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Table 2 Comparisons in clinical outcome measures between type 2 diabetes mellitus group and control group after propensity score matching

From: Does type 2 diabetes affect the efficacy of therapeutic exercises for degenerative lumbar spinal stenosis?

Outcome Measures

Diabetic (n = 41) Mean + SD (95%CI)

Control (n = 41) Mean + SD (95%CI)

Main effect of time (p)

Main effect of group (p)

Group × time interaction (p)

Primary Outcomes

     

NRS leg/10

     

 Baseline

6.2 ± 1.9 (5.9-7.0)

6.3 ± 2.1 (6.4–7.3)

   

 6 weeks

5.0 ± 1.7 (4.4–5.6)

4.2 ± 1.6 (3.6–4.6)

< 0.001

0.023

< 0.001

 12 weeks

4.6 ± 1.9 (4.1–5.3)

3.7 ± 1.6 (3.0–4.0)

   

ODI /100

     

 Baseline

35.2 ± 12.1 (32.9–41.4)

35.7 ± 13.9 (31.9–41.0)

   

 6 weeks

33.5 ± 10.2 (33.1–38.6)

34.6 ± 15.5 (29.4–38.6)

0.010

0.397

0.774

 12 weeks

31.6 ± 9.9 (29.3–36.7)

33.0 ± 15.3 (27.8–36.8)

   

Second Outcomes

     

NRS back/10

     

 Baseline

3.9 ± 1.8 (3.3–4.6)

3.8 ± 1.2 (2.8–3.7)

0.031

0.155

0.122

 6 weeks

2.9 ± 1.7 (2.3–3.4)

2.2 ± 1.2 (1.8–2.6)

   

 12 weeks

2.3 ± 1.2 (1.9–2.7)

1.9 ± 1.0 (1.6–2.2)

   

SPWT

     

 Baseline

464.4 ± 221.4 (379.6–537.0)

462.1 ± 268.1 (351.3-529.7)

   

 6 weeks

545.3 ± 178.2 (478.0-612.7)

651.4 ± 246.0 (544.0-706.3)

< 0.001

0.042

0.027

 12 weeks

612.7 ± 189.1 (552.3-682.3)

776.5 ± 269.3 (642.1-823.8)

   

SF-36 BP /100

     

 Baseline

42.1 ± 13.0 (38.1–46.5)

42.2 ± 15.8 (37.6–48)

   

 6 weeks

47.6 ± 12.2 (43.8–51.5)

48.2 ± 16.0 (43.2–53.3)

0.363

0.134

0.291

 12 weeks

49.4 ± 11.6 (45.7–53.1)

52.5 ± 16.2 (47.4–57.6)

   

SF-36 PF/100

     

 Baseline

45.2 ± 12.8 (40.1–48.6)

46.3 ± 14.9 (42.8–52.0)

   

 6 weeks

47.1 ± 13.8 (42.7–51.4)

50.0 ± 14.7 (45.3–54.6)

0.247

0.182

0.121

 12 weeks

49.9 ± 13.5 (45.7–54.2)

53.7 ± 15.3 (48.9–58.6)

   

SBI/24

     

 Baseline

12.4 ± 4.1 (11.2–12.9)

11.5 ± 4.2 (10.4–13.2)

   

 6 weeks

9.5 ± 3.8 (8.3–0.7)

8.7 ± 4.7 (7.3–10.2)

0.032

0.098

0.166

 12 weeks

8.0 ± 3.8 (6.8–9.2)

6.7 ± 3.3 (5.7–7.8)

   

TSK-11/68

     

 Baseline

44.2 ± 9.2 (40.7–46.0)

44.8 ± 14.2 (37.7–45)

   

 6 weeks

41.0 ± 7.8 (38.5–43.4)

38.3 ± 11.9 (34.6–42.1)

0.128

0.144

0.453

 12 weeks

39.6 ± 7.7 (37.2–42.0)

36.8 ± 12.7 (32.8–40.8)

   

BDI/63

     

 Baseline

7.2 ± 3.6 (6.3–8.7)

7.0 ± 4.3 (4.6 to 7.2)

   

 6 weeks

5.9 ± 4.0 (4.5–6.9)

5.7 ± 4.3 (4.1 to 6.3)

0.087

0.106

0.051

 12 weeks

5.3 ± 3.6 (4.3–6.6)

5.0 ± 3.9 (3.8 to 6.2)

   
  1. SD standard deviation, CI confidence interval. NRS: 11-point Numerical Rating Scale, the NRS leg pain and back pain is an 11-point scale where the endpoints are the extremes of “no pain” and “pain as bad as it could be”; ODI: Oswestry Disability Index, the ODI is scored from 0–100 with higher numbers indicating greater disability; SPWT: self-paced walking test, the SPWT is measured as the distance a person can walk continuously on a flat surface at a self-selected pace until being forced to stop because of symptoms of LSS, including neurogenic claudication and/or low back pain, up to a limit of 30 min; SF-36 BP/PF: SBI: Stenosis Bothersomeness Index, a 0–24 scale, with higher scores indicating more bothersome symptoms. The Index is calculated as the sum of separate 0–6 bothersomeness ratings for leg symptoms of pain, weakness, numbness, and pain after walking. TSK-11: The Tampa Scale for Kinesiophobia, TSK-11 is a widely used questionnaire to assess fear of movement. The TSK consists of 17 items, each rated on a 4-point Likert scale ranging from “strongly disagree “to strongly agree”. Four items are inversely phrased. The total sum has a minimum score of 17 (low fear) and a maximum of 68 (high fear); BDI: Beck Depression Index, BDI is a 21-item, self-report rating inventory that measures characteristic attitudes and symptoms of depression. *Statistically significant difference between groups