Modification to Mirels scoring system location component improves fracture prediction for metastatic disease of the proximal femur

Table 1 Patient demographics and original Mirels scoring

	*Fracture (Fx)*	*No Fracture (No Fx)*	*Fx vs No Fx* t-test		*Stabilized*	*No Lesion*^a
N	8	40		N	36	10
Sex (F \| M)	7 \| 1	26 \| 14		Sex (F \| M)	20 \| 16	5 \| 5
Age (Years)	64 [42–87]	62 [23–95]	p = 0.78	Age (Years)	63 [33–88]	66 [54–88]
Weight (kg)	83 [42–142]	78 [42–142]	p = 0.66	Weight (kg)	78 [46–122]	86 [46–115]
BMI (kg/m²)	28.5 [20.3–38.8]	28.5 [16.5–61.5]	p = 0.99	BMI (kg/m²)	26.5 [16.5–43.7]	30.7 [16.9 – 39.8]
Original Mirels Score	10.5 [9,10,11,12]	8.5 [6,7,8,9,10]	p = 0.0049	Original Mirels Score	10.6 [8,9,10,11,12]	NA

Seventy-two patients with disseminated tumors to the proximal femurs (n = 84) resulted in fracture, no fracture, or were prophylactically stabilized. An additional No Lesion (^a) femur set was identified from the sample population and was used to create the finite element models with idealized spherical lesions. Mean and range shown. Two-sample t-tests indicate p-values for differences between fracture and no fracture groups

ISSN: 1471-2474