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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Biological effect of bone marrow mesenchymal stem cell- derived extracellular vesicles on the structure of alveolar bone in rats with glucocorticoid-induced osteoporosis

Fig. 2

Characterization of extracellular vesicles according to their size and morphology; EVs visualized by TEM showing lipid bilayer EVs (size: 94.37 nm);scale bar 100 nm (a) Evs of different sizes ranging from 78–89 nm, Scale bar; 50 nm, (b) Intensity analysis curve displaying size distribution and peak size of isolated EVs (c). Representative panel of flow cytometric cell surface markers for EVs showing the percentages of CD63 (97.75%) while that of double expressing CD9 and CD81 (97.94%) (d,e). MitoTracker red-fluorescent dye is used as a negative marker for characterizing the EVs which revealed their presence in the BM-MSCs (+ ve control) (67.11%) while they were detected in the EVs (0.73%) (f,g)

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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