Fig. 2

Body weight and bone mineral density (BMD) after ovariectomy (OVX) in each group. a Body weight before and after OVX, which was performed at the age of 8 weeks. Data values are presented as means and standard error (SE). b Weight gain 8 weeks after OVX compared to that at the age of 8 weeks. Dots indicate the value of each sample and bars indicate the means and standard deviation (SD). c Weight change rate indicating the relative weight 8 weeks after OVX. Dots indicate the value of each sample and bars indicate the means and SD. d BMD after 8 weeks of OVX. Dots indicate the value of each sample and bars indicate the means and SD. Statistical significance was analyzed using two-way (a) or one-way (b and c) analysis of variance (ANOVA) with post-hoc Bonferroni correction. Statistical significance was expressed as * p < 0.05, * p < 0.01 and *** p < 0.005