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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Neutrophil extracellular traps induce the bone erosion of gout

Fig. 1

MSU crystals induce the formation of NETs in vivo. a The concentration of DNA, NE, MPO in the MSU group was higher than the NC group on days 1, 7 and 14. *P < 0.05, **P < 0.01, ***P < 0.001 as determined by t test (n = 3). b The immunofluorescence of the joint flushing fluid (× 20) The formation of NETs (MPO+H3+DNA+) in group MSU was significantly higher than NC groups on days 1, 7 and 14. c The histopathology of tibia (× 100). There was slight inflammatory infiltration in the cartilage on 1 day, while that was relieved at 7 day and 14 days in the MSU group. d IL-1β、TNF-αwere measured with ELISA. The level of two of them were higher than NC group at 24 h, on the day 7 and 14, the comparison was no longer statistically significant. This result was consistent with c

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