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Fig. 6 | BMC Musculoskeletal Disorders

Fig. 6

From: Activated FGFR3 suppresses bone regeneration and bone mineralization in an ovariectomized mouse model

Fig. 6

Osteogenic differentiation and mineralization of bone marrow-derived mesenchymal stem cells (BMSCs) in each group. a Representative result of alkaline phosphatase (ALP) staining for cells in cultured BMSCs in each group. b Quantitative analysis of ALP activity. Dots indicate the value of each sample and bars indicate the means and standard deviation (SD). c Representative result of Alizarin red staining of the mineralized osteoblasts in each group. d Quantitative analysis of Alizarin red staining. Dots indicate the value of each sample and bars indicate the means and SD. e Representative result of Alizarin red staining for cultured BMSCs with meclozine treatment. f Quantitative analysis of Alizarin red staining to assess the mineralization of BMSCs. Dots indicate the value of each sample and bars indicate the means and SD. Statistical significance was analyzed using one-way analysis of variance (ANOVA) with post-hoc Bonferroni correction. Statistical significance was expressed as * p < 0.05, ** p < 0.01 and *** p < 0.005

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