Clinical diagnostics and imaging

Letter to the Editor: Non-selective bilateral internal iliac artery embolization is a safe and effective way in hemorrhage control for hemodynamically unstable pelvic fractures

A recently published article by Lai et al. in BMC Musculoskeletal Disorders trying to show that patients with pelvic fractures undergoing non-selective internal iliac artery embolization may lead to a higher r...

Authors: Hui Li and Ping Hu

Severe erosive lesion of the glenoid in gouty shoulder arthritis: a case report and review of the literature

Gout is a metabolic disease characterized by recurrent episodes of acute arthritis. Gout has been reported in many locations but is rarely localized in the shoulder joint. We describe a rare case of gouty arth...

Authors: Huricha Bao, Yansong Qi, Baogang Wei, Bingxian Ma, Yongxiang Wang and Yongsheng Xu

Frailty as a risk factor for postoperative complications in adult patients with degenerative scoliosis administered posterior single approach, long-segment corrective surgery: a retrospective cohort study

With the population aging worldwide, adult degenerative scoliosis (ADS) is receiving increased attention. Frailty, instead of chronological age, is used for assessing the patient’s overall physical condition. ...

Authors: Bin Li, Xianglong Meng, Xinuo Zhang and Yong Hai

The trochanteric double contour is a valuable landmark for assessing femoral offset underestimation on standard radiographs: a retrospective study

Inaccurate projection on standard pelvic radiographs leads to the underestimation of femoral offset—a critical determinant of postoperative hip function—during total hip arthroplasty (THA) templating. We noted...

Authors: Stefan Blümel, Vincent A. Stadelmann, Marco Brioschi, Alexander Küffer, Michael Leunig and Hannes A. Rüdiger

The evaluation of degeneration of posterior cruciate ligament using CT Hounsfield unit in knee osteoarthritis

Posterior cruciate ligament (PCL) degeneration is often seen in knee osteoarthritis (OA); however, there is no established method for its evaluation. The purpose of this study is to investigate whether the Hou...

Authors: Yoshikazu Sumida, Tomoyuki Nakasa, Masakazu Ishikawa, Atsuo Nakamae and Nobuo Adachi

Heterotopic ossification in the post cruciate ligament of the knee: a case report and literature review

Heterotopic ossification (HO) is noted most frequently in periarticular muscles and has not yet been reported in the cruciate ligaments of the knee. We present a rare case of symptomatic ossification of the po...

Authors: Cun Li, Zonggui Huang, K. C. Anil, Chendeng Lao, Qianghua Wu and Hongmian Jiang

Extending the straight leg raise test for improved clinical evaluation of sciatica: reliability of hip internal rotation or ankle dorsiflexion

The straight leg raise (SLR) is the most commonly applied physical tests on patients with sciatica, but the sensitivity and specificity ratings for disc hernia and neural compression leave areas for improvemen...

Authors: Janne Pesonen, Michael Shacklock, Pekka Rantanen, Jussi Mäki, Lauri Karttunen, Markku Kankaanpää, Olavi Airaksinen and Marinko Rade

An acquired plica-induced notch in the medial femoral condyle in a patient with medial patellar plica syndrome: a case report

An inflamed and thickened medial patellar plica (MPP) caused by repeated mechanical irritation from trauma or overuse leads to impingement between the anterior medial femoral condyle and the medial articular f...

Authors: Sung-Jae Kim, Yong Gon Koh and Yong Sang Kim

Early surgery with antibiotic medication was effective and efficient in treating pyogenic spondylodiscitis

Pyogenic spondylodiscitis (PSD) is challenging to the orthopedist with regards to diagnosis and treatment. The present study was designed to assess and suggest the most indicative diagnostic method and evaluat...

Authors: Wei Guo, Min Wang, Guangfu Chen, Kuan-Hung Chen, Yong Wan, Bailing Chen, Xuenong Zou and Xinsheng Peng

Isolated thoracic intramedullary Erdheim-Chester disease presenting with paraplegia: a case report and literature review

Erdheim-Chester disease (ECD) is a rare, idiopathic, systemic non-Langerhans cell histiocytosis involving long bone and visceral organs. Central nervous system (CNS) involvement is uncommon and most cases deve...

Authors: Ikchan Jeon and Joon Hyuk Choi

Longitudinal study of MRI and functional outcome measures in facioscapulohumeral muscular dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is a patchy and slowly progressive disease of skeletal muscle. For MRI to be a useful biomarker in an FSHD clinical trial, it should reliably detect changes over r...

Authors: Leo H. Wang, Dennis W. W. Shaw, Anna Faino, Christopher B. Budech, Leann M. Lewis, Jeffrey Statland, Katy Eichinger, Stephen J. Tapscott, Rabi N. Tawil and Seth D. Friedman

Invited reply to the letter to the editor by McNally et al., 2021

Authors: Christian Morgenstern, Nora Renz, Sabrina Cabric, Elena Maiolo, Carsten Perka and Andrej Trampuz

The importance of appropriate diagnostics in prosthetic joint infection: letter to the editor of BMC musculoskeletal disorders

Assessment of a new diagnostic test must be performed against an acceptable and validated standard to allow comparison with other studies. We are concerned that the adoption of lower diagnostic criteria in thi...

Authors: Martin McNally, Marjan Wouthuyzen-Bakker, Ricardo Sousa, Bridget Atkins and Alex Soriano

Exercise-induced muscle damage: multi-parametric MRI quantitative assessment

To explore the value of magnetic resonance quantitative analysis using diffusion tensor imaging, T2 mapping, and intravoxel incoherent motion in the evaluation of eccentric exercise-induced muscle damage and t...

Authors: Xiaohong Lyu, Yue Gao, Qiang Liu, Heng Zhao, Huadong Zhou and Shinong Pan

Diagnosis and surgical treatment of primary isolated aggressive lumbar myeloid sarcoma: a rare case report and review of the literatures

Myeloid sarcoma is a rare, extramedullary, solid tumor derived from immature myeloid cell precursors. It is most frequently accompanied by acute myelogenous leukemia, though infrequently found in non-acute mye...

Authors: Cheng-Rui Bai, Xiang Li, Jing-Shi Wang, Jin-Jun Li, Ning Liu, Qi Fei, Dong Li and Yong Yang

Microbial yield from infectious tissues pretreated by various methods: an invitro study

This study aimed to evaluate the effects of different pretreatment methods on the microbial yield from infectious tissues.

Authors: Yuanqing Cai, Xinyu Fang, Lvheng Zhang, Xurong Yang, Lixiong Nie, Zida Huang, Wenbo Li, Chaofan Zhang, Bin Yang, Zhenpeng Guan and Wenming Zhang

Image classification of osteoporotic vertebral fracture with endplate-disc complex Injury

The purpose of this study was to use MRI and CT to observe osteoporosis vertebral fracture (OVF) combined with endplate-disc complex (EDC) injury and to classify the degree of EDC injury according to the chang...

Authors: Shuai Zhang, Song Wang, Qing Wang, Jin Yang and Shuang Xu

Dedifferentiated chondrsarcoma: a clinicopathologic analysis of 25 cases

To investigate the clinical, imaging and pathological features of dedifferentiated chondrosarcoma for better diagnosis.

Authors: Lei Cao, Yuan Wu, Shu-Man Han, Tao Sun, Bao-Hai Yu, Feng Gao, Wen-Juan Wu and Bu-Lang Gao

Diagnostic criteria for musculoskeletal disorders for use in occupational healthcare or research: a scoping review of consensus- and synthesised-based case definitions

The aim of this study was to identify case definitions of diagnostic criteria for specific musculoskeletal disorders (MSDs) for use in occupational healthcare, surveillance or research.

Authors: Henk F. van der Molen, Steven Visser, Jose Hernán Alfonso, Stefania Curti, Stefano Mattioli, David Rempel, Yves Roquelaure, P. Paul F. M. Kuijer and Sietske J. Tamminga

Minimally displaced unilateral facet fracture of cervical spine can lead to spinal cord injury: a report of two cases

According to most of the commonly used classification systems for subaxial spine injuries, unilateral and minimally displaced facet fractures without any sign of a spinal cord injury would be directed to non-o...

Authors: Satoshi Maki, Mitsuhiro Kitamura, Takeo Furuya, Takuya Miyamoto, Sho Okimatsu, Yasuhiro Shiga, Kazuhide Inage, Sumihisa Orita, Yawara Eguchi and Seiji Ohtori

Characteristics of relief and residual low back pain after discectomy in patients with lumbar disc herniation: analysis using a detailed visual analog scale

Several authors have reported favorable results in low back pain (LBP) for patients with lumbar disc herniation (LDH) treated with discectomy. However, detailed changes over time in the characteristics and loc...

Authors: Hiroshi Takahashi, Yasuchika Aoki, Masahiro Inoue, Junya Saito, Arata Nakajima, Masato Sonobe, Yorikazu Akatsu, Keita Koyama, Yasuhiro Shiga, Kazuhide Inage, Yawara Eguchi, Sumihisa Orita, Satoshi Maki, Takeo Furuya, Tsutomu Akazawa, Tetsuya Abe…

Validity and reliability of smartphone applications for measurement of hip rotation, compared with three‐dimensional motion analysis

Measurement of hip rotation is a crucial clinical parameter for the identification of hip problems and the monitoring of symptoms. The objective of this study was to determine whether the use of two smartphone...

Authors: Phob Ganokroj, Nuchanun Sompornpanich, Pichitpol Kerdsomnuek, Bavornrat Vanadurongwan and Pisit Lertwanich

Gravity determines the direction of nerve roots sedimentation in the lumbar spinal canal

To investigate the role of gravity in the sedimentation of lumbar spine nerve roots using magnetic resonance (MR) imaging of various body positions.

Authors: Jun Yang, Zhiyun Feng, Nian Chen, Zhenhua Hong, Yongyu Zheng, Jiang Yang, Tingjie Zhou, Xin Yao, Taifeng Xu and Linting Zhang

Characteristics of hip impingement syndrome in patients with multiple hereditary exostoses

This study aimed to investigate the characteristic deformities of the hip in multiple hereditary exostoses patients (MHE) and its association with the hip impingement syndrome.

Authors: Yeong-Seub Ahn, Sungmin Kim, Woo-Jong Kim, Jun-Hyuk Lim and Sung-Taek Jung

Effect of real-time ultrasound imaging for biofeedback on trunk muscle contraction in healthy subjects: a preliminary study

Real-time ultrasound imaging (RUSI) has been increasingly used as a form of biofeedback when instructing and re-training muscle contraction. However, the effectiveness of the RUSI on a single sustained contrac...

Authors: Shanshan Lin, Bo Zhu, Yiyi Zheng, Guozhi Huang, Qi Zeng and Chuhuai Wang

Treatment of the fresh central slip avulsion of the extensor tendon by bone tunnel-tendon suture: a prospective cohort study

The current evidence base for the management of central slip avulsions is limited from obtaining a best approach. The purpose of this study was to evaluate the clinical effect and feasibility of repairing the ...

Authors: Bin Wang, Yiming Lu, Tianliang Wang, Jiaxiang Gu and Naichen Zhang

Electromagnetic navigation reduces radiation exposure for retrograde drilling in osteochondrosis dissecans of the talus

Retrograde drilling in osteochondrosis dissecans (OCD) is a widely used surgical intervention. A radiation-free electromagnetic navigation system (ENS)-based method was compared with the standard freehand fluo...

Authors: Oliver D Jungesblut, Josephine Berger-Groch, Michael Hoffmann, Malte Schroeder, Kara L. Krajewski, Ralf Stuecker and Martin Rupprecht

Accuracy measures of 1.5-tesla MRI for the diagnosis of ACL, meniscus and articular knee cartilage damage and characteristics of false negative lesions: a level III prognostic study

MRI is the most accurate imaging modality for diagnosing knee pathologies. However, there is uncertainty concerning factors predicting false negative MRI, such as meniscal tear patterns as well as patient fact...

Authors: Jonathan E. J. Koch, Ron Ben-Elyahu, Basel Khateeb, Michael Ringart, Meir Nyska, Nissim Ohana, Gideon Mann and Iftach Hetsroni

Intraoperative three-dimensional imaging in ankle syndesmotic reduction

Authors: Markus Beck, Manuela Brunk, Alice Wichelhaus, Thomas Mittlmeier and Robert Rotter

Combination of high-frequency ultrasound and virtual touch tissue imaging and quantification improve the diagnostic efficiency for mild carpal tunnel syndrome

Carpal tunnel syndrome (CTS) is the most common entrapment symptom in the peripheral nerves. High-frequency ultrasound (HFUS) is widely used in the diagnosis of CTS. Virtual Touch Tissue Imaging and Quantifica...

Authors: Zhen-han Lai, Shu-ping Yang, Hao-lin Shen, Yi Luo, Xiao-han Cai, Wen-ting Jiang, Li-ping Liao, Kun-bin Wu and Guo-rong Lv

Bone erosion in the 2nd metacarpophalangeal head: association with its bone mineral density by HR-pQCT in rheumatoid arthritis patients

Rheumatoid arthritis (RA) is a chronic autoimmune disease depicted by synovial inflammation leading to local and systemic bone loss. The aim of this study was to evaluate by a HR-pQCT (High Resolution Peripher...

Authors: Camille P. Figueiredo, Mariana O. Perez, Lucas Peixoto Sales, Ana Cristina Medeiros, Valeria F. Caparbo and Rosa M. R. Pereira

Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study

Osteoporotic fractures are a major cause of morbidity in the elderly. Menopausal women represent the population with the highest risk of early osteoporosis onset, often accompanied by vertebral fractures (VF)....

Authors: Annamaria Zaia, Roberto Rossi, Roberta Galeazzi, Manuela Sallei, Pierluigi Maponi and Pietro Scendoni

What is the impact of knee morphology on posterior cruciate ligament avulsion fracture in men and women: a case control study

Several studies on the relationship between morphological parameters and traumatic diseases of the knee have already been conducted. However, few studies focused on the association between knee morphology and ...

Authors: Ning Fan, Yong-chen Zheng, Lei Zang, Cheng-gang Yang, Shuo Yuan, Peng Du, Yan-mei Liu, Qing Zhao and Jin-wei Wang

New insights into intrinsic foot muscle morphology and composition using ultra‐high‐field (7-Tesla) magnetic resonance imaging

The intrinsic muscles of the foot are key contributors to foot function and are important to evaluate in lower limb disorders. Magnetic resonance imaging (MRI), provides a non-invasive option to measure muscle...

Authors: Melinda M. Franettovich Smith, James M. Elliott, Aiman Al-Najjar, Kenneth A. Weber II, Mark A. Hoggarth, Bill Vicenzino, Paul W. Hodges and Natalie J. Collins

Is there a correlation between upper lumbar disc herniation and multifidus muscle degeneration? A retrospective study of MRI morphology

The purpose of the study is to investigate the correlation between upper lumbar disc herniation (ULDH) and multifidus muscle degeneration via the comparison of width, the cross-sectional area and degree of fat...

Authors: Chong Liu, Jiang Xue, Jingjing Liu, Gang Ma, Abu Moro, Tuo Liang, Haopeng Zeng, Zide Zhang, Guoyong Xu, Zhaojun Lu and Xinli Zhan

The role of lymphocyte-monocyte ratio on axial spondyloarthritis diagnosis and sacroiliitis staging

Axial spondyloarthritis (axial SpA) is a chronic inflammatory disorder could lead to disability due to the failure of timely treatment. The role of lymphocyte-to-monocyte ratio (LMR) in axial SpA remains uncle...

Authors: Jing Wang, Jinyu Su, Yuan Yuan, Xiaxia Jin, Bo Shen and Guoguang Lu

HEMGN and SLC2A1 might be potential diagnostic biomarkers of steroid-induced osteonecrosis of femoral head: study based on WGCNA and DEGs screening

Steroid-induced osteonecrosis of the femoral head (SONFH) is a chronic and crippling bone disease. This study aims to reveal novel diagnostic biomarkers of SONFH.

Authors: Zhixin Wu, Yinxian Wen, Guanlan Fan, Hangyuan He, Siqi Zhou and Liaobin Chen

ACTION trial: a prospective study on diagnostic Accuracy of 4D CT for diagnosing Instable ScaphOlunate DissociatioN

Early detection of scapholunate ligament (SLL) tears is essential after minor and major trauma to the wrist. The differentiation between stable and instable injuries determines therapeutic measures which aim t...

Authors: Leonie Goelz, Simon Kim, Claas Güthoff, Frank Eichenauer, Andreas Eisenschenk, Sven Mutze and Ariane Asmus

Total spine magnetic resonance imaging for detection of multifocal infection in pyogenic spondylodiscitis: a retrospective observational study

Due to the unspecific symptoms of spondylodiscitis (SpD), an early radiological examination is necessary. However, controversially discussed is the need for magnetic resonance imaging of the entire spine to ex...

Authors: Jeanette Henkelmann, Timm Denecke, Philipp Pieroh, Stephanie Einhorn, Nicolas H. von der Hoeh, Christoph-Eckhard Heyde and Anna Voelker

Adapting MRI as a clinical outcome measure for a facioscapulohumeral muscular dystrophy trial of prednisone and tacrolimus: case report

Facioscapulohumeral muscular dystrophy (FSHD) is a patchy and slowly progressive disease of skeletal muscle. MRI short tau inversion recovery (STIR) sequences of patient muscles often show increased hyperinten...

Authors: Leo H. Wang, Laura M. Johnstone, Michael Bindschadler, Stephen J. Tapscott and Seth D. Friedman

Predictive ability of pharyngeal inlet angle for the occurrence of postoperative dysphagia after occipitocervical fusion

PIA has been proven to be a predictor for postoperative dysphagia in patients who undergo occipitospinal fusion. However, its predictive effect for postoperative dysphagia in patients who undergo OCF is unknow...

Authors: Lin-nan Wang, Bo-wen Hu, Yue-ming Song, Li-min Liu, Chun-guang Zhou, Lei Wang and Xi Yang

Defining the role of TT-TG and TT-PCL in the diagnosis of lateralization of the Tibial tubercle in recurrent patellar dislocation

The radiological indicators can help doctors determine whether to make tibial tubercle transfer. But which indicator is better is still in question.

Authors: Peng Su, Nengri Jian, Beini Mao, Zhong Zhang, Jian Li and Weili Fu

Open synovectomy treatment for intra- and extraarticular localized pigmented villonodular synovitis of the knee: a case report

Pigmented villonodular synovitis (PVNS) is a rare, benign, proliferative neoplastic process that commonly affects synovial-lined anatomic spaces. The diffuse type (DPVNS) is characterized by invasion of the en...

Authors: Daoliang Xu, Jianxia Wen, Shisi Zhang and Xiaoyun Pan

Polyglucosan body myopathy 1 may cause cognitive impairment: a case report from China

Polyglucosan body myopathy 1 (PGBM1) is a type of glycogen storage disease that can cause skeletal muscle myopathy and cardiomyopathy with or without immunodeficiency due to a pathogenic mutation in the RBCK1 ...

Authors: Lin Chen, Nan Wang, Wenbin Hu, Xuen Yu, Renming Yang, Yongzhu Han, Yan Yan, Na Nian and Congbo Sha

Spondylocarpotarsal synostosis syndrome due to a novel loss of function FLNB variant: a case report

Loss of function or gain of function variants of Filamin B (FLNB) cause recessive or dominant skeletal disorders respectively. Spondylocarpotarsal synostosis syndrome (SCT) is a rare autosomal recessive disorder ...

Authors: Samina Yasin, Outi Makitie and Sadaf Naz

Imaging features of hemangioma in long tubular bones

To investigate the imaging features of hemangiomas in long tabular bones for better diagnosis.

Authors: Lei Cao, Jin-Xu Wen, Shu-Man Han, Hui-Zhao Wu, Zhi-Gang Peng, Bao-Hai Yu, Zhi-Wei Zhong, Tao Sun, Wen-Juan Wu and Bu-Lang Gao

Will virtual multidisciplinary team meetings become the norm for musculoskeletal oncology care following the COVID-19 pandemic? - experience from a tertiary sarcoma centre

Like with all cancers, multidisciplinary team (MDT) meetings are the norm in bone and soft tissue tumour (BST) management too. Problem in attendance of specialists due to geographical location is the one of th...

Authors: Raja Bhaskara Rajasekaran, Duncan Whitwell, Thomas D. A. Cosker, Christopher L. M. H. Gibbons and Andrew Carr

3D simulation of radiographic projections to test and reduce the effect of pelvic tilt on the accuracy of cross-table lateral radiography

Cross-table lateral (CL) radiography is a convenient and feasible method to assess cup version angle (VA) after total hip arthroplasty; However, pelvic tilt (PT) may contribute to its measurement inaccuracy. H...

Authors: Jie Xu, Baohua Su, Wenhui Zhang, Hao Sun, Deng Li, Zhiqing Cai, Meiyi Chen, Meiling Qiu and Ruofan Ma

Is it possible to define reference values for radiographic parameters evaluating juvenile flatfoot deformity? A case-control study

Numerous radiographic parameters are described to evaluate juvenile flexible flatfeet. Reference values for these measurements are based on few studies. The purpose of this study was to determine boundary valu...

Authors: Johannes Hamel, Hubert Hörterer and Norbert Harrasser

Three-dimensional classification of the Lenke 1 adolescent idiopathic scoliosis using coronal and lateral spinal radiographs

Classification of the spinal deformity in adolescent idiopathic scoliosis (AIS) remains two-dimensional (2D) as the spinal radiographs remain the mainstay in clinical evaluation of the disease. 3D classificati...

Authors: Saba Pasha, Victor Ho-Fung, Malcolm Eker, Sarah Nossov and Michael Francavilla