Table 3 Treatment effects on symptom outcomes

NPRS

0.009

0.41

0.133

0.001

0.17

 < 0.001

0.136

( -0.42, 1.02)

(-1.496, -0.404)

(-1.835, -0.615)

0.001

DNG(n = 42)

6.15 ± 1.48

2.10 ± 1.28^*△

2.45 ± 1.22^*△

DG(n = 35)

5.85 ± 1.75

3.05 ± 1.18^*

3.68 ± 1.51^*#

WOMAC-pain

0.042

0.068

0.081

0.01

0.165

 < 0.001

0.199

(-0.068, 1.868)

(-1.626, -0.224)

(-2.035,-0.665)

 < 0.001

DNG(n = 42)

7.85 ± 2.18

2.6 ± 1.63^*△

2.73 ± 1.38^*△

DG(n = 35)

6.95 ± 2.17

3.53 ± 1.52^*

4.08 ± 1.69^*

WOMAC-stiffness

0.003

0.640

0.097

0.005

0.175

 < 0.001

0.094

(-0.486, 0.786)

(-1.096, -0.204)

(-1.415, -0.485)

0.006

DNG(n = 42)

3.53 ± 1.50

1.38 ± 1.13^*△

1.63 ± 1.19^*△

DG(n = 35)

3.38 ± 1.35

2.03 ± 0.86^*

2.58 ± 0.87^*

WOMAC-function

0.006

0.49

0.254

 < 0.001

0.315

 < 0.001

0.174

(-2.224, 4.644)

(-10.957, -4.725)

(-10.957, -5.493)

 < 0.001

DNG(n = 42)

28.05 ± 8.18

9.13 ± 5.82^*△

11.45 ± 5.38^*△

DG(n = 35)

26.85 ± 7.27

16.83 ± 7.45^*

19.68 ± 6.81^*

WOMAC-total

0.018

0.242

0.296

 < 0.001

0.403

 < 0.001

0.251

(-1.546, 6.046)

(-12.497, -6.053)

(-13.411, -7.639)

 < 0.001

DNG(n = 42)

39.43 ± 8.96

13.1 ± 6.53^*△

15.80 ± 5.70^*△

DG(n = 35)

37.18 ± 8.07

22.38 ± 7.88^*

26.33 ± 7.18^*#

ROM

0.003

0.626

0.060

0.029

0.163

(-8.245, 4.995)

(0.792, 14.458)

 < 0.001

DNG(n = 42)

96.63 ± 15

114.50 ± 15.31^*△

DG(n = 35)

98.25 ± 14.74

106.88 ± 15.39^*