculoskeletal Disorders 2017 18:259

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  15. Content type: Review

    Magnetic resonance (MR) imaging plays an important role in the evaluation of bacterial and tuberculous spondylodiscitis and associated complications. Owing to its high sensitivity and specificity, it is a powe...

    Authors: Yogesh Kumar, Nishant Gupta, Avneesh Chhabra, Takeshi Fukuda, Neetu Soni and Daichi Hayashi

    Citation: BMC Musculoskeletal Disorders 2017 18:244

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  16. Content type: Research article

    Several studies have explored cervical kyphosis (CK) in adolescent idiopathic scoliosis (AIS) patients. However, few studies have evaluated the cervical alignment in these patients according to their coronal c...

    Authors: Ce Zhu, Xi Yang, Bangjian Zhou, Lei Wang, Chunguang Zhou, Tingxian Ling, Limin Liu and Yueming Song

    Citation: BMC Musculoskeletal Disorders 2017 18:220

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  17. Content type: Research article

    Prior studies describe histological and immunohistochemical differences in collagen and proteoglycan content in different meniscal zones. The aim of this study is to evaluate horizontal and vertical zonal diff...

    Authors: Shoichiro Takao, Tan B. Nguyen, Hon J. Yu, Shigeo Hagiwara, Yasuhito Kaneko, Taiki Nozaki, Seiji Iwamoto, Maki Otomo, Ran Schwarzkopf and Hiroshi Yoshioka

    Citation: BMC Musculoskeletal Disorders 2017 18:202

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  18. Content type: Research article

    Radiographic features of lumbar disc degeneration (LDD) are common findings in patients with chronic mechanical low back pain; however, its role in disability and intensity of pain is debatable. This study aim...

    Authors: Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake and Vajira Harshadeva Weerabaddana Dissanayake

    Citation: BMC Musculoskeletal Disorders 2017 18:193

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  19. Content type: Case report

    Radiographic sacroiliitis is the hallmark of ankylosing spondylitis (AS), and detection of acute sacroiliitis is pivotal for early diagnosis of AS. Although radiographic sacroiliitis is a distinguishing featur...

    Authors: Maria J. Antonelli and Marina Magrey

    Citation: BMC Musculoskeletal Disorders 2017 18:170

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  20. Content type: Case report

    Enchondroma, a subtype of chondroma, originates from the medullary cavity of the bone and produces an expansile growth pattern. Enchondroma located in the spine is rare and a few cases of large thoracic enchon...

    Authors: Jing Guo, Ju-zhou Gao, Lian-jin Guo, Zhi-xun Yin and Er-xing He

    Citation: BMC Musculoskeletal Disorders 2017 18:155

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  21. Content type: Case report

    Posterior epidural migration of lumbar disc fragments (PEMLDF) is extremely rare. It is often confused with other posterior lesions and is usually diagnosed intraoperatively. We here describe the use of preope...

    Authors: Morito Takano, Tomohiro Hikata, Soraya Nishimura and Michihiro Kamata

    Citation: BMC Musculoskeletal Disorders 2017 18:151

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  22. Content type: Research article

    Rheumatoid Arthritis (RA) is associated with an increased risk of cardiovascular disease (CVD). The physical dysfunction symptomatic of RA means people living with this disease spend large periods of the day s...

    Authors: Sally A. M. Fenton, Jet J. C. S. Veldhuijzen van Zanten, George D. Kitas, Joan L. Duda, Peter C. Rouse, Chen-an Yu and George S. Metsios

    Citation: BMC Musculoskeletal Disorders 2017 18:131

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  23. Content type: Research article

    Treatment of clavicular non- and malunion is still challenging. Current surgical procedures often result in frustrating functional outcome along with high-grade subjective impairment and increased rates of rev...

    Authors: Marc Beirer, Ingo J. Banke, Norbert Harrasser, Moritz Crönlein, Dominik Pförringer, Stefan Huber-Wagner, Peter Biberthaler and Chlodwig Kirchhoff

    Citation: BMC Musculoskeletal Disorders 2017 18:129

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  24. Content type: Research article

    A previous study reported a high prevalence of spinal epidural lipomatosis (SEL) in patients with Scheuermann kyphosis (SK) and suggested that it may play a role in the pathogenesis of this disease. According ...

    Authors: Zhen Zhang, Zhen Liu, Zezhang Zhu and Yong Qiu

    Citation: BMC Musculoskeletal Disorders 2017 18:112

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  25. Content type: Research article

    Clinical swollen joint examination of the obese rheumatoid arthritis (RA) patient can be difficult. Musculoskeletal Ultrasound (MSUS) has higher sensitivity than physical examination for swollen joints (SJ). T...

    Authors: Erin M. Bauer, Ami Ben-Artzi, Erin L. Duffy, David A. Elashoff, Sitaram S. Vangala, John Fitzgerald and Veena K. Ranganath

    Citation: BMC Musculoskeletal Disorders 2017 18:99

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  26. Content type: Research article

    Lumbar radiculopathy remains a clinical challenge among primary care clinicians in both assessment and diagnosis. This often leads to misdiagnosis and inappropriate treatment of patients resulting in poor heal...

    Authors: Nassib Tawa, Anthea Rhoda and Ina Diener

    Citation: BMC Musculoskeletal Disorders 2017 18:93

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  27. Content type: Research article

    The primary objective of this study was to assess the interobserver and intraobserver agreement on ligamentous injuries on conventional magnetic resonance imaging (MRI) in acute simple elbow dislocation. The s...

    Authors: Marc Schnetzke, Svenja Schüler, Johannes Hoffend, Rainer Simon, Holger Keil, Felix Porschke, Stefan Studier-Fischer, Paul-Alfred Grützner and Thorsten Guehring

    Citation: BMC Musculoskeletal Disorders 2017 18:85

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  28. Content type: Research article

    Several types of Magnetic resonance imaging (MRI) are commonly used in imaging of femoroacetabular impingement (FAI), however till now there are no clear protocols and recommendations for each type. The aim of...

    Authors: A. M. Saied, C. Redant, M. El-Batouty, M. R. El-Lakkany, W. A. El-Adl, J. Anthonissen, R. Verdonk and E. A. Audenaert

    Citation: BMC Musculoskeletal Disorders 2017 18:83

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  29. Content type: Research article

    Acetabular dysplasia (AD) is a well-known cause of osteoarthritis (OA) of the hip, with its prevalence previously determined on plain radiography. The prevalence of preexisting AD was reported as 7.3% in a pat...

    Authors: Tomohiro Mimura, Kanji Mori, Masahiro Kitagawa, Mariko Ueki, Yuki Furuya, Taku Kawasaki and Shinji Imai

    Citation: BMC Musculoskeletal Disorders 2017 18:50

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  30. Content type: Research article

    Spinal deformities affect the overall alignment of the spine and thus the vectors of loading on the lumbar region and intervertebral discs. Due to wedging of the disc or vertebrae of unbalanced spinal segments...

    Authors: Kamil Eyvazov, Dino Samartzis and Jason Pui Yin Cheung

    Citation: BMC Musculoskeletal Disorders 2017 18:51

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  31. Content type: Research article

    Due to the risk associated with exposure to ionizing radiation, there is an urgent need to identify areas of CT scanning overutilization. While increased use of diagnostic spinal imaging has been documented, n...

    Authors: Vikas V. Patel, Gunnar B. J. Andersson, Steven R. Garfin, Donald L. Resnick and Jon E. Block

    Citation: BMC Musculoskeletal Disorders 2017 18:52

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  32. Content type: Research article

    Research has suggested that patient expectations are associated with treatment outcome and evolve along with patient communication within the musculoskeletal field. However, few studies have investigated if or...

    Authors: Sigrid Skatteboe, Cecilie Røe, Morten Wang Fagerland and Lars-Petter Granan

    Citation: BMC Musculoskeletal Disorders 2017 18:48

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  33. Content type: Research article

    Some cadaveric studies have reported the role of the distal oblique bundle (DOB) in the distal radioulnar joint stability. We aimed to determine whether the presence of the DOB can be identified and its thickn...

    Authors: Yeon Ho Kim, Hyun Sik Gong, Jin Woo Park, Hyun Kyung Yang, Kahyun Kim and Goo Hyun Baek

    Citation: BMC Musculoskeletal Disorders 2017 18:47

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  34. Content type: Research article

    Physical examination tests of the shoulder (PETS) are clinical examination maneuvers designed to aid the assessment of shoulder complaints. Despite more than 180 PETS described in the literature, evidence of t...

    Authors: Sigmund Ø. Gismervik, Jon O. Drogset, Fredrik Granviken, Magne Rø and Gunnar Leivseth

    Citation: BMC Musculoskeletal Disorders 2017 18:41

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  35. Content type: Research article

    Modic 1 changes are usually associated with degenerative disc disease (DDD). We aimed to compare Modic 1 changes with advanced degenerative disc disease (>50%-intervertebral space narrowing [IVSN]) to Modic 1 ...

    Authors: Christelle Nguyen, Marylène Jousse, Serge Poiraudeau, Antoine Feydy and François Rannou

    Citation: BMC Musculoskeletal Disorders 2017 18:34

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  36. Content type: Case report

    Osteoid osteoma (OO) is a common benign bone tumour that is rarely found in the talus. Its nidus is difficult to detect on early imaging. The atypical symptoms of OO and the presence of concurrent trauma or sp...

    Authors: Huan He, Hailin Xu, Hao Lu, Yu Dang, Wei Huang and Qing Zhang

    Citation: BMC Musculoskeletal Disorders 2017 18:35

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  37. Content type: Technical advance

    There is increasing interest in paravertebral muscle composition as a potential prognostic and diagnostic element in lumbar spine health. As a consequence, it is becoming popular to use magnetic resonance imag...

    Authors: Rebecca J. Crawford, Jon Cornwall, Rebecca Abbott and James M. Elliott

    Citation: BMC Musculoskeletal Disorders 2017 18:25

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  38. Content type: Research article

    Our study aimed to investigate whether geometrical features (size, shape, or alignment parameters) of the femoral condyle affect the morphology of the trochlear groove.

    Authors: Zhe Du, Shichang Chen, Mengning Yan, Bing Yue, Yiming Zeng and You Wang

    Citation: BMC Musculoskeletal Disorders 2017 18:4

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  39. Content type: Research article

    The Digital X-ray Radiogrammetry (DXR) method measures the cortical bone thickness in the shafts of the metacarpals and has demonstrated its relevance in the assessment of hand bone loss caused by rheumatoid a...

    Authors: Alexander Pfeil, Hans Henrik Thodberg, Diane M. Renz, Lisa Reinhardt, Peter Oelzner, Gunter Wolf and Joachim Böttcher

    Citation: BMC Musculoskeletal Disorders 2017 18:6

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  40. Content type: Research article

    Supra/interspinous ligaments connect adjacent spinous processes and act as a stabilizer of the spine. As with other spinal ligaments, it can become ossified. However, few report have discussed ossification sup...

    Authors: Kanji Mori, Toshitaka Yoshii, Takashi Hirai, Akio Iwanami, Kazuhiro Takeuchi, Tsuyoshi Yamada, Shoji Seki, Takashi Tsuji, Kanehiro Fujiyoshi, Mitsuru Furukawa, Soraya Nishimura, Kanichiro Wada, Masao Koda, Takeo Furuya, Yukihiro Matsuyama, Tomohiko Hasegawa…

    Citation: BMC Musculoskeletal Disorders 2016 17:492

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  41. Content type: Research article

    Osteoporosis, osteoporosis-related fractures, and diabetes are considerable health burdens in Japan. Diabetes in patients with osteoporosis has been reported to be associated with increased fracture risk. This...

    Authors: Masayo Sato, Wenyu Ye, Tomoko Sugihara and Yoshitaka Isaka

    Citation: BMC Musculoskeletal Disorders 2016 17:489

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  42. Content type: Research article

    Fluid in the subcutaneous fat is a common finding anterior to the knee on MRI. This may be caused by chronic low-grade shearing injuries in patients who are overweight. The purpose of this study was to determi...

    Authors: Trevor Gaunt, Frank Carey, John Cahir and Andoni Toms

    Citation: BMC Musculoskeletal Disorders 2016 17:487

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    The Erratum to this article has been published in BMC Musculoskeletal Disorders 2017 18:1

  43. Content type: Case report

    The overlap syndrome of primary biliary cholangitis (formerly called primary biliary cirrhosis) and primary sclerosing cholangitis is an extremely rare condition that has never been described in association wi...

    Authors: Teresa Del Ross, Amelia Ruffatti, Annarosa Floreani, Ariela Hoxha and Leonardo Punzi

    Citation: BMC Musculoskeletal Disorders 2016 17:485

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  44. Content type: Research article

    Bone marrow lesions (BMLs) in knee osteoarthritis (OA) can be assessed using fluid sensitive and contrast enhanced sequences. The association between BMLs and symptoms has been investigated in several studies ...

    Authors: Flemming K. Nielsen, Niels Egund, Anette Jørgensen, David A. Peters and Anne Grethe Jurik

    Citation: BMC Musculoskeletal Disorders 2016 17:479

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  45. Content type: Research article

    To describe the scoring methodology and MRI assessments used to evaluate the cross-sectional features observed in cases and controls, to define change over time for different MRI features, and to report the ex...

    Authors: Frank W. Roemer, Ali Guermazi, Jamie E. Collins, Elena Losina, Michael C. Nevitt, John A. Lynch, Jeffrey N. Katz, C. Kent Kwoh, Virginia B. Kraus and David J. Hunter

    Citation: BMC Musculoskeletal Disorders 2016 17:466

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  46. Content type: Research article

    Pseudotumors associated with metal-on-metal hips can be symptomatic or asymptomatic. The purpose of this study was to identify the characteristics of pseudotumors associated with pain.

    Authors: Masahiro Hasegawa, Yohei Naito, Toshio Yamaguchi, Shinichi Miyazaki, Hiroki Wakabayashi and Akihiro Sudo

    Citation: BMC Musculoskeletal Disorders 2016 17:456

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  47. Content type: Research article

    The aim of this retrospective study was to investigate the frequency of intra-articular osteoid osteoma (iaOO) in a large study cohort and to demonstrate its clinical relevance as an important differential dia...

    Authors: Tim Rolvien, Jozef Zustin, Haider Mussawy, Tobias Schmidt, Pia Pogoda and Peter Ueblacker

    Citation: BMC Musculoskeletal Disorders 2016 17:455

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  48. Content type: Case report

    Kirner’s deformity is a rare bony deformity that is characterized by radial and volar curvature of the distal phalanx of the fifth finger. Affected patients usually present after the age of 5 years, with girls...

    Authors: Melkamu Adeb, Daichi Hayashi and Yogesh Kumar

    Citation: BMC Musculoskeletal Disorders 2016 17:440

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  49. Content type: Research article

    Degenerative disc disease of the lumbar spine is common, with severe disease increasing the risk for chronic low back pain. This cross-sectional study examined whether disc degeneration is representative of a ...

    Authors: Andrew J. Teichtahl, Donna M. Urquhart, Yuanyuan Wang, Anita E. Wluka, Richard O’Sullivan, Graeme Jones and Flavia M. Cicuttini

    Citation: BMC Musculoskeletal Disorders 2016 17:439

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